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Oxygen heterocyclic compounds(OHCs) in lemon oils are important markers in targeted HPLC analyses for authentication

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Food Science and Human Wellness 2024年

作者： Siyu Liu Shiming Li Chi-Tang Ho Department of Food Science， Rutgers University New Brunswick college of Biology and Agricultural Resources， Huanggang Normal University

Lemon oils are broadly used as flavoring agents in beverages， foods， cosmetics and pharmaceuticals， yet the adulteration of natural， particularly cold pressed lemon oils is very common in the industry due to its unmet demand and high cost. Nowadays， most quality control (QC) analysis of lemon oils is conducted by gas chromatography (GC) analysis， which is far from a reliable method. Oxygen heterocyclic compounds (OHCs) in non-volatile fraction are gaining increasing attention in authentication process because of the nearly finger-printing profiles of OHCs in cold pressed citrus essential oils. Our goal in this study was to identify OHCs using high performance liquid chromatography (HPLC) in lemon oils， establish OHC profiles， perform stepwise logistic regression analysis (SLRA) and build effective predicting model and further determine adulterated lemon oils by referencing the OHC profiles and established models. After HPLC analyses， profiling and SLRA modeling of 154 OHCs samples of industrial lemon oils， we found that the combination of isopimpinellin and total OHC concentration are essential and robust predictors to differentiate authentic samples from adulterated lemon oils with a success rate of 98% from the 5-fold cross validation. This study provided a reliable and efficient method in determining the authenticity of lemon oils.

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Piperine regulates the circadian rhythms of hepatic clock gene expressions and gut microbiota in high-fat diet-induced obese rats

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Food Science and Human Wellness 2024年第3期13卷 1617-1627页

作者： Weiyun Zhang Chi-Tang Ho Wenlian Wei Jie Xiao Muwen Lu Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods College of Food ScienceSouth China Agricultural UniversityGuangzhou 510642China Department of Food Science Rutgers UniversityNew Brunswick 08901USA

The interplay between the host circadian clock and microbiota has significant influences on host metabolism processes,and circadian desynchrony triggered by high-fat diet(HFD)is closely related to metabolic *** this study,the modulatory effects of piperine(PIP)on lipid metabolism homeostasis,gut microbiota community and circadian rhythm of hepatic clock gene expressions in obese rats were *** Sprague-Dawley(SD)rats were fed with normal diet(ND),HFD and HFD supplemented with PIP,*** 9 weeks,rats were sacrificed with tissue and fecal samples collected for circadian *** showed that chronic PIP administration ameliorated the obesity-induced alterations in lipid metabolism and dysregulation of hepatic clock gene expressions in obese *** gut microbial communities studied through 16S rRNA sequencing showed that PIP ameliorated the imbalanced nicrobiota and recovered the circadian rhythm of Lactobacillaceae,Desulfovibrionaceae,Paraprevotellaceae,and *** fecal metabolic profiles indicated that 3-dehydroshikimate,cytidine and lithocholyltaurine were altered,which were involved in the amino acid and fatty acid metabolism *** findings could provide theoretical basis for PIP to work as functional food to alleviate the lipid metabolism disorder,circadian rhythm misalignment,and gut microbiota dysbiosis with wide applications in the food and pharmaceutic industries.

关键词： Piperine Circadian clock Obesity Gut microbiota

What diameter?What height?Influence of measures of average tree size on area-based allometric volume relationships

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Forest Ecosystems 2024年第1期11卷 100-109页

作者： Yilin Wang John A.Kershaw Mark J.Ducey Yuan Sun James B.McCarter Integrated Forest Mensuration and Systems Analysis Laboratory Faculty of Forestry and Environmental ManagementUniversity of New BrunswickFrederictonNBCanada Department of Natural Resources and the Environment University of New HampshireDurhamNHUSA college of Forestry Nanjing Forestry UniversityNanjing210037China Scientific Programmer RayonierYuleeFLUSA

Volume is an important attribute used in many forest management *** from 83 fixed-area plots located in central new brunswick,Canada,are used to examine how different measures of stand-level diameter and height influence volume prediction using a stand-level variant of Honer's(1967)volume *** density was included in the models(Volume=f(Diameter,Height,Density))choice of diameter measure was more important than choice of height *** density was not included(Volume=f(Diameter,Height)),the opposite was *** models with density included,moment-based estimators of stand diameter and height performed better than all other *** models without density,largest tree estimators of stand diameter and height performed better than other *** overall best equation used quadratic mean diameter,Lorey's height,and density(root mean square error=5.26 m^3·ha^(-1);1.9%relative error).The best equation without density used mean diameter of the largest trees needed to calculate a stand density index of 400 and the mean height of the tallest 400 trees per ha(root mean square error=32.08 m^(3)·ha^(-1);11.8%relative error).The results of this study have some important implications for height subsampling and LiDAR-derived forest inventory analyses.

关键词： Allometric relationships Stand structure Volume estimation Stand-level attributes

Effects of alcohol on digestion,absorption and metabolism of sea cucumber saponins in healthy mice

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Food Science and Human Wellness 2024年第1期13卷 137-145页

作者： Wenxian Dang Rong Li Jinyue Yang Changhu Xue Qingrong Huang Yuming Wang Tiantian Zhang college of Food Science and Engineering Ocean University of ChinaQingdao 266003China Laboratory for Marine Drugs and Bioproducts Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China Department of Food Science Rutgers State University New BrunswickNJ 08901USA

Sea cucumber saponins have attracted more attention in recent years due to biological *** is a popular practice to soak sea cucumber in Baijiu at home and being applied to industrial manufacturing in ***,knowledge of the effect of alcohol on the absorption and metabolism of sea cucumber saponins is *** effects of alcohol on digestion,absorption and metabolism of sea cucumber saponins in BALB/c mice were investigated after gavage and tail intravenous *** results showed that the content of saponins in serum and liver was significantly higher under the influence of alcohol than that in the control group after oral *** promoted the absorption of sea cucumber saponins prototype as well as inhibited the process of saponins being transformed into deglycositic metabolites in the small ***,sea cucumber saponins remained in circulation for a long time and alcohol slowed down the clearance of sea cucumber saponins under the influence of alcohol after intravenous *** confirmed the feasibility of marinating sea cucumber in Baijiu to improve the efficacy of saponins and provides an important theoretical basis for the utilization of sea cucumber and the development of sea cucumber liquor.

关键词： Holothurin A Echinoside A Alcohol Absorption Metabolism

Bioactive phytochemicals and associated multifunctional health-promoting effects of Polygonati Rhizoma

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Food Science and Human Wellness 2024年

作者： Shuzhen Wang Feng He Yunli Xiao Fu Xiang Lan Lu Wei Wu Chi-Tang Ho Shiming Li college of Biology and Agricultural Resources， Huanggang Normal University School of Computer and Information Technology， Beijing Jiaotong University Department of Food Science， Rutgers University New Brunswick

Polygonati Rhizoma， a functional food and a traditional Chinese medicine broadly used in China and several Southeast Asia countries， possesses effective health-promoting activities. Prepared from three plants in Polygonatum family (P. kingianum， P. sibiricum， and P. cyrtonema)， Polygonati Rhizoma has drawn increasing attention due to its remarkable immune-enhancing and metabolic regulatory activities in recent years. In this review， we summarized the updated research of chemical constituents and biological activities of Polygonati Rhizoma， especially the metabolic regulation， immunomodulatory effects， and anti-fatigue activities， aiming to provide a comprehensive understanding， broaden the usage and promote more in-depth exploration of Polygonati Rhizoma as a functional food.

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Multi-layer hierarchical cellulose nanofibers/carbon nanotubes/vinasse activated carbon composite materials for supercapacitors and electromagnetic interference shielding

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Nano Research 2024年第3期17卷 904-912页

作者： Tianxu Wang Chuanyin Xiong Yongkang Zhang Bo Wang Qing Xiong Mengjie Zhao Yonghao Ni college of Bioresources Chemical&Materials Engineering Shaanxi University of Science and TechnologyXi’an 710021China Department of Chemical and biomedical Engineering The University of MaineOronoME 04469USA University of new brunswick Limerick Pulp&Paper CtrFrederictonNB E3B 5A3Canada

Developing porous self-supporting electrodes with excellent conductivity,good mechanical properties,and high electrochemical activity is crucial for constructing electrode materials with lightweight,ultra-thin,flexible,and high capacitance *** this work,we prepared a cellulose nanofibers(CNFs)/carbon nanotubes(CNTs)/vinasse activated carbon(VAC)(CCV)composite material with a multi-layer hierarchical conductive structure through simple vacuum filtration and *** this composite material,the self-assembly of CNF provides the main skeleton structure of a multi-layer hierarchical *** provides a fast path for the rapid transfer of electrons and is beneficial for the loss of electromagnetic *** provides sufficient double layer *** synergistic effect of the above three endows CCV composite materials with excellent energy storage performance and electromagnetic interference(EMI)shielding *** addition,we endowed the CCV composite with a certain shape and performance by introducing a vitrimer polymer with a dynamic cross-linked network *** summary,thanks to the synergistic effect of various components in the multi-layer hierarchical structure,CCV composite materials exhibit excellent integration performance,especially stable energy storage performance and EMI shielding *** significant properties make CCV composite materials have great application prospects in the fields of energy storage and intelligent EMI shielding.

关键词： self-supporting electrodes multi-layer hierarchical structure supercapacitors electromagnetic interference shielding

Antiglycating effects of citrus flavonoids and associated mechanisms

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Food Science and Human Wellness 2024年第5期13卷 2363-2372页

作者： Yunli Xiao Junfeng Shen Jianfeng Zhan Limin Guo Chi-Tang Ho Shiming Li college of Biology and Agricultural Resources Huanggang Normal UniversityHuanggang 438000China Institute of Agro-Products Storage and Processing Xinjiang Academy of Agricultural SciencesUrumqi 830091China Department of Food Science Rutgers UniversityNew Brunswick 08901USA

Glycation of proteins and DNA forms advanced glycation end products(AGEs)causing cell and tissue dysfunction and subsequent various chronic diseases,in particular,metabolic and age-related *** AGE inhibition includes scavengers of reactive carbonyl species(RCS)such as methylglyoxal(MG),glyoxalase-1 enhancers,Nrf2/ARE pathway activators,AGE/RAGE formation inhibitors and other antiglycatng *** flavonoids have demonstrated antioxidant and anti-inflammatory effects and are also found to be effective antiglycating ***,we reviewed the up to date progress of the antiglycation effects of citrus flavonoids and associated *** citrus flavonoids,hesperedin and its aglycone,hesperetin,inhibited glycation by scavenging MG forming mono-or di-flavonoid adducts with MG,enhanced the activity of glyoxase-1,activated Akt/Nrf2 signal pathway while inhibiting AGE/RAGE/NF-κB pathway,reduced the formation of Nε-(carboxylmethyl)lysine(CML)and pentosidine,inhibited aldol reductase activity and decreased the levels of *** antiglycating activity and mechanisms of other flavonoids was also summarized in this *** conclusion,citrus flavonoids possess effective antiglycating activity via different mechanisms,yet there are many challenging questions remaining to be studied in the near future such as in vivo testing and human study of citrus flavonoids for efficacy,effectiveness and adverse effects of citrus flavonoids as a functional food in managing high levels of AGEs and controlling AGE-induced chronic diseases,diabetic complications in particular.

关键词： Citrus flavonoids Hesperedin Advanced glycation end products Antiglycation Diabetic complication

Storylines of family medicine Ⅱ:foundational building blocks—context,community and health

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Family Medicine and community Health 2024年第S3期12卷 12-22页

作者： William B Ventres Leslie A Stone Rupal Shah Tamala Carter Geoffrey M Gusoff Winston Liaw Bich-May Nguyen Joanna V Rachelson Mary Alice Scott Teresa L Schiff-Elfalan Seiji Yamada Robert C Like Kathleen Zoppi A Peter Catinella Richard M Frankel Shailendra Prasad Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Bridge Lane Group Practice LondonUK Penn Center for community Health Workers University of PennsylvaniaPhiladelphiaPennsylvaniaUSA National Clinician Scholars Program UCLA David Geffen School of MedicineLos AngelesCaliforniaUSA Health Systems and Population Health Sciences University of Houston Tilman J Fertitta Family College of MedicineHoustonTexasUSA Southern new Mexico Family Medicine Residency Program Las CrucesNew MexicoUSA new Mexico Primary Care Training Program Silver CityNew MexicoUSA Anthropology New Mexico State UniversityLas CrucesNew MexicoUSA Family Medicine and community Health University of Hawai'i at Manoa John A Burns School of MedicineHonoluluHawaiiUSA Family Medicine and community Health Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA Family Medicine Indiana University School of MedicineIndianapolisIndianaUSA Family Medicine–Transmountain Texas Tech University Health Sciences CenterEl PasoTexasUSA Medicine Indiana University School of MedicineIndianapolisIndianaUSA Family Medicine and community Health University of Minnesota Medical School-Twin Cities CampusMinneapolisMinnesotaUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅱ:foundational building blocks—context,community and health’,authors address the following themes:‘Context—grounding family medicine in time,place and being’,‘Recentring community’,‘community-oriented primary care’,‘Embeddedness in practice’,‘The meaning of health’,‘Disease,illness and sickness—core concepts’,‘The biopsychosocial model’,‘The biopsychosocial approach’and‘Family medicine as social medicine.’May readers grasp new implications for medical education and practice in these essays.

关键词： thematic illustration dimensions

Supposition of graphene stacks to estimate the contact resistance and conductivity of nanocomposites

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 663-676页

作者： Y.ZARE M.T.MUNIR G.J.WENG K.Y.RHEE Biomaterials and Tissue Engineering Research Group Department of Interdisciplinary TechnologiesBreast Cancer Research CenterMotamed Cancer InstituteTehran ***Iran college of Engineering and Technology American University of the Middle EastEgaila 54200Kuwait Department of Mechanical and Aerospace Engineering Rutgers UniversityNew BrunswickNJ 08903U.S.A. Department of Mechanical Engineering(BK21 Four) College of EngineeringKyung Hee UniversityYongin 446701Republic of Korea

In this study,the effects of stacked nanosheets and the surrounding interphase zone on the resistance of the contact region between nanosheets and the tunneling conductivity of samples are evaluated with developed equations superior to those previously *** contact resistance and nanocomposite conductivity are modeled by several influencing factors,including stack properties,interphase depth,tunneling size,and contact *** developed model's accuracy is verified through numerous experimental *** further validate the models and establish correlations between parameters,the effects of all the variables on contact resistance and nanocomposite conductivity are ***,the contact resistance is primarily dependent on the polymer tunnel resistivity,contact area,and tunneling *** dimensions of the graphene nanosheets significantly influence the conductivity,which ranges from 0 S/m to90 S/*** increased number of nanosheets in stacks and a larger gap between them enhance the nanocomposite's ***,the thicker interphase and smaller tunneling size can lead to higher sample conductivity due to their optimistic effects on the percolation threshold and network efficacy.

关键词： graphene polymer composite stacked nanosheet tunneling conductivity contact resistance interphase