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A novel transcription factor FnMYB4 regulates pigments metabolism of yellow leaf mutants in Fragaria nilgerrensis

Horticultural Plant Journal 2024年第5期10卷 1134-1150页

作者： Shu Jiang Yi Ji Jingyu Yue Mingqian Wang Yumeifeng Jia Li Xue Jiajun Lei College of Horticulture Shenyang Agricultural UniversityShenyangLiaoning 110866China

The strawberry species Fragaria nilgerrensis Schlechtendal ex ***,renowned for its distinctive white,fragrant peach-like fruits and strong disease resistance,is an exceptional research *** a previous study,an ethyl methane sulfonate(EMS)mutant library was established for this species,resulting in various yellow leaf *** yellowing materials are not only the ideal materials for basic studies on photosynthesis mechanism,chloroplast development,and molecular regulation of various pigments,but also have important utilization value in ornamental plants *** present study focused on four distinct yellow leaf mutants:mottled yellow leaf(MO),yellow green leaf(YG),light green leaf(LG),and buddha light leaf(BU).The results revealed that the flavonoid content and carotenoid-to-chlorophyll ratio exhibited a significant increase among these mutants,while experiencing a significant decrease in chlorophyll and carotenoid contents compared to the wild type(WT).To clarify the regulatory mechanisms and network relationships underlying these mutants,the RNA-seq and weighted gene coexpression network(WGCNA)analyses were *** results showed flavonoid metabolism pathway was enriched both in MO and YG mutants,while the chlorophyll biosynthesis pathway and carotenoid degradation pathway were only enriched in MO and YG mutants,***,key structural genes and transcription factors were identified on metabolic pathways of three pigments through correlation analyses and quantitative ***,a R2R3-MYB transcription factor,FnMYB4,was confirmed to be positively correlated with flavonoid synthesis through transient overexpression,virus-induced gene silencing(VIGS),and RNA interference(RNAi),accompanying by reoccurrence and attenuation of mutant ***,dual-luciferase(LUC)and yeast one-hybrid assays confirmed the binding of FnMYB4 to the FnFLS and FnF3H promoters,indicating that FnMYB4 positively regulates flavonoid sy

关键词： Fragaria nilgerrensis Mutant Leaf yellowing RNA-seq Flavonoid MYB

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Light axion-like particles and the pseudoscalar mesonic decays M→M′vv

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Communications in Theoretical Physics 2024年第9期76卷 37-41页

作者： Guo-Qiang Dai Chong-Xing Yue Yang-Yang Bu Yi-Hang Wang Department of physics Liaoning Normal UniversityDalian 116029China center for Theoretical and Experimental High Energy Physics Liaoning Normal UniversityDalian 116029China

The axion-like particle(ALP)is one kind of the best-motivated new *** consider its production from the pseudoscalar mesonic decays M→M′a,with M being a pseudoscalar meson B or *** upper limits on the flavor-conserving ALP–quark coupling parameter guare obtained by assuming the ALP to be an invisible *** find that the most severe constraint on gucomes from the decay K^(+)→π^(+)vv for 0.05 Ge V≤M_(a)≤0.35 Ge V,while the decays B^(+,0)→K^(+,0)vvand B^(+,0)→π^(+,0)υvcan also generate significant constraints.

关键词： axion-like particle pseudoscalar mesons branching ratios

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An Integrated External Archive Local Disturbance Mechanism for Multi-Objective Snake Optimizer

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Chinese Journal of Electronics 2024年第4期33卷 989-996页

作者： Leifu GAO Zheng LIU Institute for Optimization and Decision Analytics Liaoning Technical University

It is an interesting research direction to develop new multi-objective optimization algorithms based on meta-heuristics. Both the convergence accuracy and population diversity of existing methods are not *** paper proposes an integrated external archive local disturbance mechanism for multi-objective snake optimizer(IMOSO) to overcome the above shortcomings. There are two improved strategies. The adaptive mating between subpopulations strategy introduces the special mating behavior of snakes with multiple husbands and wives into the original snake optimizer. Some positions are updated according to the dominated relationships between the newly created individuals and the original individuals. The external archive local disturbance mechanism is used to re-search partial non-inferior solutions with poor diversities. The perturbed solutions are non-dominated sorting with the generated solutions by the next iteration to update the next external archive. The main purpose of this mechanism is to make full use of the non-inferior solution information to better guide the population evolution. The comparison results of the IMOSO and 7 state-of-the-art algorithms on WFG benchmark functions show that IMOSO has better convergence and population diversity.

关键词： Accuracy Sociology Metaheuristics Diversity methods Benchmark testing Statistics Convergence

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Quantifying Uncertainty in Dielectric Solids’ Mechanical Properties Using Isogeometric Analysis and Conditional Generative Adversarial Networks

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2587-2611页

作者： Shuai Li Xiaodong Zhao Jinghu Zhou Xiyue Wang College of Civil Engineering&Architecture Dalian UniversityDalian116622China Research center for Geotechnical and Structural Engineering Technology of liaoning Province Dalian UniversityDalian116622China

Accurate quantification of the uncertainty in the mechanical characteristics of dielectric solids is crucial for advancing their application in high-precision technological domains,necessitating the development of robust com-putational *** paper introduces a Conditional Generation Adversarial Network Isogeometric Analysis(CGAN-IGA)to assess the uncertainty of dielectric solids’mechanical *** is utilized for the precise computation of electric potentials in dielectric,piezoelectric,and flexoelectric materials,leveraging its advantage of integrating seamlessly with Computer-Aided Design(CAD)models to maintain exact geometrical *** CGAN method is highly efficient in generating models for piezoelectric and flexoelectric materials,specifically adapting to targeted design requirements and ***,the CGAN-IGA is adopted to calculate the electric potential of optimum models with different parameters to accelerate uncertainty quantification *** accuracy and feasibility of this method are verified through numerical experiments presented herein.

关键词： Dielectric solid isogeometric finite element method surrogate model generative adversarial

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On the Infinite-Dimensional Modular Lie Superalgebras of O-Type

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Algebra Colloquium 2024年第2期31卷 347-360页

作者： Xiaoning Xu Jing Zhao Yucai Su School of Mathematics and Statistics Liaoning UniversityShenyang 110036China 不详

The natural filtrations of infinite-dimensional Lie superalgebras of O-type over a field of positive characteristic are proved to be invariant under automorphisms by studying ad-nilpotent *** observe that two Lie superalgebras of O-type are isomorphic if and only if the integers in the definition of these Lie superalgebras are ***,all the Lie superalgebras of O-type are classified in the sense of isomorphism.

关键词： filtration isomorphism classification

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Impact of Mo/Ni alloying on microstructural modulation and low-temperature toughness of high-strength low-alloy steel

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Journal of Iron and Steel Research International 2024年第7期31卷 1746-1762页

作者： Wei Liu Hong-li Zhao Bing-xing Wang Yong Tian State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819LiaoningChina

The high-strength low-alloy steel plates with varying Ni/Mo contents were manufactured using the thermos-mechanical control *** investigation was conducted to explore the effect of Ni/Mo microalloying on microstructure evolution and mechanical properties of the *** results revealed that the increase in Ni content from 1 to 2 wt.%reduced the transition temperature of ferrite and the growth range of ferritic grain was narrowed,which promoted grain *** optimized combination of grain size,high-angle grain boundaries(HAGBs),and martensite-austenite(M-A)islands parameter contributed to the excellent impact toughness of S1 steel at-100℃(impact absorbed energy of 218.2 J at-100℃).As the Mo increases from 0 to 2 wt.%,the matrix structure changes from multiphase structure to granular bainite,which increases the average effective grain size to~4.62 pm and reduces HAGBs proportion to~36.22%.With these changes,the low-temperature impact toughness of S3 steel is *** addition,based on the analysis of the characteristics of crack propagation path,it was found that M-A islands with low content(~2.21%)and small size(~1.76 pm)significantly retarded crack propagation,and the fracture model of M-A islands with different morphologies was further ***,correlation between behaviour of delamination and toughness was further analysed by observing delamination size and impact energy parameters.

关键词： High-strength low-alloy steel Microstructural regulation Ni addition Mo addition Crack propagation Low-temperature toughness

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Color Image Compression and Encryption Algorithm Based on 2D Compressed Sensing and Hyperchaotic System

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Computers, Materials & Continua 2024年第2期78卷 1977-1993页

作者： Zhiqing Dong Zhao Zhang Hongyan Zhou Xuebo Chen School of Computer Science and Software Engineering University of Science and Technology LiaoningAnshan114051China School of Electronic and Information Engineering University of Science and Technology LiaoningAnshan114051China

With the advent of the information security era,it is necessary to guarantee the privacy,accuracy,and dependable transfer of *** study presents a new approach to the encryption and compression of color *** is predicated on 2D compressed sensing(CS)and the hyperchaotic ***,an optimized Arnold scrambling algorithm is applied to the initial color images to ensure strong ***,the processed images are con-currently encrypted and compressed using 2D *** them,chaotic sequences replace traditional random measurement matrices to increase the system’s ***,the processed images are re-encrypted using a combination of permutation and diffusion *** addition,the 2D projected gradient with an embedding decryption(2DPG-ED)algorithm is used to reconstruct *** with the traditional reconstruction algorithm,the 2DPG-ED algorithm can improve security and reduce computational ***,it has better *** experimental outcome and the performance analysis indicate that this algorithm can withstand malicious attacks and prove the method is effective.

关键词： Image encryption image compression hyperchaotic system compressed sensing

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State of the art of lightweight aggregates used in lightweight refractories for working lining of high-temperature furnaces

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Journal of Iron and Steel Research International 2024年第6期31卷 1320-1343页

作者： Wei Zhang Wen-yong Dai Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina Research and Development Department AGC Plibrico(Dalian)Industries Inc.Dalian 116600LiaoningChina

Lightweight refractories for the working lining of high-temperature furnaces play an important role in the smelting of advanced steels and *** prepare lightweight refractories for the working lining of high-temperature furnaces,the synthesis of lightweight aggregates is the ***,the research on the synthesis of lightweight aggregates with high service temperature,low thermal conductivity,high strength,and good slag resistance has received widespread *** available literature on the synthesis of lightweight aggregates was summarized,including corundum,mullite,mullite-corundum,spinel,corundum-spinel,cordierite,cordierite-mullite,calcium hexaluminate,corundum-calcium hexaluminate,bauxite,magnesia,magnesia-based,and forsterite-based ***,the future development trend of lightweight aggregates was proposed.

关键词： Lightweight aggregate Lightweight refractory Working lining Apparent porosity Closed porosity Thermal conductivity Pore-forming approach

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Hydroxysafflor Yellow A Promotes HaCaT Cell Proliferation and Migration by Regulating HBEGF/EGFR and PI3K/AKT Pathways and Circ_0084443

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Chinese Journal of Integrative Medicine 2024年第3期30卷 213-221页

作者： ZHANG Yue XIAO Yan-wei MA Jing-xin WANG Ao-xue Department of Dermatology the Second Hospital of Dalian Medical UniversityDalianLiaoning Province116021China Department of Cell Biology Dalian Medical UniversityDalianLiaoning Province116044China

Objective:To investigate the effect and possible mechanism of hydroxysafflor yellow A(HSYA) on human immortalized keratinocyte cell proliferation and ***:HaCaT cells were treated with *** proliferation was detected by the cell counting kit-8 assay,and cell migration was measured using wound healing assay and Transwell migration *** mRNA and protein expression levels of heparin-binding epidermal growth factor(EGF)-like growth factor(HBEGF),EGF receptor(EGFR),phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),mammalian target of rapamycin(mTOR),and hypoxia-inducible factor-1α(HIF-1α) were detected by quantitative real-time polymerase chain reaction(qRT-PCR) and Western blot,***_0084443-overexpressing HaCaT cells and empty plasmid HaCaT cells were constructed using the lentiviral stable transfection and treated with *** expression of circ_0084443 was detected by ***:HSYA(800 μmol/L) significantly promoted HaCaT cell proliferation and migration(P0.05).Conclusion:HSYA played an accelerative role in HaCaT cell proliferation and migration,which may be attributable to activating HBEGF/EGFR and PI3K/AKT signaling pathways,and had a particular inhibitory effect on the keratinocyte negative

关键词： hydroxysafflor yellow A circ_0084443 heparin-binding epidermal growth factor-like growth factor/epidermal growth factor receptor phosphatidylinositol 3-kinase/protein kinase B

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Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates

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World Journal of Gastroenterology 2024年第2期30卷 184-195页

作者： Yan-Meng Wang Mo-Ye Chen Jing Chen Xin-He Zhang Yan Feng Yu-Xi Han Yi-Ling Li Department of Gastroenterology The First Affiliated Hospital of China Medical UniversityShenyang 110000Liaoning ProvinceChina Key Laboratory of Cancer Etiology and Prevention in liaoning Education Department The First Hospital of China Medical UniversityShenyang 110000Liaoning ProvinceChina

BACKGROUND Resistance to clarithromycin(CLA)and levofloxacin(LFX)of Helicobacter pylori(***)is increasing in severity,and successful eradication is ***,the eradication success rate has greatly declined,leaving a large number of patients with previous treatment *** To investigate secondary resistance rates,explore risk factors for antibiotic resistance,and assess the efficacy of susceptibility-guided *** We recruited 154 subjects positive for Urea Breath Test who attended The First Affiliated Hospital of China Medical University between July 2022 and April *** underwent a string test after an overnight *** gastric juice was obtained and transferred to vials containing storage ***,DNA extraction and the specific DNA amplification were performed using quantitative polymerase chain reaction(qPCR).Demographic information was also analyzed as part of the *** on these results,the participants were administered susceptibility-guided *** was compared with that of the empiric treatment *** A total of 132 individuals tested positive for the *** ureA gene by qPCR *** resistance rate reached a high level of 82.6%(n=109),LFX resistance rate was 69.7%(n=92)and dual resistance was 62.1%(n=82).Gastric symptoms[odds ratio(OR)=2.782;95%confidence interval(95%CI):1.076-7.194;P=0.035]and rural residence(OR=5.152;95%CI:1.407-18.861;P=0.013)were independent risk factors for secondary resistance to CLA and LFX,respectively.A total of 102 and 100 individuals received susceptibility-guided therapies and empiric treatment,*** antibiotic susceptibility-guided treatment and empiric treatment groups achieved successful eradication rates of 75.5%(77/102)and 59.0%(59/411)by the intention-to-treat(ITT)analysis and 90.6%(77/85)and 70.2%(59/84)by the per-protocol(PP)analysis,*** eradication rates of these two treatment strategies were significantly

关键词： Helicobacter pylori Antibiotic resistance Clarithromycin Levofloxacin String-test Susceptibility-guided therapy Eradication rate

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