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GAN-GMHI: a generative adversarial network with high discriminative power for microbiome-based disease prediction

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Journal of Genetics and Genomics 2023年第12期50卷 1026-1028页

作者： Yuxue Li Gang Xie Yuguo Zha Kang Ning moe key laboratory of Molecular Biophysics Hubei Key Laboratory of Bioinformatics and Molecular-imagingCenter of Artificial Intelligence BiologyDepartment of Bioinformatics and Systems BiologyCollege of Life Science and TechnologyHuazhong University of Science and TechnologyWuhanHubei 430074China

With the rapid development of research on the human gut microbiome,associations between the microbiome and various complex chronic diseases have been revealed(Bergot et al.,2019).These advancements provide great oppor... 详细信息

关键词： prediction diseases

Clock recovery from NRZ data at 10 Gb/s using SOA loop mirror and mode-locked fiber ring laser based on SOA

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Chinese Optics Letters 2006年第2期4卷 72-75页

作者：尹丽娜刘国明伍剑林金桐 key laboratory of Optical Communication and Lightwave Technologies of moe

All optical clock recovery from non return-to-zero （NRZ） data using an semiconductor optical amplifier （SOA） loop mirror and a mode-locked SOA fibcr lascr is firstly schematically explained and experimentally demonstrated at 10 Gb/s. Furthermore, the pulse quality of tile recovered cluck is cffcctivcly improved by using a continuous-wave （CW） assist light in the gain region of SOA, through which the amplitude modulation is reduced from 57.2% to 8.47%. This scheme is a promising method for clock recovery from NRZ data in the future all-optical communication networks.

关键词： NRZ Clock recovery from NRZ data at 10 Gb/s using SOA loop mirror and mode-locked fiber ring laser based on SOA mode ring data

Denitrification and the controlling factors in Yunnan Plateau Lakes(China): Exploring the role of enhanced internal nitrogen cycling by algal blooms

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Journal of Environmental Sciences 2019年第2期31卷 349-358页

作者： Sifeng Wu Zhen Wu Zhongyao Liang Yong Liu Yilin Wang College of Environmental Sciences and Engineering Key Laboratory of Water and Sediment Sciences (MOE)Peking University College of Environmental Sciences and Engineering Key Laboratory of Water and Sediment Sciences(MOE)Peking University

Denitrification plays an important role in nitrogen(N) removal in freshwater *** internal process regulates the fluctuations of N concentration, especially for lakes with high nutrients concentrations and long residence time. Lakes in Yunnan plateau(southwestern China) provide typical cases, while studies in this region have been ***, we studied denitrification of two lakes(Lake Dianchi in hypereutrophic state and Lake Erhai in mesotrophic) in this region. We used acetylene inhibition technique to quantify potential denitrification rate(PDR) of these lakes in April and August, 2015 and 2016. PDR of the sediments ranged 0–1.21 μmol/(N·m^2·hr), and that of overlying water ranged 0–0.24 μmol/(N·L·hr). Then, we used Least Angle Regression to determine the controlling factors for denitrification. Nutrients controlled PDR from two aspects: providing essential nitrogen sources; and affecting the richness and metabolism of denitrifying bacteria. In April, both aspects limited PDR; while only nitrogen sources limited PDR in August, due to depleted nitrate and enhanced denitrifying bacteria activity. Ammonia was most significant to denitrification, indicating that nitrate from nitrification transported to the bottom of wellmixed lake provide major N source by denitrification. The high PDR and low nitrate concentrate in August were evidence of an enhanced internal N cycling by algal blooms.

关键词： Denitrification Controlling factors Lake Dianchi Lake Erhai Algal bloom Internal cycling

Improved turn-on behavior in a diode-triggered silicon-controlled rectifier for high-speed electrostatic discharge protection

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Science China(Information Sciences) 2019年第6期62卷 79-86页

作者： Lizhong ZHANG Yuan WANG Yize WANG Xing ZHANG YANDong HE key laboratory of Microelectronic Devices and Circuits (moe) Institute of MicroelectronicsPeking University

A conventional diode-triggered silicon-controlled rectifier(DTSCR) structure with a layout strategy for electrostatic discharge(ESD) protection is presented and confirmed in a 65-nm CMOS *** modified device is featured by a scaled-down trigger-diode string, which shortens its turn-on time using a variable scaling factor. To confirm the parasitic resistance adjustments of the modified DTSCR, transmission line pulsing(TLP)/very fast transmission line pulsing(VF-TLP) tests and simulations are performed on the device. Compared to a conventional DTSCR, this structure exhibits an improved turn-on speed and robustness, which are suitable for I/O protection of ESD events in the nanosecond range, particularly the charged-device model(CDM) event.

关键词： diode triggered silicon controlled rectifier(DTSCR) electrostatic discharge(ESD) transmission line pulsing(TLP) very fast transmission line pulsing(VF-TLP) turn-on behavior

Preparation of Polypropylene/Poly(styrene-co-(butyl methacrylate)) Nanoblends by Diffusion and Subsequent Copolymerization of Monomers in Isotactic Polypropylene Pellets

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Chinese Journal of Polymer Science 2015年第10期33卷 1380-1388页

作者： Hai-yue Qiu Fang Chen 郭朝霞于建 key laboratory of Advanced Materials(moe) Department of Chemical Engineering Tsinghua University

The diffusion and subsequent copolymerization of styrene （St）/butyl methacrylate （BMA） mixed monomers in iPP pellets to prepare copolymer nanoblends were investigated. The diffusion step was carded out at 90 ℃ for 2 h in water, and the copolymerization was initiated by the addition of BPO with the aid of a small amount of St. The diametrical distributions of both St and BMA units and their ratio St/BMA were investigated by micro FTIR. Both St and BMA can diffuse into the centres of iPP pellets. The diametrical distribution of St/BMA ratio is constant in all the copolymer blends. The copolymer composition depends on the comonomer feed ratio. The molecular weights of the copolymers were measured by GPC after extraction with tetrahydrofuran. The phase morphology of the copolymer blends was investigated by FESEM, showing the average particle sizes of less than 100 nm. DSC measurements show that the diffusion and subsequent copolymerization of St/BMA monomers only occur in the amorphous regions of iPP pellets.

关键词： Polypropylene Polymer blend Diffusion Copolymerization

Optical and Mechanical Properties of Polyurethane/Surface-modified Nanocrystalline Cellulose Composites

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Chinese Journal of Polymer Science 2014年第10期32卷 1363-1372页

作者： Hao Zhang Ying She Xue Zheng He-yu Chen 蒲俊文 moe key laboratory of Wooden Material Science and Application Beijing Forestry University

in order to improve the optical and mechanical performances of waterborne polyurethane （WPU）, nanocrystalline cellulose （NCC）/WPU composites were synthesized in this study. NCC （prepared by acid hydrolysis of cotton fiber） was modified by （3-aminopropyl）triethoxysilane （APTES） to enhance its compatibility with WPU, and the surface-modified NCC was characterized by grafting ratio, crystallinity and contact angle （CA）. NCC/WPU composites were examined by scanning electron microscopy （SEM）, X-ray powder diffraction （XRD） and thermogravimetric analysis （TG）. The anti-yellowing property, specular gloss, pencil hardness, and abrasion resistance of NCC/WPU composites were investigated by the methods of Chinese National Standards GB/T 23999-2009, GB/T 9754-2007, GB/T 6739-2006 and GB/T 1768-2006, respectively. The results showed that the grafting ratio of NCC modified by 6% APTES was 36.01% and the crystallinity of modified NCC was decreased with the enhancement of APTES. CA of the modified NCC was decreased by 28.8% and the nanoparticles were homogeneously dispersed in the WPU matrix. The XRD patterns of the NCC/WPU composites were relatively steady, while the thermal stability of the composites was enhanced by 6.7% with 1.0 wt% modified NCC. Modified NCC affected the specular gloss of NCC/WPU composites more obviously than the anti-yellowing property. The pencil hardness of NCC/WPU composites was increased from 2H to 4H by addition of NCC and the abrasion resistance of the composites was enhanced significantly. In general, NCC/WPU composites showed significant improvements in the optical and mechanical performances.

关键词： Nanocrystalline cellulose Waterborne polyurethane Cotton Optical and mechanical properties Nanocomposites.

A review of down-hole tubular string buckling in well engineering

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Petroleum Science 2015年第3期12卷 443-457页

作者： De-Li Gao Wen-Jun Huang moe key laboratory of Petroleum Engineering China University of Petroleum

Down-hole tubular string buckling is the most classic and complex part of tubular string mechanics in well engineering. Studies of down-hole tubular string buckling not only have theoretical significance in revealing the buckling mechanism but also have prominent practical value in design and control of tubular strings. In this review, the basic principles and applicable scope of three classic research methods （the beam-column model, buck- ling differential equation, and energy method） are intro- duced. The critical buckling loads and the post-buckling behavior under different buckling modes in vertical, inclined, horizontal, and curved wellbores from different researchers are presented and compared. The current understanding of the effects of torque, boundary condi- tions, friction force, and connectors on down-hole tubular string buckling is illustrated. Meanwhile, some unsolved problems and controversial conclusions are discussed. Future research should be focused on sophisticated description of buckling behavior and the coupling effect of multiple factors. In addition, active control of down-hole tubular string buckling behavior needs some attention urgently.

关键词： Down-hole tubular mechanics Tubular stringbuckling Wellbore configuration Boundary condition Friction force

A Method to Accelerate the Gelation of Disulfide-crosslinked Hydrogels

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Chinese Journal of Polymer Science 2015年第1期33卷 118-127页

作者： Xiaoshan Yan Xiaotong Yang 童新明黄延宾 key laboratory of Advanced Materials (moe) Department of Chemical EngineeringTsinghua University

A glutathione-disulfide-ended poly（ethylene glycol）（GSSG-PEG-GSSG） was designed. It is a much more efficient accelerator than glutathione disulfide（GSSG） for the gelation of an 8arm-PEG-SH polymer solution, and the gelation time can be tuned from hours to minutes at the physiological p H and temperature. A mechanism was proposed to explain the different behaviors of the GSSG and GSSG-PEG-GSSG gelation systems. Due to the ever-going thiol-disulfide exchange reaction, the thiol-disulfide hydrogels also showed interesting swelling behavior.

关键词： Thiol-disulfide exchange In situ gelation Glutathione PEG.

Research on the Performance of Supercritical CO_2 Dry Gas Seal with Different Deep Spiral Groove

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Journal of Thermal Science 2019年第3期28卷 547-558页

作者： DU Qiuwan ZHANG Di moe key laboratory of Thermo-Fluid Science and Engineering Xi'an Jiaotong University

The performance of supercritical CO_2(SCO_2) dry gas seal(DGS) with different deep spiral groove is investigated with the thermal-fluid-solid coupling method. The performance parameters of DGSs with five different kinds of grooves are obtained. The influence of inlet temperature, inlet pressure, velocity and film thickness on performance is analyzed compared with air DGS. The average film pressure, open force and leakage decrease while the average face temperature and flow velocity increase as the spiral groove number increases. The average film pressure, average face temperature, open force and leakage of DGS with radial different deep groove are higher than those of DGS with circumferential different deep groove respectively under the same spiral groove number while the average flow velocity is the opposite. SCO_2 DGS can generate larger average film pressure, open force and leakage with lower average face temperature than air DGS. SCO_2 DGS could maintain better sealing performance despite larger leakage with the variations of inlet temperature, inlet pressure, velocity and film thickness. The variables hold a more remarkable influence on SCO_2 DGS compared with air DGS.

关键词： supercritical carbon dioxide different deep spiral groove dry gas seal thermal-fluid-solid coupling method