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Staring-imaging satellite pointing estimation based on sequential ISAR images

Chinese Journal of Aeronautics 2024年第8期37卷 261-276页

作者： Canyu WANG Libing JIANG Weijun ZHONG Xiaoyuan REN Zhuang WANG national Key Laboratory of Automatic Target Recognition National University of Defense TechnologyChangsha 410073China Xi’an Satellite Control center Xi’an 710600China

Pointing estimation for spacecraft using Inverse Synthetic Aperture Radar(ISAR)images plays a significant role in space situational awareness and ***,feature extraction and cross-range scaling of ISAR images create bottlenecks that limit performances of current estimation ***,the emergence of staring imaging satellites,characterized by complex kinematic behaviors,presents a novel challenge to this *** address these issues,this article proposes a pointing estimation method based on Convolutional Neural Networks(CNNs)and a numerical optimization algorithm.A satellite’s main axis,which is extracted from ISAR images by a proposed Semantic Axis Region Regression Net(SARRN),is chosen for investigation in this article due to its unique ***,considering the kinematic characteristic of the staring satellite,an ISAR imaging model is established to bridge the target pointing and the extracted *** on the imaging model,pointing estimation and cross-range scaling can be described as a maximum likelihood estimation problem,and an iterative optimization algorithm modified by using the strategy of random sampling-consistency check and weighted least squares is proposed to solve this ***,the pointing of targets and the cross-range scaling factors of ISAR images are *** experiments based on actual satellite orbital parameters verify the effectiveness of the proposed *** work can improve the performance of satellite reconnaissance warning,while accurate cross-range scaling can provide a basis for subsequent data processes such as 3D reconstruction and attitude estimation.

关键词： Staring-imaging Agile satellite Inverse Synthetic Aperture Radar(ISAR) Pointing estimation Cross-range scaling

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Prognostic significance of SOX2 for chemotherapeutic patients with oral squamous cell carcinoma

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Journal of Pharmaceutical Analysis 2024年第4期14卷 619-621页

作者： Xuefeng Zhang Hao Xu Tong Zhou Xiaodong Feng Qianming Chen State Key Laboratory of Oral Diseases National Center of StomatologyNational Clinical Research Center for Oral DiseasesWest China Hospital of StomatologySichuan UniversityChengdu610041China

Oral squamous cell carcinoma(OSCC)is the most common oral cancers worldwide,accounting for over 90%of all oral malignancies[1].Despite encouraging improvements in therapeutic approaches,including surgical resection,chemotherapy,and radiotherapy,the five-year overall survival rate of OSCC has not been improved significantly over the past decades,mainly due to the high ratio of tumor recurrence and metastasis.

关键词： SOX2 therapeutic squamous

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Comprehensive characterization of cell disulfidptosis in human cancers:An integrated pan-cancer analysis

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Genes & Diseases 2024年第4期11卷 5-8页

作者： Guo Zhao Yale Jiang Yuning Wang Shuhang Wang Ning Li Clinical Trial center National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Excessive accumulation of disulfide molecules,like cystine,can induce disulfide stress and high toxicity in cells,but the reduced form of nicotinamide adenine dinucleotide phosphate can reverse this process and mitiga... 详细信息

关键词： disulfide cancer characterization

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Haploids can be induced in knockout mutants of OsPLA1,but not OsDMP3 or OsDMP6,in rice

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The Crop Journal 2024年第1期12卷 213-221页

作者： Zongkai Liu Yu Zhong Xiaolong Qi Tai An Shuwei Guo Dong Wang Yuwen Wang Bin Feng Zuofeng Zhu Shaojiang Chen Chenxu Liu national Maize Improvement center Engineering Research Center of Ministry of EducationChina Agricultural UniversityBeijing 100193China national center for Evaluation of Agricultural Wild Plants(Rice) Department of Plant Genetics and BreedingChina Agricultural UniversityBeijing 100193China

Doubled haploid(DH)technology is an important tool in crop breeding because it can significantly accelerate the breeding ***1/MATL/NLD and ZmDMP are two key genes controlling haploid induction(HI)in maize,exhibiting a synergistic ***,it is unknown whether knock out of ZmDMP orthologs can stimulate HI in *** this study,a ZmPLA1 ortholog(OsPLA1)and two ZmDMP orthologs(OsDMP3 and OsDMP6)were identified in *** three genes encode plasma membrane-localized proteins and were highly expressed in mature *** of OsPLA1 in both Minghui 63 and Nipponbare resulted in reduced seed setting rate(SSR)and caused *** osdmp3,osdmp6 and the double mutant failed to trigger HI independently,nor increased the haploid induction rate(HIR)when combined with *** pollinations operations of QX654A with the ospla1 mutant significantly improve SSR,while reducing ***-seq profiling of mature ospla1 mutant anthers indicated that a large number of differentially expressed genes(DEGs)were enriched in redox homeostasis and lipid metabolic GO terms,plant hormone signal transduction,and MAPK signaling *** findings provide important insights towards construction of an efficient DH breeding technology and study of the molecular mechanism of HI in rice.

关键词： Doubled haploid breeding Haploid induction Mutation anlaysis Rice

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The Effect and Mechanism of Fructus lycii on Improvement of Exercise Fatigue Using a Network Pharmacological Approach with in vitro Experimental Verification

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Biomedical and Environmental Sciences 2024年第1期37卷 42-53页

作者： JI Xiao Ning LIU Zhao Ping ZHANG Chao Zheng CHEN Min LIANG Jiang LU Jiang ZHANG Lei national Resource center for Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China China national center for Food Safety Risk Assessment Beijing 100022China Chinese center for Disease Control and Prevention Beijing 102206China

Objective This study aimed to investigate the effect and underlying mechanism of Fructus lycii in improving exercise *** A network pharmacological approach was used to explore potential mechanisms of action of Fructus *** muscle C2C12 cells and immunofluorescence were employed to verify the effect and mechanism of the representative components in Fructus lycii predicted by network pharmacological *** Six potential active components,namely quercetin,β-sitosterol,stigmasterol,7-Omethylluteolin-6-C-beta-glucoside_qt,atropine,and glycitein,were identified to have potency in improving exercise fatigue via multiple pathways,such as the PI3K-Akt,neuroactive ligand-receptor interaction,IL-17,TNF,and MAPK signaling *** immunofluorescence results indicated that quercetin,a significant active component in Fructus lycii,increased the mean staining area of 2-NBDG,TMRM,and MitoTracker,and decreased the area of CellRox compared to the ***,the protein expression levels of p-38 MAPK,p-MAPK,p-JNK,p-PI3K,and p-AKT markedly increased after quercetin *** Fructus lycii might alleviate exercise fatigue through multiple components and *** these,quercetin appears to improve exercise fatigue by enhancing energy metabolism and reducing oxidative *** PI3K-AKT and MAPK signaling pathways also appear to play a role in this process.

关键词： Fructus lycii Exercise fatigue Network pharmacology

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CATCAM: a 28 nm constant-time alteration TCAM enabling less than 50 ns update latency

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Science China(Information Sciences) 2024年第4期67卷 345-346页

作者： Chenchen DENG Tianzhu XIONG Zhaoshi LI Zhiwei LIU Yao WANG Jianfeng ZHU Jun YANG Shaojun WEI Leibo LIU Beijing national Research center for Information Science and Technology Tsinghua University national ASIC System Engineering center School of Integrated CircuitsSoutheast University School of Integrated Circuits Tsinghua University

Ternary content-addressable memory(TCAM) is an indispensable component of lookup tables in switches or ***, it suffers from expensive and inflexible update operations and cannot fulfill the demand for rule updates in switches enabling software-defined networking(SDN). The main reason is that TCAM stores rules from top to bottom in decreasing order of priority for disambiguation. Updating a TCAM is similar to the insertion sort that takes O(n) time,

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Near-field wideband beam training for ELAA with uniform circular array

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Science China(Information Sciences) 2024年第6期67卷 370-383页

作者： Yuhao CHEN Linglong DAI Department of Electronic Engineering Tsinghua UniversityBeijing National Research Center for Information Science and Technology (BNRist)

Extremely large-scale antenna array(ELAA) at millimeter wave(mmWave) and Terahertz(THz)band has been considered a key technology for combating high attenuation in high-frequency bands in future6G communications. Uniform circular arrays(UCAs) have attracted much attention because of their ability to provide flat beamforming gain at all angles. To realize efficient beamforming, beam training is widely used to acquire channel state information. However, with a large antenna number, the beam training overhead in ELAA systems becomes overwhelming. Moreover, with a large bandwidth, the beam defocus effect severely degrades beam training accuracy. To address these issues, this paper proposes a frequency-dependent focusing(FDF)-based beam training scheme to realize effective beam training in near-field wideband ELAA systems with UCA. Specifically, we first analyze the FDF property of UCA, where signals at different subcarriers can simultaneously focus on different distances. Then, by exploiting the FDF property to search different distances using different subcarriers simultaneously, we design a hierarchical codebook and propose an FDFbased beam training scheme. To reveal the effectiveness of the proposed scheme, we compare its necessary beam training overhead with that of existing schemes. Finally, the simulation results demonstrate that the proposed scheme can achieve accurate beam training in near-field wideband UCA systems with a low beam training overhead.

关键词： extremely large-scale antenna array (ELAA) uniform circular array (UCA) near-field wideband beam training

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Observation of parabolic electron bands on superconductor LaRu2As2

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Chinese Physics B 2024年第7期33卷 70-75页

作者：周兴泰李更潘禄禄陈子超李萌时延昊杨海涛高鸿钧 Beijing national center for Condensed Matter Physics and Institute of Physics Chinese Academy of Sciences School of Physical Sciences University of Chinese Academy of Sciences Hefei national Laboratory

Ru-based superconductor LaRu2As2has been discovered exhibiting the highest critical temperature of ～ 7.8 K among iron-free transition metal pnictides with the ThCr2Si2-type crystal structure. However, microscopic research on this novel superconducting material is still lacking. Here, we utilize scanning tunneling microscopy/spectroscopy to uncover the superconductivity and surface structure of LaRu2As2. Two distinct terminating surfaces are identified on the cleaved crystals, namely, the As surface and the La surface. Atomic missing line defects are observed on the La surface. Both surfaces exhibit a superconducting gap of ～ 1.0 me V. By employing quasiparticle interference techniques, we observe standing wave patterns near the line defects on the La atomic plane. These patterns are attributed to quasiparticle scattering from two electron type parabolic bands.

关键词： superconductivity line defect quasi-particle scattering electron band

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Recent progress in single crystal perovskite X-ray detectors

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Science China(Information Sciences) 2024年第3期67卷 5-19页

作者： Xiao LIU Jun REN Yu-Ang CHEN Xiangshun GENG Dan XIE Tian-Ling REN School of Integrated Circuits Tsinghua University Beijing national Research center for Information Science and Technology (BNRist)

Perovskites have attracted extensive attention as radiation detection material due to their long carrier diffusion length and lifetime, high absorption coefficient, and flexible manufacturing process. Compared with polycrystalline structures, single crystal perovskites improve the performance of optoelectronic devices due to their low defect state density, better photoelectric characteristics, and chemical ***, we review the recent progress of single crystal perovskite X-ray detectors. First, we briefly introduced the basic concepts, detection mechanisms, figure of merits of perovskite X-ray detectors, and the preparation methods of single crystal perovskites. Then, we summarized the significant advancements in single crystal perovskite X-ray detectors in recent times. Finally, we discussed the critical challenges and some practicable solutions for developing high-performance X-ray detectors.

关键词： single crystal perovskites carrier transport radiation detection X-ray detectors X-ray imaging

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Construction and Research Progress of the Chinese Meridian Project in 2022–2023

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空间科学学报 2024年第4期44卷 704-711页

作者： WANG Chi CHEN Zhiqing XU Jiyao national Space Science center Chinese Academy of SciencesBeijing 100190

The Chinese Meridian Project(CMP)is a major national science and technology infrastructure constructed in two *** first phase of the CMP has been operating for more than a solar *** 2022 to 2023,utilizing the monitoring data collected by the CMP,scientists made major breakthroughs in fields of ionosphere,middle and upper atmosphere,and coupling between *** construction of the second phase of the CMP is nearly finished,and the project is expected to operate as a whole in 2025 after national acceptance of the second *** whole project was built in an architecture of so-called“One Chain,Three Networks and Four Focuses”.It is promising to make a three-dimensional observation of the whole solar-terrestrial *** science community is looking forward to the great contribution of the CMP to space weather and space physics research.

关键词： Chinese Meridian Project(CMP) Magnetosphere Ionosphere Middle and upper atmosphere

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