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A Structured Method of Teaching Epidural Block reduces the incidence of accidental dural puncture in inexperienced trainees.

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Open Journal of Anesthesiology 2024年第4期14卷 131-135页

作者： Marco Scorzoni Gianluigi Gonnella Emanuele Capogna Marina Campione Gaetano Draisci Matteo Velardo Giorgio Capogna Department of Anesthesiology Fondazione Policlinico Gemelli IRCCS Rome Italy Department of Economics and Law Enna Kore University Enna Italy European School of Obstetric Anesthesia Rome Italy

Background: The rate of accidental dural puncture is particularly high during the period of training, especially in novices. The structured epidural teaching model (SETM) includes three standardized video lessons, the construction of a 3D epidural module by trainees and practical training by using an epidural simulator with and without the CompuFlo™ Epidural instrument. In this study we report the retrospective analysis of the accidental dural puncture rate of inexperienced trainees during their 6 months clinical practice rotation in obstetrics before and after the introduction of the SETM in our Institution. Method: We evaluated the incidence of accidental dural puncture before the introduction of the SETM methodology and afterwards by analyzing our departmental database from February 2019 to January 2023. All epidural blocks were executed by trainees who had never previously performed an epidural block and were about to begin their obstetrics rotation. Results: We analyzed 7415 epidurals: 3703 were performed before the introduction of the SETM methodology (control group) and 3712 afterwards (study group). The incidence of accidental dural puncture was 0.37% for the control group and 0.13% for the study group (p<.05). The probability of making an accidental dural puncture was 64% (OR: 0.36) lower for trainees who had the training than for those who did not. Conclusions: After the introduction of the structured teaching method, we observed a significant reduction of accidental dural puncture during the training period. We hope that our observation will encourage a constructive discussion among experts about the need to use standardized and validated tools as a valuable aid in teaching epidural anesthesia.

关键词： teaching epidural Anesthesia obstetrical Anesthesia Anesthesia

Metastatic clear cell sarcoma of the pancreas:A sporadic cancer

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World Journal of Clinical Cases 2024年第18期12卷 3291-3294页

作者： Vittorio Gebbia Carlo Carnaghi Department of Medical Oncology Faculty of MedicineUniversity of Enna“Kore”Enna 94100Italy Medical Oncology Unit Cdc TorinaPalermo 90145Italy Medical Oncology Unit Humanitas Istituto Clinico CataneseMisterbiancoCatania 95045Italy

Primary or secondary clear cell sarcoma of the pancreas is an exceedingly rare and aggressive *** addition to pathology,molecular analysis is pivotal in differential diagnosis,especially with malignant melanoma.A key aspect in identifying clear cell sarcoma is specific genetic alterations,notably the translocation of t(12;22)(q13;q13),a diagnostic hallmark of this sarcoma subtype,which is absent in malignant *** of primary clear cell sarcoma of the pancreas is the same as that for adenocarcinoma.

关键词： Clear cell sarcoma Pancreas Rare cancer Metastatic Diagnosis

Femtosecond Tm-Ho co-doped fiber laser using a bulk-structured Bi2Se3 topological insulator

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Chinese Physics B 2018年第9期27卷 137-143页

作者： Jinho Lee Ju Han Lee School of Electrical and Computer Engineering University of SeoulSeoul 02504Republic of Kore

We experimentally demonstrate a femtosecond mode-locked thulium-holmium（Tm-Ho） co-doped fiber laser incorporating a saturable absorber（SA） based on a bulk-structured bismuth selenide（Bi2Se3） topological insulator（TI）. The SA was prepared by depositing a mechanically exfoliated Bi2Se3 TI layer onto a side-polished optical fiber platform. Unlike high-quality nano-structured Bi2Se3 TI-based SA, bulk-structured Bi2Se3 with non-negligible oxidation was used as a saturable absorption material for this experimental demonstration due to its easy fabrication process. The saturation power and modulation depth of the prepared SA were measured to be -28.6 W and -13.4%, respectively. By incorporating the prepared SA into a Tm-Ho co-doped fiber ring cavity, stable soliton pulses with a temporal width of - 853 fs could be generated at 1912.12 nm. The 3-dB bandwidth of the mode-locked pulse was measured to be -4.87 nm. This experimental demonstration reaffirms that Bi2Se3 is a superb base material for mid-infrared passive mode-locking even under oxidation.

关键词： topological insulator mode-locked lasers femtosecond pulse fiber lasers

Passively Q-switched ytterbium-doped fiber laser using the evanescent field interaction with bulk-like WTe_2 particles

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Chinese Optics Letters 2018年第2期16卷 108-112页

作者： Seunghwan Ko Jinho Lee Ju Han Lee School of Electrical and Computer Engineering University of Seoul Seoul 02504 Republic of Kore

The potential of bulk-like WTe2 particles for the realization of a passive Q-switch operating at the 1 μm wavelength was investigated. The WTe2 particles were prepared using a simple mechanical exfoliation method together with Scotch tape. By attaching bulk-like WTe2 particles, which remained on the top of the sticky surface of a small segment of the Scotch tape, to the flat side of a side-polished fiber, a saturable absorber（SA） was readily implemented. A strong saturable absorption was then readily obtained through an evanescent field interaction with the WTe2 particles. The modulation depth of the prepared SA was measured as ~2.18% at 1.03 μm. By incorporating the proposed SA into an all-fiberized ytterbium-doped fiber ring cavity, stable Qswitched pulses were readily achieved.

关键词： length Passively Q-switched ytterbium-doped fiber laser using the evanescent field interaction with bulk-like WTe2 particles SA

Whole-eye transplantation: Current challenges and future perspectives

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World Journal of Transplantation 2024年第2期14卷 28-39页

作者： Anna Scarabosio Pier Luigi Surico Vlad Tereshenko Rohan Bir Singh Carlo Salati Leopoldo Spadea Glenda Caputo Pier Camillo Parodi Caterina Gagliano Jonathan M Winograd Marco Zeppieri Department of Plastic Surgery University Hospital of UdineUdine 33100Italy Department of Plastic Surgery Massachusetts General HospitalHarvard Medical SchoolBostonMA 02114United States Schepens Eye Research Institute of Mass Eye and Ear Harvard Medical SchoolBostonMA 02114United States Department of Ophthalmology University Hospital of UdineUdine 33100Italy Eye Clinic Policlinico Umberto I"Sapienza"University of RomeRome 00142Italy Department of Medicine and Surgery University of Enna"Kore"Enna 94100Italy Eye Clinic Catania University San Marco Hospital Viale Carlo Azeglio Ciampi 95121 CataniaItaly

Whole-eye transplantation emerges as a frontier in ophthalmology,promising a transformative approach to irreversible *** advancements,formidable challenges *** of donor eye viability post-enucleation necessitates meticulous surgical techniques to optimize retinal integrity and ganglion cell *** the inhibitory milieu of the central nervous system for successful optic nerve regeneration remains elusive,prompting the exploration of neurotrophic support and immunomodulatory *** tolerance,paramount for graft acceptance,confronts the distinc-tive immunogenicity of ocular tissues,driving research into targeted immunosup-pression *** and legal considerations underscore the necessity for stringent standards and ethical *** collaboration and ongoing research endeavors are imperative to navigate these ***,stem cell therapies,and precision immunomodulation represent promising avenues in this ***,the aim of this review is to critically assess the current landscape of whole-eye transplantation,elucidating the challenges and advancements while delineating future directions for research and clinical *** concerted efforts,whole-eye transplantation stands to revolu-tionize ophthalmic care,offering hope for restored vision and enhanced quality of life for those afflicted with blindness.

关键词： Eye Transplantation Optic nerve Nerve regeneration Immunological tolerance

When Edge Computing Meets IoT Systems: Analysis of Case Studies

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China Communications 2020年第10期17卷 50-63页

作者： Fabio Arena Giovanni Pau Faculty of Engineering and Architecture Kore University of EnnaCittadella UniversitariaEnna 94100Italy

On a macroscopic level,an edge computing architecture looks like a distributed and decentralized IT(Information Technology)*** in detail,it could be defined as a mesh network of micro data centers capable of processing and storing critical data locally,and to transmit all data received and/or processed to a central data center or a cloud storage *** network topology,also taking advantage of the availability on the market of cost-effective small form factor(SFF)electronic components and systems decreasing,brings the essential components of processing,storage,and networking closer to the sources that generate the *** typical use case is that of Internet of Things(IoT)devices and implementations,which often face latency problems,lack of bandwidth,reliability,which cannot be addressed through the conventional cloud *** this context,the edge computing architecture can reduce the size of data to be sent to the cloud,processing critical data,sensitive to latency,at the point of origin,via a smart device,or sending it to an intermediate server,located *** aim of this paper is to report some of the main aspects and significant features of edge computing and analyzing several popular case studies.

关键词： edge computing fog computing cloud computing analysis internet of things

A quaternion-based simulation of multirotor dynamics

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International Journal of Modeling, Simulation, and Scientific Computing 2015年第1期6卷 145-162页

作者： Valeria Artale Cristina L.R.Milazzo Angela Ricciardello kore.University of Enna Faculty of Engineering and Architecture Cittadella Universitaria 94100EnnaItaly

The main problem addressed in this paper is the quaternion-based trajectory control of a microcopter consisting of six rotors with three pairs of counter-rotating fixed-pitch blades,known as *** the hypothesis of rigid body condition is assumed,the Newton–Euler equations describe the translational and rotational motion of the *** standard Euler-angle parametrization of three-dimensional rotations contains singular points in the coordinate space that can cause failure of both dynamical model and *** order to avoid singularities,all the rotations of the microcopter are thus parametrized in terms of quaternions and an original proportional derivative(PD)regulator is proposed in order to control the dynamical *** simulations will be performed on symmetrical flight configuration,proving the reliability of the proposed PD control technique.

关键词： Newton-Euler equation quaternion UAV control

Blockchain and Machine Learning for Intelligent Multiple Factor-Based Ride-Hailing Services

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Computers, Materials & Continua 2022年第3期70卷 4429-4446页

作者： Zeinab Shahbazi Yung-Cheol Byun IIST Department of Computer EngineeringJeju National UniversityJeju-siJeju Special Self-Governing Province63243Kore

One of the common transportation systems in kore. is calling taxis through online applications,which is more convenient for passengers and drivers in the modern ***,the driver’s passenger taxi request can be rejected based on the driver’s location and ***,there is a need to specify driver’s acceptance and rejection of the received *** security of this systemis anothermain core to save the transaction information and safety of passengers and *** this study,the origin and destination of the Jeju island Southkore. were captured from T-map and processed based on machine learning decision tree and XGBoost *** blockchain framework is implemented in the Hyperledger Fabric *** experimental results represent the features of *** cross-validation was *** is another factor for the taxi trip,which in total trip in midnight is quite *** process presents the successful matching of ride-hailing taxi services with the specialty of distance,the trip request,and safety based on the total city measurement.

关键词： Taxi trip blockchain machine learning ride-hailing prediction trip distance

Analysis of the current density characteristics in through-mask electrochemical micromachining(TMEMM) for fabrication of micro-hole arrays on invar alloy film

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Chinese Journal of Aeronautics 2017年第3期30卷 1231-1241页

作者： Da-som JIN Kwang-ho CHUN Eun-sang LEE School of Mechanical Engineering Inha University Incheon 22212 Republic of Kore Department of Mechanical Engineering Inha University Incheon 22212 Republic of Korea

Invar alloy consisting of 64% iron and 36% nickel has been widely used for the production of shadow masks for organic light emitting diodes（OLEDs） because of its low thermal expansion coefficient（1.86 × 10^-6cm/°C）.To fabricate micro-hole arrays on 30 lm invar alloy film,through-mask electrochemical micromachining（TMEMM） was developed and combined with a portion of the photolithography etching *** precise hole shapes,patterned photoresist（PR） film was applied as an insulating *** investigate the relationship between the current density and the material removal rate,the principle of the electrochemical machining was studied with a focus on the *** finite element method（FEM） was used to verify the influence of each parameter on the current density on the invar alloy film *** parameters considered were the thickness of the PR mask,inter-electrode gap（IEG）,and electrolyte *** of experiments（DOE） was used to figure out the contribution of each parameter.A simulation was conducted with varying parameters to figure out their relationships with the current *** was conducted to select the suitable *** experiment was carried out to verify the simulation *** was possible to fabricate micro-hole arrays on invar alloy film using TMEMM,which is a promising method that can be applied to fabrications of OLEDs shadow masks.

关键词： Electrochemical Invar alloy film Micromachining OLED shadow mask Photoresist film mask(PR film mask) Through-mask electrochemical micromachining(TMEMM)