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Journal of Geographical Sciences 2023年第12期33卷 2511-2529页

作者：陈巧湄岳伟鹏陈峰马丁·哈达德菲德尔·罗伊格赵晓恩胡茂曹红华 Yunnan Key laboratory of International Rivers and Transboundary Eco-Security Institute of International Rivers and Eco-SecurityYunnan UniversityKunming650500China Key laboratory of Tree-ring Physical and Chemical Research of the Chinese Meteorological Administration/Xinjiang laboratory of Tree-ring Ecology Institute of Desert MeteorologyChinese Meteorological AdministrationUrumqi830002China laboratorio de dendrocronología de ZonasÁridas CIGEOBIO(COnICET-UnSJ) Gabinete de Geología Ambiental(INGEO-UNSJ)San JuanArgentina laboratorio de dendrocronología e Historia Ambiental IANIGLA-CCT CONICET-Universidad Nacional de CuyoMendozaArgentina Hémera Centro de Observación de la Tierra Escuela de Ingeniería ForestalFacultad de CienciasUniversidad MayorHuechurabaSantiagoChile

In the past 30 years,observational climate datasets reveal a significant a drying and warming trend over in north *** of climatic variability over north China and its driving mechanism in a long-term perspective is,however,limited to a few sites only,especially the lack of temperature reconstructions based on latewood density and blue *** this study,we developed a 281-year latewood blue intensity chronology based on 45 cores of Picea meyeri in western north *** on the discovery that the warm season(May–August)mean maximum temperature is the main controlling factor affecting the change in blue light reflection intensity,we established a regression model that explained 37%of the variance during the calibration period(1950–2020),allowing to trace the mean maximum temperature up to 1760 *** the past 261 years,we identified seven persistent high temperature periods(1760–1773,1778–1796,1805–1814,1869–1880,1889–1934,1984–2000,2004–2020)and three persistent low temperature periods(1815–1868,1935–1963,1969–1983)in north *** of a nearby temperature reconstructions and climate gridded data indicate that our reconstruction record a wide range of temperature variations in north *** analysis of links between large-scale climatic variation and the temperature reconstruction showed that there is a relationship between extremes in the warm season temperature and anomalous SSTs in the equatorial eastern Pacific,and implied that the extremes in the warm season temperature in north China will be intensified under future global warming.

关键词： blue intensity Picea meyeri mean maximum temperature north China dendroclimatology

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In the era of rapid mRnA-based vaccines:Why is there no effective hepatitis C virus vaccine yet?

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World Journal of Hepatology 2021年第10期13卷 1234-1268页

作者： natalia Echeverria Victoria Comas Fabian Aldunate Paula Perbolianachis Pilar Moreno Juan Cristina laboratorio de Virologia Molecular Centro de Investigaciones NuclearesFacultad de CienciasUniversidad de la RepublicaMontevideo 11400Uruguay laboratorio de Evolucion Experimental de Virus Institut PasteurMontevideo 11400Uruguay departamento de desarrollo Biotecnologico Instituto de HigieneFacultad de MedicinaUniversidad de la RepublicaMontevideo 11600Uruguay

Hepatitis C virus(HCV)is responsible for no less than 71 million people chronically infected and is one of the most frequent indications for liver transplanta-tion *** direct-acting antiviral therapies fuel optimism in controlling HCV infections,there are several obstacles regarding treatment accessibility and reinfection continues to remain a ***,the majority of new HCV infections in developed countries occur in people who inject drugs and are more plausible to get *** achieve global epidemic control of this virus the development of an effective prophylactic or therapeutic vaccine becomes a *** coronavirus disease 19(COVID-19)pandemic led to auspicious vaccine development against severe acute respiratory syndrome coronavirus-2(SARSCoV-2)virus,which has renewed interest on fighting HCV epidemic with *** aim of this review is to highlight the current situation of HCV vaccine candidates designed to prevent and/or to reduce HCV infectious cases and their *** will emphasize on some of the crossroads encountered during vaccine development against this insidious virus,together with some key aspects of HCV immunology which have,so far,ham-pered the progress in this *** main focus will be on nucleic acid-based as well as recombinant viral vector-based vaccine candidates as the most novel vaccine approaches,some of which have been recently and successfully employed for SARS-CoV-2 ***,some ideas will be presented on which methods to explore for the design of live-attenuated vaccines against HCV.

关键词： Hepatitis C virus Vaccine candidates nucleic acid-based vaccines Recombinant vector-based vaccines Challenges COVID-19

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laboratory Handling of Didymosphenia geminata (Lyngbye) Schmidt and the Effect of Control Efforts on Viability

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Advances in Bioscience and Biotechnology 2015年第8期6卷 508-516页

作者： Jorge Parodi Pamela Olivares Viviana Chavez Matías Peredo-Parada laboratorio fisiología de la reproducción Escuela de Medicina Veterinaria Núcleo de Investigaciónen Producción Alimentaria Facultad de Recursos Naturales Universidad Católica de Temuco Temuco Chile laboratorio de Investigación y Educación Tonalli Ltda Temuco Chile departamento de Ingenieríaen Obras Civiles Universidad de Santiago de Chile Santiago Chile Plataforma de Investigaciónen Ecohidrología y Ecohidráulica EcoHyd Ltda Santiago Chile

Didymosphenia geminata (Lyngbye) Schmidt is a type of diatom that exists in Chile as an introduced species, invading the country and its rivers. We collected samples of D. geminata from two sampling points in Chile, assessing their viability and response to control agents. Fresh D. geminata showed more than 90% of viable granular forms (containing granules in their cytoplasm);however, the dry form presents near 50% viability. By creating dry D. geminata through exposure to 38°C temperatures for 7 days, viability values of the granular form decreased to 20%. D. geminata kept at room temperature for more than 4 weeks reported values of granular forms at 50%, while samples that were refrigerated at 4°C maintained values of granular forms at 90% for 4 weeks. Previous studies suggest that high salt concentration affects the viability of D. geminata. When taking wet D. geminata samples and exposing them to a solution of 10% naCl for 10 minutes, we observed no differences compared to the control samples, finding granular forms at 90%. When the D. geminata was exposed to a 5% soap solution, reductions of over 90% of the granular forms were observed. Our results suggest that the viability of D. geminata is associated with the granular content within their cytoplasm, and that it is possible to alter laboratory conditions for their study. These early studies are important in order to better manipulate the model in the laboratory, allowing us to obtain new evidence regarding the microalgae’s biology through in vitro studies.

关键词： Plague Viability laboratory Didymo

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The largest dengue outbreak in Argentina and spatial analyses of dengue cases in relation to a control program in a district with sylvan and urban environments

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Asian Pacific Journal of Tropical Medicine 2018年第3期11卷 227-234页

作者： Aníbal E Carbajo Alejandra Rubio María J Viani María R Colombo laboratorio de Eoclogía de Enfermedades Transmitidas por Vectores Instituto de Investigación e Ingeniería AmbientalUniversidad Nacional de General San Martín Consejo nacional de Investigaciones Científicas y Técnicas Secretaria de Política Sanitaria y desarrollo Humano Municipio de Tigre

Objective: To analyze the largest outbreak of dengue in Argentina in the municipality of Tigre during 2016, through detailed spatial analyses of the occurrence of cases in relation to demographic factors and vector control actions. Methods: detailed and georreferenced data on dengue cases with laboratory results(nS1 or IgM) were analyzed. The occurrences of imported and autochthonous cases by census tract were modeled using demographic variables(population by age class, proportion of foreigners, proportion with university grade, proportion of males), dwelling variables(number of homes, proportion of dwellings with latrine, number of dwellings, proportion of houses, proportion of flats, proportion of slums) and census tract area as explanatory variables. The probability of occurrence of autochthonous and imported cases was modeled separately. The spatio-temporal occurrence of cases was studied in relation to focal and perifocal control actions(involving education campaigns, removal of Aedes aegypti breeding sites and exhaustive insecticide spraying) to assess the efficiency in stopping autochthonous cases spreading. Results: All autochthonous cases occurred in the urban environment with no sylvan cases. The majority of the imported cases registered came from Paraguay and northeastern Argentina. The age structure of imported and autochthonous cases did not differ from the age structure of the municipality, while that of the negative cases *** studied spatially, the occurrence of imported cases by census tract was mildly associated with a higher proportion of foreign population and more people at active age, while occurrence of autochthonous cases was not significantly associated with any of the studied *** census tracts with laboratory confirmed results, the models showed higher probability of autochthonous cases related to higher population density and population age structure. The clustering of autochthonous cases was generally mild, with prevailing i

关键词： Aedes aegypti Vector-borne diseases Vector control dengue epidemic

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Influence of ZnO nanoparticles on the microstructure of a CoCrFeMoni matrix via powder metallurgy

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International Journal of Minerals,Metallurgy and Materials 2019年第11期26卷 1467-1476页

作者： C.D.Gómez-Esparza A.Duarte-Moller C.López-Díaz de León R.Martínez-Sánchez J.F.Hernández-Paz C.A.Rodríguez-González centro de investigación en materiales avanzados(cimav) laboratorio nacional de nanotecnologíamiguel de cervantes no.120chihuahua 31136chi8.mexico facultad de ingeniería civil mecánica e industrialuniversidad de la salle bajíoav.universidad 602león 37150gto.mexico instituto de ingeniería y tecnología universidad autónoma de ciudad juárez(uacj)av.del charro 450 nortec4.juárez 32310chi8.mexico

In the last decade,extensive research has been carried out on the microstructural behavior of high-entropy alloys(HEA),for which the in-situ formation of nanoparticles has been ***,studies of the incorporation of nanoparticles in HEA have been rarely *** this work,the addition of zinc oxide nanoparticles(ZnO nP)as reinforcement in a CoCrFeMoni high-entropy alloy matrix,as well as the morphological,structural,and microstructural evolution of composites synthesized via powder metallurgy,were *** electron microscopy and X-ray diffraction analysis were performed in order to study the microstructural and phase characterization of the *** sintering,it was found that the ZnO nP addition(0.5 wt%,1 wt%and 2 wt%)had a significant influence on the microstructure and hardness of the CoCrFeMoni high-entropy *** bonding among metal particles was promoted with the additions of Zn O nP.A reduction in porosity as a function of ZnO nP content was also *** microhardness results showed that the composite reached its highest reinforcement in bulk samples with 1 wt%ZnO nP(HV 870),which represented a 20%improvement over the unreinforced HEA matrix.

关键词： high-entropy alloy mechanical alloying nanoparticles composites

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Phylogeny,genetics,and the partial life cycle of Oncomegas wageneri in the Gulf of Mexico

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Current Zoology 2020年第3期66卷 275-283页

作者： Andrés MARTInEZ-AQUInO Víctor M.VIDAL-MARTInEZ F.Sara CECCARELLI Oscar MEndeZ Lilia C.SOLER-JIMEnEZ M.Leopoldina AGUIRRE-MACEDO Facultad de Ciencias Universidad Autonoma de Baja CaliforniaCarretera Transpeninsular 3917Fraccionamiento PlayitasEnsenadaBaja California 22860Mexico laboratorio de Patologia Acuatica Departamento de Recursos del MarCentro de Investigacion y de Estudios Avanzados del Instituto Politecnico NacionalUnidad MeridaCordemexCarretera Antigua a Progreso Km.6MeridaYucatan 97310Mexico departamento de Biologia de la Conservacion CONACYT-Centro de Investigacion Cientifica y de Educacion Superior de EnsenadaCarretera Ensenada-TjuanaEnsenadaBaja California 22860Mexico laboratorio de Hidrobiologia Facultad de Biologia-XalapaUniversidad VeracruzanaCircuito Gonzalo Aguirre Beltran S/N Zona UniversitariaXalapaVeracruz 91090Mexico

despite the diversity and ecological importance of cestodes,there is a paucity of studies on their life stages(i.e.,complete lists of intermediate,paratenic,and definitive hosts)and genetic *** example,in the Gulf of Mexico(GoM)98 species of cestodes have been reported to date;however,data on their intraspecific genetic variation and population genetic studies are *** trypanorhynch cestode,Oncomegas wageneri,is found(among other places)off the American Western Atlantic Coast,including the GoM,and has been reported as an adult from stingrays and from several teleost species in its larval form(as plerocerci).This study represents the first report of 2 previously unregistered definitive hosts for ***,namely the Atlantic sharpnose shark Rhizoprionodon terraenovae and the southern stingray Hypanus *** this work,partial sequences of the 28S(region D1-D2)ribosomal DnA were analyzed to include *** within an eutetrarhynchoid phylogenetic *** *** individuals(which included plerocerci and adults)were recovered as monophyletic and Oncomegas celatus was identified as the sister species of ***,population genetic analyses of *** from the southern GoM were carried out using DnA sequences of the mitochondrial cytochrome c oxi-dase subunit 1(COI)gene,which reflected high genetic variation and a lack of genetic structure among the 9 oceanographic sampling *** on these results,*** is panmictic in the southern *** extensive sampling along the species entire distribution is necessary to make more accurate inferences of population genetics of ***.

关键词： barcode Cyclopsetta chittendeni population genetics Hypanus americanus Oncomegas Rhizoprionodon terraeno-vae 28S rDnA(D1-D2)

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Application of high silica zeolite ZSM-5 in a hybrid treatment process based on sequential adsorption and ozonation for VOCs elimination

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Journal of Environmental Sciences 2016年第3期28卷 59-68页

作者： Hicham Zaitan Marie Hélène Manero Héctor Valdés laboratoire de Chirmie de la Matiere Condensee(LCMC) Faculte des Sciences et TechniquesUniversite Sidi Mohamed Ben AbdellahB.P.2202FesMaroc Universite de Toulouse INPTUPSLaboratoire de Genie Chimique4Allee Emile MonsoF-31030 ToulouseFrance CnRS Laboratoire de Genie ChimiqueF-31030 ToulouseFrance laboratorio de Tecnologias Limpias(F.Ingenieria) Universidad Catolica de la Santisima ConcepcionAlonso de Ribera 2850ConcepcionChile

In this study,a hydrophobic synthetic zeolite,namely ZSM-5 is chosen as an adsorbent/catalyst for toluene *** results showed that toluene adsorption onto ZSM-5 was favourable,following a langmuir adsorption isotherm ***-5 zeolite was regenerated using gaseous ozone at low *** toluene was oxidised,releasing mainly CO_2 and H_*** of oxidation by-products such as acetic acid and acetaldehyde were formed and remained adsorbed after the oxidativate regeneration with *** four successive cycles of adsorption/ozonation,the adsorption efficiency was not affected（92%-99%）.These results showed that volatile organic compound（VOC）removal by adsorption onto ZSM-5 zeolite followed by ozone regeneration could be used as a promising hybrid process for the control of VOC emissions in terms of efficiency.

关键词： Adsorption Ozone Toluene VOCs Zeolite

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Phase equilibrium modelling of the amphibolite facies metamorphism in the Yelapa-Chimo Metamorphic Complex, Mexico

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Geoscience Frontiers 2021年第1期12卷 293-312页

作者： Fabian Gutierrez-Aguilar Peter Schaaf Gabriela Solís-Pichardo Gerardo F.Arrieta-García Teodoro Hernandez-Trevino Carlos Linares-Lopez Posgrado en Ciencias de la Tierra Instituto de GeofísicaUniversidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico laboratorio Universitario de Geoquímica Isotopica(LUGIS) Instituto de GeofísicaUniversidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico laboratorio Universitario de Geoquímica Isotopica(LUGIS) Instituto de GeologíaUniversidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico Instituto de Geofísica Universidad Nacional Autonoma de MexicoAv.Universidad 3000Ciudad de Mexico04510Mexico

The Yelapa-Chimo Metamorphic Complex forms part of the Jalisco Block in western Mexico and exposes a wide range of Early Cretaceous metamorphic rocks;such as paragneiss,orthogneiss,amphibolites,and ***,the pressure-temperature(P-T)conditions of metamorphism and partial melting remain poorly studied in the *** elucidate metamorphic P-T conditions,phase equilibrium modelling was applied to two sillimanite-garnet paragneisses,one amphibole-orthogneiss,and one ***-garnet paragneisses exhibit a lepidoblastic texture with a biotite+sillimanite+kyanite+garnet+quartz+plagioclase+K-feldspar mineral ***-orthogneiss and amphibolite display a nematoblastic texture with an amphibole+(1)plagioclase+quartz+(1)titanite assemblage and an amphibole+(2)plagioclase+(2)titanite+ilmenite retrograde mineral *** calculated for the two sillimanite-garnet paragneiss samples show P-T peak conditions at~6-7.5 kbar and~725-740℃.The results for amphibole-orthogneiss and the amphibolite yield P-T peak conditions at~8.5-10 kbar and~690-710℃.The mode models imply that metasedimentary and metaigneous units can produce up to~20 vol%and~10 vol%of melt,*** within a closed system during isobaric heating suggests that melt compositions of metasedimentary and metaigneous units are likely to have direct implications for the petrogenesis of the Puerto Vallarta *** new data indicate that the Yelapa-Chimo Metamorphic Complex evolved through a metamorphic gradient between~23-33℃km^-1and the metamorphic rocks formed at depths between~22 km and~30 km with a burial rate of~2.0 km Ma^-***,the P-T data for both metasedimentary and metaigneous rocks provide new constraints on an accretionary framework,which is responsible for generating metamorphism and partial melting in the YelapaChimo Metamorphic Complex during the Early Cretaceous.

关键词： Phase equilibrium modelling Yelapa-Chimo Metamorphic Complex Amphibolite facies Partial melting

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Relationship between vegetation structure and microenvironment in Fagus grandifolia *** forest relicts in Mexico

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Journal of Plant Ecology 2018年第2期11卷 237-247页

作者： Ernesto ChRodríguez-Ramírez Arturo Sánchez-González GregorioÁngeles-Pérez laboratorio de Biogeografía y Sistemática Facultad de CienciasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMéxico laboratorio de Ecología de Poblaciones Centro de Investigaciones BiológicasUniversidad Autónoma del Estado de HidalgoCiudad UniversitariaCarretera Pachuca-Tulancingo Km.4.5Mineral de la Reforma 42184Hidalgo Postgrado en Ciencias Forestales Colegio de PostgraduadosMontecillo 56230TexcocoEstado de MéxicoMéxico

Aims Changes in the structure and composition of forests,whether caused by natural or anthropic events,alter the microenviron-ment,sometimes *** the local environment has a direct impact on basic ecological processes,this has become a key component of *** beech forests(Fagus grandi-folia ***)in the Sierra Madre Oriental are restricted to sites with specific climate,soils and topography,making them an ideal natural system for ecological *** objectives of this study were to identify the relationship between the microen-vironment and the tree and shrub structure and composition of Mexican beech forests in the state of Hidalgo,and to compare the floristic similarity of these forests on the country scale using data from seven *** Specimens were collected for a period of one year at all locali-ties in the state of Hidalgo where beech forests are *** each locality,five 400 m2 plots were established,and structural attributes(basal area,coverage,density and species richness)and six environmental variables were measured in the *** relationship between structure and microenvironment was estimated by simple correlation and canonic correspondence analysis(CCA).in addition,floristic similarity between different beech forest localities in the Sierra Madre Oriental was esti-mated by correspondence analysis(CA).Important Findings Twenty tree species and eight shrub species were identified;at all localities studied *** *** dominated the *** multivariate analysis indicated that(i)in the four localities in the state of Hidalgo,all microenvironmental variables except pH are related to the variation observed in species composition and structure;(ii)the El Gosco locality had both tree and shrub species and microenvironmental factors different from those observed in the Fagus forests at the other localities in the study and(iii)the localities studied in order to draw country-scale compa

关键词： Canonical correspondence analysis fagus forest floristic composition Mexico montane cloud forest richness

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Immunometabolic bases of type 2 diabetes in the severity of COVID- 19

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World Journal of Diabetes 2021年第7期12卷 1026-1041页

作者： Rebeca Viurcos-Sanabria Galileo Escobedo Research Division Hospital General de MéxicoMexico City 06720Mexico laboratorio de Proteómica Dirección de InvestigaciónHospital General de Mexico“Dr.Eduardo Liceaga”Mexico City 06720Mexico

The outbreak of coronavirus disease 2019(COVID-19)is caused by the novel severe acute respiratory syndrome coronavirus-2(SARS-CoV-2).COVID-19 and type 2 diabetes(T2D)have now merged into an ongoing global syndemic that is threatening the lives of millions of people around the *** this reason,there is a deep need to understand the immunometabolic bases of the main etiological factors of T2D that affect the severity of ***,we discuss how hyperglycemia contributes to the cytokine storm commonly associated with COVID-19 by stimulating monocytes and macrophages to produce interleukin IL-1β,IL-6,and TnF-αin the airway *** main mechanisms through which hyperglycemia promotes reactive oxygen species release,inhibition of T cell activation,and neutrophil extracellular traps in the lungs of patients with severe SARS-CoV-2 infection are also *** further examine the molecular mechanisms by which proinflammatory cytokines induce insulin resistance,and their deleterious effects on pancreaticβ-cell exhaustion in T2D patients critically ill with *** address the effect of excess glucose on advanced glycation end product(AGE)formation and the role of AGEs in perpetuating pneumonia and acute respiratory distress ***,we discuss the contribution of preexisting endothelial dysfunction secondary to diabetes in the development of neutrophil trafficking,vascular leaking,and thrombotic events in patients with severe SARS-CoV-2 *** we outline here,T2D acts in synergy with SARSCoV-2 infection to increase the progression,severity,and mortality of *** think a better understanding of the T2D-related immunometabolic factors that contribute to exacerbate the severity of COVID-19 will improve our ability to identify patients with high mortality risk and prevent adverse outcomes.

关键词： COVID-19 SARS-CoV-2 Type 2 diabetes Inflammation Hyperglycemia Prothrombotic state

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