检索结果-南通市图书馆

Metabolic Changes during Acclimation and Hardening to Heat and Drought Stress in <i>Zaprionus indianus</i>

Advances in Entomology 2022年第1期10卷 110-133页

作者： Aditya Moktan Tamang Ravi Parkash Raj Kamal Srivastava Padmasana Singh Department of Zoology Indira Gandhi National Tribal University Amarkantak India Department of genetics Maharshi Dayanand University Rohtak India

The survival ability of insects can be limited with the changes in the levels of energy metabolites under stressful conditions but only a few studies have considered the plastic effects of heat and related climatic factors relevant to tropical habitats. The objectives of our study were to determine whether adults of Zaprionus indianus are capable of rapid heat hardening (RHH) and rapid desiccation hardening (RDH) and to compare its benefits with heat acclimation (HA) and desiccation acclimation (DA). Adult flies reared under season-specific simulated conditions were subjected to 38°C for RHH and 32°C for HA, while 5% relative humidity (RH) was maintained for RDH and 40% RH for DA. Stress-induced effects of heat and desiccation on the levels of five metabolites namely cuticular lipids (CL), total body lipids (TBL), protein, proline, and carbohydrates were then estimated by biochemical method. Different duration of heat hardening and acclimation led to more accumulation of CL whereas different durations of desiccation hardening and acclimation revealed less accumulation. In contrast, there was an accumulation of carbohydrates and protein under desiccation hardening and acclimation whereas there was the utilization of carbohydrates and protein under heat hardening and acclimation. However, mixed results were observed on the level of proline and TBL under both heat and desiccation stress. These stress-triggered changes in the levels of various metabolites suggest a possible link between heat and desiccation tolerance. Hence, these compensatory changes in the level of various metabolit

关键词： Zaprionus indianus Rapid Heat Hardening Heat Acclimation Rapid Desiccation Hardening Desiccation Acclimation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Apert’s syndrome:Study by whole exome sequencing

引用

Genes & Diseases 2018年第2期5卷 119-122页

作者： Anjana Munshi Preeti Khetarpal Satrupa Das Venkateshwar Rao Monica Valecha Manita Bansal Roshan Kumar Centre for Human genetics and Molecular Medicine School of Health SciencesCentral University of PunjabBathindaPunjabIndia Institute of genetics and Hospital for Genetic Diseases Osmania UniversityBegumpetHyderabadIndia Dr.NTR University of Health Sciences VijayawadaAndhra PradeshIndia Positive Bioscience ltd. MumbaiIndia Dept.of Paediatrics Civil HospitalBathindaPunjabIndia

In the present study we attempted a parente-child trio,whole exome sequencing(WES)approach to study Apert’s *** characteristics of the child were noted down and WES was carried out using Ion Torrent System that revealed the presence of previously reported P253R mutation in FGFR2 *** of two SNPs rs1047057 and rs554851880 in FGFR2 gene with an allelic frequency of 0.5113 and 0.001176 respectively and 161 complete damaging mutations were *** study is the first reported case of exome sequencing approach on an Apert’s syndrome patient aimed at providing better genetic counselling in a non-consanguineous relationship.

关键词： Apert syndrome Craniosynostosis Exome sequencing FGFR2 gene Parente-child trio study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Improved Specificity for Breast Cancer Screening Using an Oncogenic(miRNA-21)and a Gene Suppressor(miRNA-195)miRNA in the Serum for a Point of Care(POC)Screening Solution

引用

Biomedical and Environmental Sciences 2023年第6期36卷 549-552页

作者： Krishnamoorthy Kokilavani Ancy Terryna Chanayiltharayil John Bindu Salim Madhulika Vijayakumar Sankar Ganesh Jeyaraj PSG Institute of Advanced Studies Avinashi RoadPeelameduCoimbatore641004 PSG Institute of Medical Science and Research Avinashi Road PeelameduCoimbatore641004 PSG Center for Molecular Medicine and Therapeutics PSG Institute of Medical Sciences and ResearchCoimbatoreTamil Nadu641004India PSG Centre for genetics and Molecular Biology Off Avinashi RoadPeelameduCoimbatoreTamil Nadu641004India

The overall incidence and burden caused by breast cancer is increasing,affecting the global socio-economic development and life expectancy[1].According to“WHO Global Breast Cancer Initiative(GBCI)reports”,if the mortality rate due to breast cancer can be reduced by 2.4%annually,we may prevent 2.5 million breast cancer deaths between2020-2040.

关键词： Breast Cancer Serum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antixenosis and Tolerance of Rice Genotypes Against Brown Planthopper

引用

Rice science 2016年第2期23卷 96-103页

作者： Preetinder Singh SARAO Jagadaish Sanmallappa BENTUR Rice Section Department of Plant Breeding and Genetics Punjab Agricultural University Ludhiana 141004 India indian Institute of Rice Research Hyderabad 500030 India

Nine genotypes were evaluated under greenhouse conditions for antixenosis and tolerance against brown planthopper （BPH, Nilaparvata lugens Stal）. In antixenosis studies, proportion of insects settled on a test genotype in relation to the susceptible control TN1 was recorded, with significantly lower proportion of nymphs （55.22%-59.18%）, adult males （60.33%-60.75%）, and adult females （80.56%- 79.26%） settled on RP2068-18-3-5 and Ptb33 in relation to those on TN1. Based on number of feeding sites, the test genotypes were ranked in order from the highest to the lowest as RP2068-18-3-5, Ptb33, MR1523, Rathu Heenati, Sinnasivappu, ARC10550, MO1, INRC3021 and TNI. The order was exactly reverse in terms of fecundity expressed as number of eggs laid per female. In tolerance studies, days to wilt, functional plant loss index and plant dry weight loss to BPH dry weight produced were recorded. RP2068-18-3-5, Rathu Heenati and Ptb33 performed better than the other test genotypes. These results helped in relative quantification of BPH resistance levels in the genotypes. RP2068-18-3-5, a new effective source of BPH resistance, can be used in resistance breeding after tagging of resistant genes/QTLs linked to different parameters of antixenosis and tolerance with selectable molecular markers.

关键词： antixenosis molecular marker Nilaparvata lugens resistance breeding rice tolerance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improvement of three popular indian groundnut varieties for foliar disease resistance and high oleic acid using SSR markers and SNP array in marker-assisted backcrossing

引用

The Crop Journal 2020年第1期8卷 1-15页

作者： Yaduru Shasidhar Murali T.Variath Manish K.Vishwakarma Surendra S.Manohar Sunil S.Gangurde Manda Sriswathi Hari Kishan Sudini Keshavji L.Dobariya Sandip K.Bera Thankappan Radhakrishnan Manish K.Pandey Pasupuleti Janila Rajeev K.Varshney International Crops Research Institute for the Semi-Arid Tropics(ICRISAT) HyderabadIndia Department of genetics Osmania UniversityHyderabadIndia Junagadh Agricultural University JunagadhIndia ICAR-Directorate of Groundnut Research JunagadhIndia

Foliar fungal diseases(rust and late leaf spot)incur large yield losses,in addition to the deterioration of fodder quality in groundnut *** oleic acid has emerged as a key market trait in groundnut,as it increases the shelf life of the produce/products in addition to providing health benefits to ***-assisted backcrossing(MABC)is the most successful approach to introgressing or pyramiding one or more traits using traitlinked *** used MABC to improve three popular indian cultivars(GJG 9,GG 20,and GJGHPS 1)for foliar disease resistance(FDR)and high oleic acid content.A total of 22 BC3F4 and 30 BC2F4 introgression lines(ILs)for FDR and 46 BC3F4 and 41 BC2F4 ILs for high oleic acid were *** parent genome analysis using the 58 K Axiom_Arachis array identified several lines showing upto 94%of genome recovery among second and third backcross *** of these ILs revealed FDR scores comparable to the resistant parent,GPBD 4,and ILs with high(~80%)oleic acid in addition to high genome *** ILs provide further opportunities for pyramiding FDR and high oleic acid in all three genetic backgrounds as well as for conducting multi-location yield trials for further evaluation and release for cultivation in target regions of india.

关键词： Foliar disease resistance High oleic acid Late leaf spot Marker-assisted backcrossing SNP array Background genome recovery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Biochemical investigations during in vitro adventitious shoot regeneration in leaflet explants from nodal segments of a mature Albizia procera tree

引用

Journal of Forestry Research 2016年第3期27卷 699-705页

作者： Ekta Rai Sulochna Bouddha Shamim Akhtar Ansari genetics and Plant Propagation Division Tropical Forest Research Institute Jabalpur 482021 India Institute of Forest Productivity Lalgutwa Ranchi 835303India

The in vitro adventitious shoot differentiation in leaflet explants of an adult tree differed from that of leaflet explants of seedlings of Albizia procera（Roxb.）Benth. reported previously elsewhere. The leaflet explants from an adult tree passed through an initial callus phase for30 days on MS medium supplemented with 3 % sucrose,2.5 l M 2,4-D followed by a subsequent adventitious shoot differentiation phase for another 30 days on half MS medium supplemented with 0.25 l M each of BA and *** regeneration rate of in vitro adventitious shoots in explants from the adult tree, i.e.1.66 shoots/callus, was lower than that from seedlings, i.e. [10 shoots/callus,which was reported elsewhere. Correspondingly, the activities of nitrate reductase and peroxidase, and endogenous phenol content remained very low during in vitro adventitious shoot differentiation in leaflet explants of an adult tree possibly due to lower availability of competent stem（juvenile） cells for the process.

关键词： Adventitious shoot differentiation Nitratereductase activity Peroxidase activity Phenol Solublesugar

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insight into the liver dysfunction in COVID-19 patients: Molecular mechanisms and possible therapeutic strategies

引用

World Journal of Gastroenterology 2023年第14期29卷 2064-2077页

作者： Naina Khullar Jasvinder Singh Bhatti Satwinder Singh Bhawana Thukral P Hemachandra Reddy Gurjit Kaur Bhatti Department of Zoology Mata Gujri CollegeFatehgarh Sahib 140407PunjabIndia Laboratory of Translational Medicine and Nanotherapeutics Department of Human Genetics and Molecular MedicineSchool of Health SciencesCentral University of PunjabBathinda 151401PunjabIndia Department of Computer Science and Technology Central University of PunjabBathinda 151401PunjabIndia Department of Nutrition and Dietetics University Institute of Applied Health SciencesChandigarh UniversityMohali 140413PunjabIndia Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTX 79430United States Department of Medical Lab Technology University Institute of Applied Health SciencesChandigarh UniversityMohali 140413PunjabIndia

As of June 2022,more than 530 million people worldwide have become ill with coronavirus disease 2019(COVID-19).Although COVID-19 is most commonly associated with respiratory distress(severe acute respiratory syndrome),metaanalysis have indicated that liver dysfunction also occurs in patients with severe *** studies revealed distinctive patterning in the receptors on the hepatic cells that helps in viral invasion through the expression of angiotensinconverting enzyme *** has also been reported that in some patients with COVID-19,therapeutic strategies,including repurposed drugs(mitifovir,lopinavir/ritonavir,tocilizumab,etc.)triggered liver injury and cholestatic *** proven indicators support cytokine storm-induced hepatic *** there are 1.5 billion patients with chronic liver disease worldwide,it becomes imperative to critically evaluate the molecular mechanisms concerning hepatotropism of COVID-19 and identify new potential *** review also designated a comprehensive outlook of comorbidities and the impact of lifestyle and genetics in managing patients with COVID-19.

关键词： COVID-19 Liver damage Pharmacotherapy Cytokine storm Molecular mechanisms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessment of SNP and InDel Variations Among Rice Lines of Tulaipanji x Ranjit

引用

Rice science 2017年第6期24卷 336-348页

作者： Subhas Chandra ROY Vijaya Bhasker REDDY LACHAGARI Plant genetics & Molecular Breeding Laboratory Department of Botany University of North Bengal Siliguri 734013 India AgriGenome Labs Private Limited Hyderabad 500078 India

Genotyping by sequencing(GBS) is the recent approach of next-generation sequencing technique for discovering and genotyping single nucleotide polymorphisms(SNPs) in crop species. Genotypic variation studies(SNPs and insertion-deletions/In Dels) were performed using four rice lines based on GBS data by aligning to the reference genome Nipponbare. Local aromatic rice landrace Tulaipanji was crossed with Ranjit, and two distinct lines were identified from the progenies: one line with awns and aroma traits and the other without awns and aroma. Total number of SNPs and In Dels identified were 52 810 and 4 327 at read depth 10, respectively. Out of the total polymorphic SNPs/In Dels, 16 490 were intergeneric, 7 812 were inside gene, and 4 435 were intronic. Phylogenetically, Tulaipanji was closer to the reference genome nipponbare. Based on recurrent parent genome analysis, out of 10 013 alleles, 92.52% was introgressed into progeny-awn from Tulaipanji and 7.48% from Ranjit, whereas progeny-awnless carried 89.19% alleles from Ranjit and only 10.81% alleles from Tulaipanji. In addition, progeny-awn was the highest heterozygous(83.88%) and progeny-awnless was the least(2.24%) at this fifth generation of recombinant inbred lines. These SNP variations may be linked to the phenotypic traits and can be utilized in crop improvement through linkage mapping. These results suggest that adding a high density of SNP markers to a mapping or breeding population through GBS has a great value for numerous applications in rice breeding and genetics research.

关键词： rice genotyping by sequencing insertion-deletion genomic introgression single nucleotide polymorphism awn aroma heterozygous

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Variation in Antioxidants, Bioactive Compounds and Antioxidant Capacity in Germinated and Ungerminated Grains of Ten Rice Cultivars

引用

Rice science 2017年第6期24卷 349-359页

作者： Maninder KAUR Bavita ASTHIR Gulshan MAHAJAN Department of Biochemistry Punjab Agricultural University Ludhiana Punjab 141004 India Department of Plant Breeding and genetics Punjab Agricultural University Ludhiana Punjab 141004 India

Present study was conducted to characterise ten rice(Oryza sativa L.) cultivars viz. IET-23466, Dhan-201, IET-23448, MAS-946, IET-23445, IET-23463, IET-23455, PR-123, PR-115 and IET-23449 based on antioxidants(total phenolics, flavonols and tannins), bioactive compounds(phytic acid, gamma amino butyric acid, tocopherol and reduced ascorbate) and antioxidant activity(1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, hydroxyl radical scavenging activity, free radical antioxidant power and total reducing power) with an aim to identify cultivars containing higher health promoting components after germination. Three cultivars IET-23466, IET-23463 and PR-123 performed better as revealed by higher level of antioxidants, bioactive compounds and antioxidant activity before and after germination. Three cultivars MAS-946, IET-23445 and IET-23449 had moderate level of antioxidants, bioactive compounds and antioxidant activity. Four cultivars Dhan-201, IET-23448, IET-23455 and PR-115 performed intermediately. Strong positive correlation was observed among total phenolics and the antioxidant activity. Phytic acid was found to be negatively correlated to the antioxidant activity. Our results highlighted that cultivars IET-23466, IET-23463 and PR-123 hold great potential after germination and would open up a useful opportunity for the functional food industry, and consumption of these cultivars after germination would afford health benefits to consumers since they contain higher level of antioxidants.

关键词： antioxidant activity bioactive compound flavonol phytic acid total phenolic rice germination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Correlation between KCNQ1 and KCNJ11 gene polymorphisms and type 2 and posttransplant diabetes mellitus in the Asian indian population

引用

Genes & Diseases 2015年第3期2卷 276-282页

作者： Imran Ali Khan Kiran Kumar Vattam Parveen Jahan Kamal Kiran Mukkavali Qurratulain Hasan Pragna Rao Department of genetics and Molecular Medicine Kamineni HospitalsHyderabadIndia Department of genetics Vasavi Medical and Research CentreKhairathabadHyderabadIndia Department of genetics and Biotechnology Osmania UniversityTarnakaHyderabadIndia Department of Nephrology Kamineni HospitalsHyderabadIndia Department of Biochemistry Kasturba Medical CollegeManipal UniversityManipalKarnatakaIndia

Type 2 diabetes mellitus(T2DM)and post-transplant diabetes mellitus(PTDM)share a common ***,diabetes mellitus is a complex disease,and T2DM and PTDM have different etiologies.T2DM is a metabolic disorder,characterized by persistent hyperglycemia,whereas PTDM is a condition of abnormal glucose tolerance,with variable onset after organ *** KCNQ1 and KCNJ11 gene encode potassium channels,which mediate insulin secretion from pancreatic b-cells,and KCN gene mutations are correlated with the development of ***,no studies have been carried out to establish an association between KCNQ1 and KCNJ11 gene polymorphisms and T2DM and ***,our study was aimed at the identification of the role of KCNQ1 and KCNJ11 gene polymorphisms associated with T2DM and the risk of developing PTDM in the Asian indian *** have carried out a caseecontrol study including 250 patients with T2DM,250 control subjects,42 patients with PTDM and 98 subjects with ***-RFLP analysis was carried out following the isolation of genomic DNA from EDTA-blood *** results of the present study reveal that two single nucleotide polymorphisms(rs2283228 and rs5210,of the KCNQ1 and KCNJ11 genes,respectively)are associated with both T2DM and *** results of our study suggest a role of KCNQ1 and KCNJ11 gene variants in the increased risk of T2DM and PTDM in the Asian indian population.

关键词： Asian indians KCNJ11 KCNQ1 PTDM T2DM

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：