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Eosinophilic Granulomatosis with Polyangiitis and Bowel Perforation: Case Report

Journal of Pharmacy and Pharmacology 2022年第11期10卷 283-287页

作者： PauloÁtila da Silva Viana Leonardo de Oliveira Cavalcante Liz Miranda Mateus Lara Farias Lustosa da Costa Deborah Giovanna Santana Rabelo medical residency in rheumatology General Hospital Dr.Cesar CalsCeará60.015-050Brazil Service Coordinator medical residency in rheumatology General Hospital Dr.Cesar CalsCeará60.015-050Brazil medical-Academic League of rheumatology of Fortaleza Christu University CenterFortaleza 60.160-230Brazil medical-Academic League of rheumatology of Fortaleza Cearástate UniversityFortaleza 60.714-903Brazil

The small and medium sized vessels vasculitis included in the group of vasculitis associated with anti-neutrophil cytoplasmic antibodies,is a rare disease characterized by the presence of vasculitis in association with asthma and *** objective of this report is to describe a case with a typical initial presentation of eosinophilic granulomatosis with polyangiitis-EGPA,that evolved with atypical clinical manifestations and findings in complementary *** the clinical evolution and comprehending the therapeutic response of the patient in question,with scientific embasement on published medical literature.

关键词： Granulomatosis with polyangiitis Vasculitis Asthma Eosinophilia Acute abdomen

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Protocol for a randomized controlled trial of electroacupuncture in the management of patients with axial spondyloarthritis in Singapore(E-AcuSpA)

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rheumatology & Autoimmunity 2021年第2期1卷 104-114页

作者： Warren Fong Yu Heng Kwan Su-An Quek Ader Lim Chiah Yuen Wong Shin Yoong Chua Hui Chin Tan Clara Eng Choy Tip Tan Bao Qiang Dong Youyi Huang Chuen Seng Tan Bee Choo Tai Ting Hui Woon Jie Kie Phang Hwee Ling Koh Ying Ying Leung Julian Thumboo TrulsØstbye Department of rheumatology and Immunology Singapore General HospitalSingaporeSingapore Duke-NUS medical School SingaporeSingapore Department of Medicine Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Internal Medicine residency SingHealthSingaporeSingapore Programme in Health Services and Systems Research Duke-NUS Medical SchoolSingaporeSingapore Department of Pharmacy National University of SingaporeSingaporeSingapore Singapore Thong Chai medical Institution SingaporeSingapore Acupuncture and Tuina College Liaoning University of Traditional Chinese MedicineShenyangLiaoningP.R.China Saw Swee Hock School of Public Health National University of SingaporeSingaporeSingapore

Background:Despite therapeutic advances,treatment of patients with axial spondyloarthritis(axSpA)continue to pose as a challenge as many do not respond well to conventional Western medications,such as nonsteroidal anti-inflammatory drugs(NSAIDs)and biologic diseasemodifying antirheumatic drugs(bDMARDs).Hence,acupuncture is a possible *** studies found electroacupuncture to be better than manual acupuncture,though no trials have been conducted in patients with *** clinical trial aims to evaluate the clinical efficacy,safety,and cost-effectiveness of electroacupuncture compared to manual acupuncture for patients with ***/Design:This randomized controlled trial will recruit 100 patients diagnosed with axSpA,who have active disease despite NSAIDs and *** patients will be randomized to receive either electroacupuncture or manual acupuncture in a 1:1 *** participants will receive standard rheumatologic care in addition to 20 acupuncture *** mean difference in Bath Ankylosing Spondylitis Disease Activity Index score between the 2 groups over 12 weeks will serve as the primary *** outcomes include improvements in other clinical,quality of life,and economic outcomes over 24 *** adverse events will be ***:Results from this trial may provide evidence regarding the clinical effectiveness,safety,and cost-effectiveness of electroacupuncture compared to manual acupuncture for patients with axSpA,and guide implementation into clinical *** of this trial include the lack of patient blinding,use of a repeated measures design,and possible variation in acupuncture technique amongst the various Traditional Chinese Medicine practitioners.

关键词： axial spondyloarthritis complementary and alternative medicine electroacupuncture randomized controlled trial Traditional Chinese Medicine

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