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Patient Safety in the Use of Mechanical Restraints: Regulatory Compliance among Hospitals in the City of Buenos Aires and Proposal for Its Improvement

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Open Journal of Emergency Medicine 2024年第2期12卷 33-39页

作者： Martín Javier Mazzoglio y Nabar Sergio Giordano Edgardo Knopoff Lorena Onofrio Oscar Agustín Porta Romina Rodríguez Emergency Service Torcuato de Alvear Psychiatric Emergency Hospital Buenos Aires Argentina Department of Psychiatry and mental health Faculty of Medicine University of Buenos Aires Buenos Aires Argentina

Introduction: Mechanical or physical restraint is an exceptional therapeutic resource to immobilize a subject and thus guarantee the safety of the patient and/or third parties in the face of high-risk behaviors, but it entails multiple crossings (bioethical, philosophical, medical, psychological, legal). Framed in the so-called “safety culture” developed by the WHO, based on the Protocol for its implementation of the CABA and attentive to its frequent use in CABA by different hospital services (medical clinic, geriatrics, intensive care and medical guards) we consider it necessary its study in terms of compliance with the risks it entails and its management. Objectives: Identify regulatory compliance with the GCABA Mechanical restraint (MR) Protocol from a patient safety perspective, as well as describe the clinical and medicolegal aspects, and propose the usefulness of a tool for its management and control. Methodology: Observational, descriptive, transversal and prospective work through the analysis of Clinical Records with indication of MR using a rubric-type form. 177 cases were analyzed between September-November 2023 from three hospitals of the Government of the City of Buenos Aires, statistical parameters were applied and graphs were made. Results: Only 12.99% complied with the Protocol. In the mental health specialized hospital compliance was almost 5 times greater than in the general one, and in the emergency services compliance was 12 times greater than in Inpatient services. We found that the start or end time of MR was not recorded and only 43% described the causes/justifications for the indication (mostly in Emergency and Specialized hospitals), with the MR average time being shorter in Emergency. Conclusions: Only 1.3 out of 10 patients reliably completed the Protocol and it was mostly in the mental health specialized hospital and the emergency services. The results show non-compliance behavior in the application and management of the risk that the use

关键词： Mechanical Containment Patient Safety Injuries in Custody Buenos Aires City Check List

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Clinical Application and Research Progress of Common Event-Related Potentials

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Medicinal Plant 2024年第4期15卷 80-82页

作者： Keke MA Conghui WANG Xiong CHEN Chunqi AI Graduate School Hubei University of MedicineShiyan 442000China mental health Center Shiyan Taihe Hospital(Affiliated Hospital of Hubei University of Medicine)Shiyan 442000China

This paper review focuses on the diagnostic application and clinical efficacy correlation of event-related potentials,such as P300,MMN,CNV and N400,in patients with depression,and provides a reliable theoretical basis... 详细信息

关键词： Depression Cognitive function EEG biofeedback Research progress

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Navigating emotional challenges:A journey with patients undergoing chemotherapy

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World Journal of Clinical Oncology 2024年第9期15卷 1132-1135页

作者： Nisha Mani Pandey Pooja Ramakant Department of Geriatric mental health King George's Medical UniversityLucknow 226003India Department of Endocrine Surgery King Georges Medical UniversityLucknow 226003India

A recent article reported that cancer patients with subthreshold depression are more likely to develop major depression within a *** regression analysis revealed that regular exercise was a protective factor against cancerrelated fatigue,whereas advanced age,radiotherapy,pain,and low hemoglobin were risk factors for cancer-related fatigue.A limitation of this study was the lack of methodological details about leukemia patients receiving depressive treatment at a specific *** assessment,behavioral modification plans,communication,destressing techniques,and educational plans may help chemotherapy patients manage emotional issues and reduce ***,these strategies can inspire patients to create,facilitate their treatment,and help them to remain healthy.

关键词： Leukemia patients Cancer patients Emotional distress Subthreshold depression Chemotherapy

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Positive Effect of Transcranial Direct Current Stimulation on Visual Verbal Working Memory in Patients with Attention-Deficit/Hyperactivity Disorder

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Open Journal of Psychiatry 2024年第4期14卷 334-346页

作者： Tomoko Uchida Daisuke Matsuzawa Tadashi Shiohama Katsunori Fujii Akihiro Shiina Masamitsu Naka Katsuo Sugita Eiji Shimizu Naoki Shimojo Hiromichi Hamada Department of Pediatrics Graduate School of Medicine Chiba University Chiba Japan Research Center for Child mental Development Chiba University Chiba Japan Division of Medical Care and Treatment Center for Forensic Mental Health Chiba University Chiba Japan Department of Cognitive Behavioral Physiology Graduate School of Medicine Chiba University Chiba Japan

Background: Working memory is an executive function that plays an important role in many aspects of daily life, and its impairment in patients with attention-deficit/hyperactivity disorder (ADHD) affects quality of life. The dorsolateral prefrontal cortex (DLPFC) has been a good target site for transcranial direct current stimulation (tDCS) due to its intense involvement in working memory. In our 2018 study, tDCS improved visual-verbal working memory in healthy subjects. Objective: This study examines the effects of tDCS on ADHD patients, particularly on verbal working memory. Methods: We conducted an experiment involving verbal working memory of two modalities, visual and auditory, and a sustained attention task that could affect working memory in 9 ADHD patients. Active or sham tDCS was applied to the left DLPFC in a single-blind crossover design. Results: tDCS significantly improved the accuracy of visual-verbal working memory. In contrast, tDCS did not affect auditory-verbal working memory and sustained attention. Conclusion: tDCS to the left DLPFC improved visual-verbal working memory in ADHD patients, with important implications for potential ADHD treatments.

关键词： Working Memory Attention-Deficit/Hyperactivity Disorder Dorsolateral Prefrontal Cortex Transcranial Direct Current Stimulation

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Chinese version of the Perth Alexithymia Questionnaire:psychometric properties and clinical applications

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General Psychiatry 2024年第2期37卷 274-283页

作者： Xin-Lu Cai Qingying Ye Ke Ni Lin Zhu Qian Zhang Minmin Yin Zhe Zhang Wei Wei David A.Preece Bao-Ming Li Institute of Brain Science and Department of Physiology School of Basic Medical SciencesHangzhou Normal UniversityHangzhouZhejiangChina Zhejiang Philosophy and Social Science Laboratory for Research in Early Development and Childcare Hangzhou Normal UniversityHangzhouZhejiangChina Qiqihar mental health Center QiqiharChina Department of Special Education Faculty of EducationHangzhou Normal UniversityHangzhouZhejiangChina Department of Neurobiology Affiliated Mental Health Center&Hangzhou Seventh People's Hospital Zhejiang University School of MedicineHangzhouZhejiangChina Liangzhu Laboratory MOE Frontier Science Center for Brain Science and Brain-machine IntegrationState Key Laboratory of Brain-machine IntelligenceZhejiang UniversityHangzhouZhejiangChina NHC and CAMS Key Laboratory of Medical Neurobiology Zhejiang UniversityHangzhouChina School of Population health and Curtin enAble Institute Curtin UniversityPerthWestern AustraliaAustralia School of Psychological ScienceThe University of Western AustraliaPerthWestern AustraliaAustralia

Background The alexithymia trait is of high clinical *** Perth Alexithymia Questionnaire(PAQ)was recently developed to enable detailed facet-level and valence-specific assessments of *** In this paper,we introduce the first Chinese version of the PAQ and examine its psychometric properties and clinical *** In Study 1,the PAQ was administered to 990 Chinese *** examined its factor structure,internal consistency,test-retest reliability,as well as convergent,concurrent and discriminant *** Study 2,four groups,including a major depressive disorder(MDD)group(n=50),a matched healthy control group for MDD(n=50),a subclinical depression group(n=50)and a matched healthy control group for subclinical depression(n=50),were *** comparisons were conducted to assess the clinical relevance of the *** In Study 1,the intended five-factor structure of the PAQ was found to fit the data *** PAQ showed good internal consistency and test-retest reliability,as well as good convergent,concurrent and discriminant *** Study 2,the PAQ was able to successfully distinguish the MDD group and the subclinical depression group from their matched healthy *** The Chinese version of the PAQ is a valid and reliable instrument for comprehensively assessing alexithymia in the general population and adults with clinical/subclinical depression.

关键词： clinical instrument matched

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Predictive value of machine learning models for lymph node metastasis in gastric cancer: A two-center study

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 85-94页

作者： Tong Lu Miao Lu Dong Wu Yuan-Yuan Ding Hao-Nan Liu Tao-Tao Li Da-Qing Song Department of Emergency Medicine Jining No.1 People’s HospitalJining 272000Shandong ProvinceChina Wuxi mental health Center Wuxi 214000Jiangsu ProvinceChina Department of Gastroenterology Jining No.1 People’s HospitalJining 272000Shandong ProvinceChina Department of Oncology The Affiliated Hospital of Xuzhou Medical UniversityXuzhou 221002Jiangsu ProvinceChina

BACKGROUND Gastric cancer is one of the most common malignant tumors in the digestive system,ranking sixth in incidence and fourth in mortality *** 42.5%of metastatic lymph nodes in gastric cancer belong to nodule type and peripheral type,the application of imaging diagnosis is *** To establish models for predicting the risk of lymph node metastasis in gastric cancer patients using machine learning(ML)algorithms and to evaluate their pre-dictive performance in clinical *** Data of a total of 369 patients who underwent radical gastrectomy at the Depart-ment of General Surgery of Affiliated Hospital of Xuzhou Medical University(Xuzhou,China)from March 2016 to November 2019 were collected and retro-spectively analyzed as the training *** addition,data of 123 patients who underwent radical gastrectomy at the Department of General Surgery of Jining First People’s Hospital(Jining,China)were collected and analyzed as the verifi-cation *** ML models,including decision tree,random forest,support vector machine(SVM),gradient boosting machine,naive Bayes,neural network,and logistic regression,were developed to evaluate the occurrence of lymph node metastasis in patients with gastric *** ML models were established fo-llowing ten cross-validation iterations using the training dataset,and subsequently,each model was assessed using the test *** models’performance was evaluated by comparing the area under the receiver operating characteristic curve of each *** Among the seven ML models,except for SVM,the other ones exhibited higher accuracy and reliability,and the influences of various risk factors on the models are *** The ML models developed exhibit strong predictive capabilities for lymph node metastasis in gastric cancer,which can aid in personalized clinical diagnosis and treatment.

关键词： Machine learning Prediction model Gastric cancer Lymph node metastasis

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Suicide Ideation and Its Associated Factors among Men in Selected Compounds of Lusaka, Zambia

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Open Journal of Psychiatry 2024年第4期14卷 300-318页

作者： Musanda Siachinji Kestone Lyambai Jamia Milanzi Levy Mwanawasa University Teaching Hospital Lusaka Zambia Department of mental health and Psychiatry School of Nursing Sciences University of Zambia Lusaka Zambia School of Nursing and Midwifery Mulungushi University Kabwe Zambia

Background: Globally, it is estimated that more than 800,000 individuals die by suicide each year, making suicide one of the biggest causes of death worldwide. Additionally, suicide kills far more males than women, more so in developing regions that are characterized by economic distress due to low income. Although the number of suicide cases has been seen to increase from 2013 to date, limited studies provide information on the factors influencing the trend. Therefore, this study aimed at investigating the prevalence of suicidal ideation and factors associated with suicide in males in selected compounds of Lusaka. Methods: The study used an analytical quantitative cross- sectional study design that involved 367 men in Mtendere and Kaunda Square townships in Lusaka district, Zambia. A structured questionnaire was used to collect data from participants, which was analyzed using Statistical Package for Social Sciences (SPSS) version 26.0. The Chi-square, Fisher’s exact test and Wilcoxon rank sum tests were used to test relationships among variables at a five percent level of significance. Ethical approval and clearance was obtained from the National health Research Authority. Results: Participants had a median age of 29 years (IQR, 27 - 32 years), 216 (58.9%) were single and 278 (75.8%) attained tertiary education. Under a quarter, 75 (20.4%) reported suicide ideations, and 97 (26.4%) reported low social support. For most participants, 347 (94.7%) experienced at least one stressful life event, and 359 (97.8%) experienced severe levels of stress. Under half, 170 (46.3%) were alcohol dependent, while 54 (14.7%) used alcohol harmfully. Suicide ideation was significantly associated with marital status (p Conclusion: Suicide ideation is relatively high among men in Mtendere and Kaunda Square townships, mainly influenced by marital status, education level, social support, stressful events alcohol abuse. Efforts must be channeled towards suicide awareness campaigns, and esta

关键词： Suicide Ideation Social Support Substance Abuse

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The prolactin receptor(PRLR)gene is linked to and associated with the comorbidity of depression and type 2 diabetes in Italian families

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Genes & Diseases 2024年第3期11卷 15-17页

作者： Mutaz Amin Rongling Wu Teodor T.Postolache Claudia Gragnoli INSERM US14-OrphanetParis 75014France University of Paris Paris 75013France Department of Biochemistryand Molecular Biology Faculty of MedicineAl-Neelain UniversityKhartoum 11121Sudan Department of Public health Sciences Penn State College of MedicineHersheyPA 17033USA Department of Statistics Penn State College of MedicineHersheyPA 17033USA Mood and Anxiety Program Department of PsychiatryUniversity of Maryland School of MedicineBaltimoreMD 21201USA Rocky Mountain mental Illness Research Education and Clinical Center(MIRECC) Veterans Integrated Service Network(VISN)19Military and Veteran Microbiome:Consortium for Research and Education(MVM-CoRE)DenverCO80246USA mental illness Research Education and Clinical Center(MIRECC) Veterans Integrated Service Network(VISN)5VA Capitol Health Care NetworkBaltimoreMD 21090USA Division of Endocrinology Department of MedicineCreighton University School of MedicineOmahaNE 68124USA Molecular Biology Laboratory Bios Biotech Multi-Diagnostic Health CenterRome 00197Italy

Major depressive disorder(MDD)and type 2 diabetes(T2D)are two common complex multifactorial disorders that share several genetic and environmental risk factors such as hypercortisolism and related genes'riskvariants within the stress response and the neuroendocrine hypothalamicpituitary *** stress,the pituitary gland releases prolactin(PRL),whose effects are pleiotropic and include mood control and insulin secretion from the beta cells.1 Variations in the prolactin receptor(PRLR)gene are associated in rodent models with stress level,depressionlike behavior,2 and hepatic insulin sensitivity3 and in humans with maternal glucose homeostasis and gestational diabetes.

关键词： diabetes prolactin pituitary

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Contrast-enhanced guided endoscopic ultrasound procedures

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World Journal of Gastroenterology 2024年第17期30卷 2311-2320页

作者： Marcel Ioan Gheorghiu Andrada Seicean Cristina Pojoga Claudia Hagiu Radu Seicean Zeno Sparchez Department of Gastroenterology “Prof.Dr.Octavian Fodor”Regional Institute of Gastroenterology and Hepatology"Iuliu Hatieganu"University of Medicine and PharmacyCluj-Napoca 400162ClujRomania Department of Clinical Psychology and Psychotherapy International Institute for Advanced Study of Psychotherapy and Applied Mental HealthBabeș-Bolyai UniversityCluj-Napoca 400375ClujRomania The First Surgical Clinic "Iuliu Hatieganu"University of Medicine and PharmacyCluj Napoca 400006ClujRomania

Contrast-enhanced endoscopic ultrasound(CH-EUS)can overcome the limi-tations of endoscopic ultrasound-guided acquisition by identifying microvessels inside inhomogeneous tumours and improving the characterization of these *** the initial enthusiasm that oriented needle sampling under CH-EUS guidance could provide better diagnostic yield in pancreatic solid lesions,further studies did not confirm the supplementary values in cases of tissue acquisition guided by *** review details the knowledge based on the available data on contrast-guided *** indications for CH-EUS tissue acquisition include isoechoic EUS lesions with poor visible delineation where CH-EUS can differentiate the lesion vascularisation from the surrounding parenchyma and also the mural nodules within biliopancreatic cystic lesions,which occur in select ***,the roles of CH-EUS-guided therapy in patients whose pancreatic fluid collections or bile ducts that have an echogenic content have indications for drainage,and patients who have nonvisualized vessels that need to be highlighted via Doppler EUS are *** indication is represented if there is a need for an immediate assessment of the post-radiofrequency ablation of pancreatic neuroendocrine tumours,in which case CH-EUS can be used to reveal the incomplete tumour destruction.

关键词： Endosonography Contrast-enhanced endoscopic ultrasound Tissue acquisition Fine needle aspiration Fine needle biopsy Drainage Pancreatic fluid collections Biopsy Pancreas

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青少年抑郁个体化识别与干预的三级框架

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Science Bulletin 2024年第7期69卷 867-871页

作者：周媛陈旭古若雷项玉涛 Greg Hajcak 王刚 Beijing Key Laboratory of mental Disorders National Clinical Research Center for Mental Disorders&National Center for Mental DisordersBeijing Anding HospitalCapital Medical UniversityBeijing 100088China CAS Key Laboratory of Behavioral Science Institute of PsychologyBeijing 100101China Department of Psychology University of Chinese Academy of SciencesBeijing 100049China Unit of Psychiatry Department of Public Health and Medicinal Administration&Institute of Translational MedicineFaculty of Health SciencesUniversity of MacaoMacao 999078China Centre for Cognitive and Brain Sciences University of MacaoMacao 999078China School of Education and Counseling Psychology Santa Clara UniversitySanta Clara CA 95053USA Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijing 100069China

Depression in adolescents is a significant public health challenge with a high prevalence and negative *** the United States,the lifetime and 12-month prevalence rates of major depressive disorder(MDD)among 13-to 18-year-olds were 11.0%and 7.5%,respectively,prior to *** COVID-19pandemic has further exacerbated the global trend of increasing rates of adolescent depression.

关键词： prevalence adolescent lifetime

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