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Aggregate 2023年第5期4卷 1-11页

作者： Norhayati Abu Bakar Nur Nazhifah Yusoff Farah Shahadah Nor Azmi Joseph George Shapter Australian Institute for Bioengineering and nanotechnology University of QueenslandSt LuciaAustralia Institute of Microengineering and nanoelectronics Universiti Kebangsaan MalaysiaBangiMalaysia

Monitoring an infectious disease early using highly sensitive and non-invasive techniques is critical for human ***,the development of surfaceenhanced Raman scattering(SERS)for biological detection ideally fits these medical requirements and is rapidly growing as a powerful diagnostic *** can enhance the Raman signal of the target molecule by more than 106 after the adsorption of the molecule on the plasmonic nanostructured *** review provides an overview of the use of gold and silver nanoparticles in SERS substrate designs,followed by the development of these SERS substrates in severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)detection.

关键词： gold nanostars SARS-CoV-2 SERS silver nanostars

Nickel doped zinc oxide nanoparticles produced by hydrothermal decomposition of nickel-doped zinc hydroxide nitrate

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Particuology 2012年第4期10卷 492-496页

作者： Mohammad Yeganeh Ghotbi Nanomaterials and nanotechnology program Ceramic Engineering DepartmentFaculty of EngineeringMalayer UniversityMalayerIran

Zinc hydroxide nitrate, an anionic exchanger layered material, undoped as well as doped with 2-10% nickel, was synthesized by using a pH-controlled precipitation method. The layered materials were then used to produce the undoped and nickel-doped zinc oxides by hydrothermal-treatment. X-ray diffraction, Fourier transform infrared spectroscopy and scanning electron microscopy confirmed the formation of pure phase undoped and nickel-doped layered materials, as well as the products of the hydrothermal- treated materials, nanostructured zinc oxides. Optical studies of the nanostructured zinc oxides showed a decrease in band gap with increasing content of the doping agent, nicke~.

关键词： NanostructureNickel doped zinc oxideChemical synthesisBand gap

Fast RSA decryption through high-radix scalable Montgomery modular multipliers

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Science China(Information Sciences) 2015年第6期58卷 136-151页

作者： WU Tao LI ShuGuo LIU LiTian Department of Microelectronics and nanoelectronics Tsinghua University Institute of Microelectronics Tsinghua University

This paper improves the quotient-pipelined high radix scalable Montgomery modular multiplier by processing w-bit and k-bit words in carry save form instead of some(w + k)-bit length operands. It directly reduces both the critical path and the area overhead of the original processing elements. Then based on this improved high-radix scalable Montgomery modular multiplier, we propose an efficient hardware architecture for RSA decryption with Chinese Remainder Theorem. With simple configuration logics, the hardware unit works in three modes:(1) scalable modular reduction for precomputation,(2) scalable Montgomery modular multiplication for modular exponentiation, where an approximation method is developed to reduce the expanded result below the modulus, and(3) scalable multiplication for post-processing. Hardware implementation shows that the proposed architecture is optimal with reference to the literature in terms of speed, area, and frequency.A 4096-bit RSA decryption in XC2V6000-6 FPGA can be completed in 11.05 ms with 14041 slices/17409 LUTs,128 16 × 16 multipliers, and 70 kbits of block RAMs. Finally, by the use of Montogmery powering ladder the modular exponentiation unit based on the improved high radix scalable Montgomery modular multiplier can be built resistant to fault and simple power attacks. A 1024-bit modular exponentiation unit with such resistances costs about 255 K NAND2 gates in.18 μm CMOS process, and one full modular exponentiation takes about1.44 ms at 250 MHz.

关键词： RSA high radix scalable Montgomery modular multiplication CRT

Nanoparticles for the treatment of spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1665-1680页

作者： Qiwei Yang Di Lu Jiuping Wu Fuming Liang Huayi Wang Junjie Yang Ganggang Zhang Chen Wang Yanlian Yang Ling Zhu Xinzhi Sun Department of Orthopedic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina CAS Key Laboratory of Standardization and Measurement for nanotechnology CAS Key Laboratory for Biomedical Effects of Nanomaterials and NanosafetyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijingChina University of Chinese Academy of Sciences BeijingChina Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Spinal cord injuries lead to significant loss of motor, sensory, and autonomic functions, presenting major challenges in neural regeneration. Achieving effective therapeutic concentrations at injury sites has been a slow process, partly due to the difficulty of delivering drugs effectively. Nanoparticles, with their targeted delivery capabilities, biocompatibility, and enhanced bioavailability over conventional drugs, are garnering attention for spinal cord injury treatment. This review explores the current mechanisms and shortcomings of existing treatments, highlighting the benefits and progress of nanoparticle-based approaches. We detail nanoparticle delivery methods for spinal cord injury, including local and intravenous injections, oral delivery, and biomaterial-assisted implantation, alongside strategies such as drug loading and surface modification. The discussion extends to how nanoparticles aid in reducing oxidative stress, dampening inflammation, fostering neural regeneration, and promoting angiogenesis. We summarize the use of various types of nanoparticles for treating spinal cord injuries, including metallic, polymeric, protein-based, inorganic non-metallic, and lipid nanoparticles. We also discuss the challenges faced, such as biosafety, effectiveness in humans, precise dosage control, standardization of production and characterization, immune responses, and targeted delivery in vivo. Additionally, we explore future directions, such as improving biosafety, standardizing manufacturing and characterization processes, and advancing human trials. Nanoparticles have shown considerable progress in targeted delivery and enhancing treatment efficacy for spinal cord injuries, presenting significant potential for clinical use and drug development.

关键词： antioxidants axon regeneration biocompatible materials drug carriers nanoparticles nerve regeneration neuroinflammatory diseases neuroprotection spinal cord injury stem cells

Preparation of Palladium Supported on Ferric Oxide Nano-catalysts for Carbon Monoxide Oxidation in Low Temperature

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Nano-Micro Letters 2014年第3期6卷 233-241页

作者： Fagen Wang Yan Xu Kunfeng Zhao Dannong He National Engineering Research Center for nanotechnology

Catalytic property of Pd/Fe2O3 catalysts on carbon monoxide(CO) oxidation at low temperature were investigated in this paper. Both the as-prepared and H2-pretreated Pd/Fe2O3 catalysts show catalytic performances on CO oxidation. The CO was completely converted at 333 K for the as-prepared sample,whereas at 313 K for H2-pretreated Pd/Fe2O3-573 catalyst. The catalytic performance of the Pd/Fe2O3 catalyst decreases with increased calcination temperature. This may be due to the increased crystallinity of the support and decreased metal-support interaction. Progressive deactivation of the catalysts during long-time reaction was associated with the formation of carbonates on the catalyst surface that inhibits CO activation or intermediate transformation.

关键词： Pd/Fe2O3 Carbon monoxide Catalytic oxidation Low temperature

Fabrication and characterization of superconducting RSFQ circuits

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Rare Metals 2019年第10期38卷 899-904页

作者： Gang Li Hao Li Jian-She Liu Wei Chen Tsinghua National Laboratory for Information Science and Technology Institute of MicroelectronicsDepartment of Microelectronics and NanoelectronicsTsinghua University

To meet the specification of the qubits in our laboratory,a 0.4 kA·cm^-2 superconducting rapid single flux quantum(RSFQ) circuit was designed and successfully fabricated with an improved Nb-based self-aligned lift-off *** circuit consists of a single-fluxquantum(SFQ) pulse generator,a Josephson transmission line(JTL) and a T-flip flop(TFF),and it acts as a frequency *** values of the inductors in this circuit were extracted using InductEX and the basic function of this circuit was confirmed using the simulation software WRspice before *** fabrication,the basic parameters of this circuit were measured at ~2.5 K in a Janis He-3 *** work laid the theoretical and experimental basis for the future research on the RSFQqubit control circuits.

关键词： Rapid single flux quantum Frequency divider WRspice InductEX

Polarization independent superconducting nanowire detector with high-detection efficiency

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Rare Metals 2015年第2期34卷 71-76页

作者： He-Yu Yin Han Cai Ri-Sheng Cheng Zheng Xu Zhen-Nan Jiang Jian-She Liu Tie-Fu Li Wei Chen Tsinghua National Laboratory for Information Science and Technology Department of Microelectronics and nanoelectronics Tsinghua University Institute of Microelectronics Tsinghua University

The superconducting nanowire single photon detector（SNSPD） draws much attention because of its attractive performance at ultra violet, visible, and nearinfrared wavelengths, and it can be widespread in quantum information technologies. However, how to increase the absorption which can dramatically increase the quantum efficiency of the SNSPD is still a top research issue. In this study, the effect of incident medium and cavity material on the optical absorptance of cavity-integrated SNSPDs was systematically investigated using finite-element method. The simulation results demonstrate that for photons polarized parallel to nanowire orientation, even though the maximum absorptance of the nanowire is insensitive to cavity material,it does increase when the refractive index of incident medium decreases. For perpendicularly polarized photons, both incident medium and cavity material play significant roles,and the absorptance curves get closer to the parallel case as the refractive index of cavity material increases. Based on these results, two cavity-integrated SNSPDs with frontillumination structure which can enhance the absorptance for both parallel and perpendicular photons are ***, a design to realize polarization-independent SNSPDs with high absorptance is presented.

关键词： Polarization-independent Distributed Braggreflective High-detection efficiency Superconductingnanowire single photon detector

A 1-V 60-μW 85-dB dynamic range continuous-time third-order sigma-delta modulator

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Journal of Semiconductors 2009年第12期30卷 118-122页

作者：李渊文齐达董一枫许俊任俊彦 State Key Laboratory of ASIC & System Micro-nanoelectronics Science and Technology Innovation Platform Fudan University

A 1-V third order one-bit continuous-time（CT） EA modulator is presented. Designed in the SMIC mixedsignal 0.13-μm CMOS process, the modulator utilizes active RC integrators to implement the loop filter. An efficient circuit design methodology for the CT ZA modulator is proposed and verified. Low power dissipation is achieved through the use of two-stage class A/AB amplifiers. The presented modulator achieves 81.4-dB SNDR and 85-dB dynamic range in a 20-kHz bandwidth with an over sampling ratio of 128. The total power consumption of the modulator is only 60 μW from a 1-V power supply and the prototype occupies an active area of 0.12 mm^2.

关键词： analog-to-digital converter continuous-time filter low-power low-voltage sigma-delta modulation

Thermoelectric properties of Al-doped ZnO: experiment and simulation

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Journal of Semiconductors 2016年第9期37卷 18-25页

作者： S.Jantrasee P.Moontragoon S.Pinitsoontorn Materials Science and nanotechnology program Faculty of Science Khon Kaen University Department of Physics Faculty of Science Khon Kaen University

Advancement in doping other elements,such as Ce,Dy,Ni,Sb,In and Ga in ZnO^（[1]）,have stimulated great interest for high-temperature thermoelectric *** this work,the effects of Al-doping in a ZnO system on the electronic structure and thermoelectric properties are presented,by experiment and *** powders of Zn_（1-x）Al_xO（x=0,0.01,0.02,0.03 and 0.06） were synthesized by hydrothermal *** XRD results,all samples contain ZnO as the main phase and ZnAl_2O_4（spinel phase） peaks were visible when Al additive concentrations were just 6 at%.The shape of the samples changed and the particle size decreased with increasing Al *** coefficients,on the other hand,did not vary *** were negative and the absolute values increased with ***,the electrical resistivity decreased significantly for higher Al *** electronic structure calculations were carried out using the open-source software package which is based on DFT The energy band gap,density of states of Al-doped ZnO were investigated using PAW pseudopotential method within the LDA ＋ *** calculated density of states was then used in combination with the Boltzmann transport equation^（[3]） to calculate the thermoelectric parameters of Al-doped *** electronic band structures showed that the position of the Fermi level of the doped sample was shifted upwards in comparison to the undoped *** doping Al in ZnO,the energy band gap was decreased,Seebeck coefficient and electrical conductivity were ***,the calculated results were compared with the experimental *** good agreement of thermoelectric properties between the calculation and the experimental results were obtained.

关键词： ZnO doping thermoelectric property

Superconducting Nanowire Single Photon Detector with Optical Cavity

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Chinese Physics Letters 2016年第8期33卷 143-145页

作者：刘杰张立群蒋振南 Kamal Ahmad 刘建设陈炜 Tsinghua National Laboratory for Information Science and Technology Department of Microelectronics and NanoelectronicsInstitute of MicroelectronicsTsinghua University

Increasing the detection efficiency （DE） is a hot issue in the development of the superconducting nanowire single photon detector （SNSPD）. In this work, a cavity-integrated structure coupled to the SNSPD is used to enhance the light absorption of nanowire. Ultra-thin Nb films are successfully prepared by magnetron sputtering, which are used to fabricate Nb/Al SNSPD with the curve of lOOnm and the square area of 4 × 4μm2 by sputtering and the lift-off method. To characterize the optical and electrical performance of the cavity-integrated SNSPD, a reliable cryogenic research system is built up based on a He3 system. To satisfy the need of light coupling, a packaging structure with collimator is conducted. Both DE and the dark count rates increase with lb. It is also found that the DE of SNSPD with cavities can be up to 0.17% at the temperature of 0.7K under the infrared light of 1550nm, which is obviously higher than that of the SNSPD directly fabricated upon silicon without any cavity structure.

关键词： of on with Superconducting Nanowire Single Photon Detector with Optical Cavity DBR DE in is been that