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An empirical method for joint inversion of wave and wind parameters based on SAR and wave spectrometer data

Acta Oceanologica Sinica 2024年第5期43卷 133-144页

作者： Yong Wan Xiaona Zhang Shuyan Lang Ennan Ma Yongshou Dai College of Oceanography and Space informatics China University of PetroleumQingdao 266580China National Satellite Marine Application center Beijing 100081China Key Laboratory of Space Ocean Remote Sensing and Application Ministry of Natural ResourcesBeijing 100081China College of Control Science and Engineering China University of PetroleumQingdao 266580China

Synthetic aperture radar(SAR)and wave spectrometers,crucial in microwave remote sensing,play an essential role in monitoring sea surface wind and wave ***,they face inherent limitations in observing sea surface *** systems,for instance,are hindered by an azimuth cut-off phenomenon in sea surface wind field *** spectrometers,while unaffected by the azimuth cutoff phenomenon,struggle with low azimuth resolution,impacting the capture of detailed wave and wind field *** study utilizes SAR and surface wave investigation and monitoring(SWIM)data to initially extract key feature parameters,which are then prioritized using the extreme gradient boosting(XGBoost)*** research further addresses feature collinearity through a combined analysis of feature importance and correlation,leading to the development of an inversion model for wave and wind parameters based on XGBoost.A comparative analysis of this model with ERA5 reanalysis and buoy data for of significant wave height,mean wave period,wind direction,and wind speed reveals root mean square errors of 0.212 m,0.525 s,27.446°,and 1.092 m/s,compared to 0.314 m,0.888 s,27.698°,and 1.315 m/s from buoy data,*** results demonstrate the model’s effective retrieval of wave and wind ***,the model,incorporating altimeter and scatterometer data,is evaluated against SAR/SWIM single and dual payload inversion methods across different wind *** comparison highlights the model’s superior inversion accuracy over other methods.

关键词： synthetic aperture radar(SAR) wave spectrometer extreme gradient boosting(XGBoost) joint inversion method wave and wind parameters

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Magnetic Topological Dirac Semimetal Transition Driven by SOC in EuMg_(2)Bi_(2)

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Chinese Physics Letters 2024年第1期41卷 63-67页

作者：王佳萌钱浩吉姜琦乔山叶茂 State Key Laboratory of Functional Materials for informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China research center for Intelligent Chips and Devices Zhejiang LabHangzhou 311121China center for Transformative Science ShanghaiTech UniversityShanghai 201210China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

Magnetic topological semimetals have been at the forefront of condensed matter physics due to their ability to exhibit exotic transport *** the interplay between magnetic and topological orders in systems with broken time-reversal symmetry is crucial for realizing non-trivial quantum *** delve into the electronic structure of the rare-earth-based antiferromagnetic Dirac semimetal EuMg_(2)Bi_(2) using first-principles calculations and angle-resolved photoemission *** calculations reveal that the spin-orbit coupling(SOC)in EuMg_(2)Bi_(2) prompts an insulator to topological semimetal transition,with the Dirac bands protected by crystal *** linearly dispersive states near the Fermi level,primarily originating from Bi 6p orbitals,are observed on both the(001)and(100)surfaces,confirming that EuMg_(2)Bi_(2) is a three-dimensional topological Dirac *** research offers pivotal insights into the interplay between magnetism,SOC and topological phase transitions in spintronics applications.

关键词： spectroscopy topological Dirac

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Glucose-mediated mitochondrial reprogramming by cholesterol export at TM4SF5-enriched mitochondria-lysosome contact sites

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Cancer Communications 2024年第1期44卷 47-75页

作者： Ji Eon Kim So-Young Park Chulhwan Kwak Yoonji Lee Dae-Geun Song Jae Woo Jung Haesong Lee Eun-Ae Shin Yangie Pinanga Kyung-hee Pyo Eun Hae Lee Wonsik Kim Soyeon Kim Chang-Duck Jun Jeanho Yun Sun Choi Hyun-Woo Rhee Kwang-Hyeon Liu Jung Weon Lee Department of Pharmacy College of PharmacySeoul National UniversitySeoulRepublic of Korea research Institute of Pharmaceutical Sciences College of PharmacySeoul National UniversitySeoulRepublic of Korea BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit College of Pharmacy and Research Institute of Pharmaceutical SciencesKyungpook National UniversityDaeguRepublic of Korea Department of Chemistry Seoul National UniversitySeoulRepublic of Korea College of Pharmacy Chung-Ang UniversitySeoulRepublic of Korea natural product informatics research center Korea Institute of Science and Technology(KIST)Gangneung-siGangwon-doRepublic of Korea School of Life Sciences Gwangju Institute of Science and Technology(GIST)GwangjuRepublic of Korea Department of Biochemistry College of MedicineDong-A UniversityBusanRepublic of Korea Global AI Drug Discovery center College of Pharmacy and Graduate School of Pharmaceutical SciencesEwha Womans UniversitySeoulRepublic of Korea Interdisciplinary Program in Genetic Engineering Seoul National UniversitySeoulRepublic of Korea

Background:Transmembrane 4 L six family member 5(TM4SF5)translocates subcellularly and functions metabolically,although it is unclear how intracellu-lar TM4SF5 translocation is linked to metabolic *** is thus of interests to understand how the traffic dynamics of TM4SF5 to subcellular endosomal membranes are correlated to regulatory roles of ***:Here,we explored the metabolic significance of TM4SF5 localization at mitochondria-lysosome contact sites(MLCSs),using in vitro cells and in vivo animal systems,via approaches by immunofluorescence,proximity labelling based proteomics analysis,organelle reconstitution ***:Upon extracellular glucose repletion following depletion,TM4SF5 became enriched at MLCSs via an interaction between mitochondrial FK506-binding protein 8(FKBP8)and lysosomal *** labeling showed molecular clustering of phospho-dynamic-related protein I(DRP1)and certain mitophagy receptors at TM4SF5-enriched MLCSs,leading to mitochondrial fis-sion and ***4SF5 bound NPC intracellular cholesterol transporter 1(NPC1)and free cholesterol,and mediated export of lysosomal cholesterol to mitochondria,leading to impaired oxidative phosphorylation but intact tri-carboxylic acid(TCA)cycle andβ-*** mouse models,hepatocyte Tm4sf5 promoted mitophagy and cholesterol transport to mitochondria,both with positive relations to liver ***:Our findings suggested that TM4SF5-enriched MLCSs regu-late glucose catabolism by facilitating cholesterol export for mitochondrial reprogramming,presumably while hepatocellular carcinogenesis,recapitulating aspects for hepatocellular carcinoma metabolism with mitochondrial repro-gramming to support biomolecule synthesis in addition to glycolytic energetics.

关键词： cholesterol fluorescent imaging glucose catabolism hepatocellular carcinogenesis mem-brane contact sites mitochondria function mitophagy oxidative phosphorylation protein-protein interaction tetraspanin

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Three-dimensional thermohaline structure estimation derived from HY-2 satellite data over the Maritime Silk Road and its applications

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Acta Oceanologica Sinica 2024年第5期43卷 41-53页

作者： Zhiqiang Chen Xidong Wang Xiangyu Wu Yuan Cao Zikang He Dakui Wang Jian Chen Key Laboratory of Marine Hazards Forecasting Ministry of Natural ResourcesHohai UniversityNanjing 210024China Laboratory for Regional Oceanography and Numercial Modeling Qingdao Marine Science and Technology CenterQingdao 266061China National Marine Environmental Forecasting center Ministry of Natural ResourcesBeijing 100081China Beijing Institute of Applied Meteorology Beijing 100029China

Estimated ocean subsurface fields derived from satellite observations provide potential data sources for operational marine environmental monitoring and prediction *** study employs a statistic regression reconstruction method,in combination with domestic autonomous sea surface height and sea surface temperature observations from the Haiyang-2(HY-2)satellite fusion data,to establish an operational quasi-realtime three-dimensional(3D)temperature and salinity products over the Maritime Silk *** products feature a daily temporal resolution and a spatial resolution of 0.25°×0.25°and exhibit stability and *** have demonstrated the accuracy of the reconstructed thermohaline fields in capturing the 3D thermohaline variations through comprehensive statistical evaluations,after comparing them against Argo observations and ocean analysis data from *** results illustrate that the reconstructed fields effectively represent seasonal variations in oceanic subsurface structures,along with structural changes resulting from mesoscale processes,and the upper ocean’s responses to tropical ***,the incorporation of HY-2 satellite observations notably enhances the accuracy of temperature and salinity reconstructions in the Northwest Pacific Ocean and marginally improves salinity reconstruction accuracy in the North Indian Ocean when compared to the World Ocean Atlas 2018 monthly climatology thermohaline *** a result,the reconstructed product holds promise for providing quasi-real-time 3D temperature and salinity field information to facilitate fast decisionmaking during emergencies,and also offers foundational thermohaline fields for operational ocean reanalysis and forecasting *** contributions enhance the safety and stability of ocean subsurface activities and navigation.

关键词： HY-2 satellite observations subsurface structures reconstruction Maritime Silk Road operational thermohaline product

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Characteristics of super drought in Southwest China and the associated compounding effect of multiscalar anomalies

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Science China Earth Sciences 2024年第7期67卷 2084-2102页

作者： Lin WANG Wen CHEN Gang HAUNG Ting WANG Qiulin WANG Xiaoyun SU Zixuan REN Chakrit CHOTAMONSAK Atsamon LIMSAKUL Kritanai TORSRI CAS Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Heavy Rain and Drought-Flood Disasters in Plateau and Basin Key Laboratory of Sichuan Province Chengdu 610072China Department of Atmospheric Science Yunnan UniversityKunming 650500China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Carbon Neutrality research center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Hangzhou Meteorological Bureau Hangzhou 310051China center for Monsoon System research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Department of Geography Faculty of Social SciencesChiang Mai UniversityChiang Mai 50200Thailand Environmental Science research center Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Climate Change and Environmental research center TechnopolisKlong 5Klong LuangPathumthani 12120Thailand Hydro-informatics Innovation Division Hydro-Informatics InstituteMinistry of Higher EducationScienceResearch and InnovationBangkok 10900Thailand

In recent decades,Southwest China(SWC)has suffered from frequent super droughts,leading to severe economic losses and ecological *** study investigates the characteristics of super droughts in SWC during 1961-2022,reveals the compounding effect of multiscalar anomalies,and explores the plausible atmospheric circulation mechanisms *** nature of super drought is a compound drought caused by the superposition of extreme drought events across multiple time *** contrasting the typical drought cases in 2006 and 2022,the decisive role of multiscalar drought compounding is *** on the Comprehensive Multiscalar Index(CMI),multiple super drought events in SWC were identified to be temporally clustered during *** them,the decadal background of enhanced evaporation and precipitation deficit at long time scales is a necessary condition for shaping the overall pattern of super droughts,while the precipitation and evaporation anomalies at short time scales trigger the outbreak of super droughts,determining the exact timing of *** events include August-September 2006,November 2009 to May 2010,July-October 2011,April-May 2012,January-April 2013,*** results suggest that the contribution of superposed precipitation anomalies to super drought is 2.4 times that of *** regards the circulation mechanisms affecting multiscalar precipitation,the anomalous spatial patterns at short-term and long-term scales are similar,featuring the cyclonic circulation over the South China Sea and the northeasterly wind anomalies together with the subsidence center over *** 2006-2014,the possible causes for the cross-seasonal persistent precipitation reduction in SWC are the extreme negative phase of the Pacific Decadal Oscillation(PDO)in the North Pacific as well as the pronounced warming of the warm pool in the western *** key dynamic processes are outlined as *** the one hand,the negative PDO p

关键词： Super drought Multiscalar Compounding effect Mechanism analysis Southwest China

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A survey on federated learning:a perspective from multi-party computation

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Frontiers of Computer Science 2024年第1期18卷 93-103页

作者： Fengxia LIU Zhiming ZHENG Yexuan SHI Yongxin TONG Yi ZHANG Institute of Artificial Intelligence and Key Laboratory of Mathematics informatics Behavioral Semantics Beihang UniversityBeijing 100191China State Key Laboratory of Software Development Environment and Advanced Innovation center for Future Blockchain and Privacy Computing Beihang UniversityBeijing 100191China Pengcheng Laboratory Shenzhen 518055China Zhongguancun Laboratory Beijing 100190China Institute for Mathematical Sciences and Engineering research center of Financial Computing and Digital Engineering Renmin University of ChinaBeijing 100872China

Federated learning is a promising learning paradigm that allows collaborative training of models across multiple data owners without sharing their raw *** enhance privacy in federated learning,multi-party computation can be leveraged for secure communication and computation during model *** survey provides a comprehensive review on how to integrate mainstream multi-party computation techniques into diverse federated learning setups for guaranteed privacy,as well as the corresponding optimization techniques to improve model accuracy and training *** also pinpoint future directions to deploy federated learning to a wider range of applications.

关键词： sfederated learning multi-party ycomputation privacy-preserving data mining distributed learning

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The Correlation between Nutrition and Transport Mechanism under Abiotic Stress in Plants: A Comprehensive Review

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Phyton-International Journal of Experimental Botany 2024年第6期93卷 1325-1344页

作者： Muhammad Saleem Jianhua Zhang Muhammad Qasim Rashid Iqbal Li Song Joint International research Laboratory of Agriculture and Agri-product Safety The Ministry of Education of ChinaJiangsu Key Laboratory of Crop Genomics and Molecular BreedingYangzhou UniversityYangzhou225009China Microelement research center College of Resources and EnvironmentHuazhong Agricultural UniversityWuhan430070China Department of Agronomy Faculty of Agriculture and EnvironmentThe Islamia University of BahawalpurBahawalpur63100Pakistan

Variations in the nutrients and water that plants require for metabolism,development,and the maintenance of cellular homeostasis are the main causes of abiotic stress in *** has,however,hardly ever been studied how these transporter proteins,such as aquaporin which is responsible for food and water intake in cell plasma mem-branes,interact with one *** review aims to explore the interactions between nutrient transporters and aquaporins during water and nutrient *** also investigates how symbiotic relationships inﬂuence the plant genome’s responses to regulatory processes such as photoperiodism,senescence,and nitrogenﬁ*** responses are observed in reaction to various abiotic *** instance,plasma membrane transporters are upregulated during macronutrient insufﬁciency,tonoplast transporters are overexpressed,and aquaporins are downregulated in micronutrient deﬁ***,tolerant plants often exhibit increased expression of nutrient transporters and aquaporins in response to drought,salt,and cold *** better comprehend plant stress tolerance to abiotic challenges including starvation,K famine,salt,and freezing temperatures,both classes of nutrient and water transporters should be considered at the same time.

关键词： Nutrients abiotic stress aquaporin transporters

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B-COPNA resin formation from ethylene tar light fractions:Process development and mechanical exploration by molecular simulation

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Chinese Journal of Chemical Engineering 2024年第6期70卷 118-129页

作者： Hongyan Shen Lingrui Cui Xingguo Wei Yuanqin Zhang Lian Cen Jun Xu Fahai Cao Engineering research center of Large Scale Reactor East China University of Science and TechnologyShanghai 200237China

An efficient utilization strategy of ethylene tar(ET),the main by-product of the ethylene cracking unit,is urgently required to meet demands for modern petrochemical *** the other hand,condensed polynuclear aromatic resin of moderate condensation degree(B-COPNA)is a widely used carbon material due to its superb processability,the production of which is,however,seriously limited by the high cost of raw *** such context,an interesting strategy was proposed in this study for producing B-COPNA resin using crosslinked light fractions of ethylene tar(ETLF,boiling pointproducts were then investigated to optimize the *** reaction mechanism of resin production was studied by analyzing the molecular structure and transition state of ETLF and crosslinking *** was shown that PXG exhibited a superior capacity of withdrawing electrons and a higher electrophilic reactivity than other crosslinking *** addition to the highest yield and greatest heat properties,PXG-prepared resin contained the most condensed *** corresponding optimized conditions of resin preparation were 180℃,1:1.9(PXG:ETLF),and 3%(mass)of catalyst content with a resin yield of 78.57%.It was the electrophilic substitution reaction that occurred between the ETLF and crosslinking agent molecules that were responsible for the resin formation,according to the experimental characterization and molecular ***,it was confirmed that the proposed strategy and demonstrated process can achieve a clean and high value-added utilization of ETLF via B-COPNA resin preparation,bringing huge economic value to the current petrochemical industry.

关键词： Ethylene tar Crosslinking COPNA resin Molecular simulation Transient state

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Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano(Trachinotus ovatus) inoculated with Bacillus subtilis: Influence of indigenous strains on lipid changes

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Food Science and Human Wellness 2024年

作者： Yanyan Wu Huifang Wang Huan Xiang Di Wang Chunsheng Li Shengjun Chen Yongqiang Zhao Yueqi Wang Key Laboratory of Aquatic product Processing Ministry of Agriculture and Rural Affairs National R&D center for Aquatic product Processing South China Sea Fisheries research Institute Chinese Academy of Fishery Sciences Guangxi Colleges and Univerisities Key Laboratory Development and High-value Utilization of Buibu Gulf Seafood Resources College of Food Engineering Beibu Gulf University Co-Innovation center of Jiangsu Marine Bio-industry Technology Jiangsu Ocean University Collaborative Innovation center of Seafood Deep Processing Dalian Polytechnic University

Inoculated fermentation enables rapid fermentation of aquatic products. No studies have been conducted on the lipid profiles of inoculated fermented golden pompano (Trachinotus ovatus). In this study， a lipase-producing Bacillus subtilis with salt tolerance was screened from traditionally fermented golden pompano (TF) and used as a starter culture. Whole-genome sequencing analysis revealed it carries four CRISPR structures and two genes encoding triacylglycerol lipase. Untargeted lipidomics identified lipid molecules (833) in six major classes from B. subtilis SCSMX-2 fermented golden pompano (IF). Twenty-eight lipid molecules were upregulated in IF， including phosphatidylcholines (PCs)， triacylglycerols (TAGs)， and lysophosphatidylcholine. B. subtilis supplementation enhanced the production of polyenyl phosphatidylcholines and medium- and long-chain triacylglycerols. The IF rich in linoleic， docosahexaenoic acids， and eicosapentaenoic acid were primarily distributed in the sn-2 position of DHA， PC and PE. This research revealed the lipid profiles of IF， providing theoretical basis for the application of B. subtilis in the fermented fish industry.

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Genomic characterization of peritoneal lavage cytology-positive gastric cancer

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Chinese Journal of Cancer research 2024年第1期36卷 66-77页

作者： Zhouqiao Wu Tingfei Gu Changxian Xiong Jinyao Shi Jingpu Wang Ting Guo Xiaofang Xing Fei Pang Ning He Rulin Miao Fei Shan Yuan Zhou Ziyu Li Jiafu Ji Key Laboratory of Carcinogenesis and Translational research(Ministry of Education/Beijing) Gastrointestinal Cancer CenterPeking University Cancer Hospital&InstituteBeijing 100142China Department of Biomedical informatics Department of Physiology and PathophysiologyCenter for Noncoding RNA MedicineMOE Key Lab of Cardiovascular SciencesSchool of Basic Medical SciencesPeking UniversityBeijing 100191China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchGastrointestinal Cancer CenterPeking University Cancer Hospital&InstituteBeijing 100142China

Objective: Positive peritoneal lavege cytology(CY1) gastric cancer is featured by dismal prognosis, with high risks of peritoneal metastasis. However, there is a lack of evidence on pathogenic mechanism and signature of CY1and there is a continuous debate on CY1 therapy. Therefore, exploring the mechanism of CY1 is crucial for treatment strategies and targets for CY1 gastric ***: In order to figure out specific driver genes and marker genes of CY1 gastric cancer, and ultimately offer clues for potential marker and risk assessment of CY1, 17 cytology-positive gastric cancer patients and 31matched cytology-negative gastric cancer patients were enrolled in this study. The enrollment criteria were based on the results of diagnostic laparoscopy staging and cytology inspection of exfoliated cells. Whole exome sequencing was then performed on tumor samples to evaluate genomic characterization of cytology-positive gastric ***: Least absolute shrinkage and selection operator(LASSO) algorithm identified 43 cytology-positive marker genes, while Mut Sig CV identified 42 cytology-positive specific driver genes. CD3G and CDKL2 were both driver and marker genes of CY1. Regarding mutational signatures, driver gene mutation and tumor subclone architecture, no significant differences were observed between CY1 and negative peritoneal lavege cytology(CY0).Conclusions: There might not be distinct differences between CY1 and CY0, and CY1 might represent the progression of CY0 gastric cancer rather than constituting an independent subtype. This genomic analysis will thus provide key molecular insights into CY1, which may have a direct effect on treatment recommendations for CY1and CY0 patients, and provides opportunities for genome-guided clinical trials and drug development.

关键词： Cytology gastric carcinoma peritoneal metastasis whole exome sequencing

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