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检索条件"机构=Laboratory of Genetic Toxicology"
183 条 记 录,以下是1-10 订阅
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Behind the curtain of non-coding RNAs; long non-coding RNAs regulating hepatocarcinogenesis
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World Journal of Gastroenterology 2018年 第5期24卷 549-572页
作者: Aya El Khodiry Menna Afify Hend M El Tayebi genetic Pharmacology Research Group Clinical Pharmacy Unit department of Pharmacology and toxicology faculty of Pharmacy and biotechnology German University in Cairo
Hepatocellular carcinoma(HCC) is one of the most common and aggressive cancers worldwide. HCC is the fifth common malignancy in the world and the second leading cause of cancer death in Asia. Long non-coding RNAs(lncR... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
genetic polymorphisms in HIFIA are associated with prostate cancer risk in a Chinese population
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Asian Journal of Andrology 2012年 第6期14卷 864-869页
作者: Pu Li Qiang Cao Peng-Fei Shao Hong-Zhou Cai Hai Zhou Jia-Wei Chen Chao Qin Zheng-Dong Zhang Xiao-Bing Ju Chang-Jun Yin State Key laboratory of Reproductive Medicine Department of Urology The First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China Department of Molecular and genetic toxicology School of Public Health Nanjing Medical University Nanjing 210029 China
The hypoxia-inducible factor-1α(HIF-1α) plays an important role in regulating angiogenesis, which is essential for tumor growth and metastasis. genetic variations of HIFIA (coding HIF-1α) have been shown to inf... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Chemopreventive Effects of Black Tea Polyphenols in Mouse Skin Model of Carcinogenesis
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Biomedical and Environmental Sciences 1998年 第4期11卷 307-313页
作者: SEEMA JAVED N. K. MEHROTRA AND YOGESHWER SHUKLA(laboratory of Environmental Chrcinogenesis, Industrial toxicology Research Centre, M. G. Marg, P. O. Box 80,Lucknow - 226001, India) laboratory of Environmental Carcinogenesis Industrial Toxicology Research Centre Lucknow India.
In the present investigations, the antitumorigenic effect of black tea polyphenols (BTP) in twcrstage mouse skin model of carcinogenesis was studied. The animals were initiated with a single 'subcarcinogenic' topical ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients
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World Journal of Gastroenterology 2017年 第21期23卷 3864-3875页
作者: Moustafa Nouh Elemeery Ahmed Noah Badr Marwa Anwar Mohamed Doaa Ahmed Ghareeb Medical Biotechnology laboratory Genetic Engineering and Biotechnology Research DivisionNational Research Centre toxicology and Food Contaminant laboratory Food Science and Nutrition Research DivisionNational Research Centre Department of Chemical Pathology Medical Research InstituteAlexandria University Molecular Biology laboratory Faculty of ScienceAlexandria University
AIM To investigate the prospective importance of serum micro(mi)RNAs(mi R-125 b, mi R-138 b, mi R-1269, mi R-214-5p, mi R-494, mi R375 and mi R-145) as early biomarkers for the diagnosis of hepatitis C virus(HCV)-rela... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Active regions' setting of the extracellular ligand-binding domain of human interleukin-6 receptor
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Chinese Science Bulletin 2000年 第13期45卷 1182-1187页
作者: Yunfang Ren Hong Qu Jiannan Feng Song Li Beifen Shen Institute of Basic Medical Sciences Academy of Military Medical Sciences Beijing China National laboratory of Protein Engineering and Plant genetic Engineering Peking University Beijing China Institute of Pharmacology and toxicology Academy of Military Medical Sciences Beijing China
The reliable three dimensional (3-D) structure of the extracellular ligand-binding domain (V106-P322) of human interleukin-6 receptor (hlL-6R) has been constructed by means of computer-guided homology modeling techniq... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Biological functions and potential implications of circular RNAs
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The Journal of Biomedical Research 2023年 第2期37卷 89-99页
作者: Lan Ma Haiyan Chu Meilin Wang Zhengdong Zhang Department of genetic toxicology The Key Laboratory of Modern Toxicology of Ministry of EducationCenter for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China Department of Environmental Genomics Jiangsu Key Laboratory of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineNanjing Medical UniversityNanjingJiangsu 211166China.
Circular RNAs(circRNAs) are characterized by a covalent closed-loop structure with an absence of both 5′ cap structure and 3′ polyadenylated tail. Numerous studies have found that circRNAs play an important role in ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Efficacy evaluation and neurobiological mechanism of psychedelics based on looming model
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中国药理学与毒理学杂志 2023年 第7期37卷 533-534页
作者: XIA Ke YAN Haitao SU Ruibin Beijing Key laboratory of Neuropsychopharmacology State Key Laboratory of Toxicology and Medical Countermeasures Institute of Pharmacology and Toxicology Academy of Military Medical Sciences
OBJECTIVE To investigate the effect of psychedelics on innate fear behavior of mice in Looming model(LM) and its neurobiological mechanism. METHODS(1) Adult male C57BL/6J mice were randomly divided into saline group, ...
来源: 同方期刊数据库 同方期刊数据库 评论
Potential Adverse Outcome Pathways of Chlorinated Organophosphate Flame Retardants
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China CDC weekly 2024年 第23期6卷 542-546,I0008-I0011页
作者: Meiyu Zhou Huilin Zhang Qi Xiao Kexin Li Xiaoting Li Haiyan Chu Department of Environmental Genomics Jiangsu Key Laboratory of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineSchool of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of genetic toxicology The Key Laboratory of Modern Toxicology of Ministry of EducationCenter of Global HealthSchool of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of Nutrition and Food Safety School of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina
What is already known about this topic?Chlorinated organophosphate flame retardants(Cl-OPFRs)are frequently detected chemicals in the environment and biological samples,yet there is a lack of systematic evaluation reg... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
genetic variants in C1GALT1 are associated with gastric cancer risk by influencing immune infiltration
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Journal of Biomedical Research 2024年 第4期38卷 348-357页
作者: Mengfan Guo Jingyuan Liu Yujuan Zhang Jingjing Gu Junyi Xin Mulong Du Haiyan Chu Meilin Wang Hanting Liu Zhengdong Zhang Departments of Environmental Genomics and genetic toxicology the Key Laboratory of Modern Toxicology of Ministry of EducationCenter for Global HealthJiangsu Key Laboratory of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineSchool of Public Health/Institute of Clinical Researchthe Affiliated Taizhou People's Hospital of Nanjing Medical UniversityNanjing Medical UniversityNanjingJiangsu 211166China Departments of Environmental Genomics and genetic toxicology the Key Laboratory of Modern Toxicology of Ministry of EducationCenter for Global HealthJiangsu Key Laboratory of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineSchool of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China Department of Bioinformatics School of Biomedical Engineering and InformaticsNanjing Medical UniversityNanjingJiangsu 211166China Department of Biostatistics Center for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China
Core 1 synthase glycoprotein-N-acetylgalactosamine 3-β-galactosyltransferase 1(C1GALT1)is known to play a critical role in the development of gastric cancer,but few studies have elucidated associations between geneti... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Aristolochic Acid-Induced Genotoxicity and Toxicogenomic Changes in Rodents
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World Journal of Traditional Chinese Medicine 2020年 第1期6卷 12-25页
作者: Xi-Lin Li Xiao-Qing Guo Hai-Rong Wang Tao Chen Nan Mei Division of genetic and Molecular toxicology National Center for Toxicological ResearchJeffersonARUSA Tianjin Center for New Drug Safety Assessment and Research TianjinChina
Aristolochic acid(AA)is a group of structurally related nitrophenanthrene carboxylic acids found in many plants that are widely used by many cultures as traditional herbal *** is a causative agent for Chinese herbs ne... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论