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Physics-based seismic analysis of ancient wood structure:fault-to-structure simulation

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 727-740页

作者： Ba Zhenning Fu Jisai Wang Fangbo Liang Jianwen Zhang Bin Zhang Long State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation (Tianjin University)Tianjin 300350China School of Civil Engineering Tianjin UniversityTianjin 300350China Administrative Office of the Summer palace Beijing 100091China School of Architecture Tianjin UniversityTianjin 300072China

Based on the domain reduction method,this study employs an SEM-FEM hybrid workflow which integrates the advantages of the spectral element method(SEM)for flexible and highly efficient simulation of seismic wave propagation in a three-dimensional(3D)regional-scale geophysics model and the finite element method(FEM)for fine simulation of structural response including soil-structure interaction,and performs a physics-based simulation from initial fault rupture on an ancient wood *** verification of the hybrid workflow,a large-scale model of an ancient wood structure in the Beijing area,The Tower of Buddhist Incense,is established and its responses under the 1665 Tongxian earthquake and the 1730 Yiheyuan earthquake are *** results from the simulated ground motion and seismic response of the wood structure under the two earthquakes demonstrate that this hybrid workflow can be employed to efficiently provide insight into the relationships between geophysical parameters and the structural response,and is of great significance toward accurate input for seismic simulation of structures under specific site and fault conditions.

关键词： spectral element method finite element method fault-to-structure simulation physical model domain reduction method

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非物质文化遗产的标准化研究

China Standardization 2024年第4期128卷 60-63页

作者：韩知佑 The palace Museum

Intangible cultural heritage is an important part of human civilization,and its protection and inheritance are of great significance for maintaining the diversity of national culture and the continuity of traditional *** order to better protect intangible cultural heritage,many countries have formulated corresponding protection standards and *** paper summarizes and studies the current standardization development of intangible cultural heritage protection in various countries,explores its significance,current situation,and development trends,and provides suggestions for the standardization of intangible cultural heritage protection in China.

关键词： intangible cultural heritage standardization inheritance diversity

Characterization and evaluation of UV-irradiation aging of urushi by micro-UV/Py-GC/MS system

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Science China(Technological Sciences) 2023年第8期66卷 2258-2270页

作者： WANG Na GU An LEI Yong Department of Conservation Science The Palace MuseumBeijing 100009China

Lacquer is the main raw material of lacquerware,while UV-irradiation is an important factor leading to its *** order to investigate the aging behavior of urushi lacquer film under UV-irradiation,and to propose parameters that can be used to evaluate its aging degree,the micro-UV/Py-GC/MS system has been applied in the present work to enrich and identify volatile products released by urushi film during aging on the one hand,and to investigate micro-amount and conventional urushi films with different aging degrees on the other hand,in addition,representative historical samples have also been *** products released by urushi film demonstrate that during UV-irradiation,polysaccharides wrapping urushiol polymer would be first degraded to generate furans and alcohols,and then urushiol polymer would undergo photo-oxidation and break of molecular chain,mainly generating oxidation products including aldehydes,organic acids,and ketones,as well as a small number of alkyl benzenes and ***-GC/MS analysis of micro-amount urushi films with different aging degrees indicates that UVirradiation is more destructive to aliphatic chains in urushiol polymer,but it also can accelerate the polymerization of microamount urushi ***-GC/MS analysis of conventional urushi films indicates that with the increase of aging degree,the total chromatographic peak area ratio of hydrocarbons to benzene derivatives gradually increases,the peak area ratio of 3-pentadecenyl-catechol to 3-pentadecyl-catechol gradually decreases,and the peak area ratio of aging products of urushiol to 3-pentadecyl-catechol gradually *** above parameters were further used to evaluate the aging degree of two urushicontained samples separately collected from the surface and interior of a carved lacquer panel in the Forbidden City,and evaluation results are in accord with the natural aging law and further verify the reliability of the proposed *** results of the pre

关键词： urushi UV-irradiation aging micro-UV/Py-GC/MS aging degree evaluation

Correlation analysis of liver tumor-associated genes with liver regeneration

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World Journal of Gastroenterology 2007年第24期13卷 3323-3332页

作者： Cun-Shuan Xu Shou-Bing Zhang Xiao-Guang Chen Salman Rahman College of Life Science Henan Normal University Xinxiang 453007 Henan Province China Key Laboratory for Cell Differentiation Regulation Xinxiang 453007 Henan Province China Laboratory of Thrombosis and Vascular Remodelling Division of Cardiovascular Medicine King's College London School of Medicine St Thomas' Hospital Lambeth Palace Road London SE1 7EH United Kingdom

AIM: To study at transcriptional level the similarities and differences of the physiological and biochemical activities between liver tumor (LT) and regenerating liver cells. METHODS: LT-associated genes and their expression changes in LT were obtained from databases and scientific articles, and their expression profiles in rat liver regeneration (LR) were detected using Rat Genome 230 2.0 array. Subsequently their expression changes in LT and LR were compared and analyzed. RESULTS: One hundred and twenty one LT-associated genes were found to be LR-associated. Thirty four genes were up-regulated, and 14 genes were down-regulated in both LT and regenerating liver; 20 genes up-regulated in LT were down-regulated in regenerating liver; 21 up-regulated genes and 16 down-regulated genes in LT were up-regulated at some time points and down-regulated at others during LR. CONCLUSION: Results suggested that apoptosis activity suppressed in LT was still active in regenerating liver, and there are lots of similarities and differences between the LT and regenerating liver at the aspects of cell growth, proliferation, differentiation, migration and angiogenesis.

关键词： Partial hepatectomy Rat Genome 230 2.0Array Apoptosis Liver regeneration-associated gene Liver tumor-associated gene

Clinico-pathological aspects of colorectal serrated adenomas

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World Journal of Gastroenterology 2006年第17期12卷 2770-2772页

作者： Ashish Chandra Adnan A Sheikh Anton Cerar Ian C Talbot Department of Pathology St Thomas' Hospital Lambeth Palace RoadLondonSE1 7EHUnited Kingdom Department of Surgery Royal Liverpool University Hospital Prescot RoadLiverpoolL7 8XPUnited Kingdom Institute of Pathology Medical Faculty Korytkova 21105 LjubljanaSlovenia Academic Department of Pathology St Mark's and Northwick Park Hospitals NHS Trust HarrowMiddlesexHA1 3UJUnited Kingdom

AIM： To study the association of colorectal serrated adenomas （SAs） with invasive carcinoma, local recurrence, synchronicity and metachronicity of lesions. METHODS： A total of 4536 polyps from 1096 patients over an eight-year period （1987-1995） were retrospectively examined. Adenomas showing at least 50% of serrated architecture were called SAs by three reviewing pathologists. RESULTS： Ninety-one （2%） of all polyps were called SAs, which were found in 46 patients. Invasive carcinomas were seen in 3 out of 46 （6.4%） patients, of whom one was a case of familial adenomatous polyposis （FAP）. A male preponderance was noted and features of a mild degree of dysplasia were seen in majority （n=75, 83%） of serrated adenomas. Follow-up ranged 1-12 years with a mean time of 5.75 years. Recurrences of SAs were seen in 3 （6.4%） cases, synchronous SAs in 16 （34.8%） cases and metachronous SAs in 9 （19.6%） cases. CONCLUSION： Invasive carcinoma arising in serrated adenoma is rare, accounting for 2 （4.3%） cases studied in this series.

关键词： Serrated adenoma Carcinoma Polyps Colorectum

Paving the Way to Open Data

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Data Intelligence 2019年第4期1卷 368-380页

作者： Yan Wu Elizabeth Moylan Hope Inman Chris Graf Wiley 805-808 Sun PalaceNo.12A Taiyanggong Middle RoadBeijing 100028China Wiley 9600 Garsington RoadOxfordOX42DQUK Wiley 111 River StreetHobokenNJ 07030USA

It is easy to argue that open data are critical to enabling faster and more effective research *** this article,we describe the approach we have taken at Wiley to support open data and to start enabling more data to be FAIR data(Findable,Accessible,Interoperable and Reusable)with the implementation of four data policies:“Encourages”,“Expects”,“Mandates”and“Mandates and Peer Reviews Data”.We describe the rationale for these policies and levels of adoption so *** the coming months we plan to measure and monitor the implementation of these policies via the publication of data availability statements and data *** this information,we’ll be able to celebrate adoption of data-sharing practices by the research communities we work with and serve,and we hope to showcase researchers from those communities leading in open research.

关键词： Open data Data sharing Data citation Open research

Association of metabolic syndrome with arterial compliance in children and adolescents

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Frontiers of Medicine 2007年第1期1卷 68-73页

作者： ZHANG Li MI Jie LI Ming JIANG Benyu Department of Epidemiology Capital Institute of PediatricsBeijing 100020China Department of Endocrinology Chinese Academy of Medical SciencePeking Union Medical College HospitalBeijing 100730China Clinical Pharmacology St Thomas’HospitalLambeth Palace RdLondon SEI 7EHUK

The association of metabolic syndrome(MS)with arterial compliance in children and adolescents was explored.337 subjects(188 men and 149 women)aged 6–18(10.95±3.01)years,out of“Beijing Child Metabolic Syndrome Study”,were divided into three case groups(one component,two components,three&more components of MS)and one control group based on the Cook’s MS definition in children and *** including anthropometry,blood pressure,fasting plasma glucose and insulin,serum lipid profile were *** model assessment for insulin resistance(HOMA-IR)index was calculated for estimating individual insulin *** compliance was measured using digital pulse wave analyzing method from the pulse trace machine(Micro medical,London),and then the stiffness index(SI)was *** mean value of SI in MS group was significant higher than that in control group[(7.69±1.63)vs(6.25±0.86)m/s,P<0.01].With the increase of the clustering of MS components,SI and HOMA-IR were gradually *** taking account of gender,age and pubertal development,the partial correlation analysis showed that the amount of components of MS and HOMA-IR were positively correlated with SI(both P values were less than 0.05).The arterial compliance of MS group was significantly lowered in children and adolescents,and with the increase of the clustering of MS components,arterial compliance was gradually *** was suggested that arterial compliance assessment in children and adolescents was important for early prevention of cardiovascular diseases.

关键词： metabolic syndrome arterial compliance children and adolescents

Techniques of Wallpaper(Biao Hu)in the palace Museum:A Case Study of the Lodge of Bamboo Fragrance(Zhuxiang Guan)

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Paper And Biomaterials 2023年第3期8卷 29-37页

作者： Yue Ma Department of Conservation Science and Technology The Palace MuseumBeijing100009China Key Laboratory of Calligraphy and Paintings Conservation Ministry of Culture and TourismBeijing100020China

Biao Hu was one of the eight famous traditional crafts in the late Qing *** skill involved decorating the interiors of ancient buildings such as ceilings,walls,and windows and creating burial *** was primarily used for wooden buildings in northern China during the early Qing *** example,there is white-patterned wallpaper in the Forbidden City utilizing both traditional and nontraditional ***,there was wallpaper with a special pattern in the Lodge of the Bamboo Fragrance(Zhuxiang Guan).Its structure and composition were studied via morphological observations and spectral analyses,the pigments and dyes were analyzed by Raman spectroscopy and ultra-high performance liquid chromatography-mass spectrum(UPLC-MS).Traditional technology and exchanges between China and the West were discussed by the study of patterned wallpapers in other buildings of the Forbidden City.

关键词： the palace Museum wallpaper wooden structure

口服抗氧化剂raxofelast可降低男性Ⅱ型糖尿病患者的氧化应激及改善内皮功能

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Oncology and Translational Medicine 2001年第6期18卷 17-18页

作者： P.J.Chowienczyk,S.E.Brett,N.K.Gopaul,D.Meeking,M.Marchetti,D.L.Russell-Jones,E.E.(?)ngg(?)rd,J.M.Ritter,袁刚 Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road Department of Clinical Pharmacology St Thomas’Hospital lambeth palace road 华中科技大学同济医学院附属同济医院 London SE1 7EH UK London SE1 7EH UK London SE1 7EH UK London SE1 7EH UK London SE1 7EH UK London SE1 7EH UK London SE1 7EH UK London SE1 7EH UK

Ⅱ型糖尿病以氧化应激增加和内皮功能紊乱为特征。二者在动脉粥样硬化性疾病发生和发展中起重要作用。短期动脉注射维生素C能增加Ⅱ型糖尿病患者内皮依赖的血管舒张反应,提示内皮功能障碍继发于氧化应激增加,可能原因为活性氧族如过氧... 详细信息

Ⅱ型糖尿病以氧化应激增加和内皮功能紊乱为特征。二者在动脉粥样硬化性疾病发生和发展中起重要作用。短期动脉注射维生素C能增加Ⅱ型糖尿病患者内皮依赖的血管舒张反应,提示内皮功能障碍继发于氧化应激增加,可能原因为活性氧族如过氧化物阴离子阻断内皮来源的NO。为了解口服抗氧化剂能否降低Ⅱ型糖尿病患者氧化应激及改善内皮功能,我们研究一种新的类维生素E的水溶性抗氧化剂raxofelast在糖尿病及正常人中的作用。检测血浆8-epi-PGF2α浓度表示氧化应激,输注乙酰胆碱后血管的反应性表示内皮功能。

关键词： Ⅱ型糖尿病二型糖尿病氧化应激内皮功能患者抗氧化剂