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Genes & Diseases 2024年第3期11卷 98-101页

作者： Zishuai Wang Yilong Yao Xinhua Hou Danyang Fan Yanwen Liu Adeyinka Abiola Adetula Yalan Yang kui Li Zhonglin Tang Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenGuangdong518000China Kunpeng Institute of Modern Agriculiture at Foshan Chinese Academy of Agricultural SciencesFoshanGuangdong528226China GuangXi Engineering centre for Resource Development of Bama Xiang Pig BamaGuangxi 547500China Institute of Animal science Chinese Academy of Agricultural SciencesBeijing100193China

Aerobic exercise training alters gene expression in skeletal muscle,and miRNAs significantly contribute to motion ***,the molecular mechanisms by which miRNAs regulate the response to exercise training are not well ***,we found that the abundance of miR-378a-3p in skeletal muscle significantly decreased after exercise ***-378a-3p knockout mice showed increased insulin sensitivity,insulin-mediated glucose uptake.

关键词： skeletal miR uptake

Prospects of the Multi-channel Photometric Survey Telescope in the Cosmological Application of Type Ia Supernovae

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Research in Astronomy and Astrophysics 2024年第4期24卷 183-191页

作者： Zhenyu Wang Jujia Zhang Xinzhong Er Jinming Bai Yunnan Observatories Chinese Academy of SciencesKunming 650216China University of Chinese academy of sciences Beijing 100049China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China International centre of Supernovae Yunnan Key LaboratoryKunming 650216China South-Western Institute for Astronomy Research Yunnan UniversityKunming 650500China

The Multi-channel Photometric Survey Telescope(Mephisto)is a real-time,three-color photometric system designed to capture the color evolution of stars and transients *** telescope system can be crucial in cosmological distance measurements of low-redshift(low-z,z■0.1)Type Ia supernovae(SNe Ia).To optimize the capabilities of this instrument,we perform a comprehensive simulation study before its official operation is scheduled to *** considering the impact of atmospheric extinction,weather conditions,and the lunar phase at the observing site involving the instrumental features,we simulate light curves of SNe Ia obtained by *** best strategy in the case of SN Ia cosmology is to take the image at an exposure time of 130 s with a cadence of 3 *** this condition,Mephisto can obtain hundreds of high-quality SNe Ia to achieve a distance measurement better than 4.5%.Given the on-time spectral classification and monitoring of the Lijiang 2.4 m Telescope at the same observatory,Mephisto,in the whole operation,can significantly enrich the well-calibrated sample of supernovae at low-z and improve the calibration accuracy of high-z SNe Ia.

关键词： (stars:)supernovae:general (cosmology:)cosmological parameters telescopes

Dimensionality-driven metal to Mott insulator transition in two-dimensional 1T-TaSe2

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National science Review 2024年第3期11卷 108-118页

作者： Ning Tian Zhe Huang Bo Gyu Jang Shuaifei Guo Ya-Jun Yan Jingjing Gao Yijun Yu Jinwoong Hwang Cenyao Tang Meixiao Wang Xuan Luo Yu Ping Sun Zhongkai Liu Dong-Lai Feng Xianhui Chen Sung-Kwan Mo Minjae Kim Young-Woo Son Dawei Shen Wei Ruan Yuanbo Zhang State Key Laboratory of Surface Physics New Cornerstone Science Laboratory and Department of PhysicsFudan University Shanghai Qi Zhi Institute Shanghai Research Center for Quantum sciences Institute for Nanoelectronic Devices and Quantum Computing Fudan University Zhangjiang Fudan International Innovation Center Fudan University State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology(SIMIT)Chinese Academy of Sciences School of Physical science and Technology ShanghaiTech University Korea Institute for Advanced Study School of Emerging Technology and Department of Physics University of Science and Technology of China Advanced Light Source Lawrence Berkeley National Laboratory ShanghaiTech Laboratory for Topological Physics Key Laboratory of Materials Physics Institute of Solid State Physics Hefei Institutes of Physical ScienceChinese Academy of Sciences High Magnetic Field Laboratory Hefei Institutes of Physical Science Chinese Academy of Sciences Collaborative Innovation centre of Advanced Microstructures Nanjing University Department of Physics University of Science and Technology of China and Key Laboratory of Strongly Coupled Quantum Matter Physics Chinese Academy of Sciences National Synchrotron Radiation Laboratory University of Science and Technology of China

Two-dimensional materials represent a major frontier for research into exotic many-body quantum phenomena. In the extreme two-dimensional limit, electron-electron interaction often dominates over other electronic energy scales, leading to strongly correlated effects such as quantum spin liquid and unconventional *** dominance is conventionally attributed to the lack of electron screening in the third dimension. Here, we discover an intriguing metal to Mott insulator transition in 1T-TaSe2that defies conventional wisdom. Specifically, we find that dimensionality crossover, instead of reduced screening, drives the transition in atomically thin 1T-TaSe2. A dispersive band crossing the Fermi level is found to be responsible for the bulk metallicity in the material. Reducing the dimensionality,however, effectively quenches the kinetic energy of these initially itinerant electrons, and drives the material into a Mott insulating *** dimensionality-driven metal to Mott insulator transition resolves the long-standing dichotomy between metallic bulk and insulating surface of 1T-TaSe2. Our work further reveals a new pathway for modulating two-dimensional materials that enables exploring strongly correlated systems across uncharted parameter space.

关键词： two-dimensional materials 1T-TaSe2 dimensionality crossover metal to Mott insulator transition

Design of Biologically Active Macromolecular Ligands and Their Luminescent Complexes with Terbium Ions

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Chinese Journal of Polymer science 2024年第5期42卷 604-611,I0007页

作者： Tatiana N.Nekrasova Andrei I.Fischer Natalia A.Nesterova Anatoliy V.Dobrodumov Anzhelika V.Garshinina Olga D.Shuvaeva Natalya V.Zakharova Evgenii F.Panarin Institute of Macromolecular Compounds Russian Academy of Sciences31 Bolshoy pr.St Petersburg199004Russia Smorodintsev Research Institute of Influenza Russian Ministry of Health15/17 ul.prof.PopovaSt Petersburg197376Russia

Water-soluble copolymers of p-methacrylamidobenzoic acid(MABA)with neutral comonomers(N-vinylpyrrolidone(VP),N-methyl-N-vinylacetamide(MVAA),N-methacryloyl glucosamine(MAG))and anionic comononer sodium styrene sulfonate(NaSS)were synthesized by radical *** interactions between the prepared copolymers and Tb^(3+)ions in aqueous solutions were studied;the significant influence of chemical structure of a comonomer on luminescence intensity of Tb^(3+)complexes with the copolymers was *** luminescence intensity of Tb^(3+)complexes with the copolymers containing N-vinylamide units(VP,MVAA)is three times more intense than that observed for the complexes between Tb^(3+)and MAG-containing *** the case of NaSS-containing copolymers,the luminescence intensity is controlled by the values of binding constants between Tb^(3+)and MABA and the content of MABA units in a *** studied copolymers and their complexes with Tb^(3+)have low cytotoxicity and a pronounced antiviral activity against human respiratory syncytial virus.

关键词： Luminescence Water-soluble copolymers Lanthanide complexes Antiviral activity Cytotoxicity

Stable,intense supercontinuum light generation at 1 kHz by electric field assisted femtosecond laser filamentation in air

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Light(science & Applications) 2024年第2期13卷 354-365页

作者： Yaoxiang Liu Fukang Yin Tie-Jun Wang Yuxin Leng Ruxin Li Zhizhan Xu See Leang Chin State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine Mechanics and CAS Center for Excellence in Ultra-intense Laser ScienceChinese Academy of SciencesShanghaiChina Center of Materials science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijingChina centre d’Optique Photonique et Laser(COPL)and Département de physiquede génie physique et d’optiqueUniversitéLavalQuébecQuébecCanada

Supercontinuum(SC)light source has advanced ultrafast laser spectroscopy in condensed matter science,biology,physics,and *** to the frequently used photonic crystal fibers and bulk materials,femtosecond laser filamentation in gases is damage-immune for supercontinuum generation.A bottleneck problem is the strong jitters from filament induced self-heating at kHz repetition rate *** demonstrated stable kHz supercontinuum generation directly in air with multiple mJ level pulse *** was achieved by applying an external DC electric field to the air plasma *** pointing jitters of the 1 kHz air filament induced SC light were reduced by more than 2 *** stabilized high repetition rate laser filament offers the opportunity for stable intense SC generation and its applications in air.

关键词： intense repetition light

A likely paleo-autotetraploidization event shaped the high conservation of Nyssaceae genome

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Horticultural Plant Journal 2024年第3期10卷 911-930页

作者： Yishan Feng Zhenyi Wang Qimeng Xiao Jia Teng Jianyu Wang Zijian Yu Jiaqi Wang Qiang Xu Yan Zhang Shaoqi Shen Shoutong Bao Yu Li Zimo Yan Yue Ding Zihan Liu Yuxian Li Tianyu Lei Min Yuan Xiu-Qing Li Jinpeng Wang Department of Bioinformatics School of Life SciencesNorth China University of Science and TechnologyTangshanHebei 063000China Fredericton Research and Development centre Agriculture and Agri-Food CanadaFrederictonNew Brunswick E3B 4Z7Canada State Key Laboratory of Systematic and Evolutionary Botany Institute of BotanyChinese Academy of ScienceBeijing 100093China University of Chinese academy of sciences Beijing 100049China

Scientific knowledge about the ancestral genome of core eudicot plant kingdom can potentially have profound impacts on both basic and applied research,including evolution,genetics,genomics,ecology,agriculture,forestry,and global *** investigate which plant conserves best the core eudicots common ancestor genome,we compared Arcto-Tertiary relict Nyssaceae and 30 other eudicot plant *** genomes of Davidia involucrata(a known living fossil),Camptotheca acuminata and Nyssa sinensis,one per existent genus of Nyssaceae,were performed comparative genomic *** found that Nyssaceae originated from a single Nyssaceae common tetraploidization event(NCT)-autotetraploidization 28-31 Mya after the core eudicot common hexaploidization(ECH).We identified Nyssaceae orthologous and paralogous genes,determined its chromosomal evolutionary trajectory,and reconstructed the Nyssaceae most recent ancestor *** genome contained the entire seven paleochromosomes and 17 ECH-generated eudicot common ancestor chromosomes and was the slowest in mutation among the analyzed 42 species of 31 plant *** both its high retention of paleochromosomes and its low mutation rate,*** provides the best case in conservation of the core eudicot paleogenome.

关键词： Nyssaceae Polyploidization Multigenome alignment Evolutionary rate Autotetraploidization Karyotype evolution

Probing the Nucleation and Growth Kinetics of Bismuth Nanoparticles via In-situ Transmission Electron Microscopy

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Journal of Wuhan University of Technology(Materials science) 2024年第4期39卷 877-887页

作者：王浪李超凡 RAN Maojin YUAN Manman 胡执一 LI Yu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Nanostructure Research centre(NRC) Wuhan University of TechnologyWuhan 430070China Institute of Chemistry Henan Academy of SciencesZhengzhou 450002China Henan academy of sciences Zhengzhou 450046China

The nucleation and growth mechanism of nanoparticles is an important theory,which can guide the preparation of ***,it is still lacking in direct observation on the details of the evolution of intermediate state structure during nucleation and *** this work,the evolution process of bismuth nanoparticles induced by electron beam was revealed by in-situ transmission electron microscopy(TEM)at atomic *** experimental results demonstrate that the size,stable surface and crystallographic defect have important influences on the growth of Bi *** non-classical growth paths including single crystal growth and polycrystalline combined growth,as well as,corresponding layer-by-layer growth mechanism along{012}stable crystal plane of Bi nanoparticles with dodecahedron structure were revealed by in-situ TEM *** results provide important guidance and a new approach for in-depth understanding of the nucleation and growth kinetics of nanoparticles.

关键词： bismuth nanoparticles crystal growth transmission electron microscopy in-situ electron microscopy

Legumain-triggered aggregable gold nanoparticles for enhanced intratumoral retention

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Chinese Chemical Letters 2024年第7期35卷 388-393页

作者： Zhi Li Wenpei Li Shaoping Jiang Chuan Hu Yuanyu Huang Maxim Shevtsov Huile Gao Shaobo Ruan Advanced Research Institute of Multidisciplinary sciences School of Life ScienceBeijing Institute of TechnologyBeijing 100081China Key Laboratory of Drug Targeting and Drug Delivery System West China School of PharmacySichuan UniversityChengdu 610041China Institute of Cytology of russian academy of sciences(RAS) St.Petersburg 194064Russia

Insufficient intratumoral retention of nanomedicines remains the major challenge for broad implementation in clinical ***,we proposed a legumain-triggered aggregable gold nanoparticle(GNP)delivery platform(GNPs-A&C).GNPs-A&C could form intratumoral or intracellular aggregates in response to the overexpressed *** aggregates with size increase not only could reduce back-flow from interstitial space to peripheral bloodstream but also could restrict the cellular exocytosis,leading to enhanced intratumoral *** vitro studies demonstrated that GNPs-A&C possessed an excellent legumain responsiveness and the increased size was closely relevant with legumain *** vivo studies demonstrated GNPs-A&C possessed slower clearance rate and much higher intratumoral retention within legumain-overexpressed tumor compared to non-aggregable NPs,regardless of intravenous or intratumoral *** importantly,this delivery platform significantly improved the chemotherapeutic effect of doxorubicin(DOX)towards subcutaneous xenograft C6 *** effectiveness of this stimulus-responsive aggregable delivery system provides a thinking for designing more intelligent size-tunable nanomedicine that can substantially improve intratumoral retention.

关键词： Legumain Size-tunable Enhanced retention Stimulus-responsive Nanomedicine

Interdecadal changes in the western Siberian summer mean and extreme rainfall during 1982-2021

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Atmospheric and Oceanic science Letters 2024年第3期17卷 37-41页

作者： Yali Zhu Fangwu Song Dong Guo Nansen-Zhu International Research centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjingChina Carbon Neutrality Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Earth and Planetary sciences University of Chinese Academy of SciencesBeijingChina

本文研究发现,西西伯利亚夏季降水在1995年后显著增加,2012年后又有所减少,极端降水日数和强度呈现一致的变化特征.伴随这两次降水的年代际增加/减少,西西伯利亚上空出现异常气旋/反气旋和水汽幅合/幅散.极端降水发生时的区域环流特征... 详细信息

本文研究发现,西西伯利亚夏季降水在1995年后显著增加,2012年后又有所减少,极端降水日数和强度呈现一致的变化特征.伴随这两次降水的年代际增加/减少,西西伯利亚上空出现异常气旋/反气旋和水汽幅合/幅散.极端降水发生时的区域环流特征在三个时段基本一致:西西伯利亚低空出现气旋性异常,高空为西北-东南向的异常气旋-反气旋偶极子型.1995-2011年期间,极端降水日数更多,强度更强,上述异常环流型也更强.

关键词：西伯利亚夏季降水年代际变化乌拉尔高压北大西洋波流相互作用

On Differential Equations of Integrable Billiard Tables

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Acta Mathematica Sinica,English Series 2024年第1期40卷 417-424页

作者： Vladimir DRAGOVIC Andrey E.MIRONOV Department of Mathematical sciences The University of Texas at DallasRichardson TXUSA Mathematical Institute SANU BelgradeSerbia Novosibirsk State University NovosibirskRussia Sobolev Institute of Mathematics of the Siberian Branch of the russian academy of sciences NovosibirskRussia

We introduce a method to find differential equations for functions which define tables,such that associated billiard systems admit a local first *** illustrate this method in three situations:the case of(locally)integrable wire billiards,for finding surfaces in R^(3)with a first integral of degree one in velocities,and for finding a piece-wise smooth surface in R^(3)homeomorphic to a torus,being a table of a billiard admitting two additional first integrals.

关键词： Polynomial first integrals wire billiards piece-wise smooth surfaces