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Effects of pyrethroid and organophosphate insecticides on reared black soldier fly larvae(Hermetia illucens)

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Insect Science 2024年第3期31卷 817-834页

作者： Nathan Meijer Lisa Zoet Theo de Rijk Paul Zomer Deborah Rjkers H.J.van der Fels-Klerx Joop J.A.van Loon Wageningen Food Safety Research(WFSR) Part of Wageningen University and ResearchWageningenThe Netherlands bestico b.v. Industrieweg 6Berkel en RodenrjsThe Netherlands Plant Sciences Group Laboratory of EntomologyWageningen UniversityWageningenTheNetherlands

black soldier fly larvae(Hermetia illucens)receive growing interest as a potential alternative animal feed *** insects may be exposed to insecticide residues in the rearing *** study aimed to investigate the effects of six different pyrethroid and organophosphate insecticides on this insect species'*** toxicity of two"model"substances for each of these classes(cypermethrin;pirimiphosmethyl)was quantified,with and without the synergist piperonyl butoxide(PbO).Critical effect doses corresponding to 10%yield(CED10)for cypermethrin(0.4 mg/kg)and pirimiphos-methyl(4.8 mg/kg)were *** addition of PbO to cypermethrin enhanced its relative potency with a factor *** data were compared against the relative toxicity of two analogue substances in each class(permethrin,deltamethrin;chlorpyrifosmethyl,malathion).Results suggest that exposure to concentrations complying with legal limits can cause significant reductions in *** to multiple substances at lower concentrations resulted in negative additive and synergistic *** the tested substances,deltamethrin was most toxic,causing 94%yield at 0.5 mg/*** results suggested that transfer of tested substances to the larval biomass was substance-and concentration-specific,but appeared to be correlated to reduced yields and the presence of *** of organophosphates was overall low(but ranged from 8%to 75%for *** to very low limits in insect biomass(~0.01 mg/kg),high transfer may result in *** is recommended that rearing companies implement lower contractual thresholds,and that policymakers consider adjusting legally allowed maximum residue levels in insect feed.

关键词： feed insects pesticides rearing substrate

A tribo-chemical view on astringency of plant-based food substances

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Friction 2024年第7期12卷 1392-1407页

作者： Samuel S.GAMANIEL Paloma S.DUEÑAS RObLES Hans TROMP Els H.A.de HOOG Sissi de bEER Emile van der HEIDE Laboratory for Surface Technology and Tribology Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 LWthe Netherlands NIZO Food Research b.v. Ede6710 BAthe Netherlands Department of Molecules and Materials MESA+Institute for Nanotechnology University of TwenteEnschede 7500 AEthe Netherlands

Consumption of plant-based food products having high composition of polyphenols leads to the sensation of *** sliding oral surfaces,friction is an essential property during the oral perception of roughness and dryness which are attributes associated with *** factors including the chemical composition of interacting layers,structure and operation of interfaces have an effect on the astringency development *** manner of interactions occurring at oral interfaces suggest there is a system dependence of astringency and highlights the importance of adopting a tribosystems *** measurement techniques have shown an existing relationship between salivary protein-polyphenol interaction and an astringent ***,the tribo-chemistry involved in this multifaceted sensation remains largely unexplored in a comprehensive *** this review the underlying tribo-chemical processes useful in understanding the mechanism of astringency are highlighted and discussed considering current techniques employed to investigate astringency *** of lubrication on oral surfaces owing to the tribo-chemical interactions involving saliva and astringent plant proteins requires subsequent deformations of oral tissues which are significant enough to induce strains at mechanoreceptor locations,leading to the sensation of *** is proposed that micro-scale contact modelling on the interaction of food particles/aggregates,boundary layers and oral surfaces shows potential in addressing the knowledge gap between tribo-chemical measurement techniques and panel tests,making it possible to attain a predictor for astringency.

关键词： oral lubrication astringency tribo-chemistry tribology

Liquid injectivity in a SAG foam process:Effect of permeability

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Petroleum Science 2024年第1期21卷 302-314页

作者： Jia-Kun Gong Yuan Wang Ridhwan-Zhafri b.Kamarul bahrim Raj-Deo Tewari Mohammad-Iqbal Mahamad Amir Rouhi Farajzadeh William Rossen College of Mechanics and Materials Hohai UniversityNanjing210098JiangsuChina College of Water Conservancy&Hydropower Engineering Hohai UniversityNanjing210098JiangsuChina PETRONAS Kuala Lumpur50088Malaysia Department of Geoscience and Engineering Delft University of Technology2628 CNDelftthe Netherlands Shell Global Solutions International b.v. 1031 HWAmsterdamthe Netherlands

Foam is utilized in enhanced oil recovery and CO_(2) ***-alternating-gas(SAG)is a preferred approach for placing foam into reservoirs,due to it enhances gas injection and minimizes corrosion in *** previous studies with similar permeability cores show that during SAG injection,several banks occupy the area near the well where fluid exhibits distinct ***,underground reservoirs are heterogeneous,often *** is crucial to understand the effect of permeability on fluid behaviour and injectivity in a SAG *** this work,coreflood experiments are conducted in cores with permeabilities ranging from 16 to 2300 *** observe the same sequence of banks in cores with different ***,the speed at which banks propagate and their overall mobility can vary depending on *** higher permeabilities,the gas-dissolution bank and the forced-imbibition bank progress more rapidly during liquid *** total mobilities of both banks decrease with *** utilizing a bank-propagation model,we scale up our experimental findings and compare them to results obtained using the Peaceman *** findings reveal that the liquid injectivity in a SAG foam process is misestimated by conventional simulators based on the Peaceman *** lower the formation permeability,the greater the error.

关键词： Foam Enhanced oil recovery Surfactant-alternating-gas Injectivity Permeability

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Analysis of particle dispersion and cavity formation during bulk particle water entry using fully coupled CFD-DEM-vOF approach

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Particuology 2024年第7期90卷 558-580页

作者： Utkan Çalışkan Sanja Mišković Norman b.Keevil Institute of Mining Engineering University of British Columbia2329 West MallVancouverBC V6T 1Z4Canada

This paper presents the development and validation of a fully coupled computational fluid dynamics—discrete element method—volume of fluid(CFD-DEM-vOF)model to simulate the complex behavior of particle-laden flows with free *** coupling between the fluid and particle phases is established through the implemented continuity,momentum,and alpha transport *** coupled particle forces such as drag,pressure gradient,dense virtual mass,viscous,and interface forces are also integrated,with drag and dense virtual mass forces being dependent on local *** integrated conservative alpha transport equation ensures phase volume conservation during interactions between particles and ***,we have implemented a trilinear interpolation method designed to operate on unstructured hexahedral *** method has been tested for its ability to properly resolve the coupling effects in the numerical simulations,particularly in cases with a relatively low cell-size *** model is validated through three distinct test cases:single particle water entry,dam break with particles,and water entry of a group of particles *** experimental setup is built to study the dynamics of the water entry of a group of particles,where three key flow features are analyzed:the evolution of average particle velocity,cavity shape,and particle dispersion cloud profiles in *** tests involve four different scenarios,including two different water levels(16.1 and 20.1 cm)and two different particle densities(2650 and 4000 kg/m3).High-speed videometry and particle tracking velocimetry(using ImageJ/TrackMate)methods are employed for experimental data *** is demonstrated that numerical results are in excellent agreement with theoretical predictions and experimental *** study highlights the significance of vortices in cavity shaping and particle *** validated CFD-DEM-vOF model constitutes a robust tool for simulating particle-laden flows,cont

关键词： CFD-DEM-vOF Trilinear interpolation Particle-laden flow Free-surface Particle water entry volume conservation

CD4^(+)T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors

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Cellular & Molecular Immunology 2024年第4期21卷 374-392页

作者： Xin Lei Daniël C.de Groot Marij J.P.Welters Tom de Wit Ellen Schrama Hans van Eenennaam Saskia J.Santegoets Timo Oosenbrug Annemarthe van der veen Joris L.vos Charlotte L.Zuur Noel F.C.C.de Miranda Heinz Jacobs Sjoerd H.van der burg Jannie borst Yanling Xiao Department of Immunology Leiden University Medical CenterLeidenThe Netherlands Oncode Institute Leiden University Medical CenterLeidenThe Netherlands Department of Tumor biology and Immunology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Medical Oncology Oncode InstituteLeiden University Medical CenterLeidenThe Netherlands IMMIOS b.v. OssThe Netherlands Division of Medical Oncology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Otorhinolaryngology Leiden University Medical Center LeidenThe Netherlands Department of Pathology Leiden University Medical CenterLeidenThe Netherlands

CD4^(+)T cells can"help"or"license" conventional type 1 dendritic cells(cDC1s)to induce CD8^(+)cytotoxic T lymphocyte(CTL)anticancer responses,as proven in mouse *** recently identified cDC1s with a transcriptomic imprint of CD4^(+)T-cell help,specifically in T-cell-infiltrated human cancers,and these cells were associated with a good prognosis and response to PD-1-targeting ***,we delineate the mechanism of cDC1 licensing by CD4^(+)T cells in *** CD4^(+)T cells produce IFNβvia the STING pathway,which promotes MHC-I antigen(cross-)presentation by cDC1s and thereby improves their ability to induce CTL anticancer *** cooperation with CD40 ligand(L),IFNβalso optimizes the costimulatory and other functions of cDC1s required for CTL response ***-I-producing CD4^(+)T cells are present in diverse T-cell-infiltrated cancers and likely deliver“help”signals to CTLs locally,according to their transcriptomic profile and colocalization with“helped/licensed”cDCs and tumor-reactive CD8^(+)T *** agreement with this scenario,the presence of IFN-I-producing CD4^(+)T cells in the TME is associated with overall survival and the response to PD-1 checkpoint blockade in cancer patients.

关键词： CD4^(+)T-cell help cDC1 licensing IFN-I signaling CD40 costimulation (cross-)presentation CTL priming Tumor control

vR-based digital twin for remote monitoring of mining equipment:Architecture and a case study

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虚拟现实与智能硬件（中英文） 2024年第2期6卷 100-112页

作者： Jovana PLAvŠIĆ Ilija MIŠKOvIĆNorman bKeevil Norman b.Keevil Institute of Mining Engineering University of British ColumbiaVancouverBC V6T 1Z4Canada

background Traditional methods for monitoring mining equipment rely primarily on visual inspections,which are time-consuming,inefficient,and *** article introduces a novel approach to monitoring mission-critical systems and services in the mining industry by integrating virtual reality(vR)and digital twin(DT)***-based DTs enable remote equipment monitoring,advanced analysis of machine health,enhanced visualization,and improved decision *** This article presents an architecture for vR-based DT development,including the developmental stages,activities,and stakeholders involved.A case study on the condition monitoring of a conveyor belt using real-time synthetic vibration sensor data was conducted using the proposed *** study demonstrated the application of the methodology in remote monitoring and identified the need for further development for implementation in active mining *** article also discusses interdisciplinarity,choice of tools,computational resources,time and cost,human involvement,user acceptance,frequency of inspection,multiuser environment,potential risks,and applications beyond the mining *** The findings of this study provide a foundation for future research in the domain of vR-based DTs for remote equipment monitoring and a novel application area for vR in mining.

关键词： virtual reality Digital twin Condition monitoring Mining equipment

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Effect of operational parameters on the performance of an anaerobic sequencing batch reactor(AnSbR)treating protein-rich wastewater

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Environmental Science and Ecotechnology 2024年第1期17卷 89-99页

作者： Zhe Deng Julian Muñoz Sierra Ana Lucia Morgado Ferreira Daniel Cerqueda-Garcia Henri Spanjers Jules b.v.n Lier Delft University of Technology Faculty of Civil Engineering and GeosciencesStevinweg 12628 CNDelftthe Netherlands veolia Water Technologies Techno Center Netherlands b.v.-biothane Tanthofdreef 212623 EWDelftthe Netherlands KWR Water Research Institute Groningenhaven 7P.O.Box 10723430 BBNieuwegeinthe Netherlands Institute of Ecology.A.C Cluster Cientifico y Tecnologico BioMimic®Carretera Antigua a Coatepec 351El Haya91073XalapaVeracruzMexico

Treating protein-rich wastewater using cost-effective and simple-structured single-stage reactors presents several *** this study,we applied an anaerobic sequencing batch reactor(AnSbR)to treat protein-rich wastewater from a *** focused on identifying the key factors influencing the removal of chemical oxygen demand(COD)and the settling performance of the *** AnSbR achieved a maximum total COD removal of 90%,a protein degradation efficiency exceeding 80%,and a COD to methane conversion efficiency of over 70%at organic loading rates of up to 6.2 g COD L^(-1)d^(-1).We found that the variations in both the organic loading rate within the reactor and the hydraulic retention time in the buffer tank had a significant effect on COD *** hydraulic retention time in the buffer tank and the reactor,which determined the ammonification efficiencies and the residual carbohydrate concentrations in the reactor liquid,affected the sludge ***,the genus Clostridium sensu stricto 1,known as protein-and lipids-degraders,was predominant in the *** analysis showed a significant correlation between the core microbiome and ammonification efficiency,highlighting the importance of protein degradation as the governing process in the *** results will provide valuable insights to optimise the design and operation of AnSbR for efficient treatment of protein-rich wastewater.

关键词： Anaerobic digestion Anaerobic sequencing batch reactor (AnSbR) Protein Microbial community Slaughterhouse wastewater

Suppressing filamentation instability due to laser beam self-filtering

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High Power Laser Science and Engineering 2024年第3期12卷 51-61页

作者： Dmitry Silin Efim Khazanov A.v.Gaponov-Grekhov Institute of Applied Physics of the Russian Academy of Sciences Nizhny NovgorodRussia

The development of small-scale self-focusing in a nonlinear Kerr medium after preliminary self-filtering of a laser beam propagating in free space is studied *** is shown that,under definite conditions,due to self-filtering,filamentation instability(beam splitting into filaments)either occurs at significantly larger values of the b-integral,or does not occur at *** the latter case,there develops the honeycomb instability revealed in this *** instability is the formation of a random honeycomb structure in the beam *** is shown that self-filtering can significantly increase the permissible values of the b-integral,at which the beam quality remains acceptable.

关键词： filamentation instability honeycomb instability self-filtering small-scale self-focusing

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Toward sustainable waste management in small islands developing states: integrated waste-to-energy solutions in Maldives context

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Frontiers of Environmental Science & Engineering 2024年第2期18卷 133-148页

作者： Yao Wang Alejandro Ruiz-Acevedo Eemaan Rameez vijaya Raghavan Abid Hussain Xunchang Fei School of Civil and Environmental Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798Singapore United Nations Office for Project Services(UNOPS) United Nations BuildingBuruzu MaguMale’20184Maldives Department of bioresource Engineering McGill UniversitySte-Anne-De-BellevueQuebec H9X 3V9Canada Department of Civil and Environmental Engineering Carleton UniversityOttawaOntario K1S 5B6H9X 3V9Canada

Effective waste management is a major challenge for Small Island Developing States (SIDS) like Maldives due to limited land availability. Maldives exemplifies these issues as one of the most geographically dispersed countries, with a population unevenly distributed across numerous islands varying greatly in size and population density. This study provides an in-depth analysis of the unique waste management practices across different regions of Maldives in relation to its natural and socioeconomic context. Data shows Maldives has one of the highest population density and per capita waste generation among SIDS, despite its small land area and medium GDP per capita. Large disparities exist between the densely populated capital Male’ with only 5.8 km2 area generating 63% of waste and the ~194 scattered outer islands with ad hoc waste management practices. Given Male’s dense population and high calorific waste, incineration could generate up to ~30 GW/a energy and even increase Maldives’ renewable energy supply by 200%. In contrast, decentralized anaerobic digestion presents an optimal solution for outer islands to reduce waste volume while providing over 40%–100% energy supply for daily cooking in local families. This timely study delivers valuable insights into designing context-specific waste-to-energy systems and integrated waste policies tailored to Maldives’ distinct regions. The framework presented can also guide other SIDS facing similar challenges as Maldives in establishing sustainable, ecologically sound waste management strategies.

关键词： Anaerobic digestion Waste incineration Waste management Maldives Small Island Developing States Waste-to-energy