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Multi-Scale Location Attention Model for Spatio-Temporal Prediction of Disease Incidence

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Intelligent Automation & Soft Computing 2024年第3期39卷 585-597页

作者： Youshen Jiang Tongqing Zhou Zhilin Wang Zhiping Cai Qiang Ni college of Computer National University of Defense TechnologyChangsha410073China technical Service Center for vocational Education National University of Defense TechnologyChangsha410073China School of Computing and Communications Lancaster UniversityLancasterLA14WAUK

Due to the increasingly severe challenges brought by various epidemic diseases,people urgently need intelligent outbreak trend *** disease onset is very important to assist *** of the exist-ing work fails to make full use of the temporal and spatial characteristics of epidemics,and also relies on multi-variate data for *** this paper,we propose a Multi-Scale Location Attention Graph Neural Networks(MSLAGNN)based on a large number of Centers for Disease Control and Prevention(CDC)patient electronic medical records research sequence source data *** order to understand the geography and timeliness of infec-tious diseases,speciﬁc neural networks are used to extract the geography and timeliness of infectious *** the model framework,the features of different periods are extracted by a multi-scale convolution *** the same time,the propagation effects between regions are simulated by graph convolution and attention *** compare the proposed method with the most advanced statistical methods and deep learning ***,we conduct comparative experiments on data sets with different time lengths to observe the predic-tion performance of the model in the face of different degrees of data *** conduct extensive experi-ments on real-world epidemic-related data *** method has strong prediction performance and can be readily used for epidemic prediction.

关键词： Spatio-temporal prediction infectious diseases graph neural networks

Establishment of enzyme-linked immunosorbent assay for beef and lamb contents in cooked meat

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未来食品学报(英文) 2024年第1期4卷 91-96页

作者： Yujing Li Jingjing Liu Sufang Fan Li Zhao Jing Zhang Erjing Zhang Ziran Li Yan Zhang Chunsheng Li Hebei Jiaotong vocational and technical college Shijiazhuang 050035China Biology Institute of Hebei Academy of Sciences Shijiazhuang 050081China Hebei Food Safety Key Labratory Key Laboratory of Special Food Supenvision Technolog for State Market RegpulationHebei Engineering Research Center for Special Food Sagfery and HealthHebei Food Inspection cand Research InstinuteShijiazhuang 050227China college ofLife Sciences Hebei Normal UniversinyShijiazhuang 050024China Julu County Applied Technology Research Instinute Jultu 055250China

In this study,an enzyme 1linked immunosorbent assay(ELISA)was established to detect beef and 1amb components,and its performance was ***-antibody sandwich ELISA was adopted and determined a coating concentration of capture antibody 3G5 of 1:4000,a working concentration of enzyme-labeled antibody 2E7-horseradish peroxidase(HRP)of 1:1000,a sample incubation time of 60 min and a detection antibody reaction time of 60 *** specificity,sensitivity,repeatability and stability of this assay were *** limit of detection for beef and 1amb skeleta1 muscle troponin I was 45 mg/kg,the inter-assay and intra-assay recovery rates ranged from 80.4%to 115.7%,the coefficients of variation were below 13.6%,and the cIoss reaction rates of the tissue components of chicken,duck and fish were below 13.4%.The sandwich ELISA method established in this study is stable and has high *** test results were consistent with the polymerase chain reaction(PCR)method at 50 and 100 g/kg-Therefore,this ELISA method can be used to quantitatively detect beef and 1amb components in meat products.

关键词： Double antibody sandwich enzyme-1inked immunosorbent assay(ELISA) Beef components Lamb components

A VNS-NPGA Approach to Multi-Objective Optimization of Hub-and-spoke Logistics Network

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Journal of Traffic and Transportation Engineering(English Edition) 2024年

作者： Changxi Ma Chuwei Shi Yun Yang Yongpeng Zhao Zhuye Xu Bo Du School of Traffic and Transportation， Lanzhou Jiaotong University Key Laboratory of Railway lndustry on Plateau Railway Transportation Intelligent Management and Control， Lanzhou Jiaotong University School of Tourism and Management， Yangling vocational and technical college School of New Energy and Power Engineering， Lanzhou Jiaotong University National Engineering Research Center of Highway Maintenance Technology， Changsha University of Science & Technology SMART Infrastructure Facility， University of Wollongong

To realize low-cost freight transport in the logistics network and improve the network operation efficiency， a multi-objective optimization model and the corresponding algorithm for a hub-and-spoke logistics network are proposed based on the multi-level location of hub points and channels layout. By considering the structure of the multi-level hub-and-spoke logistics network and the features of the connectivity between the hub and spoke points， the multi-objective optimization model is constructed with two objectives of minimizing the total network operation costs and the total network service time. By considering the characteristics of decision variables and models， a Variable Neighborhood Search (VNS)-Niched Pareto Genetic Algorithm (NPGA) approach with a three-stage encoding structure chromosome is proposed， where the VNS algorithm nested in NPGA is used for individual variable neighborhood search to optimize individual channel level genes， and NPGA is adopted to solve the multi-objective optimization model. To evaluate the performance of the proposed VNS-NPGA approach， a real-life case study based on a small-scale Australia Post data set was conducted， and 25 nodes of the Australia Post and 14 nodes of the Gansu Province 3-level hub-and-spoke logistics networks were established， respectively. The analysis results indicated that the network structure of multi-level hub points could avoid the detour problem existing in the traditional hub-and-spoke network， and showed better applicability in the narrow geographical structure. Compared to the traditional multi-objective evolutionary algorithms， VNS-NPGA can obtain better solutions through the distributed optimization of channel levels， avoiding the problem that a single algorithm cannot effectively deal with coupling relationships in genes.

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Effectiveness of fecal DNA syndecan-2 methylation testing for detection of colorectal cancer in a high-risk Chinese population

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1361-1373页

作者： Wen-Feng Luo Yu-Ting Jiao Xiao-Ling Lin Ying Zhao Sheng-Bo Wang Jian Shen Jie Deng Yu-Feng Ye Ze-Ping Han Fang-Mei Xie Jin-Hua He Yu Wan Central Laboratory of Panyu Central Hospital Guangzhou Panyu Central HospitalGuangzhou 511400Guangdong ProvinceChina South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Guangzhou Panyu Central HospitalGuangzhou 511400Guangdong ProvinceChina Digestive Disease Center Guangzhou Panyu Central HospitalGuangzhou 511400Guangdong ProvinceChina Shunde vocational and technical college Foshan 528300Guangdong ProvinceChina Medical Imaging Institute of Panyu Guangzhou Panyu Central HospitalGuangzhou 511400Guangdong ProvinceChina

BACKGROUND Colorectal cancer(CRC)is among the most prevalent and life-threatening malignancies ***-2 methylation(mSDC2)testing has emerged as a widely used biomarker for early detection of CRC in stool and serum ***(CRC)is among the most prevalent and life-threatening malignancies ***2 testing has emerged as a widely used biomarker for early detection of CRC in stool and serum *** To validate the effectiveness of fecal DNA mSDC2 testing in the detection of CRC among a high-risk Chinese population to provide evidence-based data for the development of diagnostic and/or screening guidelines for CRC in *** A high-risk Chinese cohort consisting of 1130 individuals aged 40-79 years was selected for evaluation via fecal mSDC2 *** and specificity for CRC,advanced adenoma(AA)and advanced colorectal neoplasia(ACN)were ***-risk factors for the incidence of colorectal lesions were determined and a logistic regression model was constructed to reflect the efficacy of the *** A total of 1035 high-risk individuals were included in this study according to established *** them,16 suffered from CRC(1.55%),65 from AA(6.28%)and 189 from non-AAs(18.26%);150 patients were diagnosed with polyps(14.49%).Diagnoses were established based upon colonoscopic and pathological *** of the mSDC2 test for CRC and AA were 87.50%and 40.00%,respectively;specificities were 95.61%for other *** predictive values of the mSDC2 test for CRC,AA and ACN were 16.09%,29.89%and 45.98%,respectively;the negative predictive value for CRC was 99.79%.After adjusting for other high-risk covariates,mSDC2 test positivity was found to be a significant risk factor for the occurrence of ACN(P<0.001).CONCLUSION Our findings confirmed that offering fecal mSDC2 testing and colonoscopy in combination for CRC screening is effective for earlier detection of malignant colorectal lesions in a high

关键词： Colorectal cancer Syndecan-2 DNA methylation Chinese population

A Study on the Challenges of Human-Centric Cyber-Security and the Guarantee of Information Quality

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Journal of Information Security 2024年第2期15卷 218-231页

作者： Mohammed Hussein Kurdi Mohsen Denden David Paul Department of Cyber-Security National Events Center Riyadh Saudi Arabia Department of Computer and Information Technologies Technical College of Telecommunication and Information Riyadh TCTI Technical and Vocational Training Corporation TVTC Riyadh Saudi Arabia Department of Computer Science Higher Institute of Applied Sciences of Sousse University of Sousse Sousse Tunisia School of Science & Technology University of New England Armidale Australia

Information security and quality management are often considered two different fields. However, organizations must be mindful of how software security may affect quality control. This paper examines and promotes methods through which secure software development processes can be integrated into the Systems Software Development Life-cycle (SDLC) to improve system quality. Cyber-security and quality assurance are both involved in reducing risk. Software security teams work to reduce security risks, whereas quality assurance teams work to decrease risks to quality. There is a need for clear standards, frameworks, processes, and procedures to be followed by organizations to ensure high-level quality while reducing security risks. This research uses a survey of industry professionals to help identify best practices for developing software with fewer defects from the early stages of the SDLC to improve both the quality and security of software. Results show that there is a need for better security awareness among all members of software development teams.

关键词： Cyber Security Development Methodology Information Quality Human-Centric SDLC Quality Assurance

Evaluation and Empirical Research on Teachers’ Information Literacy in the Context of Smart Education

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Journal of Contemporary Educational Research 2024年第3期8卷 211-220页

作者： Chenyue Hu Chongqing Youth vocational and technical college Chongqing 401320China

The development of smart education has led to the integration of emerging technologies such as artificial intelligence with *** is a prerequisite for teachers to have high information literacy for conducting education and teaching *** study conducted a questionnaire survey on 412 teachers in a certain *** results showed that teachers’information literacy is above the middle level,and there are significant differences in information literacy between teaching experience and educational *** evaluation showed that information ethics,information awareness,and information application have a significant positive impact on professional development,and information knowledge and information awareness have a positive predictive effect on information ethics.

关键词： Teachers’information literacy Smart education Empirical research

Effects of High-Intensity Intermittent Training on Metabolic Parameters and Irisin Levels in High-Fat-Fed Rats

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Journal of Clinical and Nursing Research 2024年第8期8卷 52-59页

作者： Dongping Tan Wenbin Zhang Longxia Zheng Huijun Lin Guangdong vocational Institute of Sport Guangdong 510663China

Objective:To investigate the effects of high-intensity intermittent training(HIIT)on preventing significant weight gain and provide scientific theoretical support and practical guidance for reducing the occurrence of ***:Twenty-four Sprague-Dawley rats were randomly divided into four groups:the control sedentary group(CS),the high-fat sedentary group(HS),the high-fat continuous exercise group(HE),and the high-fat intermittent exercise group(HI).The HE and HI groups underwent five days of continuous low-intensity exercise and eight weeks of high-intensity intermittent *** monitoring included measurements of food intake and body *** automatic biochemical analyzer was used to assess blood lipid and glucose levels,while ELISA kits measured serum insulin and irisin content.H&E staining was used to observe adipocyte ***:In the HS group,body weight,blood lipid levels,blood glucose levels,and adipocyte size significantly increased,while the QUICKI index *** the HI group,body weight,blood lipid levels,blood glucose levels,and adipocyte size decreased,and the QUICKI index *** effects of high-intensity intermittent exercise were superior to those of continuous low-intensity *** the HI group,serum irisin levels did not change significantly after exercise,while in the HE group,there was a slight upward trend in irisin ***:A high-fat diet induced abnormal metabolism in *** effectively prevents metabolic abnormalities induced by a high-fat diet,and its effects are more pronounced than those of low-intensity *** stimulates the secretion of blood irisin,affecting secretion levels,and may represent a novel mechanism for maintaining metabolic *** has important implications for controlling significant weight gain.

关键词： High intensity interval training Rats Metabolic characterization Irisin

Formulation of Work-Study Combined and Result-Oriented Integrated Curriculum Standards

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Medicinal Plant 2024年第3期15卷 79-83页

作者： Lianfang LI Chunhua DU Fen YANG Yun LI Yanfei NIU Yunnan Technician college(Yunnan Industry Trade vocational college) Kunming 650300China Yunnan Baiyao Group Traditional Chinese Medicine Resources Co. Ltd.Kunming 650300China

According to the Annex technical Regulations for Integrated Curriculum Development(Trial)in Document No.30 of the General Office of the Ministry of Human Resources and Social Security(2012),this paper studies the formulation of the curriculum standards for the integration of Chinese medicinal materials *** focus on the formulation ideas of the curriculum standards for the integration of Chinese medicinal materials production,the formulation process of the curriculum standards for the integration of Chinese medicinal materials production,including the description of typical work tasks,the determination of curriculum objectives,the analysis of study content,the description of referential study tasks,teaching implementation suggestions,assessment and evaluation suggestions,which can provide a reference for the development and research of other related integrated courses.

关键词： Integration of work and study Work process Curriculum standards Production of Chinese medicinal materials Typical work tasks Referential study tasks

Microstructure of Fe-Based Alloy Composite Coatings Reinforced by Ti(C_(0.3)N_(0.7)) Particles Through Laser Cladding Technology

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Journal of Iron and Steel Research International 2013年第8期20卷 78-82页

作者： QI Yong-tian CAO Zhao-xia SHENG Li-ying CAO Run-ping Inner Mongolia Baotou vocational and technical college

Fe-based alloy layer reinforced by Ti（C,N） particles was produced on the surface of cast steel. X ray dif fraction （XRD） was used for phase identification in the composite coating. The microstructure of laser cladding layer was analyzed by means of optical microscope （OM）, electron probe microscope analyzer （EPMA）, scanning electron microscope （SEM） and transmission electron microscope （TEM）. The results show that Ti（C0.3 N0.7 ） particle is in-troduced by an in situ metallurgical reaction of TiN particle and graphite powder in the process of laser cladding. The shape of lots of Ti（C0.3 N0.7） particle is irregular. The sizes of Ti（C0. 3N0. 7） particles range from 0. 1 to 6.0 μm, and they are dispersed evenly in the matrix, which is fine dendritic or cellular crystal. A new kind of phase named Ti（C0.3 N0. 7 ） parti-cles are tightly bonded with α-Fe microstructure, and there is a clean and smooth phase interface between ceramic re-inforcement phase and the matrix.

关键词： Ti(C0.3 N0.7 ) particle TiN laser cladding microstructure