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China medical Abstracts(Internal medicine) 2024年第2期41卷 68-69页

作者：方明 2nd Clin med Coll Anhui CM UnivHefei 230061

Objective To observe the effects of moxibustion on colonic mast cell degranulation and inflammatory factor expression in rats with diarrhea-predominant irritable bowel syndrome(IBS-D),and explore the potential mechanism of moxibustion in treating *** In forty-five rat pups born from 5 healthy SPF-grade pregnant SD rats,8 rats were randomly selected as normal group,and the remaining 37 rats were intervened with maternal separation,acetic acid enema,and chronic restraint stress to establish the IBS-D *** successfully modeled 32 rats were then randomly assigned to a model group,a ketotifen group,a moxibustion group,and a moxibustion-medication group,with 8 rats in each *** rats in the ketotifen group were intervened with intragastric administration of ketotifen solution(10 mL/kg).

关键词： moxibustion colonic inflammatory

Analysis of the clinical characteristics of V4 segment steal blood in the vertebral artery

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China medical Abstracts(Internal medicine) 2024年第2期41卷 125-126页

作者：刘洋 Dept Neurol 2nd Affil HospQiqihar Med CollQiqihar 161006

Objective To explore the clinical characteristics of unilateral vertebral artery V4 segment occlusive lesions(severe stenosis or occlusion),where the contralateral vertebral artery can be compensated through blood flow and reverse supplytothe posterior inferior cerebellarartery(PICA).Methods This study is a retrospective case series of 66 patients with V4 segment occlusive lesions of unilateral vertebral artery diagnosed and treated from June 2020 to October *** data were retrospectively collected,and their hemodynamic characteristics and imaging data were *** Of the 66 cases,11 patients(16.7%)with V4 segment occlusive disease showed the blood flow of the vertebral artery on the opposite side of the lesion on the digital subtraction angiography(DSA),which can be reversely stolen to the posterior inferior cerebellar artery of the diseased side through the confluence point of the vertebrobasilar artery through the distal end of the ipsilateral vertebral artery *** to the lack of literature on this pathway and based on the characteristics of previous definitions of subclavian artery steal and carotid artery steal,we referred to this pathway as the vertebral artery V4 segment *** 6 patients(9.1%)。

关键词： vertebral artery clinical

Effect and mechanism of ubiquitin-like protein FAT10 on AngⅡinduced endothelial cell inflammation

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China medical Abstracts(Internal medicine) 2024年第1期41卷 39-40页

作者：卓雯 Dept Cardiovasc med 2nd Affil HospNanchang UnivNanchang 330006

Objective To investigate the role and related mechanism of ubiquitin-like protein FAT10 in the angiotensinⅡ(AngⅡ)-induced endothelial cell inflammatory *** The Western blot was used to detect the protein expression of FAT10 in 16-week old WKY rat carotid artery,thoracic aorta artery,renal artery and vascular smooth muscle cells (VSMC).

关键词： AngⅡ ubiquitin artery

Association between different obesity indicators and carotid intima-media thickness in patients with type 2 diabetes mellitus

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China medical Abstracts(Internal medicine) 2024年第1期41卷 27-28页

作者：崔茜 Dept Endocrinol Affil Changzhou No.2 People's HospNanjing Med UnivChangzhou 213000

Objective To explore the relationship between different obesity indicators and carotid intima-media thickness (CIMT) in patients with type 2 diabetes mellitus (T2DM).Methods A total of 1 762 T2DM patients who visited the Endocrinology Department of Changzhou Second People’s Hospital Affiliated to Nanjing medical University and the Integrated Traditional Chinese and Western medicine Hospital Affiliated to Nanjing University of Traditional Chinese medicine from January2019 to February 2022 were enrolled in this study.

关键词： obesity T2DM patients

Heat-sensitive moxibustion combined with Xiangwu powder for erectile dysfunction with kidney deficiency and blood stasis:a randomized controlled trial

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China medical Abstracts(Internal medicine) 2024年第2期41卷 73-74页

作者：高五芝 Dept Reprod med Henan Prov TCM Hosp2nd Affil HospHenan CM UnivZhengzhou 450002

Objective To observe the clinical efficacy of heatsensitive moxibustion combined with Xiangwu powder in treating erectile dysfunction with kidney deficiency and blood *** A total of 80 patients with erectile dysfunction of kidney deficiency and blood stasis were randomly divided into a comprehensive group(40 cases,1 case dropped out)and a Chinese herb group(40 cases,2 cases dropped out).In the Chinese herb group,Xiangwu powder was applied orally,one dose per *** the basis of the Chinese herb group,heat-sensitive moxibustion was applied after detecting the heat-sensitive points in the areas of Guanyuan(CV 4),Zhongji(CV 3),Qihai(CV 6)and bilateral Xuehai(SP 10),Sanyinjiao(SP 6)in the comprehensive group,once a day,5 times a *** groups were treated for 4 *** international index of erectile function-5(IIEF-5)score,erectile hardness score(EHS).

关键词： moxibustion erectile kidney

Impact of calcification on the diagnostic accuracy of quantitative flow fraction based on coronary CT angiography

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China medical Abstracts(Internal medicine) 2024年第1期41卷 1-2页

作者：马文珊 Sch med Imaging Binzhou Med UnivYantai 264003

Objective To investigate the effect of calcification on the diagnostic accuracy of the quantitative flow fraction (CT-QFR) derived from coronary CT angiography(CCTA).Methods A total of 244 patients (471 coronary arteries) who underwent both CCTA and invasive coronary angiography(ICA) for suspected coronary artery disease between 2019 and 2021 were included in the *** analyses were conducted at the vessel level using CCTA and ICA images.

关键词： coronary angiography arteries

Minimalistic approach to left atrial appendage occlusion guided by cardiac computed tomography angiography

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Journal of Geriatric Cardiology 2024年第4期21卷 431-442页

作者： Xian-Sai MENG Qing-Song WANG Xin-Yan WANG Xu LU Yang MU Jing WANG Ting-Ting SONG Yun-Dai CHEN Tao CHEN Jun GUO Graduate School of Chinese PLA medical College BeijingChina Senior Department of Cardiology the Sixth Med-ical CenterChinese PLA General HospitalBeijingChina

OBJECTIVE To assess the feasibility and safety of the minimalistic approach to left atrial appendage occlusion(LAAO) guided by cardiac computed tomography angiography(CCTA).METHODS Ninety consecutive patients who underwent LAAO, with or without CCTA-guided, were matched(1:2). Each step of the LAAO procedure in the computed tomography(CT) guidance group(CT group) was directed by preprocedural CT planning. In the control group, LAAO was performed using the standard method. All patients were followed up for 12 months, and device surveillance was conducted using *** A total of 90 patients were included in the analysis, with 30 patients in the CT group and 60 matched patients in the control group. All patients were successfully implanted with Watchman devices. The mean ages for the CT group and the control group were 70.0 ± 9.4 years and 68.4 ± 11.9 years(P = 0.52), respectively. The procedure duration(45.6 ± 10.7 min vs. 58.8 ± 13.0 min,P 2.4 day vs. 9.6 ± 2.8 day, P = 0.001) in the CT group was significantly shorter compared to the control group. However, the total radiation dose was higher in the CT group compared to the control group(904.9 ± 348.0 m Gy vs.711.9 ± 211.2 m Gy, P = 0.002). There were no significant differences in periprocedural pericardial effusion(3.3% vs. 6.3%, P = 0.8) between the two groups. The rate of postprocedural adverse events(13.3% vs. 18.3%, P = 0.55) were comparable between both groups at 12 months *** CCTA is capable of detailed LAAO procedure planning. Minimalistic LAAO with preprocedural CCTA planning was feasible and safe, with shortened procedure time and acceptable increased radiation and contras consumption. For patients with contraindications to general anesthesia and/or transesophageal echocardiography, this promising method may be an alternative to conventional LAAO.

关键词： anesthesia matched approach

Hemodynamic changes with serial balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

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China medical Abstracts(Internal medicine) 2024年第2期41卷 99-100页

作者：汪薇 Dept Respir&Critical Care med Beijing Chaoyang HospCapital Med UnivBeijing Instit Respir MedBeijing 100020

Objective To monitor hemodynamic changes during serial balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH).Methods General clinical data of CTEPH patients diagnosed from October 2017 to January 2022 in Beijing Chaoyang Hospital were collected,and 83 patients who underwent at least 1 BPA treatment were included to analyze their 6 min walking distance,WHO functional class,N-terminal B-type natriuretic peptide precursor(NT-proBNP),troponin I (cTnI) and haemodynamic indices.

关键词： balloon hypertension angioplasty

Establishment of abdominal aortocaval fistula in adenine-induced renal failure rats

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China medical Abstracts(Internal medicine) 2024年第2期41卷 115-116页

作者：张艺斐 Shandong med Sci Acad Shandong 1st Med UnivJinan 250000

Objective To explore the construction of abdominal aortocaval fistula(ACF)model in adenine-induced renal failure rats,and to provide a suitable animal model for subsequent mechanism and intervention *** Adult female Sprague-Dawley rats(250-300 g)were fed with 0.75%adenine diet(renal failure group,n=60)and the same diet without adenine(control group,n=10)for 4 weeks,and the rats were randomly grouped by block randomization method with a ratio of 6:*** rats in the renal failure group were randomly selected by block randomization method at a ratio of 1:1 to undergo laparotomies to establish ACF models(renal failure+ACF group).The serum creatinine,blood urea nitrogen detection and Masson staining were used to evaluate the establishment of renal failure *** animal ultrasound imaging system was applied to verify the successful construction of the ACF *** 6 weeks of ACF observation,blood samples were collected from the heart of rats,and ACF-vascular tissues were collected for pathological study(HE staining).Results At 4 weeks of feeding.

关键词： rats fistula renal

Comparative study of ^(18)F-PSMA-1007,^(18)F-FDG PET/CT and mpMRI in the diagnosis of prostate cancer

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China medical Abstracts(Internal medicine) 2024年第2期41卷 66-67页

作者：姜一逸 Dept Nucl med Affil Taizhou People's HospNanjing Med UnivTaizhou 225300

Objective To compare the diagnostic efficacy of ^(18)Fprostate specific membrane antigen(PSMA)-1007 PET/CT,18F-FDG PET/CT and multi-parameter MRI(mpMRI)in prostate cancer(PCa).Methods Retrospective analysis was conducted on data from 22 patients((72.6±6.2)years)with pathologically confirmed PCa in the Affiliated Taizhou People's Hospital of Nanjing medical University between April 2021 and September *** patients underwent 18F-PSMA-1007 PET/CT,18F-FDG PET/CT,and mpMRI examination within 30 d,and the imaging parameters were collected,including PSMASUVnax FDG-SUV_(max),minimum apparent diffusion coefficient(ADC_(min)),mean apparent diffusion coefficient(ADC_(mean)),PSMA-SUV_(max)/ADCm,in PSMA-SUV ma ADC_(mean),FDG-SUV_(max)/ADC_(min),FDG-SUVmV_(max)/ADC,nean Patientswere divided into groupsbasedonthe International Society of Urological Pathology(ISUP)grading(≤3 vs>3)and serum total prostate specific antigen(TPSA;≤20μg/L us>20μg/L).

关键词： PET/CT PSMA diagnosis