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Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

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Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang national Key laboratory of Chinese Medicine modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe laboratory of modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina national Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

Vector meson's spin alignments in high energy reactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 5-20页

作者： Jin-Hui Chen Zuo-Tang Liang Yu-Gang Ma Xin-Li Sheng Qun Wang Key laboratory of Nuclear Physics and Ion-beam Application (MoE) Institute of Modern PhysicsFudan University Institute of Frontier and Interdisciplinary Science Key Laboratory of Particle Physics and Particle Irradiation (MOE)Shandong University INFN-Firenze Department of modern Physics University of Science and Technology of China School of Mechanics and Physics Anhui University of Science and Technology

The global spin alignment of vector mesons has been observed by the STAR collaboration at the Relativistic Heavy Ion Collider （RHIC） at Brookhaven national laboratory （BNL）.It provides a unique opportunity to probe the correlation between the polarized quark and antiquark in the strongly coupled quark-gluon plasma （sQGP） produced in relativistic heavy ion collisions,opening a new window to explore the properties of s *** addition,spin alignments of vector mesons have also been observed in other high-energy particle collisions such as e+e-annihilations at high energies where hadron production is dominated by quark fragmentation *** results obtained are quite different from those obtained in heavy ion collisions where quark coalescence/combination mechanism dominates suggesting strong dependence on hadronization *** comprehensive studies in different hadronization processes are *** this article,we present a brief review of theoretical and experimental advances in the study of vector meson’s spin alignments in a variety of high-energy particle collisions,with emphasis on hadronization mechanisms.

关键词： vector meson spin alignment global polarization relativistic heavy ion collisions fragmentation

Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

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Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao Zhang Li Jia Xiu-Jun Zhan Charity Ngina Qing-Rui Zhang Xiao-Ge Li Qi-Bao Jiang Shi Bai Miao-Miao Jiang national Key laboratory of Chinese Medicine modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe laboratory of modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

Robust Quantum Secure Direct Communication over Collective Rotating Channel

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communications in Theoretical Physics 2010年第4期53卷 645-647页

作者：秦素娟高飞温巧燕朱甫臣 State Key laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications national laboratory for modern communications

A quantum secure direct communication protocol over a collective rotating channel is proposed. The protocol encodes logical bits in noiseless subspaces, and so it can function over a quantum channel subjected to an arbitrary degree of collective rotating noise. Although entangled states are used, both the sender and receiver are only required to perform single-particle product measurement or Pauli operations. The protocol is feasible with present-day technique.

关键词： quantum secure direct communication collective rotating channel quantum cryptography

Robust Multiparty Quantum Secret Sharing against Participant Forcible Manipulation

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communications in Theoretical Physics 2010年第7期54卷 89-92页

作者：孙莹温巧燕朱甫臣 State Key laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications national laboratory for modern communications

The security of the multiparty quantum secret sharing protocol proposed by Gao [***,***.52 (2009) 421] is *** is shown that this protocol is vulnerable since the agents' imperfectencryption scheme can be attacked by a powerful *** introduce a attack strategy called participant forciblemanipulation and analyze the information leakage in this protocol under this *** last,we give an improved versionof the original *** improved protocol is robust and has the same efficiency as the original one.

关键词： two-level systems quantum secret sharing quantum information

Deep learning based user scheduling for massive MIMO downlink system

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Science China(Information Sciences) 2021年第8期64卷 66-75页

作者： Xiaoxiang YU Jiajia GUO Xiao LI Shi JIN The national communications Research laboratory Southeast University

In this paper, we investigate a user scheduling algorithm for massive multiple-input multipleoutput(MIMO) systems over more general correlated Rician fading channels. To achieve low latency and high throughput, a new user scheduling algorithm based on deep learning(DL) is proposed, which exploits only statistical channel state information. The proposed scheduling network is trained to grasp the mapping from the statistical signal and interference pattern to the user scheduling decision through supervised *** can predict the optimal scheduling scheme from statistical CSI without iterative calculation after offline training. Simulation results demonstrate the superior performance of the proposed algorithm in terms of calculation time, and it achieves almost the same throughput as the optimal scheduling algorithm which is obtained through exhaustive search. Furthermore, with the normalization of the input data, the proposed scheduling network is robust to the change of the channel environment and the number of transmit antennas.

关键词： massive MIMO deep learning statistical CSI user scheduling

Teleportation attack on the QSDC protocol with a random basis and order

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Chinese Physics B 2008年第9期17卷 3189-3193页

作者：高飞温巧燕朱甫臣 State Key laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications State Key laboratory of Integrated Services Network Xidian University national laboratory for modern communications

The quantum secure direct communication （QSDC） protocol with a random basis and order is analysed and an effective attack, i.e. teleportation attack, is presented. An eavesdropper can obtain half of the transmitted secret bits with the help of this special attack. It is shown that quantum teleportation can be employed to weaken the role of the order-rearrangement encryption at least in a certain circumstance. Meanwhile, a possible improvement on this protocol is proposed, which makes it secure against this kind of attack.

关键词： quantum secure direct communication quantum cryptography cryptanalysis teleportation

Secure authentication of classical messages with single photons

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Chinese Physics B 2009年第8期18卷 3189-3192页

作者：王天银温巧燕朱甫臣 State key laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications School of Mathematical Science Luoyang Normal University national laboratory for modern communications

This paper proposes a scheme for secure authentication of classical messages with single photons and a hashed function. The security analysis of this scheme is also given, which shows that anyone cannot forge valid message authentication codes （MACs）. In addition, the lengths of the authentication key and the MACs are invariable and shorter, in comparison with those presented authentication schemes. Moreover, quantum data storage and entanglement are not required in this scheme. Therefore, this scheme is more efficient and economical.

关键词： message authentication codes single photons hash function

Precise Transformation of Feistel to SP Fuse into LFSR

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China communications 2009年第4期6卷 168-171页

作者： Luo Lan Qu Zehui Song Chaoming School of Computer Science and Technology University of Electronic Science Technology of China ＆ National Laboratory for Modern Communications Chengdu China

For the published block cipher algorithm, two kinds of round functions have been *** ciphers in network environments are taking more risks than ever before because of their initialization key's distribution in the *** security of block cipher algorithm is affected by linear bias and nonlinear bias which are restricted by confusion layer and diffusion *** article takes an approach on how block cipher's two round structures are initially transformed when they fuse into *** SP structure can be considered two F functions in one Feistel round function which combines both right and left of origin data ***, the round number linear function and nonlinear function of Feistel and SP structure are *** merit of SP structure is that it can fuse in LFSR as a nonlinear filter without memory.

关键词： block cipher algorithm precise transformation merit of SP structure fuse in LFSR