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Occupational risk of exposure to methicillin-resistant Staphylococcus aureus(MRSA)and the quality of infection hygiene in nursing homes

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Frontiers of environmental Science & Engineering 2021年第3期15卷 111-121页

作者： Pil Uthaug Rasmussen Katrine Uhrbrand Mette Damkjaer Bartels Helle Neustrup Dorina Gabriela Karottki Ute Biiltmann Anne Mette Madsen national research Centre for the working environment Lerso Parkalle 1052100 Copenhagen 0Denmark Department of Clinical Microbiology Hvidovre HospitalKettegdrd Alle 302650 HvidovreDenmark The Danish working environment Authority Landskronagade 332100 CopenhagenDenmark University Medical center Groningen Department of Health SciencesCommunity&Occupational MedicineUniversity of Groningen9700 GroningenThe Netherlands

Methicillin-resistant Staphylococcus aureus(MRSA)is an increasing health concern across the globe and is often prevalent at long-term care facilities,such as nursing ***,we know little of whether nursing home staff is exposed to MRSA via air and *** investigated whether staff members at nursing homes are colonised with and exposed to culturable MRSA,and assessed staff members'self-reported knowledge of MRSA and compliance with infection hygiene *** nursing homes with MRSA positive residents were visited in Copenhagen,*** bioaerosol exposure samples and environmental samples from surfaces,sedimented dust and bioaerosols were examined for MRSA and methicillin-suscqjtible ***(MSSA)to determine occupational *** were taken from staffs*nose,throat,and hands to determine whether they were colonised with *** online questionnaire about MRSA and infection control was *** staff members were colonised with MRSA,but MRSA was detected in the rooms of the colonised residents in two out of the five nursing *** was observed in air(n=4 out of 42,ranging from 2.9-1.9 CFU/m^(3)),sedimented dust(n=1 out of 58,1.1 ×10^(3) CFU/m^(2)/d),and on surfaces(n=9 out of 113,0.04-70.8 CFU/m^(2)).The questionnaire revealed that half of the staff members worry about spreading MRSA to *** aspects for improvement were improved availability and use of protective equipment,not transferring cleaning supplies(e.g.,vacuum cleaners)between residents'rooms and to reduce worry of MRSA,e.g.,through education.

关键词： Antibiotic resistance Airborne MRSA Bioaerosols Healthcare-associated infections Healthcare worker Occupational health

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Haplotypes of nine single nucleotide polymorphisms on chromosome 19q13.2-3 associated with susceptibility of lung cancer in a Chinese population

Haplotypes of nine single nucleotide polymorphisms on chromo...

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遗传学进步与人口健康高峰论坛

作者： Ulla Vogel national research center for working environment lerso parkalle 105 DK-2100 Copenhagen ODenmark

To evaluate the join effect of nine single nucleotide polymorphisms for three DNA repair genes in the region 19q13.2-3 on susceptibility of lung cancer in a Chinese population,we conducted a hospital-based case-control study consisted of 247 lung cancer cases and 253 cancer-free controls matched on age,gender and ***-RFLP was used for genotyping. Associations between the baplotypes and susceptibility of lung cancer were *** global test of baplotype association revealed a statistically significant difference between cases and controls (global test:chi2=60.45,df=15,P=2.11e-07).The two of those were negative associations (Hap5 and Hap12).The three of those were positive associations (Hap3,Hap4,and Hap10).

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