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The mediating role of sleep qualityon the relationship between internet gaming disorder and perceived stress and suicidal behaviour among Indian medical students

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General Psychiatry 2023年第3期36卷 175-188页

作者： Sunny Garg Aakanksha Kharb Deepika Verma Ritu Antil Binika Khanna Ritika Sihag Divya Lamba Psychiatry Bhagat Phool Singh Government Medical College for WomenKhanpur KalanSonipatHaryanaIndia mbbs Internship Bhagat Phool Singh Government Medical College for WomenKhanpur KalanSonipatHaryanaIndia mbbs Student Final Prof Bhagat Phool Singh Government Medical CollegeforWomenKhanpur KalanSonipatHaryanaIndia

Background In the recent digital era,individuals with internet gaming disorder(IGD)have reported a much higher prevalence of poor sleep quality,perceived stress and suicidal behaviour.However,the underlying mechanisms for these psychological problems remain unknown.Aims The primary aims of this study were to explore the mediating role of sleep quality on the relationship between IGD and the health outcomes of perceived stress and suicidal behaviour and to assess the prevalence and risk factors for IGD among medical students.Methods A cross-sectional study enrolling 795 medical students from two medical colleges in a rural area of North India was conducted from April to May 2022.The study participants were chosen using a stratified random sampling approach.A self-administered questionnaire was used to collect data,including sociodemographic and personal information and gaming characteristics.The study also included the Gaming Disorder and Hazardous Gaming Scale,the Pittsburgh Sleep Quality Index,the Perceived Stress Scale-10 and the Suicide Behaviors Questionnaire-Revised to measure IGD,sleep quality,perceived stress and suicidal behaviour,respectively.Multiple logistic regression for the risk factors and Pearson's correlation test for the relationship between variables were used.Hayes'PROCESS macro for SPSS was employed to carry out mediation analysis.Results Among the 348 gamers with a mean age of 21.03(SD 3.27)years,the prevalence of IGD was 15.23%(95%confidence interval:11.6%to 19.4%).In the correlational analysis,small to large(r:0.32-0.72)significant relationships between scores of IGD and other health outcomes were established.The indirect effect(B=0.300)via sleep quality accounted for 30.55%of the total effect(B=0.982)of IGD on perceived stress(partially mediated),while sleep quality(B=0.174)accounted for 27.93%of the total effect(B=0.623)of IGD on suicidal behaviour(partially mediated).The factors of being male,living in a single-parent family,using the internet for other than academic purposes(1-3 hours

关键词： behaviour internet media

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Ventral Hernia: An Innovative Grading System

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International Journal of Clinical Medicine 2022年第5期13卷 204-211页

作者： Fares Alghamdi mbbs—Independent Researcher Baljurashi Saudi Arabia

Background: Ventral hernia is a complex and progressive condition that may lead to serious complications. However, no specified grading or classifying system is found to categorize the hernia, which leads to clinical complexities and may affect the patient outcome. Aim: The general aim of this paper is to build up an easy and comprehensive grading system to categorize ventral hernia. Methodology: By carrying out a secondary search over clinical presentation, physical examination, and imaging studies of ventral hernia, a valid grading system is developed. Results: Hanoon’s grading system is composed of seven grades, grades 1, 2A, 2B, 3A, 3B, 3C, and 4. Each grade entailed different clinical presentations, imaging characteristics, and progressivity of ventral hernia. Conclusion: Hanoon’s grading system for ventral hernia can be used to solve the clinical complexities of ventral hernia. Also, it can be a step forward in hernia research to build upon.

关键词： General Surgery Hernia Classification Grading

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Primary Malignant Melanoma of Female Urethra:A Case Report and Review of Literature

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Journal of Oncology Research 2019年第3期1卷 13-16页

作者： Shashank Agrawal Tak GR Aditya Parikh Arvind Prakash Ganpule Abhishek Gajendra Singh Ravindra Bhalchandra Sabnis Mahesh Ramanlal Desai mbbs MSDNB(UROLOGY mbbs MSDNBMNAMS(Vice Chairman mbbs MSM.chDNB mbbs MSMch(Chairman mbbs MSFRCSFRCS(Medical Director

We report a very rare case report of female diagnosed with primary malignant melanoma.A 65 years old diabetic elderly postmenopausal female presented with a history of intermittent blood spots on undergarments for few days.Genital examination revealed a single,tan colored,soft chestnut size and polypoidal non ulcerated mass lesion protruding through the urethral meatus.Mass biopsy revealed poorly differentiated epithelial malignancy and immuno-histological analysis revealed positive with HMB 45 and protein S-100 suggestive of melanoma.Metastatic work up for the malignancy was negative.Complete urethrectomy with Mitrofanoff procedure with inguinal lymph node dissection was performed.Histopathological examination was suggestive of malignant melanoma of urethra.Here we discuss the clinicopathological features and management option possible in this scenario.

关键词： Female urethra melanoma

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Open reduction and internal fixation for displaced supracondylar fractures of the humerus in children with crossed K-wires via lateral approach

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Chinese Journal of Traumatology 2014年第3期17卷 130-135页

作者： Shahid Hussain Manzoor Ahmad Tufail Muzaffar Registrar Orthopedics SKIMS Medical College &Hospital Srinagar India Registrar Anaesthetist Hospital for Bone & JointSurgery Barzulla Srinagar India mbbs DNB physical Medicine and RehabilitationSrinagar India

有希望地在 children.MethodsWe 为肱骨的代替的 supracondylar 破裂经由侧面的途径与穿过的K电线估计开的减小和内部固定的治疗学的结果的目的跟随了与肱骨的 Gartland 类型 3 代替的 supracondylar 破裂介绍了并且被开的减小和内部固... 详细信息

有希望地在 children.MethodsWe 为肱骨的代替的 supracondylar 破裂经由侧面的途径与穿过的K电线估计开的减小和内部固定的治疗学的结果的目的跟随了与肱骨的 Gartland 类型 3 代替的 supracondylar 破裂介绍了并且被开的减小和内部固定与穿过的K电线管理经由的 52 个孩子侧面的 approach.There 是 37 男性和 15 个女病人；平均年龄是 7.39 年。当玩时，损伤的最普通的机制是秋天(n= ； 23 ) ，从高度到秋天列在后面(n= ； 20 ) ，道路交通事故(n= ； 5 ) 并且从承受高度的秋天(n= ； 2 ) 。在 2 种情况中，损害的模式不是可得到的。吝啬的后续是 12 个月，病人们根据 Flynn’s criteria.ResultsLateral 被估计途径提供了在二架紧张的飞机之间的侧面的列的一个优秀看法并且在所有情况中启用了解剖减小。在屈曲的 90 度或更多使肘不能调动不在生气 K 电线固定以后被需要。病人的多数在 6 星期大头针移动以内重获运动的完整的范围。二个病人有在大头针移动以后解决了的手术后的尺骨的神经损害。肘脉内翻足的普通迟了的复杂并发症没在任何病人被看见。推迟的表示到紧急情况部门，由有可食的油的骨头 setters 和按摩的重复操作为在 5 个病人的僵硬负责。表面的大头针道感染在 5 个病人被注意与调味品和抗菌素解决了。没有深感染发生了。详细临床的考试和 X 光线照相术的分析在最后的后续被做。他们包括了带运动的角度和范围的测量操作并且为比较的两上面的手足的正常方面，和拍。根据 Flynn’s 标准， 90.4% 病人证明为开的减小和肱骨的广泛地代替的 supracondylar 破裂的内部固定的令人满意的 results.ConclusionLateral 途径安全、直接，保证解剖减小和优秀功能。途径对在我们的安装的很矫形的外科医生容易、熟悉。

关键词：肱骨复位骨折儿童固定治疗内固定术道路交通事故平均年龄

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Advantages of Computed Tomography (CT) in Endoscopic Septopasty

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International Journal of Otolaryngology and Head & Neck Surgery 2020年第6期9卷 185-193页

作者： Md. Ashraful Islam Towsif Bin Mamoon Farid Uddin Milki Nazmul Hossain Chowdhury Saif Rahman Khan A. S. M. Rahman Tareq Mohammad mbbs FCPS FICS FRCS (Glasgow) Otolaryngology-Head & Neck Surgery Bangladesh Medical College Hospital Dhaka Bangladesh mbbs ENT Bangladesh Medical College Hospital Dhaka Bangladesh mbbs FCPS ENT Bangladesh Medical College Hospital Dhaka Bangladesh mbbs ENT National Institute of ENT Dhaka Bangladesh mbbs MCPS DLO MRCPS (Glasgow) Bangladesh Medical College Hospital Dhaka Bangladesh

Background and objective: Nasal obstruction is the most frequent presentation to the otolaryngologist all over the world. Symptoms are multisystem involvement such as headache, epistaxis, ophthalmological, otological, upper and lower respiratory tract infections;and many more. Septoplasty is commonly performed for nasal septal deviation as a primary indication of nasal airway obstruction. Physical examination, anterior rhinoscopy and nasal endoscopy are considered the gold standard for detecting septal deviation. Computed tomography (CT) can also be used to evaluate the nasal septum, anatomical variants and unveils the associated sinonasal diseases. This study aimed to find out the advantages of CT in endoscopic septoplasty for all out benefits to the patients. Patients and methods: 168 patients of nasal septal deviation were selected from 2015 to 2018 in the Bangladesh Medical and Popular Medical College Specialized Hospital. Age ranged between 10 years to 70 years of age. CT scanning in both coronal, axial and sagittal sections had been done in all patients after proper history taking, physical examination, anterior rhinoscopy and nasal endoscopy. Endoscopic septoplasty alone and/or other ancillary procedures were performed in all 168 patients under general anesthesia. Results: Amongst 168 patients, male was 116 (69%) and female was 52 (31%) with a ratio 2.2:1. Maximum 58 (35%) reported in 31 to 40 years and 48 (29%) was found in 21 to 31 years of age. Hypertrophied inferior turbinate (HIT) 54 (32%) and 48 (29%) concha bullosa (CB) were associated with 168 septal deviation. Associated pathologies like maxillary antral cyst 68 (40%) and maxillary sinusitis 62 (37%) were documented. Conclusion: CT scanning unveils the abnormal anatomic variants and associated sinonasal pathologies along with nasal septal deviation. Endoscopic septoplasty, correction of the anatomical variants and complete surgical clearance of the sinonasal pathologies can give t

关键词： Computed Tomography Endoscopic Septoplasty Advantage

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Awareness, Knowledge, Perception and Attitude towards Prescription Medicines Abuse among Medicines Prescribers and Dispensers in Nnewi Nigeria

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Pharmacology & Pharmacy 2015年第5期6卷 254-266页

作者： Prosper Obunikem Uchechukwu Adogu Ifeoma A. Njelita Nonye Bibiana Egenti Chika Florence Ubajaka Ifeoma A. Modebe Consultant Public Health Physician (mbbs FWACP FMCPH) Department of Community Medicine NAU/NAUTH Nnewi Nigeria Consultant Public Health Physician (MBBS MPH FWACP) Department of Community Medicine NAUTH Nnewi Nigeria Consultant Public Health Physician (mbbs MPH FMCPH) Department of Community Medicine University of Abuja Abuja Nigeria Consultant Public Health Physician (mbbs FMCPH) Department of Community Medicine NAU/NAUTH Nnewi Nigeria Consultant Public Health Physician (mbbs FWACP) Department of Community Medicine NAU/NAUTH Nnewi Nigeria

Background: Abuse of medicines is becoming a serious problem in many parts of the world, with negative consequences ranging from addiction, psychosis, cardiovascular complications, and premature deaths from unintentional overdose. Objectives: The objective of this study is to assess awareness, knowledge, perception and attitudes toward the abuse of prescription medicines (PM) among medicines prescribers and dispensers in Nigeria. Design and Participants: A descriptive cross-sectional study was carried out among pharmacists, other pharmacy staff in retail pharmacies, licensed patent medicines vendors (chemical sellers), and medical doctors in Nnewi, Nigeria. Data were collected through self-completed questionnaire supervised by trained research assistants, between December 2013 and April 2014. Three hundred and seventy-five participants were recruited for this study. Data Analysis: The Statistical Package for the Social Sciences (SPSS) version 17 for windows was used for data analysis. Bivariate and multivariate analyses were carried out to evaluate differences and associations based on selected variables. Results: The perception was high 294 (78.4%) among respondents that PM abuse was a problem in the community. Knowledge of health problems associated with PM abuse was also high at 226 (60.3%). However the attitude of the respondents towards early detection of PM abuse among their patients/clients was discouraging. Education, educational status, work status and gender significantly predict good knowledge and positive attitude about PM abuse. Conclusion: Findings from this study will assist health authorities to formulate appropriate health promotion interventions to control and prevent abuse of prescription medicines. Actions directed at early intervention, capacity building, education, public health initiatives and law enforcements will hopefully curb the menace of PM abuse in Nnewi, Nigeria.

关键词： Prescription Medicine Abuse Knowledge Attitude Nnewi Nigeria

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Treatment of Multiple Sclerosis

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Neuroscience & Medicine 2016年第2期7卷 74-82页

作者： M. Nadeem O. Mufti I. Ahsan R. Naheed S. M. Faheem Muhammad Nadeem mbbs SUNY Buffalo NY USA Owais Mufti MD SUNY Buffalo NY USA Irfan Ahsan MD Abington Memorial Hospital Abington PA USA Rabia Naheed mbbs Fatima Memorial Hospital Lahore Pakistan Sheikh Muhammad Faheem mbbs University of IOWA Hospital Iowa City IA USA

Background: A new method of immune-based therapies has been made and applied on multiple sclerosis patients in last decades. Some of these treatments have a high efficacy and reasonable side effects. In slowing disease progression, present treatments have significant limitations, but often associated with significant adverse effects of immunosuppression, with having a bit low capability to counter the disability. Methods: This is a review meta-analysis of treatment of multiple sclerosis. Results: Thus a valuable aim for multiple sclerosis clinical research is to introduce more effective therapies. Conclusion: It is absolutely necessary to increase the individualized therapy planes development in respect to make better planes to disease-modifying treatments.

关键词： Immune Sequestration Multiple Sclerosis Non-Specific Immune Modulation Lymphocyte-Targeted Therapy

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Minimally Invasive Hind-Foot Fusion in Charcot Patients

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Open Journal of Orthopedics 2023年第11期13卷 477-484页

作者： Sami Nogdallah Mohanad Osman Ibrahim Abd-Elseed Alaa Mohamed Mohamed Khairy Osama Gamal Nubi Montaser Fatooh Hozifa Mohammed Ali Abd-Elmaged Department of Orthopedics Alneelain University Khartoum Sudan Department of Orthopedics Orthopaedic Registrar Sudan Medical Specialization Board Khartoum Sudan Department of Orthopedics Bashaer University Hospital MBBS Al Neelan University Khartoum Sudan Department of Orthopedics Alzaiem Alazhari University Khartoum Sudan

Background: Hindfoot fusion, is a fusion of the talonavicular, talocalcaneal, and calcaneocuboid joints and is commonly performed for patients complaining of pain, chronic instability and gross deformity as a result of hindfoot pathology. Objective: This study aimed to assess the functional outcomes of the patients underwent hindfoot fusion, the post-operative complications and patient’s satisfaction. Methodology: This study is a prospective cohort study was conducted in Future hospital, in Khartoum, Sudan. It involved 30 patients from July 2015-July 2022. Data was collected by the primary researcher using data collection sheet, then it was cleaned and entered into Microsoft excel data sheet and was analysed using SPSS version 28 software. Results: 33.3% of the patients are aged 51 - 60 years, and >60 years. Male: Female equals 1:1. 56.7% are for the left side, only 23.3% developed complications. 63.3% patients are fully satisfied. There is a significant correlation between the AOFAS score before and after the operation. Also, a significant correlation between the means of AOFAS score after with the complications and the satisfaction of the patients. Conclusion: Minimally invasive tibio-talo-calcaneal is an alternative procedure for the treatment of severe Charcot arthropathy of the ankle. The expected functional outcome is impressive and comparable with the open surgery. However, the post-operative complications are prevalent in 23.3% of patients. Most candidates are fully satisfied with the procedure.

关键词： Ankle Sudan Patient Satisfaction Arthropathy Neurogenic

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The Radiological Outcome of Surgical Correction of Hallux Valgus with Combined Scarf and Akin Osteotomies

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Open Journal of Orthopedics 2023年第3期13卷 84-96页

作者： Sami Nogdallah Mohamed Alhassan Osman Montaser Fatooh Alaa Mohamed Mohamed Khairy Hozifa Mohammed Ali Abd-Elmaged Osama Gamal Nubi Orthopedics Surgery Department Alneelain University Khartoum Sudan Bashaer Teaching Hospital Khartoum Sudan Orthopaedic Registrar Sudan Medical Specialization Board Khartoum Sudan Orthopedics Surgery Department Alzaiem Alazhari University Khartoum Sudan Bashaer University Hospital MBBS Al Neelan University Khartoum Sudan

Background: Hallux valgus deformity is one of the most common chronic and progressive foot deformities. Surgical correction of the deformity plays a central role in the treatment of symptomatic hallux valgus. However, more than one hundred different surgical techniques have been described. Objective: To assess the radiological outcome of hallux valgus surgical correction using a scarf and akin osteotomies. Materials and methods: A cross-sectional hospital-based study was conducted on 25 adult patients (36 feet). Twenty-two females and two males with hallux valgus were treated with surgical correction using a scarf and akin osteotomies. All candidates were kept on regular postoperative, scheduled clinical follow-up programs for one year and assessed radiologically. Results: Twenty-five patients (36 feet) were included in this study. The hallux valgus angle significantly shifted to the normal range (less than 15°) after surgery, and the inter-metatarsal angle also improved to the normal range (less than 9°). Conclusion: Using scarf and akin osteotomies in treating moderate and severe hallux valgus deformity provides the satisfactory radiological outcomes in form of decreasing hallux valgus angle and inter-metatarsal angle.

关键词： Hallux Valgus Scarf Osteotomy Akin Osteotomy Valgus Angle Intermetatarsal Angle

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Central nervous system recurrence in a patient treated for acute promyelocytic leukemia,resulting in sideroblastic anemia:A case report

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World Journal of Hematology 2022年第1期9卷 1-5页

作者： Haroon Nawaz Ayesha Choudhry William Joseph Morse Department of Internal Medicine Westside Regional Medical CenterPlantationFL 33324United States mbbs Fatima Jinnah Medical UniversityMozang ChungiLahore 54000PunjabPakistan Clinical Medical Student Ross University School of MedicineMiramarFL 33027United States

BACKGROUND Previous cases that have been stated in this article have displayed that around 1%to 7%of patients that have been treated with chemotherapy for acute promyelocytic leukemia developed myelodysplastic syndrome or acute myeloid leukemia.One can see that’s why this case presentation of a 60-year-old man that had a good response to acute promyelocytic leukemia treatment,that later presented with a central nervous system recurrence of acute promyelocytic leukemia and acquired sideroblastic anemia(a form of myelodysplasia)from treatment is a unique case report.CASE SUMMARY The presence of central nervous system relapse in acute promyelocytic leukemia patients is very unlikely compared to recurring mainly in the bone marrow.It is also uncommon to be diagnosed with sideroblastic anemia(form of myelodysplastic syndrome)as a result from treatment for acute promyelocytic leukemia.This case report highlights the detection,treatment/maintenance with idarubicin,all-trans-retinoic-acid,arsenic trioxide,methotrexate,6-mercaptopurine,and ommaya reservoir intrathecal methotrexate administration in a patient that had central nervous system relapse of acute promyelocytic leukemia and acquired sideroblastic anemia.CONCLUSION In essence,first time relapse concerning the central nervous system in treated acute promyelocytic leukemia patients who had a good response to therapy is very uncommon.The acquirement of a myelodysplastic syndrome such as ringed sideroblastic anemia is also rare regarding this patient population.Although such cases are infrequent,this case report represents a unique insight of the detection,treatment,and maintenance of a 60-year-old man diagnosed with acute promyelocytic leukemia,resulting in the acquirement of sideroblastic anemia and central nervous system relapse.

关键词： Acute promyelocytic leukemia Central nervous system relapse Sideroblastic anemia All-transretinoic acid Myelodysplasia Case report

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