检索结果-南通市图书馆

The formation and growth mechanisms of young back-arc spreading ridges from high-resolution bathymetry:The Marsili Seamount(Tyrrhenian Sea,Italy)

在线全文

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第1期15卷 325-338页

作者： eugenio Nicotra Salvatore Passaro Guido Ventura Dipartimento di Biologia ecologia e Scienze della Terra Universitàdella Calabria87036 Arcavacata di RendeCosenzaItaly Istituto di Scienze Marine CNR 80133 NapoliItaly Istituto Nazionale di Geofisica e Vulcanologia 00143 RomaItaly Istituto per lo studio degli impatti Antropici e Sostenibilitáin ambiente marino CNR 91026 Capo GranitolaTrapaniItaly

The formation and growth mechanisms of Mid-Ocean Ridges(MOR)are relatively well known,whereas those of back-arc spreading ridges are comparatively less known because geophysical,geochemical,and morphological data are scarce and of low *** we present a high-resolution bathymetry of the Marsili Seamount(MS;1 Ma-3 ka),which represents the inflated spreading ridge of the 2 Ma old Marsili back-arc basin associated to the subduction of the Ionian Sea below the Calabrian Arc and Tyrrhenian *** is 70 km long,30 km wide,and its height reaches about 3000 m from surrounding *** new digital bathymetric model has a 5 m grid cell size resolution and covers the MS bathymetry from-1670 mbsl to the top at-491 *** conduct morphometric and morphological analyses of the bathymetry and recognize landforms due to volcanic,tectonic,hydrothermal and gravity *** consists of volcanoes related to fissural and central-type activity,this latter located at the northern and southern tips of the main dike *** swarms represent the surface expression of different ridge segments whose strikes are controlled by the larger scale back-arc spreading processes and by the local occurrence of an active hydrothermal *** latter develops in a flat area between two partly overlapping ridge segments where historical volcanism and extensional processes *** ridges represent the embryonic stage of the formation of transform-like *** volcanoes,the northern of which is characterized by a caldera,form at the tips of MS because the decrease in width of the major volcanic fissures promotes vent localization associated with the formation of sill-like reservoirs from which central-type vents may *** processes affecting the MS flanks are due to shallow seafloor *** collapses affecting the northernmost central-type polygenic volcano must be included in the evaluation of the hazard related to potential *** dipping faul

关键词： Back-arc spreading ridge Morphology Tectonics Volcanism Marsili seamount

穿越味蕾汉堡Le big TamTam美食市场

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

室内设计与装修 2024年第10期 8-13页

作者： coco(译) Nicolo Lanfranchi(摄影) Martin Kunze Hamburg(摄影) 无不详 studio aisslinger

近日,德国著名的建筑和设计工作室aisslinger完成了汉堡新旗舰美食市场Le big Tam Tam的室内设计。在4年的时间里,aisslinger工作室与汉堡Tellerrand咨询有限公司合作,为汉堡第一家列入遗产名录的购物中心Hanseviertel at Groβe Bleic... 详细信息

近日,德国著名的建筑和设计工作室aisslinger完成了汉堡新旗舰美食市场Le big Tam Tam的室内设计。在4年的时间里,aisslinger工作室与汉堡Tellerrand咨询有限公司合作,为汉堡第一家列入遗产名录的购物中心Hanseviertel at Groβe Bleichen开发了这个完美的美食世界。

关键词：设计工作室购物中心室内设计汉堡新旗舰

Chestnut tannin:New use,research and bioeconomy

在线全文

学校读者我要写书评

暂无评论

Journal of Bioresources and Bioproducts 2024年第3期9卷 246-252页

作者： Rosaria Ciriminna Francesco Meneguzzo Giovanna Li Petri Cosimo Meneguzzo Giuseppe Angellotti Mario Pagliaro Istituto per lo studio dei Materiali Nanostrutturati CNRvia U.La Malfa 15390146 PalermoItaly Istituto per la Bioeconomia CNRvia Madonna del Piano 1050019 Sesto Fiorentino(FI)Italy HyRes Srl via Salvator Rosa 1882100 BeneventoItaly

Chestnut tannin,extracted from the bark or wood of chestnut trees,possesses unique properties that make it valuable in various *** serves as a natural source of tannins,which are widely used in the production of leather,textiles,and wood *** research continues to explore its potential applications,chestnut tannin remains a promising resource with diverse industrial *** new use,research and bioeconomy aspects,this study provides a unified perspective on chestnut *** advanced applications will likely emerge shortly.

关键词： Tannin Chestnut Bioeconomy Tannin market Hydrolysable tannin

Cell metabolism pathways involved in the pathophysiological changes of diabetic peripheral neuropathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第3期19卷 598-605页

作者： Yaowei Lv Xiangyun Yao Xiao Li Yuanming Ouyang Cunyi Fan Yun Qian Department of Orthopedics Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Shanghai engineering Research Center for Orthopaedic Material Innovation and Tissue Regeneration ShanghaiChina Youth Science and Technology Innovation studio of Shanghai Jiao Tong University School of Medicine ShanghaiChina College of Fisheries and Life Science Shanghai Ocean UniversityShanghaiChina

Diabetic peripheral neuropathy is a common complication of diabetes *** the pathophysiological metabolic mechanism impels the generation of ideal ***,existing limited treatments for diabetic peripheral neuropathy expose the urgent need for cell metabolism *** the lack of comprehensive understanding of energy metabolism changes and related signaling pathways in diabetic peripheral neuropathy,it is essential to explore energy changes and metabolic changes in diabetic peripheral neuropathy to develop suitable treatment *** review summarizes the pathophysiological mechanism of diabetic peripheral neuropathy from the perspective of cellular metabolism and the specific interventions for different metabolic pathways to develop effective treatment *** metabolic mechanisms(e.g.,polyol,hexosamine,protein kinase C pathway)are associated with diabetic peripheral neuropathy,and researchers are looking for more effective treatments through these pathways.

关键词： cell metabolism diabetic peripheral neuropathy peripheral nerve injury protein kinase C pathway reactive oxygen species.

Heat Loss from Buried Vertical Plate with Assigned Temperature Distribution

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2009年第3期18卷 253-255页

作者： L.Fontana A.Quintino Dipartimento di Progettazione e studio dell'Architettura Universita degli Studi"Roma Tre" Dipartimento

Thermal losses for a buried vertical thin plate can be expressed as a function of the assigned temperature distribution,the medium conductivity and the geometrical properties that describe the model. When the geometricalproperties reduce to one, the plate-ground thermal resistance can be expressed regardless of plate dimension, dependingonly on temperature distribution given at surface plate and its temperature difference with medium.

关键词： thermal resistance buried vertical plate

Circulating and stool nucleic acid analysis for colorectal cancer diagnosis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第4期20卷 957-967页

作者： Giulia De Maio Claudia Rengucci Wainer Zoli Daniele Calistri Biosciences Laboratory Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS

In recent years, the need to identify molecular markers characterized by high sensitivity and specificity in detecting and monitoring early and colorectal cancer lesions has increased. Up to now, none of the markers or panels of markers analyzed have met the rigorous standards required of a screening program. The important discovery of circulating nucleic acids in biological fluids has aroused intense scientific interest because of their usefulness in malignant and non malignant diseases. Over time, their yield and stability have been identified and compared with other “standard” biomarkers. The analysis of circulating DNA from blood and stool is a relatively simple and non-invasive procedure, representing a very attractive marker to detect genetic and epigenetic mutations and to monitor disease progression. A correlation between blood and stool biomarkers could also help to enhance currently available diagnostic approaches. However, various processing and analytic problems need to be resolved before such an approach can be applied in clinical practice.

关键词： Colorectal cancer Circulating DNA Circulating RNA early diagnosis DNA integrity

Highly efficient and automated extraction of DNA from human remains using a modified eZ1 protocol

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forensic Sciences Research 2021年第1期6卷 59-66页

作者： Anna Barbaro Sasha Samar Giacomo Falcone Angelo La Marca Department of Forensic Genetics Studio Indagini Mediche E Forensi(SIMEF)Reggio CalabriaItaly

Bones and teeth often represent the only sources of DNA available for identifying human *** in bones and teeth is generally better preserved than that in soft tissues because of the presence of hard connective tissue with a high level of *** of the extensive mineralisation,the choice of an efficient DNA extraction procedure is important to minimise the sampling of a high level of minerals and to remove polymerase chain reaction(PCR)*** protocols are available for DNA extraction from bones and teeth as part of the Qiagen eZ1 DNA Investigator Kit using the eZ1 Advanced XL automated purification *** improve the efficiency of DNA extraction from skeletal remains,the present study focuses on a modification to these already available *** this study,different bones and teeth collected between 1 and 50 years after death were subjected to DNA extraction using the standard eZ1 protocol,a supplementary protocol,and a modified *** modified approach included a decalcification step,whereas the Qiagen protocols worked directly on non-decalcified *** all three procedures,150 mg samples were used for DNA *** evaluated the quantity of DNA recovered from samples,the presence of any PCR inhibitors co-extracted,the level of DNA degradation,the quality of short tandem repeat(STR)profiles,and the reproducibility of the modified *** compared with the other protocols,the modified protocol resulted in the best recovery of DNA that was free of PCR ***,the STR profiles were reliable and of high *** our opinion,the decalcification step increases DNA recovery by softening tissues,which allows lysis solutions to act more ***,the use of two lysis solutions and the variation added to the eZ1 purification step allow for DNA recovery with quality and quantity superior to those of the previously available Qiagen-based *** findings may be helpful solutions to t

关键词： Forensic sciences forensic genetics DNA extraction bone tooth eZ1 automation

Aeromonas veronii biovar veronii and sepsis-infrequent complication of biliary drainage placement: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第6期7卷 759-764页

作者： Manlio Monti Arianna Torri elena Amadori Alice Rossi Giulia Bartolini Chiara Casadei Giovanni Luca Frassineti Department of Medical Oncology Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS Unit of Microbiology Wide Catchment Area of Romagna Laboratory Radiology Unit Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS

BACKGROUND Aeromonas species are uncommon pathogens in biliary sepsis and cause substantial mortality in patients with impaired hepatobiliary function. Asia has the highest incidence of infection from Aeromonas,whereas cases in the west are *** SUMMARY We report the case of a 64-year-old woman with advanced pancreatic cancer and jaundice who manifested fever,abdominal pain,severe thrombocytopenia,anemia and kidney failure following the insertion of a percutaneous transhepatic biliary drainage. Blood culture results revealed the presence of Aeromonas veronii biovar veronii(A. veronii biovar veronii). After antibiotic therapy and transfusions,the life-threatening clinical conditions of the patient improved and she was *** This was a rare case of infection,probably the first to be reported in West countries,caused by A. veronii biovar veronii following biliary drainage. A finding of Aeromonas must alert clinician to the possibility of severe sepsis.

关键词： Aeromonas veronii biovar veronii Aeromonas Pancreatic cancer Cholangitis Sepsis Biliary tract infection Case report

Natural killer cells activity in a metastatic colorectal cancer patient with complete and long lasting response to therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2017年第11期5卷 390-396页

作者： Alessandro Ottaiano Maria Napolitano Monica Capozzi Salvatore Tafuto Antonio Avallone Stefania Scala Department of Abdominal Oncology Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione Giovanni Pascale" - I.R.C.C.S. Immunology Unit Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione Giovanni Pascale" - I.R.C.C.S.

Here we report a case of a 70-year-old man who received adjuvant chemotherapy with fluorouracile, folinic acid and oxaliplatin after a left hemicolectomy for a stage Ⅲb adenocarcinoma in May 2009. During followup he de-veloped abdominal lymphnodes metastases evidenced by positron emission tomography-computed tomography(PeT-CT) scan and increase of carcinoembryonic antigen(CeA) level. Chemotherapy with capecitabine, oxaliplatin and bevacizumab was started in April 2012. Restaging showed a complete response and normalization of CeA. The patient received maintenance therapy with bevacizumab which was stopped in December 2013 for patient choice. In October 2014, a new increase in CeA was documented and PeT-CT scan showed lung metastases. Analysis of RAS status revealed the absence of mutations, then the patient started a second-line chemotherapy with fluorouracile, folinic acid, irinotecan(folfiri) and panitumumab achieving, in January 2015, a complete response and normalization of CeA. Thereafter, folfiri was discontinued for toxicity; furthermore, upon the third occurrence of a grade 3 dermatologic toxicity, panitumumab was continued from June 2015 at 60% of the original dose and it was administered every three weeks. Until presentation of this case, the patient maintains a complete response, has no symptoms of disease and CeA is normal. Interestingly, this patient presented a high proportion of circulating natural killer(NK) cells(35.1%) with high cytotoxic activity against tumor cells. Study on the role of NK in patients with advanced colorectal cancer are ongoing.

关键词： Colorectal cancer Panitumumab Natural killers Regulatory cells Chemotherapy