检索结果-南通市图书馆

Corneal collagen cross‑linking epithelium‑on ***‑off:a systematic review and meta‑analysis

Eye and Vision 2021年第6期8卷 338-352页

作者： Francesco D’Oria Antonio Palazón Jorge L.Alio Vissum Innovation c/Cabañal103016 AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezAlicanteSpain Section of Ophthalmology Department of Basic Medical ScienceNeuroscience and Sense OrgansUniversity of BariBariItaly Department of Clinical Medicine Miguel Hernández UniversitySan Juan de AlicanteSpain

Background:The purpose of the study was to determine the advantages and disadvantages of epi-on corneal crosslinking(CXL)techniques compared with standard epi-off ***:We searched MEDLINE and EMBASE for randomized controlled trials(RCTs)and non-randomized studies of interventions(NRSIs)and we evaluated the selected papers according to the Cochrane risk of bias *** considered,as primary outcomes,average Kmax flattening,changes in uncorrected and corrected distance visual acuity(UDVA and CDVA);as secondary outcomes,we considered changes in pachymetry values and endothelial cell density(ECD).We also investigated adverse events related to the treatments and treatment ***-analysis was conducted with a fixed or random-effects model using weighted mean difference(MD)with 95%confidence interval(CI)as the effect ***:A total of 15 studies were included and among these 15 trials,9 were RCTs and 6 were NRSIs,but only 4 studies showed no high risk of bias and were included in this *** analysis revealed significant postoperative differences in CDVA(MD=0.07;95%CI 0.04 to 0.10;P0.05).Epi-on CXL protocol was found to be significantly less prompt to have risks of delay in epithelial healing(P=0.035)and persistent stromal haze(P=0.026).Conclusion:Epi-on CXL is as effective as epi-off *** for a higher significant improvement in CDVA with current epi-on protocols,our meta-analysis demonstrates that epi-on and epi-off CXL have comparable effects on visual,topographic,pachymetric,and endothelial ***-on CXL has clinical advantages in terms of comfort and avoidance of complications as it reduces the risk of developing delay in epithelial healing and persistent stromal haze.

关键词： Corneal collagen cross-linking Keratoconus Transepithelial CXL Epithelium-off CXL Epithelium-on CXL Iontophoresis

来源：

维普期刊数据库

维普期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Getting started in mapping-by-sequencing

引用

Journal of Integrative Plant Biology 2015年第7期57卷 606-612页

作者： Héctor Candela Rubén Casanova-Sáez José Luis Micol Instituto de Bioingeniería Universidad Miguel Hernández Department of Forest Genetics and Plant Physiology Umea Plant Science CenterSwedish University of Agricultural Sciences

Next-generation sequencing （NGS） technologies allow the cost-effective sequencing of whole genomes and have expanded the scope of genomics to novel applications, such as the genome-wide characterization of intraspecific polymorphisms and the rapid mapping and identification of point mutations. Next-generation sequencing platforms, such as the Illumina HiSeq2ooo platform, are now commercially available at affordable prices and routinely produce an enormous amount of sequence data, but their wide use is often hindered by a lack of knowledge on how to manipulateand process the information produced. In this review, we focus on the strategies that are available to geneticists who wish to incorporate these novel approaches into their research but who are not familiar with the necessary bioinformatic concepts and computational tools. In particular, we comprehensively summarize case studies where the use of NGS technologies has led to the identification of point mutations, a strategy that has been dubbed ＂mapping-by-sequencing＇, and review examples from plants and other model species such as Caenorhabditis elegans, Saccharomyces cerevisiae, and Drosophila mela- nogaster. As these technologies are becoming cheaper and more powerful, their use is also expanding to allow mutation identification in species with larger genomes, such as many crop plants.

关键词： Mapping-by-sequencing massively parallel sequencing mutation identification SHOREmapping whole-genome re-sequencing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Retinal image quality with multifocal,EDoF,and accommodative intraocular lenses as studied by pyramidal aberrometry

引用

Eye and Vision 2021年第6期8卷 374-384页

作者： Jorge L.Alio Francesco D’Oria Francesca Toto Joan Balgos Antonio Palazon Francesco Versaci Jorge L.Alio del Barrio Vissum Innovation AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezVissum Miranzac/Cabañal103016 AlicanteSpain Section of Ophthalmology Department of Basic Medical ScienceNeuroscience and Sense OrgansUniversity of BariBariItaly Department of Clinical Medicine Miguel Hernández UniversitySan Juan de AlicanteSpain R&D Department Costruzione Strumenti Oftalmici(CSO)FlorenceItaly

Background:To study and compare the clinical optical image quality following implantation with different premium IOLs by analysing the point spread function(PSF)Strehl ratio using a pyramidal wavefront sensor(PWS)-based ***:This study included 194 eyes implanted with:(a)19 AcrySof SA60AT(control group);(b)19 Miniwell;(c)24 LENTIS Mplus LS-313 MF30;(d)33 LENTIS Mplus LS-313 MF15;(e)17 AkkoLens Lumina;(f)31 AT LISA Tri 839MP;(g)20 Precizon Presbyopic;(h)20 AcrySof IQ PanOptix;(i)11 Tecnis *** outcome measures were PSF Strehl ratio,PSF Strehl ratio excluding second-order aberrations(PSFw2),total root mean square(RMS),low-order aberration(LOA)and high-order aberration(HOA)RMS measured by PWS ***:AT LISA Tri had the highest PSFw2 Strehl ratio at both 3.0-and 4.0-mm pupil size(0.52±0.14 and 0.31±0.10;P<0.05),followed by SA60AT(0.41±0.11 and 0.28±0.07)and PanOptix(0.4±0.07 and 0.26±0.04).AT LISA Tri was found to provide a significantly better retinal image quality than PanOptix at both 3.0 mm(P<0.0001)and 4.0 mm(P=0.004).Mplus MF15 was found to be significantly better than Mplus MF30 at both 3.0 mm(P<0.0001)and 4.0 mm(P=0.002).Total RMS,LOA RMS,HOA RMS,PSF Strehl ratio and PSFw2 varied significantly between the studied groups(P<0.001).Conclusions:Far distance clinical image quality parameters measured by PWS aberrometer differed significantly according to the technology of the implanted *** LISA Tri,SA60AT and PanOptix showed the highest values of far distance retinal image quality,while the lowest PSFw2 Strehl ratios were displayed by Miniwell,Mplus MF30 and Precizon Presbyopic.

关键词： Cataract surgery Pyramidal aberrometry Multifocal IOL Extended depth of focus Accommodative IOL

来源：

维普期刊数据库

维普期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Surgical options for correction of refractive error following cataract surgery

引用

Eye and Vision 2014年第1期1卷 2-8页

作者： Ahmed A Abdelghany Jorge L Alio Clinical research fellow in Vissum Corporación Alicante Universidad Miguel HernándezAlicanteSpain Minia university MiniaEgypt Vissum Corporación AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezAlicanteSpain Avda de Denia s/n Edificio VissumAlicante 03016Spain.

Refractive errors are frequently found following cataract surgery and refractive lens *** biometric analysis,selection and calculation of the adequate intraocular lens(IOL)and modern techniques for cataract surgery all contribute to achieving the goal of cataract surgery as a refractive procedure with no refractive ***,in spite of all these advances,residual refractive error still occasionally occurs after cataract surgery and laser in situ keratomileusis(LASIK)can be considered the most accurate method for its ***-based procedures,such as IOL exchange or piggyback lens implantation are also possible alternatives especially in cases with extreme ametropia,corneal abnormalities,or in situations where excimer laser is *** our review,we have found that piggyback IOL is safer and more accurate than IOL *** aim is to provide a review of the recent literature regarding target refraction and residual refractive error in cataract surgery.

关键词： Cataract surgery Target refraction Residual refractive error Refractive surprise Excimer laser surgery Photorefractive keratectomy Intraocular lens exchange Piggyback lens

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health Seek: A Deep Learning-Based Intelligent System to Aid Medical Diagnosis

引用

Journal of Biomedical Science and Engineering 2022年第1期15卷 66-81页

作者： Manuel López Antonio Peñalver Center of Operations Research Miguel Hernández University Elche Spain

Medical diagnosis is one of the most tedious and complex processes that healthcare personnel face in their day-to-day life. To establish an adequate treatment, it is essential to carry out a correct and early evaluation of each patient. Occasionally, given the number of tests that need to be performed, this evaluation process can require a significant amount of time, and can negatively affect the patient’s recovery. The objective of this work is the development of a new software that, using Artificial Intelligence (AI), offers the healthcare professional support in the process of diagnosing the patient, as well as preventing the probability of suffering a certain disease, based on test information analytics and demographic information available. The system allows storing multiple models based on Deep Learning (DL), previously trained for the diagnosis of different diseases. These models allow predictions to be made based on available medical information. As a use case, one of these models has been successfully tested in diagnosing stroke events.

关键词： Diagnosis Artificial Intelligence Deep Learning Stroke Intelligence Systems

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Areas of research and clinical approaches to the study of liver abscess

引用

World Journal of Gastroenterology 2017年第2期23卷 357-365页

作者： Gregorio González-Alcaide Jorge Peris José Manuel Ramos Department of History of Science and Documentation University of Valencia Deparment of Internal Medicine Hospital Universitario Sant Joan d’Alacant Departament of Clinical Medicine Universidad Miguel Hernández de Elche Department of Internal Medicine Hospital General Universitario de Alicante

AIMTo analyze the research activity on liver abscess (LA) and identify the main topic clusters in the *** identified all documents using the medical subject heading “LA” indexed in the MEDLINE database between 2001 and 2015. We performed a descriptive bibliometric analysis, characterizing the evolution of scientific activity, the publication types of the documents, the document categories of clinical interest (case reports, clinical trials, evaluation studies, meta-analysis, observational studies, practice guidelines and validation studies) and the geographic distribution of the research. We also carried out an analysis of networks and research clusters in order to identify the main topic areas of *** search yielded a total of 1278 documents, showing a stable scientific production over the study period and a marked multidisciplinary nature. The research was dominated by case reports (65.9% of the documents analyzed). In terms of geographic distribution, researchers from the United States led in the number of signatures (n = 229), followed by those from Taiwan (n = 185), India (n = 145), Japan (n = 144), South Korea (n = 100), and China (n = 84). With regard to amebic LA, the top-producing countries were India and Mexico (n = 69 each), followed by the United States (n = 29). In the case of pyogenic LA, Taiwan Residents researchers led scientific production (n = 71), followed by the United States (n = 39) and China (n = 29). The most active areas of research in the field are diagnosis via computerized tomography scan, differential diagnosis with regard to liver cancer, treatment with antimicrobial agents, and Klebsiella infections (including bacteremia).CONCLUSIONClinical case reports associated with diagnosis and treatment are the main topic of study, highlighting the importance of this document type in advancing knowledge.

关键词： Liver abscess Cluster analysis Amebic abscess Pyogenic abscess Bibliometrics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mitigation of Climate Change:Too Little or Too Much

引用

Journal of Geographical Research 2022年第1期5卷 55-56页

作者： Jose Navarro-Pedreño Department of Agrochemistry and Environment University Miguel Hernández of ElcheElche(Alicante)Spain

Professor Emmanuel Epstein gave a conference entitled“Too little or too much”referring to plant nutrition and essential elements in 1990[1],serves this as a tribute to this professor emeritus,and this concept fit well with the actions related to mitigation of Climate *** the 26th UN Climate Change Conference of the Parties[2]held in Glasgow under the slogan“UNITING THE WORLD TO TACKLE CLIMATE CHANGE”,it is time to reflect deeply on the subject and act.

关键词： Glasgow Epstein entitled

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Postural control quantification in minimally and moderately impaired persons with multiple sclerosis:The reliability of a posturographic test and its relationships with functional ability

引用

Journal of Sport and Health Science 2020年第6期9卷 677-684页

作者： David Barbado Ramon Gomez-Illan Pedro Moreno-Navarro Gregori Valero-Conesa Raul Reina Francisco J.Vera-Garcia Department of Sport Sciences Sports Research CentreMiguel Hern_andez University of ElcheElche(Alicante)03202Spain

Background:Postural control has been associated with the functional impairment in persons with multiple sclerosis(pwMS).However,there is a need for reliable methods to assess postural control in early stages of the disease,when subtle changes can be difficult to *** aims of this study were to assess the absolute and relative reliability of a standing and a sitting posturographic protocol in minimally(Expanded Disability Status Scale≤2)and moderately(2.5≤Expanded Disability Status Scale≤4)impaired pwMS,and to analyze relationships among postural control and functional mobility and gait ***:To assess postural control in an upright stance,14 minimally and 16 moderately impaired pwMS performed six 70 s trials in tandem stance,3 with their weaker leg behind(TSWL)and 3 with their stronger leg behind(TSSL).Additionally,participants completed five 70 s trials using an unstable sitting protocol(US)to assess trunk *** mean radial errors of TSWL,TSSL,and US trials were calculated as postural control ***,participants performed the Timed Up and Go test(TUG)and the Timed 25-foot Walk test(T25FW)to measure their functional mobility and gait speed,*** was evaluated using the intraclass correlation coefficient(ICC3,1)and the standard error of measurement(SEM).Analyses of variances were carried out to assess between-group ***’g index(dg)was used to estimate the effect size of *** correlation analyses(r)were performed to examine the relationships among the postural control and the functional ***:Posturographic tests showed a high reliability in both minimally(0.87≤ICC≤0.92;9.32%≤SEM≤11.76%)and moderately(0.80≤ICC≤0.92;10.33%≤SEM≤15.33%)impaired ***,T25FW and TUG displayed a high consistency in minimally(0.89≤ICC≤0.94;3.43%≤SEM≤5.17%)and moderately(0.85≤ICC≤0.93;5.57%≤SEM≤6.56%)impaired *** impaired pwMS showed a better performance on the TUG,T25FW

关键词： Balance Consistency of the assessment Core stability Functional mobility

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Using Landsat Images to Determine Water Storing Capacity in Mediterranean Environments

引用

Journal of Geographical Research 2021年第4期4卷 58-67页

作者： Gema Marco Dos Santos Jose Navarro-Pedreño Ignacio Meléndez-Pastor Ignacio Gómez Lucas Departament of Agrochemistry and Environment University Miguel Hernández of ElcheEdifAlcudiaElche03202Spain

Reservoirs play an important role in water management and are key elements for water *** is needed in order to guarantee the quantity and quality of stored ***,this task is sometimes not *** objective of this study was to develop a procedure for predicting volume of stored water with remote sensing in water bodies under Mediterranean climate *** achieve this objective,multispectral Landsat 7 and 8 images(NASA)were analyzed for the following five reservoirs:La Serena,La Pedrera,Beniarrés,Cubillas and Negratín(Spain).Reservoirs water surface was computed with the spectral angle mapper(SAM)*** that,cross-validation regression models were computed in order to assess the capability of water surface estimations to predict stored water in each of the *** statistical models were trained with Landsat 7 images and were validated by using Landsat 8 *** results suggest a good capability of water volume prediction from free satellite imagery derived from surface water *** free remote sensing images and open source GIS algorithms can be a very useful tool for water management and an integrated and efficient way to control water storage,especially in low accessible sites.

关键词： Climate change Decision-making tools GIS Reservoir Water storage

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reply to the letter to the editor

引用

Eye and Vision 2021年第1期8卷 462-463页

作者： Jorge L.Alio Francesco Versaci Francesco D’Oria Vissum Miranza AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezAlicanteSpain R&D Department Costruzione Strumenti Oftalmici(CSO)FlorenceItaly Section of Ophthalmology Department of Basic Medical ScienceNeuroscience and Sense OrgansUniversity of BariBariItaly

We appreciate the interest of miguel Faria Ribeiro in our paper[1],as well as the comments made to *** interest of the topic is sound,as nowadays an enormous amount of new so-called“premium lenses”are appearing in the market,with different optical profiles which obviously lead to different light distributions and different quality of retinal *** is why our interest in this topic is longstanding and we have published extensive summaries about the outcomes and complications of multifocal lenses over the last years[2,3].

关键词： editor letter enormous

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：