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Journal of Sport and Health Science 2024年第3期13卷 368-372页

作者： Weimo Zhu Wenguang Geng Lingling Huang Xiong Qin Zezhao Chen Hai Yan Yunnan Plateau Thermal Health Industry Innovation Research Institute Tengchong 679100China Department of Kinesiology&Community Health University of Illinois at Urbana-ChampaignUrbanaIL 61801USA Department of Physical Education Nanjing Agricultural UniversityNanjing 210095China School of sports Engineering Beijing Sport UniversityBeijing 100084China School of Strength and Conditioning Training Beijing Sport UniversityBeijing 100084China

Benefits of exercise for personal health,as well as preventing and treating chronic diseases,have been well documented during the past several decades.1 Exercise prescription is a specialized field that involves assessing an individual’s health status,fitness level,and specific goals to create a tailored exercise program based often on the FITT-VP principle.

关键词： prescription diseases assessing

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筋膜是手法治疗耦合应答的“传感器”

Journal of Acupuncture and Tuina Science 2024年第1期22卷 81-90页

作者：程露露王思雨吴庆港陈朝晖 College of Acupuncture and Tuina Anhui University of Chinese MedicineHefei 230012China Graduate School Wuhan Sports UniversityWuhan 430079China College of Chemistry and Bioengineering Guilin University of TechnologyGuilin 541004China

筋膜作为手法力学刺激的初始应答部位,也是手法的效应靶点。手法以“力”为本质特征,其机械力学刺激在筋膜如何转导为神经电信号和生物化学信号,筋膜的理化信号如何启动力学刺激效应,是手法作用原理研究中的共性关键性问题。手法引起筋... 详细信息

筋膜作为手法力学刺激的初始应答部位,也是手法的效应靶点。手法以“力”为本质特征,其机械力学刺激在筋膜如何转导为神经电信号和生物化学信号,筋膜的理化信号如何启动力学刺激效应,是手法作用原理研究中的共性关键性问题。手法引起筋膜结缔组织物理变化,如筋膜组织的形变位移等,可作用于筋膜层神经末梢感受器,产生神经电信号;也可激活筋膜细胞膜上的力学感受器,经机械敏感性离子通道转导将力学信号转化为化学信号,触发筋膜微环境理化耦合应答,通过神经-内分泌-免疫系统途径产生力学刺激效应。“手法机械力”在筋膜通过循经感传,促进机体感知并传递力学刺激信号,表明筋膜是手法力学刺激物理化学信息耦合应答的“传感器”。

关键词：推拿按摩手法治疗筋膜应力,物理机械敏感性离子通道感觉器官

Harnessing cytokine-induced killer cells to accelerate diabetic wound healing:an approach to regulating post-traumatic inflammation

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Regenerative Biomaterials 2024年第2期3卷 88-99页

作者： Yixi Yang Cheng Zhang Yuan Jiang Yijun He iawei Cai Lin Liang Zhaohuan Chen Sicheng Pan Chu Hua Keke Wu Le Wang Zhiyong Zhang Translational Research Centre of Regenerative Medicine and 3D Printing of Guangzhou Medical University Guangdong Province Engineering Research Center for Biomedical EngineeringState Key Laboratory of Respiratory DiseaseDepartment of Orthopaedic SurgeryMedical Technology and Related Equipment Research for Spinal Injury TreatmentCity Key LaboratoryThe Third Affliated Hospital of Guangzhou Medical UniversitySchool of Biomedical EngineeringGuangzhou MedicalUniversityGuangzhouGuangdong510150P.R.China Department of Osteoarthropathy and sports Medicine Panyu Central HospitalGuangzhou 511400P.R.China

Impaired immunohomeostasis in diabetic wounds prolongs infiammation and cytokine dysfunction,thus,delaying or pre-venting wound-surface *** clinical studies have been conducted on cytokine-induced killer(CIK)cells recently,as they can be easily proliferated using a straightforward,inex-pensive ***,the function of CIK cells in regulat-ing inflammatory environments has been drawing attention for clinical *** the current investigation,we discovered the regenerative capacity of these cells in the chal-lenging environment of wounds that heal poorly due to *** demonstrated that the intravenous injection of CIK cells can re-establish a proregenerative inflammatory *** *** accelerateskin healing in diabetic *** results indicated that CIK cell treatment affects macrophage polarization and restores the function regenerative cells under hyperglycemic *** novel cellular therapy offers a promising intervention for clinical applic tions through specific inflammatory regulation functions.

关键词： macrophage diabetic wound post-traumatic inflammation cytokine-induced killer cells vascularization

Microalgae-based drug delivery system for tumor microenvironment photo-modulating and synergistic chemo-photodynamic therapy of osteosarcoma

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Engineered Regeneration 2024年第2期5卷 199-209页

作者： Feng Liang Xueying An Ruoxi Wang Wenshu Wu Lin Yang Yixin Zheng Qing Jiang Xingquan Xu Danni Zhong Min Zhou Eye Center The Second Affiliated HospitalZhejiang University School of MedicineHangzhou310000PR China Department of Orthopedics The First Affiliated HospitalZhejiang University School of MedicineHangzhou310000PR China State Key Laboratory of Pharmaceutical Biotechnology Division of Sports Medicine and Adult Reconstructive SurgeryDepartment of Orthopedic SurgeryNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing210008PR China Zhejiang University-University of Edinburgh Institute(ZJU-UoE Institute) Zhejiang University School of MedicineZhejiang UniversityHaining314400PR China State Key Laboratory of Pharmaceutical Biotechnology Division of Sports Medicine and Adult Reconstructive SurgeryDepartment of Orthopedic SurgeryNanjing Drum Tower HospitalClinical College of Nanjing Medical UniversityNanjing210008PR China Institute of Translational Medicine Zhejiang UniversityHangzhou310029PR China Zhejiang University-Ordos City Etuoke Banner Joint Research Center Zhejiang UniversityHaining314400PR China

Osteosarcoma(OS)is one of the most common malignant tumors in children and young *** chemotherapy and other therapies are limited by low therapeutic efficiency,severe side effects and single therapeutic function,it is of high value to develop innovative therapies for precise and efficient treatment of ***,natural photo-synthetic microalgae(***,CV)were utilized as carriers for the chemotherapeutic agent doxorubicin(DOX)to create a multifunctional therapeutic platform(CV@DOX)for the photo-modulation of the tumor microenvi-ronment(TME)and synergistic chemo-photodynamic therapy of ***@DOX exhibited rapid drug release behavior in the acidic TME,improving the efficiency of chemotherapy against tumors and reducing side effects on other normal *** 650 nm laser irradiation,CV@DOX demonstrated the ability to effectively generate oxygen to alleviate tumor hypoxia and utilize the photosensitizing properties of chlorophyll in CV to produce an increased amount of reactive oxygen species(ROS),thereby enhancing photodynamic therapy(PDT).CV@DOX-mediated synergistic chemo-photodynamic therapy demonstrated efficacy in halting tumor progression in an orthotopic osteosarcoma mouse model by promoting tumor cell apoptosis,inhibiting tumor proliferation and ***,chlorophyll-assisted fluorescence imaging enabled monitoring of the distribution of CV@DOX in osteosarcoma after ***,CV@DOX did not cause significant hematological and tissue toxicity,and prevented DOX-induced cardiotoxicity,showing good in vivo ***,this work presents a novel TME-responsive and TME-modulating platform for imaging-guided multimodal osteosar-coma treatment.

关键词： Osteosarcoma Tumor hypoxia Photodynamic Chemotherapy Synergistic therapy

The Role and the Function of Japan Institute of sports Sciences and National Training Center in Japan

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中国体育科技 2009年第1期45卷 30-32页

作者： Kazuya Kasahara Japan Institute of sports Sciences Japan

Gold Medals in Summer Qlympics Measures A 1) Program to develop junior athletes to top level 2) National Training Center 3) National Coach Academy B 1) sports medicine and sciences(JISS) 2) Anti-doping 3) To hold inte... 详细信息

关键词： The Role and the Function of Japan Institute of sports Sciences and National Training Center in Japan

Evaluation of Psychological Changes on Women Following Coordination Exercises: Immediate Effects of Life Kinetik® Implementation

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Open Journal of Therapy and Rehabilitation 2024年第3期12卷 256-262页

作者： Yutaro Hyodo Takumi Jiroumaru Hikaru Kitagawa Yasumasa Oka Junko Ochi Nobuko Shichiri Takamitsu Fujikawa Department of Physical Therapy Bukkyo University Kyoto City Japan Kanazawa Orthopaedic and sports Medicine Clinic Ritto Japan Department of Applied Biology Graduate School of Science and Technology Kyoto Institute of Technology Kyoto City Japan

Objective: This study aimed to evaluate the immediate psychological effects of coordination exercises on women in Japan. Methods: The subjects were 17 adult women (height, 160.1 ± 5.1 cm;weight, 54.3 ± 10.5 kg;age, 57.8 ± 8.3 years) living in the community and attending a fitness club. The subjects performed a coordination exercise called Life Kinetik®. The subjects responded to the Two-Dimensional Mood Scale–Short Term before and after performing 30 minutes of Life Kinetik®. The results were tabulated and four psychological states were calculated (i.e., vitality, stability, pleasure, and arousal). The pre- and post-implementation results were statistically analyzed using a corresponding t-test. Results: Significant differences were found in activation and arousal levels, but not in stability and comfort levels. Conclusion: The coordination exercise, Life Kinetik®, was found to be an exercise program with potential psychological benefits, as it could change women’s psychological condition to active and excited states.

关键词： Psychological State Life Kinetik® Mood Scale

In vivo real-time monitoring delayed administration of M2 macrophages to enhance healing of tendon by NIR-II fluorescence imaging

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Nano Research 2024年第5期17卷 4379-4390页

作者： Yuzhou Chen Mo Chen Chengxuan Yu Huizhu Li Liman Sai Nguyen T.K.Thanh Yueming Wang Yan Wo Jian Zhang Xing Yang Evgenii L.Guryev Andrei V.Zvyagin Hao De Min Tang Shiyi Chen Yunxia Li Yuefeng Hao Sijia Feng Jun Chen sports Medicine Institute of Fudan University Department of Sports MedicineHuashan HospitalFudan UniversityShanghai 200040China Department of Orthopedic Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Bone and Joint Surgery Department of OrthopedicsRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200001China Department of Physics Shanghai Normal UniversityShanghai 200234China Biophysics Group Department of Physics and AstronomyUniversity College LondonLondon WC1E 6BTUK UCL Healthcare Biomagnetic and Nanomaterials Laboratories London W1S 4BSUK Department of Anatomy and Physiology School of MedicineShanghai Jiao Tong UniversityShanghai 200025China Department of Orthopedics Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou 215500China Institute of Biology and Biomedicine Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Mathematical Institute University of OxfordOxford OX26GGUK Institute of Natural Sciences School of MathematicsShanghai Jiao Tong UniversityShanghai 200240China

The administration time is a critical but long-neglected point in cell therapy based on macrophages because the incorrect time of macrophage administration could result in diverse outcomes regarding the same macrophage *** this work,the second near-infrared(NIR-II)fluorescence imaging in vivo tracking of M2 macrophages during a pro-healing therapy in the mice model of rotator cuff injury revealed that the behavior of administrated macrophages was influenced by the timing of their *** delayed cell therapy(DCT)group had a longer retention time of injected M2 macrophages in the repairing tissue than that in the immediate cell therapy(ICT)*** Keller-Segel model and histological analysis further demonstrated that DCT altered the chemotaxis of M2 macrophages and improved the healing outcome of the repaired structure in comparison with *** results offer a possible explanation of previous conflicting results on reparative cell therapy and provoke reconsideration of the timing of these therapies.

关键词： macrophage cell therapy NIR-II in vivo imaging delayed therapy tendon healing

Injury rate,mechanism,and risk factors of hamstring strain injuries in sports:A review of the literature

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Journal of Sport and Health Science 2012年第2期1卷 92-101页

作者： Hui Liu William E.Garrett Claude T.Moorman Bing Yu sports Biomechanics Laboratory College of Human Movement Science Beijing Sport University sports Medicine Center Duke University Center for Human Movement Science The University of North Carolina at Chapel Hill

Hamstring strains are one of most common sports *** purpose of this literature review is to summarize studies on hamstring strain injury rate,mechanism,and risk factors in the last several decades with a focus on the prevention and rehabilitation of this *** injury commonly occurs in sporting events in which high speed sprinting and kicking are frequently performed,such as Australian football. English rugby,American football,and *** science studies have demonstrated that a muscle strain injury occurs due to excessive strain in eccentric contraction instead of force,and that elongation speed and duration of activation before eccentric contraction affect the severity of the *** strain injury is likely to occur during the late swing phase and late stance phase of sprint *** optimum muscle length,lack of muscle flexibility,strength imbalance,insufficient warm-up,fatigue,lower back injury,poor lumbar posture,and increased muscle neural tension have been identified as modifiable risk factors while muscle compositions,age,race,and previous injuries are non-modifiable risk *** theoretical basis of some of these risk factors,however,is lacking,and the results of clinical studies on these risk factors are *** studies are needed to establish the cause-and-effect relationships between those proposed risk factors and the injury.

关键词： Hamstring injury Mechanism Prevention Rehabilitation Sport medicine

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sports Drink Update

中国运动医学杂志 2001年第1期20卷 110-112页

作者： Ellen Coleman Gatorade sports Science Institute

KEY POINTS:1)The ideal fluid replacement beverage is one that tastes good to the athlete, does not cause gastrointestinal discomfort when consumed in large volumes, promotes rapid fluid absorption and maintenance of extracellular fluid volume, and provides energy to working muscles.2)sports drinks containing 6-8 percent carbohydrate maintain circulatory and thermoregulatory function during exercise as well as plain water and provide greater performance benefits than water.3)The small amount of sodium provided by many sports drinks may help maintain fluid and electrolyte balance during prolonged exercise in the heat.4)Flavored, sweetened beverages encourage voluntary fluid consumption, a response that helps ensure adequate fluid intake during exercise in the heat.

关键词： 110 Res sports Drink Update

Teaching of Tuina Manual Techniques in High Occupational sports Colleges

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Journal of Acupuncture and Tuina Science 2009年第2期7卷 120-122页

作者：吉健友崔明黄国琪 Guangzhou sports Occupation and Technology College

Objective： To enhance the teaching quality of the Tuina Manual Techniques in the high occupational sports colleges. Methods： Performed by multiple educational reforms, including rearrangement of the teaching contents based upon the cognition rules, PBL teaching ideas are involved to improve the teaching condition, increase the multimedia and practical teaching, enrich the teaching resources, and revise the examination and evaluation protocol, etc. Results and Conclusion： By various reforms, the students can not only learn the professional skills, and also elevate their abilities in analyzing and solving their problems.

关键词： Tuina Massage Educational Reform Teaching Methods Multimedia