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Transcutaneous electrical acupoint stimulation alleviates the anxiety levels of in vitro fertilization and improves the outcomes:a prospective,randomized and controlled study

Transcutaneous electrical acupoint stimulation alleviates th...

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2016全国中西医结合妇产科研究进展学术研讨会暨201...

作者： Fan Qu Lan-Feng Xing Yan Wu Yi-Jing He Ke-Lin He Chun-Mei Ma Yu-Ying Yan Sai-Jun Sun Fang-Fang Wang Yu-Hang Zhu Nicola Robinson Paul J.Hardiman Women's Hospital School of MedicineZhejiang University Zhejiang Chinese Medical University faculty of Health and Social Care London South Bank University Institute for Women's Health University College London Medical School

Objective:To explore whether transcutaneous electrical acupoint stimulation(TEAS)can relieve the anxiety levels of infertile women during the period from trans-vaginal oocyte retrieval(TVOR) to embryo transfer(ET) in in vitro fertilization(IVF) treatment and to investigate the effects of TEAS on the outcomes of ***:A prospective,randomized and controlled study was conducted in the Reproductive Medicine Center of Zhejiang Province,China.A total of 168 infertile women with tubal blockage who were referred to our center for IVF were *** women were randomized into a control group with 48 cases,a TEAS-2 Hz group with 24 cases,a TEAS-lOOHz group with 47 cases and a TEAS-2/100 Hz group with 49 cases,using a randomization chart constructed by randomizing numbers with Microsoft *** anxiety levels were rated with Spielberger’s State Trait Anxiety Inventory(STAI) and the Amsterdam Preoperative Anxiety and Information Scale(APAIS).Data of clinical pregnancy rate(CPR)implantation rate(IR) and live birth rate(LBR) were obtained for all the recruited ***:There were no.significant differences on the levels of state anxiety,preoperative anxiety(including anesthesia related anxiety and surgery related anxiety) and need-for-information among all of the four groups before *** found that 2/100 Hz TEAS treatment significantly decreased the levels of state anxiety and preoperative anxiety(including anesthesia related anxiety and surgery related anxiety) of the patients(Pno.side-effect was reported in any of the groups during the research and the follow-up ***:TEAS using a frequency of 2/100 Hz could help to alleviate the anxiety levels associated with IVF and to improve the IVF outcomes.

关键词： [Key terms]Transcutaneous electrical acupoint stimulation(TEAS) in vitro fertilization(IVF) anxiety clinical pregnancy rate(CPR) implantation rate(IR) live birth rate(LBR)

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Growth inhibition of a human colon carcino.a cell, COLO 201, by a natural product, Vitex agnus-castusfruits extract, in vivoand in vivo

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Advances in Biological Chemistry 2012年第1期2卷 20-28页

作者： Masahiko Imai Bo Yuan Hidetomo Kikuchi Mai Saito Kunio Ohyama Chieko Hirobe Takashi Oshima Takahiro Hosoya Hiroshi Morita Hiroo Toyoda Department of Clinical Molecular Genetics School of Pharmacy Tokyo University of Pharmacy & Life Sciences Tokyo Japan Department of Cultural History Seisen University Tokyo Japan faculty of Pharmaceutical Sciences Hoshi University Tokyo Japan Gastroenterological Center Yokohama City University Medical Center Yokohama Japan

An extract from ripe fruit of Vitex agnus-castus (Vitex) has been used to treat patients with various obstetric and gynecological disorders in Europe. We have demonstrated that Vitex showed cytocidal effects on various types of cancer cell lines including a human colon carcino.a cell line, COLO 201. In this study, we extended our previous study to investigate the detailed mechanisms underlying cytocidal effects of Vi- tex on COLO 201. Furthermore, a possible clinical application of Vitex was also explored in vivo using nude mice xeno.rafted with the cells. Treatment with Vitex induced apoptosis in COLO 201 in a time-dependent manner, accompanying with activa-tion of caspase-9 and -3, but no. caspase-8. An inhibitor for c-Jun NH2-terminal kinase (JNK), but no. p38 mitogen-activated protein kinase (MAPK), significantly suppressed the apoptosis induction along with caspase-3 activation. Endoplasmic reticulum (ER) stress-related genes were also upregulated by Vitex treatment. Most importantly, the in vivo efficacy of Vitex evaluated by assessing the tumor growth revealed that the administration of Vitex significantly suppressed tumor growth in COLO 201 xeno.rafted mice. Collectively, current results suggest that apoptosis induction by Vitex in COLO 201 is mediated through the activation of JNK and caspase-9, -3 resulted from ER stress. Based on the current clinical application of Vitex, these results thus provide a new insight into the clinical use of Vitex and leave open a possibility of a new regimen as an alternative medicine approach for such devastating colon cancer treatment.

关键词： Colon Cancer Apoptosis Induction ER Stress JNK Flavono.ds Vitex agnus-castus

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稀有金属伟晶岩的地球化学和岩石成因:以刚果(金)Karagwe-Ankole成矿带Kivu地区Lemera锡矿床为例

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Transactions of no.ferrous Metals Society of China 2023年第6期33卷 1873-1892页

作者： Rub’son N’nahano.Ruhindwa HERITIER Moïse LUEMBA 李欢 Charles NZOLANG Donat KAMPATA Joseph NTIBAHANANA 中南大学地球科学与信息物理学院有色金属成矿预测与地质环境监测教育部重点实验室长沙410083 中国地质大学地质过程与矿产资源国家重点实验室北京100083 中国石油大学(华东)地球科学与技术学院青岛266580 faculty of Oil Gas and New EnergiesUniversity of KinshasaB.P.127 Kinshasa XID.R.Congo Official University of Bukavu BukavuSouth KivuD.R.Congo National Geological Service Ministry of MinesKinshasaD.R.Congo Geophysical Research Center Ministry of Research and Technological InnovationKinshasaD.R.Congo

本文报道刚果(金)Karagwe-Ankole成矿带Kivu地区Lemera花岗伟晶岩型锡矿床的岩石成因和地球化学研究结果。从露头采集7个花岗岩伟晶岩样品,并采用ICP-MS和XRF光谱法对其进行全岩岩石地球化学分析。花岗伟晶岩具有较高的Al_(2)O_(3)、较... 详细信息

本文报道刚果(金)Karagwe-Ankole成矿带Kivu地区Lemera花岗伟晶岩型锡矿床的岩石成因和地球化学研究结果。从露头采集7个花岗岩伟晶岩样品,并采用ICP-MS和XRF光谱法对其进行全岩岩石地球化学分析。花岗伟晶岩具有较高的Al_(2)O_(3)、较低的Fe_(2)O_(3)(T)和MgO含量(平均值分别为12.95%、0.96%和0.16%,质量分数),岩石铝饱和指数范围为1.33~2.05。一些重要稀有金属的丰度以及相关关键参数计算结果如下:Sn((1~138)×10^(-6))、Ta((0.20~0.60)×10^(-6))、Nb((1~8)×10^(-6))、Cs((1.20~3.20)×10^(-6))、Rb((3~223)×10^(-6))、Zr((7~201)×10^(-6));w(K)/w(Rb)(150~272);w(K)/w(Cs)(9.06~23.3),w(Nb)/w(Ta)(3.33~14)。结果表明,Lemera花岗伟晶岩形成于碰撞后期至后碰撞的构造环境中,由过铝质S型花岗岩岩浆结晶而成,岩浆经历了强烈的分离结晶作用。该岩体具有锡和锆的矿化。

关键词： Kibaran成矿带 Lemera花岗伟晶岩锡矿床 S型花岗岩分离结晶

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Kno.ledge, Attitude and Practice of Breast Self-Examination amongst Women in Two Communities of Cameroon

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Open Journal of Obstetrics and Gynecology 2021年第6期11卷 773-793页

作者： Florent Ymele Fouelifack Rene Pierre Binyom Anyimbi Mosman Ofeh Jeanne Hortence Fouedjio Robinson Eno. Mbu Department of Obstetrics and Gynecology of Higher Institute of Medical Techno.ogy of Nkolondom Yaounde Cameroon Obstetrics and Gynecology Unit of Yaounde Central Hospital Yaounde Cameroon Research Education and Health Associative Group GARES-Falaise Dschang Cameroon Department of Surgery Higher Institute of Medical Technology of Nkolondom Yaounde Cameroon Department of Obstetrics and Gynecology Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon

Breast cancer is a major health problem in the world. It is the most common cancer in women and is equally the leading cause of cancer death in women. Though in controversy Breast self-examination (BSE) remains a useful tool in early diagno.is of breast cancer. The aim of this study was to evaluate the kno.ledge, attitude and practice of BSE amongst women in Yaoundé and Monatele. We carried out a cross sectional study in two communities of Cameron over a period of eight months, targeting females older than 15 years. After obtaining authorization, we randomly interviewed 402 consenting participants, using a pretested questionnaire. Data were entered using CS Pro 7.3 and analysed using SPSS 23. Of a total of 402 participants, 256 (63.7%) in Monatele and 146 (36.3%) in Yaoundé VI, the mean age was 26.55 ± 9.57 years. Exactly 50% (201) had earlier heard of BSE. Health personnel and media represented the main sources of information on BSE. Of the total, 46 (11.4%) knew BSE should be done monthly. Fifty-three percent had poor kno.ledge and 51.0% had a generally low attitude towards BSE. Out of 402 participants, 65.2% reported no. practicing BSE. For those practicing, 71.6% had poor practices. The main reason for no. practicing was lack of kno.ledge. Poor kno.ledge increased poor practice. In conclusion half of the women had heard about BSE even though the majority had a poor kno.ledge on BSE and very low overall attitude and practice. Health personnel and media played a key role in passing of information. Increasing the number of health campaigns, multiplying TV shows and health talks about breast self-examination will improve kno.ledge and hence attitude and practice.

关键词： Kno.ledge Attitude Practice Breast Self-Examination

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Scald Burns in Children. An Analysis with Special Attention to the Roma Ethnic Group in East Slovakia

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International Journal of Clinical Medicine 2015年第1期6卷 44-49页

作者： Eugen Frisman Oliver Rácz Jozefina Petrovicová Ján Slávik Iveta Cimboláková Clinic of Burns and Reconstructive Surgery 1st Private Hospital Kosice-Saca Slovakia Department of Pathophysiology Medical School Safárik University Kosice Slovakia faculty of Healthcare Miskolc University Miskolc Hungary Department of Medical Informatics Medical School Safárik University Kosice Slovakia Department of Anaesthesiology and Intensive Care Medicine 1st Private Hospital Kosice-Saca Slovakia

Objectives: A retrospective analysis of scald burns in children in a region with a significant prevalence of Roma ethnicity living in poor socioecono.ic situation. Patients: During 3 year period 273 children were admitted to the Clinic of Burns and Reconstructive Surgery of our hospital;201 of them were with scald burns accounting for 73.6% of all pediatric burn admissions. More than half (58.7%) of the 201 children with scald burns were of Roma ethnicity. Results: The average BSAB of the children with scald burns was 10.8%;mean length of hospital stay 11.5 days. 58.7% of the children with scald burns was of Roma ethnicity. The no.-scald admissions of children had a similar pattern but these children were older and with an even higher prevalence of Roma patients (75%), a slightly lower average BSAB (9.8%) and a significantly longer need of hospital treatment (average 15.7 days). Conclusion: The frequency of scald burn injuries in very young Roma children in our region is very high. Prevention of scald burns is possible only through targeted and well-organized education of this vulnerable population.

关键词： Scald Burns Pediatric Burns Roma Ethnicity

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稀有金属伟晶岩的地球化学和岩石成因:以刚果(金)Karagwe-Ankole成矿带Kivu地区Lemera锡矿床为例（英文）

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Transactions of no.ferrous Metals Society of China 2023年第6期 1873-1892页

作者： Rub’son N’nahano.Ruhindwa HERITIER Mo?se LUEMBA 李欢 Charles NZOLANG Donat KAMPATA Joseph NTIBAHANANA 中南大学地球科学与信息物理学院有色金属成矿预测与地质环境监测教育部重点实验室中国地质大学地质过程与矿产资源国家重点实验室中国石油大学(华东)地球科学与技术学院 faculty of Oil Gas and New Energies University of Kinshasa National Geological Service Ministry of Mines 6. Geophysical Research Center Ministry of Research and Technological Innovation

本文报道刚果(金)Karagwe-Ankole成矿带Kivu地区Lemera花岗伟晶岩型锡矿床的岩石成因和地球化学研究结果。从露头采集7个花岗岩伟晶岩样品,并采用ICP-MS和XRF光谱法对其进行全岩岩石地球化学分析。花岗伟晶岩具有较高的Al2O3、较低的Fe2... 详细信息

本文报道刚果(金)Karagwe-Ankole成矿带Kivu地区Lemera花岗伟晶岩型锡矿床的岩石成因和地球化学研究结果。从露头采集7个花岗岩伟晶岩样品,并采用ICP-MS和XRF光谱法对其进行全岩岩石地球化学分析。花岗伟晶岩具有较高的Al2O3、较低的Fe2O3(T)和MgO含量(平均值分别为12.95%、0.96%和0.16%,质量分数),岩石铝饱和指数范围为1.33～2.05。一些重要稀有金属的丰度以及相关关键参数计算结果如下:Sn((1～138)×10-6)、Ta((0.20～0.60)×10-6)、Nb((1～8)×10-6)、Cs((1.20～3.20)×10-6)、Rb((3～223)×10-6)、Zr((7～201)×10-6);w(K)/w(Rb)(150～272);w(K)/w(Cs)(9.06～23.3),w(Nb)/w(Ta)(3.33～14)。结果表明,Lemera花岗伟晶岩形成于碰撞后期至后碰撞的构造环境中,由过铝质S型花岗岩岩浆结晶而成,岩浆经历了强烈的分离结晶作用。该岩体具有锡和锆的矿化。

关键词： Kibaran成矿带 Lemera花岗伟晶岩锡矿床 S型花岗岩分离结晶

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Anti-CD163-dexamethasone conjugate inhibits the acute phase response to lipopolysaccharide in rats

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World Journal of Hepatology 2016年第17期8卷 726-730页

作者： Karen Louise Thomsen Holger Jon Moller Jonas Heilskov Graversen Nils E Magnusson Soren K Moestrup Hendrik Vilstrup Henning Gronbaek Department of Hepatology and Gastroenterology Aarhus University Hospital Department of Clinical Biochemistry Aarhus University Hospital Affinicon Aps Incuba Science Park Institute of Molecular Medicine University of Southern Denmark Department of Clinical Medicine Faculty of HealthMedical Research LaboratoryAarhus University Department of Biomedicine University of Aarhus

AIM: To study the effect of a new anti-CD163-dexamethasone conjugate targeting activated macrophages on the hepatic acute phase response in rats. METHODS: Wistar rats were injected intraveno.s with either the CD163 targeted dexamethasone-conjugate(0.02 mg/kg) or free dexamethasone(0.02 or 1 mg/kg) 24 h prior to lipopolysaccharide(LPS)(2.5 mg/kg intraperitoneal). We measured plasma concentrations of tumour necrosis factor-a(TNF-a) and interleukin 6(IL-6) 2 h post-LPS and liver m RNAs and serum concentrations of the rat acute phase protein a-2-macroglobulin(a-2-M) 24 h after LPS. Also, plasma concentrations of alanine amino.ransferase and bilirubin were measured at termination of the study. Spleen weight served as an indicator of systemic steroid ***: The conjugate halved the a-2-M liver m RNA(3.3 ± 0.6 vs 6.8 ± 1.1, P 201 ± 48 μg/mL vs 389 ± 67 μg/mL, P = 0.04) after LPS compared to low dose dexamethasone treated animals, while no.e of the free dexamethasone doses had an effect on liver m RNA or serum levels of a-2-M. Also, the conjugate reduced TNF-a(7208 ± 1977 pg/mL vs 21583 ± 7117 pg/mL, P = 0.03) and IL-6(15685 ± 3779 pg/mL vs 25715 ± 4036 pg/mL, P = 0.03) compared to the low dose dexamethasone. The high dose dexamethasone dose decreased the spleen weight(421 ± 11 mg vs 465 ± 12 mg, P no. seen in any other ***: Low-dose anti-CD163-dexamethasone conjugate effectively decreased the hepatic acute phase response to LPS. This indicates an anti-inflammatory potential of the conjugate in vivo.

关键词： Acute phase response Dexamethasone Endotoxin Hemoglobin scavenger receptor CD163 Cytokines Inflammation Rats

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日本全国范围内各种显像剂实际使用剂量的调查报告

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中华核医学与分子影像杂志 2017年第7期37卷 445-445页

作者：唐军 Hiroshi Watanabe Kazunari Ishii Makoto Hosono.Etsuko Imabayashi Koichiro Abe Masayuki Inubushi Kazuko Ohno.Yasuhiro Magata Kinya Ono.Kei Kikuchi Kei Wagatsuma Tadashi Takase Kyoko Saito Yasuyuki Takahashi 苏州大学附属第二医院核医学科 Department of Radiological Techno.ogy Japan Labour Health and Welfare Organization Yokohama Rosai Hospital Department of Radiology Kindai University Faculty of Medicine

目的医疗照射的最优化在世界范围内都是辐射防护所关心的重要问题之一,国际辐射防护委员会和国际原子能机构推荐建立显像剂使用的剂量参考水平（DRLs）作为控制医疗照射最优化的工具。因此,根据最新调查资料构建DRLs已成为各核医学相关... 详细信息

目的医疗照射的最优化在世界范围内都是辐射防护所关心的重要问题之一,国际辐射防护委员会和国际原子能机构推荐建立显像剂使用的剂量参考水平（DRLs）作为控制医疗照射最优化的工具。因此,根据最新调查资料构建DRLs已成为各核医学相关学会和组织的迫切需要。为构建此DRLs,本研究在全日本范围内调查了核医学成人用显像剂的实际使用剂量。方法调查在2014年11月25日至2015年1月16日间进行,使用调查表方式调查了全日本1249个医疗单位各种显像剂的使用情况,调查结果通过网络反馈收集。结果 516个医疗单位反馈了调查结果,反馈率41%。具体显像包括:99Tcm-MDP和99Tcm-HMDP的骨显像,99Tcm-HM-PAO、99Tcm-ECD和123I-IMP的脑血流显像,99Tcm-Tetrofosmin、99Tcm-MIBI和201Tl-Cl的心肌灌注显像,18F-FDG(自产18F或配送的18F)的肿瘤PET显像。以上显像的第75百分剂量分别是为932、937、763、775、200、831、818、180、235和252 MBq。日本90%以上的医疗单位所使用的显像剂剂量在上述剂量值中位数的50%范围内。很多医疗机构采用包装说明书、文本或指南推荐的剂量,比如740 MBq(99Tcm-MDP和99Tcm-HMDP骨显像)、740 MBq(99Tcm-ECD和99Tcm-HM-PAO脑血流显像)和740 MBq(99Tcm-Tetrofosmin和99Tcm-MIBI心肌灌注显像)等。99Tcm-MDP和99Tcm-HMDP（用于骨显像）、99Tcm-HM-PAO（用于脑血流显像）、99TcmTetrofosmin和99Tcm-MIBI（用于心肌灌注显像）等许多显像剂的使用剂量均在欧盟DRLs内,且大多数在日本使用的显像剂剂量均未超过美国核医学与分子影像学会的标准使用剂量上限。结论本调查结果表明,在日本所使用的各种核医学显像剂的剂量比较集中,各医疗机构均能按照文本和指南要求的剂量越来越严格地使用显像剂。此外,日本显像剂的使用剂量均在欧盟和美国核医学与分子影像学会所规定的使用剂量范围内。

关键词：调查诊断参考水平放射性药物放射性活度剂量最优化

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用间接心率监控测量仪对能量消耗的评价与比较(英文)

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Journal of Sport and Health Science 2012年第3期1卷 178-183,195页

作者： Zhusheng Yu Eszter Volgyi Ru Wang Andrea Ember Petri Wiklund Markku Alen Frances ATylavsky Sulin Cheng School of Kinesiology Shanghai University of Sport Shanghai 200438China Department of Health Sciences University of JyvsaylFIN-40014 Jyvsayl Finland Department of Preventive Medicine University of Tennessee Health Science Center:MemphisTN 38163USA School of Kinesiology Shanghai University of Sport Shanghai 200438China Department of Health Sciences University of JyvsaylFIN-40014 JyvsaylFinland faculty of Physical Education and Sport Sciences Semmelweis University BudapestAlkots U44Hungary Department of Medical Rehabilitation Oulu University Hospital and Institute of Health SciencesUniversity of OuluFIN-90029 OuluFinland Department of Preventive Medicine University of Tennessee Health Science CenterMemphisTN 38163USA

目的:采用新开发的总能量消耗的评价方法与传统方法进行比较。方法:对象共46人,其中16名中年男性(平均年龄51.4岁),14名中年女性(平均年龄49.9岁)和16名年轻女性(平均年龄19.1岁)。使用新开发的软件(2011年芬兰Oy公司出产MoveSense心率... 详细信息

目的:采用新开发的总能量消耗的评价方法与传统方法进行比较。方法:对象共46人,其中16名中年男性(平均年龄51.4岁),14名中年女性(平均年龄49.9岁)和16名年轻女性(平均年龄19.1岁)。使用新开发的软件(2011年芬兰Oy公司出产MoveSense心率监测分析仪),对24小时的心率能耗数据进行监控,并与用双标水法测得的数据进行对照比较。用BlandAltman对两种测定方法之间的一致性程度进行分析。结果:发现两种测定方法在群体水平中得出的能量消耗值相似,平均为-8.6kcal/天,而在个体水平中存在较大差异,46例研究对象中有44例(96%,)能量消耗值在±2SD范围内,出现平均下降趋势,并没有任何过高或过低倾向。结论我们的研究结果表明,目前每日评价能耗的心率软件系统尚需进一步研发,以适用于独立个体。

关键词：双标水心率监控男性和女性总能量消耗

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Alternate Two Different Modes of Actions of Green Chemicals to Combat Batrachedra amydraula Meyrick and Cadra cautella Walk on Date Palm Fruit, Egypt

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Journal of Agricultural Science and Techno.ogy(A) 2014年第6期4卷 529-534页

作者： Ahmed Amin Sayed Sobhy Ahmed Temerak Salah Mahmood Mohmed Gameel Amr Moussa Plant Protection Research Institute Agricultural Research Center Ministry of Agricu#ure (MOA) Cairo 11728 Egypt Plant Protection Department Faculty of Agriculture Assiut University Assiut 71515 .Egypt Plant Protection Research Institute Agricultural Research Center MOA Cairo 11728 Egypt Research & Development Department Dow Agro Sciences Company Indianapolis 46268 USA

Alternate two different modes of actions of green chemicals: spino.ad & methoxyfeno.ide to combat the lesser date moth, Batrachedra amydraula and the Almond moth, Cadra cautella Walk on dates in Dakhla Oasis, New Valley, Egypt were done in 2010 and 2011. Based on infestation of the early insect pest B. amydraula, the three-rotation program with basic 1st spray of spino.ad 24 SC at 20 mL/100 L showed insignificant difference. Based on minimum effective rotation doses, alternating spino.ad 24 SC at 20 mL/100 L, then methoxyfeno.ide 24 SC at 15 mL/100 L with two-week interval showed zero infestation and 1.8% at the last sample of 2010 and 2011, respectively. Based on infestation of the late insect pest, Cadra spp., the same previous trend of the three-rotation results. Based on minimum effective rotation doses, alternating spino.ad 24 SC at 20 mL/100 L, then methoxyfeno.id 24 SC at 15 mL/100 L with three-week interval indicated less than 1% and 1% infestation during harvest for 2010 and 2011, respectively. The last reflected important value when storing the fruit. Both products proved to be working under dry hot high temperatures.

关键词：绿色化学品备用多杀菌素防治操作棕榈埃及有效剂量

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