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In‑depth proteome characterization of endometrium and extraembryonic membranes during implantation in pig

Journal of Animal Science and Biotechnology 2024年第3期15卷 1027-1055页

作者： Maria A.Gil Josep M.Cambra Heriberto Rodriguez‑Martinez Cristina Cuello Inmaculada Parrilla Emilio A.Martinez Department of Medicine and Animal Surgery International Excellence Campus for Higher Education and Research“Campus Mare Nostrum”University of MurciaMurciaSpain Institute for Biomedical Research of Murcia(IMIB-Pascual Parrilla) MurciaSpain Technical university of Munich MunichGermany Department of Biomedical&Clinical Sciences(BKV) BKH/Obstetrics&GynaecologyLinkoping UniversityLinkopingSweden

Background Proteome characterization of the porcine endometrium and extraembryonic membranes is important to understand mother-embryo *** this study,the proteome of the endometrium and cho-rioallantoic membrane was characterized in pregnant sows(PS)during early gestation(d 18 and 24 of gestation)and in the endometrium of non-pregnant sows(NPS)during the same days using LC-MS/MS *** UniProtKB database and ClueGO were used to obtain functional Gene Ontology annotations and biological and functional networks,*** Our analysis yielded 3,254 and 3,457 proteins identified in the endometrium of PS and NPS,respectively;of these,1,753 being common while 1,501 and 1,704 were exclusive to PS and NPS,*** addition,we iden-tified 3,968 proteins in the extraembryonic membranes of *** analyses of function revealed some proteins had relevance for the immune system process and biological adhesion in endometrium while the embryonic chorion displayed abundance of proteins related to cell adhesion and cytoskeletal organization,suggesting they dominated the moment of endometrial remodeling,implantation and adhesion of the lining *** are available via Pro-teomeXchange with identifier *** This is the first in-depth proteomic characterization of the endometrium and extraembryonic mem-branes during weeks 3 to 4 of gestation;data that contribute to the molecular understanding of the dynamic environ-ment during this critical period,associated with the majority of pregnancy losses.

关键词： Endometrium Extraembryonic membranes Implantation Pig Proteome

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The function of doping nitrogen on removing fluoride with decomposing La-MOF-NH_2:Density functional theory calculation and experiments

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Journal of Environmental Sciences 2024年第1期135卷 118-129页

作者： Hongguo Zhang KuilinWan Jia Yan Qian Li Yufang Guo Lei Huang Samuel Raj Babu Arulmani Jian Luo School of Environmental Science and Engineering Guangzhou UniversityGuangzhou 510006China Guangzhou university-linkoping university Research Center on Urban Sustainable Development Guangzhou UniversityGuangzhou 510006China School of Civil and Environmental Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

Fluoride is an important pollutant in wastewater,and adsorption is an effective way to remove *** nitrogen plays an important role in adsorbent materials,computational models were developed to understand the changes in work function resulting from nitrogen ***-N-C-800℃,was prepared by pyrolyzing La-MOF-NH_(2)to verify the influence on the performance of removing fluoride by *** and electrochemical performance tests were performed to characterize La-N-C-800℃.Adsorption kinetics,adsorption thermodynamics,initial concentrations,pH,and ions competition were investigated using La-N-C-800℃for fluoride *** addition,density functional theory was applied to evaluate the function of *** nitrogen atoms were added,the density of states,partial density of states,populations,and different orbits of charge were calculated to discover deep *** strengthened the carbon structure and La_(2)O_(3)structure to remove *** addition,nitrogen can also act as an adsorption site in the carbon *** results provide design ideas for improving the performance of adsorbent materials by doping elements.

关键词： Capacitive deionization Fluoride La-MOFs Doping nitrogen

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Oxidation behavior of Ni-based superalloy GH4738 under tensile stress

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Rare Metals 2024年第8期43卷 3913-3920页

作者： Ji-Chong Hu Hai-Liang Huang Chong-Chong Wu Xiao-Yu Sun Jie Wang Yan-Hong Yang Jing-Long Qu Liang Jiang Jin-He Dou Yang Chen Institute for Advanced Studies in Precision Materials Yantai UniversityYantai 264005China Department of Management and Engineering Linkoping University58183LinkopingSweden Shi-Changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang110016China Gaona Aero Material Co. LtdBeijing 100081China College of Artificial Intelligence and Big Data Shandong First Medical University and Shandong Academy of Medical SciencesJinan250117China

Revealing the oxidation behavior of superalloys is crucial for optimizing material properties and extending service *** study investigated the oxidation behavior of superalloy GH4738 under stress states at 850℃.High-throughput specimens were fabricated to withstand different stresses at the same *** oxidation s amples were analyzed using the mass gain method to obtain oxidation kinetic *** results show that the external stress below 200 MPa could improve the oxidation resistance of the *** tensile stress increasing,the oxide layer becomes thinner,denser and more complete,while internal oxidation *** tensile stress alters the structure of the external oxide layer from a two-layer to a threelayer *** Cr_(2)O_(3) oxide layer inhibits the outward diffusion of Ti,leading to Ti enrichment at the oxide-matrix interface and altering the oxidation mechanism of GH4738.

关键词： Ni-based Superalloy Oxidation behavior Tensile stress Oxide layer

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Comparative efficacy and optimal duration of first-line antibiotic regimens for acute otitis media in children and adolescents:a systematic review and network meta-analysis of 89 randomized clinicaltrials

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World Journal of Pediatrics 2024年第3期20卷 219-229页

作者： Min Seo Kim Jae Han Kim Seohyun Ryu Seung Won Lee Dong Keon Yon Eunyoung Kim Ai Koyanagi Elena Dragioti Jae Il Shin Lee Smith Samsung Advanced Institute forHealth Sciences&Technology(SAIHST) Samsung Medical CenterSungkyunkwan UniversitySeoulRepublic of Korea Yonsei university Collegeof Medicine SeoulRepublicof Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonRepublic of Korea Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulRepublic of Korea Evidence-Based Research Laboratory Department of Clinical Pharmacy and Pharmaceutical CareCollege of PharmacyChung-Ang UniversitySeoulRepublic of Korea Parc Sanitari Sant Joan de Deu/CIBERSAM/ISCIII Universitat de BarcelonaFundacio Sant Joan de Déu.Sant Boi de LlobregatBarcelonaSpain ICREA Pg.Lluis Companys 23BarcelonaSpain Pain and Rehabilitation Centre and Department of Medical and Health SciencesLinkoping University58185 LinkopingSweden Department of Pediatrics Yonsei University College of MedicineYonsei-ro 50Seodaemun-gu8044Seoul 03722Republic of Korea Centre for Health Performanceand WellbeingAnglia Ruskin UniversityCambridge CB11PTUK Research Laboratory Psychology of Patients Families&Health ProfessionalsDepartment of NursingSchool of Health SciencesUniversity of IoanninaIoannina 45500Greece

Introduction Antibiotic use for acute otitis media(AOM)is one of the major sources of antimicrobial ***,the effective minimal antibiotic duration for AOM remains ***,guidelines often recommend broad ranges(5-10 days)of antibiotic use,yet the clinical impact of such a wide window has not been *** We systematically searched PubMed/MEDLINE,Embase,Scopus,Web of Science,and Cochrane Library from database inception to 6 October *** meta-analysis was conducted on randomized controlled trials that assessed antibiotic treatment for AOM in children(PROSPERO CRD42020196107).Results For amoxicillin and amoxicillin-clavulanate,7-day regimens were noninferior to 10-day regimens in clinical responses[amoxicillin:risk ratio(RR)0.919(95%CI 0.820-1.031),amoxicillin-clavulanate:RR 1.108(0.957-1.282)],except for≤2 *** the third-generation cephalosporins,7-day and 10-day regimens had similar clinical responses compared to placebo[7-day:RR 1.420(1.190-1.694),10-day:RR 1.238(1.125-1.362)compared to placebo].However,5-day regimens of amoxicillin-clavulanate and third-generation cephalosporins were inferior to 10-day *** to amoxicillin,a shorter treatment duration was tolerable with *** Our findings indicated that 1O days of antibiotic use may be unnecessarily long,while the treatment duration should be longer than 5 ***,5-day regimens would be sufficient for a modest treatment *** findings revealed that the current wide range of recommended antibiotic durations may have influenced the clinical outcome of AOM,and a narrower antibiotic duration window should be re-established.

关键词： Amoxicillin-potassium Amoxicillin Antibacterial agents Cephalosporins Duration of therapy

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Revisiting Total Model Errors and Model Validation

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Journal of Systems Science & Complexity 2021年第5期34卷 1598-1603页

作者： LJUNG Lennart linkoping university Sweden

The paper contains a discussion of earlier work on Total Model Errors and Model *** is maintained that the recent change of paradigm to kernel based system identification has also affected the basis for(and interest i... 详细信息

关键词： Bias kernel methods model errors regularization system identification variance

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Nanocontacts give efficient hole injection in organic electronics

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Science Bulletin 2021年第9期66卷 875-879,M0003页

作者： Qingzhen Bian Chiara Musumeci Chuanfei Wang reas Skallberg Yongzhen Chen Zhangjun Hu EPeter Münger Kajsa Uvdal Mats Fahlman Olle Inganas Biomolecular and Organic Electronics Department of PhysicsChemistry and BiologyLinkoping UniversitySE-58183 LinkopingSweden Laboratory of Organic Electronics Department of Science and TechnologyLinkoping University60174 NorrkopingSweden Molecular Surface Physics and Nano Science Department of PhysicsChemistry and BiologyLinkoping UniversitySE-58183 LinkopingSweden Department of Physics Chemistry and BiologyLinkoping UniversitySE-58183 LinkopingSweden

A key requirement for well performing devices based onorganic semiconductors is to ensure ohmic contacts, where anefficient hole and electron injection and extraction can beachieved at the electrode/semiconductor interfaces. The usualway to obtain ohmic contacts involves fine tuning of the energet-ics at the interfaces by using dopants (p- type and n-type) to con-trol the Fermi level of the semiconductor [1,2], or using suitablemetals or metal oxides as electrodes [3].

关键词：有机发光二极管场效应晶体管空穴注入有机电子器件欧姆接触导电聚合物新型材料传输材料

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Characterization of Magnetron Sputter CN_(x) Thin Films

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Chinese Physics Letters 1998年第2期15卷 120-122页

作者： ZHENG Wei-tao J.E.Sundgren Department of Materials Science Jilin UniversityChangchun 130023 Department of Physics Linkoping UniversityS-58183 LinkopingSweden

Carbon nitride thin films were deposited at different substrate temperature(ST)by using reactive magnetron sputtering in a pure N_(2) discharge,and studied by laser Raman spectroscopy,x-ray photoelectron spectroscopy(XPS),and spectroscopic *** Raman spectra of the films show that I(D)/I(G)decreased with the increase of *** D bandposition shifted towards lower frequency,while the G bandposition shifted towards higher frequency as the ST *** XPS data exhibit that Nls binding states also depend on *** optical band gap of the films is found dropped from 0.22eV to 0.10eV with the increase of ST.

关键词： shifted films spectroscopic

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Diffusivity-limited q-space trajectory imaging

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Magnetic Resonance Letters 2023年第2期3卷 187-196,I0005页

作者： Deneb Boito Magnus Herberthson Tom Dela Haije Ida Blystad Evren Ozarslan Department of Biomedical Engineering Campus USLinkoping UniversityLinkopingSE-58183.Sweden Center for Medical Image Science and Visualization Linkoping UniversityLinkopingSE-58183Sweden Department of Mathematics Linkoping UniversityLinkopingSE-58183Sweden Department of Computer Science University of CopenhagenCopenhagenDK-2300Denmark Department of Radiology in linkoping and Department of Health Medicine and Caring SciencesLinkoping UniversityLinkopingSE-58183Sweden

Q-space trajectory imaging(QTI)allows non-invasive estimation of microstructural features of heterogeneous porous media via diffusion magnetic resonance imaging performed with generalised gradient waveforms.A recently proposed constrained estimation framework,called QTI+,improved QTI's resilience to noise and data sparsity,thus increasing the reliability of the method by enforcing relevant positivity *** this work we consider expanding the set of constraints to be applied during the fitting of the QTI *** show that the additional conditions,which introduce an upper bound on the diffusivity values,further improve the retrieved parameters on a publicly available human brain dataset as well as on data acquired from healthy volunteers using a scanner-ready protocol.

关键词： Diffusion Diffusion MRI q-space trajectory imaging QTI Microstructure Microscopic anisotropy QTI+ Constrained

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An overview of various control benchmarks with a focus on automotive control

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Control Theory and Technology 2019年第2期17卷 121-130页

作者： Lars ERIKSSON Vehicular Systems Department of Electrical EngineeringLinkoping UniversitySE-581 83 LinkopingSweden

There exists a gap between control theory and control practice,i.e.,all control methods suggested by researchers are not implemented in real systems and,on the other hand,many important in dustrial problems are not studied in the academic *** problems can help close this gap and provide many opportunities for members in both the controls theory and application *** goal is to survey and give pointers to different general controls and modeling related benchmark problems that can serve as inspiration for future benchmarks and then specifically focus the benchmark coverage on automotive control engineering *** the paper reflections are given on how different categories of benchmark designers,benchmark solvers and third part users can benefit from providing,solving,and studying benchmark *** paper also collects information about several benchmark problems and gives pointers to papers than give more detailed information about different problems that have been presented.

关键词： Benchmark automotive control robust control robotics engine control powertrain control system identification

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Phosphorus-doped Fe_(7)S_(8)@C nanowires for efficient electrochemical hydrogen and oxygen evolutions:Controlled synthesis and electronic modulation on active sites

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Journal of Materials Science & Technology 2021年第15期74卷 168-175页

作者： Thanh-Tung Le Xiao Liu Peijun Xin Qing Wang Chunyan Gao Ye Wu Yongjiang Zhangjun Hu Shoushuang Huang Zhiwen Chen School of Environmental and Chemical Engineering Shanghai UniversityShanghai200444China Department of Physics Chemistry and BiologyLinkoping UniversityLinkoping58183Sweden

Developing low-cost,efficient,and stable non-precious-metal electrocatalysts with controlled crystal structure,morphology and compositions are highly desirable for hydrogen and oxygen evolution ***,a series of phosphorus-doped Fe_(7)S_(8)nanowires integrated within carbon(P-Fe_(7)S_(8)@C)are rationally synthesized via a one-step phosphorization of one-dimensional(1D)Fe-based organicinorganic *** as-obtained P-Fe_(7)S_(8)@C catalysts with modified electronic configurations present typical porous structure,providing plentiful active sites for rapid reaction *** functional calculations demonstrate that the doping Fe_(7)S_(8)with P can effectively enhance the electron density of Fe_(7)S_(8)around the Fermi level and weaken the Fe-H bonding,leading to the decrease of adsorption free energy barrier on active *** a result,the optimal catalyst of P-Fe_(7)S_(8)-600@C exhibits a relatively low overpotential of 136 mV for hydrogen evolution reaction(HER)to reach the current density of 10 mA/cm^(2),and a significantly low overpotential of 210 mV for oxygen evolution reaction(OER)at 20 mA/cm^(2)in alkaline *** work presented here may pave the way to design and synthesis of other prominent Fe-based catalysts for water splitting via electronic regulation.

关键词： Ron sulfide P-doping Hydrogen and oxygen evolution reaction Electrocatalysis

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