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Factors Impacting Participatory Post‑Disaster Relocation and Housing Reconstruction:The Case of Tsholotsho District,Zimbabwe

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International Journal of Disaster Risk Science 2024年第1期15卷 58-72页

作者： Nombulelo Kitsepile Ngulube Hirokazu Tatano Subhajyoti Samaddar Department of Social Informatics Graduate School of InformaticsKyoto UniversityKyoto 606-8507Japan Disaster Prevention Research Institute(DPRI) Kyoto UniversityKyoto 611-0011Japan

Relocation is not typically considered the best planning option for post-disaster reconstruction and rehabilitation,but it may be necessary if the site has suffered severe damage or is at imminent *** is a growing recognition that strong community participation is necessary in the post-disaster relocation decision-making process since relocation can have detrimental effects on a community’s livelihood,cultural system,and way of life,among ***,the realization of this still needs to be *** of yet,few studies have examined a comprehensive account of meaningful community engagement in post-disaster relocation and reconstruction,particularly in developing *** study investigated what factors influenced local communities’ participation in post-disaster relocation and reconstruction works after the 2017Cyclone Dineo flood disaster in the Tsholotsho District of *** research methods such as face-to-face interviews,observations,and focus groups were used to collect qualitative data from a purposive sample of 25 community members and 6 *** empirical investigation showed that despite the fact that the relocation project was conceived as a community-centered project,there was no meaningful community engagement,due to the absence of a participatory framework or planning guidelines for stakeholder engagement,as well as the lack of political willingness among government *** study concluded that the lack of community involvement led to local communities abandoning the reconstruction sites because relocation projects failed to accommodate the cultural beliefs,place attachments,and livelihood concerns of local *** study suggested that it is imperative to enhance the awareness of government officials and other stakeholders about the importance of community participation for the effective implementation of post-disaster relocation *** community participation can also provide avenues fo

关键词： Community rehabilitation Housing reconstruction-Participatory relocation Zimbabwe

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Zn Dissolution-Passivation Behavior with ZnO Formation via In Situ Characterizations

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Energy & Environmental Materials 2024年第1期7卷 197-204页

作者： Tanyanyu Wang Masahiro Kunimoto Masahiro Yanagisawa Masayuki Morita Takeshi Abe Takayuki Homma Graduate School of Advanced Science and Engineering Waseda University Office of Society-Academia Collaboration for Innovation Kyoto University Graduate School of Engineering Kyoto University Kyoto daigaku-katsura

In this study,ZnO formation during the dissolution-passivation process of Zn anodes is observed via in situ Raman and optical *** Zn passivation during galvanostatic anodization merely follows the dissolution-precipitation model,whereas that of potentiodynamic polarization exhibits different behaviors in different potential ranges.

关键词： in situ characterization Zn dissolution and passivation ZnO formation

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Stage at diagnosis of colorectal cancer through diagnostic route:Who should be screened?

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World Journal of Gastroenterology 2024年第10期30卷 1368-1376页

作者： Nobukazu Agatsuma Takahiro Utsumi Yoshitaka Nishikawa Takahiro Horimatsu Takeshi Seta Yukitaka Yamashita Yukari Tanaka Takahiro Inoue Yuki Nakanishi Takahiro Shimizu Mikako Ohno Akane Fukushima Takeo Nakayama Hiroshi Seno Department of Gastroenterology and Hepatology Kyoto University Graduate School of MedicineKyoto 606-8507Japan Department of Gastroenterology and Hepatology Japanese Red Cross Wakayama Medical CenterWakayama 640-8558Japan Department of Health Informatics Kyoto University School of Public HealthKyoto 606-8501Japan Institute for Advancement of Clinical and Translational Science(iACT) Kyoto University HospitalKyoto 606-8507Japan Medical Support Section Medical Affairs DivisionKyoto University HospitalKyoto 606-8507Japan

BACKGROUND Colorectal cancer(CRC)is a global health concern,with advanced-stage diagnoses contributing to poor *** efficacy of CRC screening has been well-established;nevertheless,a significant proportion of patients remain unscreened,with>70%of cases diagnosed outside *** identifying specific subgroups for whom CRC screening should be particularly recommended is crucial owing to limited resources,the association between the diagnostic routes and identification of these subgroups has been less *** the Japanese cancer registry,the diagnostic routes for groups discovered outside of screening are primarily categorized into those with comorbidities found during hospital visits and those with CRC-related *** To clarify the stage at CRC diagnosis based on diagnostic *** We conducted a retrospective observational study using a cancer registry of patients with CRC between January 2016 and December 2019 at two *** diagnostic routes were primarily classified into three groups:Cancer screening,follow-up,and *** early-stage was defined as Stages 0 or *** and univariate logistic regressions were exploited to determine the odds of early-stage diagnosis in the symptomatic and cancer screening groups,referencing the follow-up *** adjusted covariates were age,sex,and tumor *** Of the 2083 patients,715(34.4%),1064(51.1%),and 304(14.6%)belonged to the follow-up,symptomatic,and cancer screening groups,*** the 2083 patients,CRCs diagnosed at an early stage were 57.3%(410 of 715),23.9%(254 of 1064),and 59.5%(181 of 304)in the follow-up,symptomatic,and cancer screening groups,*** symptomatic group exhibited a lower likelihood of early-stage diagnosis than the follow-up group[P<0.001,adjusted odds ratio(aOR),0.23;95%confidence interval(95%CI):0.19-0.29].The likelihood of diagnosis at an early stage was similar between the follow-up and cancer screening gro

关键词： Colorectal neoplasms Cancer registry Diagnostic route Cancer screening Stage at diagnosis

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Joint input–output identiﬁcation of unstable systems with kernel regularization

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Control Theory and Technology 2024年第2期22卷 195-202页

作者： Yusuke Fujimoto Toshiharu Sugie Department of Environmental Engineering the University of Kitakyushu1-1HibikinoWakamatsu-kuKitakyushu 8080135FukuokaJapan Professor Emeritus Kyoto UniversityYoshida-HonmachiSakyo-kuKyoto 6068501KyotoJapan

This paper discusses closed-loop identiﬁcation of unstable *** particular,weﬁrst apply the joint input–output identiﬁcation method and then convert the identiﬁcation problem of unstable systems into that of stable systems,which can be tackled by using kernel-based regularization *** propose to identify two transfer functions by kernel regularization,the one from the reference signal to the input,and the one from the reference signal to the *** these transfer functions are stable,kernel regularization methods can construct their accurate *** the model of unstable system is constructed by ratio of these *** effectiveness of the proposed method is demonstrated by a numerical example and a practical experiment with a DC motor.

关键词： Closed-loop identification Kernel regularization Joint input-output identification

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Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins

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World Journal of Gastroenterology 2006年第19期12卷 3031-3037页

作者： Kazuhiro Fukushima Yoko Aoi Shinichi Kato Koji Takeuchi Department of Pharmacology and Experimental Therapeutics kyoto Pharmaceutical University MisasagiYamashinaKyoto 607-8414Japan

AIM： Lafutidine, a histamine H2 receptor antagonist, exhibits gastro-protective action mediated by capsaicinsensitive afferent neurons （CSN）. We compared the effect between lafutidine and capsaicin, with respect to the interaction with endogenous prostaglandins （PG）, nitric oxide （NO） and the afferent neurons, including transient receptor potential vanilloid subtype 1 （TRPV1）. METHODS： Male SD rats and C57BL/6 mice, both wildtype and prostacyclin IP receptor knockout animals, were used after 18 h of fasting. Gastric lesions were induced by the po administration of HCl/ethanol （60% in 150 mmol/L HCl） in a volume of 1 mL for rats or 0.3 mL for mice. RESULTS： Both lafutidine and capsaicin （1-10 mg/kg, po） afforded dose-dependent protection against HCI/ ethanol in rats and mice. The effects were attenuated by both the ablation of CSN and pretreatment with NG-nitro- L-arginine methyl ester, yet only the effect of capsaicin was mitigated by prior administration of capsazepine, the TRPV1 antagonist, as well as indomethacin. Lafutidine protected the stomach against HCl/ethanol in IP receptor knockout mice, similar to wild-type animals, while capsaicin failed to afford protection in the animals lacking IP receptors. Neither of these agents affected the mucosal PGE2 or 6-keto PGF1α contents in rat stomachs. Capsaicin evoked an increase in [Ca^2＋]i in rat TRPV1-transfected HEK293 cells while lafutidine did not. CONCLUSION： These results suggest that although both lafutidine and capsaicin exhibit gastro-protective action mediated by CSN, the mode of their effects differs regarding the dependency on endogenous PGs/IP receptors and TRPV1. It is assumed that lafutidine interacts with CSN at yet unidentified sites other than TRPV1.

关键词： Lafutidine A histamine H2-receptor antagonist Gastric protection Prostaglandin Capsaicin-sensirive afferent neuron TRPVt

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Pathogenesis of NSAID-induced gastric damage:Importance of cyclooxygenase inhibition and gastric hypermotility

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World Journal of Gastroenterology 2012年第18期18卷 2147-2160页

作者： Koji Takeuchi Department of Pharmacology and Experimental Therapeutics Division of Pathological SciencesKyoto Pharmaceutical UniversityKyoto 607-8414Japan

This article reviews the pathogenic mechanism of nonsteroidal anti-inflammatory drug(NSAID)-induced gastric damage,focusing on the relation between cyclooxygenase(COX) inhibition and various functional ***,such as indomethacin,at a dose that inhibits prostaglandin(PG) production,enhance gastric motility,resulting in an increase in mucosal permeability,neutrophil infiltration and oxyradical production,and eventually producing gastric *** lesions are prevented by pretreatment with PGE 2 and antisecretory drugs,and also via an atropine-sensitive mechanism,not related to antisecretory *** neither rofecoxib(a selective COX-2 inhibitor) nor SC-560(a selective COX-1 inhibitor) alone damages the stomach,the combined administration of these drugs provokes gastric ***-560,but not rofecoxib,decreases prostaglandin E 2(PGE 2) production and causes gastric hypermotility and an increase in mucosal ***-2 mRNA is expressed in the stomach after administration of indomethacin and SC-560 but not *** up-regulation of indomethacin-induced COX-2 expression is prevented by atropine at a dose that inhibits gastric *** addition,selective COX-2 inhibitors have deleterious influences on the stomach when COX-2 is overexpressed under various conditions,including adrenalectomy,arthritis,and Helicobacter *** summary,gastric hypermotility plays a primary role in the pathogenesis of NSAID-induced gastric damage,and the response,causally related with PG deficiency due to COX-1 inhibition,occurs prior to other pathogenic events such as increased mucosal permeability;and the ulcerogenic properties of NSAIDs require the inhibition of both COX-1 and COX-2,the inhibition of COX-1 upregulates COX-2 expression in association with gastric hypermotility,and PGs produced by COX-2 counteract the deleterious effect of COX-1 inhibition.

关键词： Non-steroidal anti-inflammatory drug Gastric damage Pathogenesis Gastric motility Neutrophil

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Product Form Solution of a Queuing-Inventory System with Lost Sales and Server Vacation

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Journal of Systems Science & Complexity 2024年第2期37卷 729-758页

作者： YUE Dequan ZHANG Yuying XU Xiuli YUE Wuyi School of Science Yanshan UniversityQinhuangdao 066004China School of Economics and Management Yanshan UniversityQinhuangdao 066004China The kyoto College of Graduate Studies for Informatics Kyoto City 606-8225Japan

In this study,the authors consider an M/M/1 queuing system with attached inventory under an(s,S)control *** server takes multiple vacations whenever the inventory is *** is assumed that the lead time and the vacation time follow exponential *** authors formulate the model as a quasi-birth-and-dearth(QBD)process and derive the stability condition of the ***,the stationary distribution in product form for the joint process of the queue length,the inventory level,and the server’s status is ***,the conditional distributions of the inventory level when the server is on and operational,and when it is off due to a vacation,are *** the stationary distribution,the authors obtain some performance measures of the *** authors investigate analytically the effect of the server’s vacation on the performance ***,several numerical examples are presented to investigate the effects of some parameters on the performance measures,the optimal policy,and the optimal cost.

关键词： Cost function multiple vacations product form solution queuing-inventory system (s S)control policy

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Reactions of Benzo[b]cyclobuta[d]pyran-3-one Derivatives with Sulfur Ylide

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复旦学报（自然科学版） 2005年第5期44卷 895-896页

作者： Masayuki Yamashita Yadav Navnath D. Masaki Nagahama Tomoki Inaba Ikuo Kawasaki Shunsaku Ohta kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku Kyoto 607-8414 JapanKyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku Kyoto 607-8414 JapanKyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku Kyoto 607-8414 JapanKyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku Kyoto 607-8414 JapanKyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku Kyoto 607-8414 JapanKyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku Kyoto 607-8414 Japan

Small ring size cycloalkanes such as cyclopropanes and cyclobutanes have been found as a basic structuralconstituent in a wide rang of natural products[1]. In organic synthesis, their cycloalkanes also play an impor-t... 详细信息

关键词：立体收敛反应光化学叶立德加氢催化吡喃

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Reactions of Benzo[b]cyclobuta[d]pyran-3-one Derivatives with Sulfur Ylide

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复旦学报(自然科学版) 2005年第5期 285-286页

作者： Masayuki Yamashita,Yadav Navnath D.,Masaki Nagahama,Tomoki Inaba,Ikuo Kawasaki,Shunsaku Ohta kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku kyoto 607-8414 Japan kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku kyoto 607-8414 Japan kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku kyoto 607-8414 Japan kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku kyoto 607-8414 Japan kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku kyoto 607-8414 Japan kyoto Pharmaceutical University Misasagi-Nakauchicho 5 Yamashinaku kyoto 607-8414 Japan

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New method of local adjuvant therapy with bicarbonate Ringer’s solution for tumoral calcinosis: A case report

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World Journal of Orthopedics 2024年第3期15卷 302-309页

作者： Takashi Noguchi Akio Sakamoto Kensaku Kakehi Shuichi Matsuda Department of Orthopaedic Surgery Graduate School of MedicineKyoto UniversityKyoto 606-8507Japan

BACKGROUND Tumoral calcinosis is a condition characterized by deposits of calcium phosphate crystals in extra-articular soft tissues,occurring in hemodialysis *** phosphate crystals are mainly composed of hydroxyapatite,which is highly infilt-rative to tissues,thus making complete resection *** adjuvant method to remove or resolve the residual crystals during the operation is *** SUMMARY A bicarbonate Ringer’s solution with bicarbonate ions(28 mEq/L)was used as the *** resecting calcium phosphate deposits of tumoral calcinosis as much as possible,while filling with the solution,residual calcium phosphate deposits at the pseudocyst wall can be gently scraped by fingers or gauze in the operative field.A 49-year-old female undergoing hemodialysis for 15 years had swelling with calcium deposition for 2 years in the shoulders,bilateral hip joints,and the right foot.A shoulder lesion was resected,but the calcification remained and early re-deposition was *** the difficulty of a complete rection,we devised a bicarbonate dissolution method and excised the foot *** resection of the calcified material,the residual calcified material was washed away with bicarbonate Ringer’s *** The bicarbonate dissolution method is a new,simple,and effective treatment for tumoral calcinosis in hemodialysis patients.

关键词： Tumoral calcinosis Adjuvant therapy Bicarbonate Ringer’s solution Surgery Case report

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