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Recent advances in functional utilisation of environmentally friendly and recyclable high-performance green biocomposites: A review

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Chinese Chemical Letters 2024年第4期35卷 73-85页

作者： Guiyang Zheng Xuelian Kang Haoran Ye Wei Fan christian Sonne Su Shiung Lam Rock Keey Liew Changlei Xia Yang Shi Shengbo Ge Co-Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037China School of Textile Science and Engineering&Key Laboratory of Functional Textile Material and Product of Ministry of Education Xi'an Polytechnic UniversityXi'an 710048China Department of Bioscience Arctic Research Centre(ARC)Aarhus UniversityFrederiksborgvej 399PO Box 358DK-4000 RoskildeDenmark Sustainability Cluster School of EngineeringUniversity of Petroleum&Energy StudiesDehradunUttarakhand 248007India Higher Institution Centre of Excellence(HICoE) Institute of Tropical Aquaculture and Fisheries(AKUATROP)Universiti Malaysia Terengganu21030 Kuala NerusTerengganuMalaysia Center for Transdisciplinary Research Saveetha Institute of Medical and Technical SciencesSaveetha UniversityChennai 600072India NV Western PLT Georgetown 10400PenangMalaysia Aerospace Kaitian Environmental Technology Co. Ltd.Changsha 410000China Hunan Hongsen Novel Material Technology Co. Ltd.Yiyang 413407China

Humans have relied on biomass for survival and development since the Stone Age. All aspects of human needs for materials are covered by tools, fuel, and buildings. Nowadays, metals and petroleum-based materials are widely used in highly developed industries. Unfortunately, environmental contamination and the loss of natural resources have led to the reemergence of biomass resources as efficient and sustainable energy sources. Notably, simple and direct applications can no longer meet the demand for functionalization, high performance of materials and construction materials. Therefore, it is imperative to modify biomass and combine its utilisation to produce functionalization and high performance materials. For example, construction materials with superior mechanical properties and water resistance can be produced by reinforcing fibres to facilitate crosslinking. Water-oil separation or adsorption effects of hydrogels and aerogels are determined by the porosity and lightness of biomass, biocomposite conductor is prepared by chimaeric conductive material. Here, we review the approaches that have been taken to devise an environmentally friendly yet fully recyclable and sustainable functionalised biocomposites from biomass and its potential directions for future research.

关键词： Biocomposite Renewable Sustainability Advanced functional material Pollution mitigation

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Prevalence and Associated Factors of Hepatitis B Surface Antigen (HBsAg) among People Living with HIV (PLWHIV) Attending at CTC Mawenzi Regional Hospital kilimanjaro, Northern Tanzania

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Advances in Infectious Diseases 2021年第2期11卷 216-231页

作者： Benedicto Shimula Nyalika kilimanjaro christian medical university college Kilimanjaro Tanzania

Background: Human immunodeficiency virus (HIV) and hepatitis virus (HBV) coinfection are common due to shared modes of transmission between these viruses. Also studies have shown that HIV appears to be a risk factor for reactivation of hepatitis B in patients who have developed hepatitis B surface antibodies HBsAg which is considered as a marker of chronic HBV infection. The magnitude of HIV/HBV coinfection among people living with HIV in Tanzania is not well known. Objective: The aim of this study was to determine the prevalence and associated factors of HBsAg among HIV Positive Clients at CTC at Mawenzi Regional Hospital. Methods: It was a cross sectional study that included 100 HIV Positive CTC clients at Mawenzi Regional Hospital. Ethical clearance was obtained at KCMUCo ethical committee, structured questionnaires with closed-ended question were used to collect the information needed done by interviewing the person, blood sample was collected from median cubital vein and HBsAg Rapid Test Strips were used. Data processing and analysis were done using SPSS version 20. Results: Of 100 HIV patients, only 8 (8%) tested positively for HBsAg. There was a significant association between residence and HBV infection. People from rural areas had high prevalence compared to urban areas (OR 8.71, 95% CI: 1.029 - 73.66). Other social demographic and clinical characteristics in this study had no significant association with HBsAg positivity. Conclusion: Significant numbers of 8% HIV patients are HBsAg positive. HIV patients from rural residency are more likely to acquire HBV than Urban residents that showed significant association.

关键词： HIV HBV HBsAg Care and Treatment Center (CTC)

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Evaluation of Mobile Electronic Devices in Detecting Optic Disc and Visual Field Parameters in Patients with Glaucoma at a Tertiary Hospital in Northeastern Tanzania

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Open Journal of Ophthalmology 2020年第3期10卷 230-238页

作者： Francisco Alcides Mulobuana Tolbert Sonda Martin M. Rwabilimbo William Makupa kilimanjaro christian medical university college Moshi Tanzania kilimanjaro Clinical Research Institute Moshi Tanzania Department of Epidemiology and Applied Biostatistics Kilimanjaro Christian Medical College University Moshi Tanzania kilimanjaro christian medical Centre Moshi Tanzania

Background: Glaucoma is a serious public health problem since it causes visual impairment impacting social, mental and physical health of an individual. Diagnosis and management of glaucoma continue to be a challenge due to few qualified personnel and high cost of the equipment. The use of portable Eye Examination Kit such as Smartphone and tablets can be used in glaucoma screening for taking high-resolution fundus photos for optic disc and visual field parameters, respectively. This study was conducted to evaluate the applicability of mobile electronic device to detect optic disc and visual field parameters for glaucoma in a resource limited setting. Objective: To evaluate the applicability of mobile electronic devices to detect optic disc and visual field parameters for glaucoma. Methodology: Across-sectional study was conducted at KCMC Eye department from October 2018 to June 2019. Study included 140 participants attending eye clinic of which 67 had glaucoma and 73 without glaucoma. Clinical and socio-demographic data were collected using a structured questionnaire and analysed using Stata 15. Glaucoma examination was made on the right eye and photo comparison made between those with and without glaucoma. PEEK Smartphone fundus photo examination was compared with the gold standard machine (Slit Lamp Biomicroscopy), Amsler grid chart installed on a tablet (Microsoft surface, internal storage 256 GB, 2013) and contrast sensitivity compared with Humphrey field analyser (i series, model 740117434, Carl Zeiss Meditec). Results: The kappa (k) agreement between Slit lump biomicroscopy fundus view image and PEEK Smartphone concerning the optic disc measurement was 0.92 with sensitivity and specificity of 90.32% (95% CI: 80.12 - 96.37) and 93.59% (95% CI: 85.67 - 97.89) with a p < 0.001 respectively. An agreement between Amsler grid and Humphrey Field Analyser was 0.67 with sensitivity of 33.33% (95% CI:

关键词： Glaucoma PEEK Smartphone Contrast Sensitivity Amsler Grid kilimanjaro

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Visual Outcome and Predictors of Poor Visual Outcome among Uveitis Patients Attended at KCMC Eye Department, Moshi—Northern Tanzania

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Open Journal of Ophthalmology 2020年第2期10卷 123-132页

作者： Abrahamo Arao Nhutene Matova William Makupa kilimanjaro christian medical university college (KCMUCo) Moshi Tanzania kilimanjaro christian medical Center Hospital Moshi Tanzania

Background: Uveitis, an inflammatory disease of the middle layer of the human eye is a potentially blinding disease, carrying social, economic and individual consequence. Though not being a leading blinding disease, it causes visual impairment and blindness with its complications like cataract and glaucoma. Few studies have addressed the visual outcome after diagnoses and follow-up of patients with uveitis;and at our setting, few is known about the visual outcome, factors predicting poor outcome. Methodology and Materials: This was a hospital-based cohort study conducted at the kilimanjaro christian medical Center (KCMC), Eye Department. Files of patients attended from January 2010 to December 2017 were assessed. Measures of Central Tendency and their corresponding dispersion were used to summarize continuous variables and proportions for categorical variables. One sample paired t-test was used to assess differences in mean Best Corrected Visual Acuity (BCVA) and Wilcoxon Signed Rank test for differences in median BCVA between the first visit and at one year respectively. Association between predictors and poor outcome was analyzed by using Chi square test. Multivariate regression was used to control for potential confounders and a p value less than 0.05 was considered as statistical significant. Results: A total of 291 patients were assessed, majority of them being female (54.6%), with median age being 53 years. The proportion of visual impairment reduced from the initial 57.7% at presentation to 28.2% at one year. The mean BCVA improved from the initial 0.96 log MAR to 0.70 log MAR at one year. The main factors associated with poor presenting vision were: Cataract (p value Conclusions: at one year of follow-up of patients with uveitis, the proportion of visual impairment reduces significantly, with improvement also being observed on mean visual acuity. The most common predictors of poor visual outcome were Cataract, Glaucoma CME, abnormal IOP and Maculopathy.

关键词： Visual Outcomes Predictors Uveitis

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Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection

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Journal of Intensive Medicine 2024年第1期4卷 81-93页

作者： Marie Dejonckheere Massimo Antonelli Kostoula Arvaniti Koen Blot Ben CreaghBrown Dylan Wde Lange Jan De Waele Mieke Deschepper Yalim Dikmen George Dimopoulos christian Eckmann Guy Francois Massimo Girardis Despoina Koulenti Sonia Labeau Jeffrey Lipman Fernando Lipovestky Emilio Maseda Philippe Montravers Adam Mikstacki JoseArtur Paiva Cecilia Pereyra Jordi Rello JeanFrancois Timsit Dirk Vogelaers Stijn Blot the Abdominal Sepsis Study(AbSeS)group on behalf of the Trials Group of the European Society of Intensive Care Medicine Department of Internal Medicine and Pediatrics Faculty of Medicine and Health SciencesGhent UniversityGhentBelgium Department of Anesthesiology Intensive Care and Emergency MedicineFondazione Policlinico Universitario A.Gemelli IRCCSRomeItaly UniversitàCattolica del Sacro Cuore RomeItaly Intensive Care Unit Papageorgiou University Affiliated HospitalThessaloníkiGreece Department of Epidemiology and Public Health SciensanoIxellesBelgium Surrey Perioperative Anaesthetic Critical Care Collaborative Research Group(SPACeR) Royal Surrey County HospitalGuildfordUK Department of Clinical and Experimental Medicine University of SurreyGuildfordUK Department of Intensive Care Medicine University Medical Center UtrechtUniversity UtrechtUtrechtthe Netherlands Department of Intensive Care Medicine Ghent University HospitalGhentBelgium Data Science Institute Ghent University HospitalGhentBelgium Department of Anesthesiology and Reanimation Cerrahpasa School of MedicineIstanbul University-CerrahpasaIstanbulTurkey rd Department of Critical Care “EVGENIDIO”HospitalNational and Kapodistrian University of AthensAthensGreece Department of General Visceral and Thoracic SurgeryKlinikum Hannoversch-MuendenGoettingen UniversityGöttingenGermany Division of Scientific Affairs-Research European Society of Intensive Care MedicineBrusselsBelgium Anesthesia and Intensive Care Department University Hospital of ModenaModenaItaly UQ Centre for Clinical Research Faculty of MedicineThe University of QueenslandBrisbaneQLDAustralia nd Critical Care Department Attikon University HospitalAthensGreece Department of Nursing Faculty of EducationHealth and Social WorkUniversity College GhentGhentBelgium Jamieson Trauma Institute The University of QueenslandBrisbaneQLDAustralia Nimes university Hospital University of MontpellierNimesFrance Critical Care Department Hospital of the Interamerican Open University(UAI)Buenos AiresArgentina Surgical Critical Care Department of AnesthesiaHospital Universitario

Background:The AbSeS-classification defines specific phenotypes of patients with intra-abdominal infection based on the(1)setting of infection onset(community-acquired,early onset,or late-onset hospital-acquired),(2)presence or absence of either localized or diffuse peritonitis,and(3)severity of disease expression(infection,sepsis,or septic shock).This classification system demonstrated reliable risk stratification in intensive care unit(ICU)patients with intra-abdominal *** study aimed to describe the epidemiology of ICU patients with pancreatic infection and assess the relationship between the components of the AbSeS-classification and ***:This was a secondary analysis of an international observational study(“AbSeS”)investigating ICU patients with intra-abdominal *** patients with pancreatic infection were included in this analysis(n=165).Mortality was defined as ICU mortality within 28 days of observation for patients discharged earlier from the *** with mortality were assessed using logistic regression analysis and reported as odds ratio(OR)and 95%confidence interval(CI).Results:The overall mortality was 35.2%(n=58).The independent risk factors for mortality included older age(OR=1.03,95%CI:1.0 to 1.1 P=0.023),localized peritonitis(OR=4.4,95%CI:1.4 to 13.9 P=0.011),and persistent signs of inflammation at day 7(OR=9.5,95%CI:3.8 to 23.9,P<0.001)or after the implementation of additional source control interventions within the first week(OR=4.0,95%CI:1.3 to 12.2,P=0.013).Gramnegative bacteria were most frequently isolated(n=58,49.2%)without clinically relevant differences in microbial etiology between survivors and ***:In pancreatic infection,a challenging source/damage control and ongoing pancreatic inflammation appear to be the strongest contributors to an unfavorable short-term *** this limited series,essentials of the AbSeS-classification,such as the setting of infection onset,diffuse

关键词： Pancreatic infection Intensive care unit Mortality Intra-abdominal infection Sepsis

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Awareness and Factors Associated with Postpartum Modern Contraceptives Use among Women of Reproductive Age in Bukombe District, Geita Region

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Advances in Sexual Medicine 2020年第3期10卷 71-85页

作者： Immanuel Shayo Sia E. Msuya Caroline Amour Michael J. Mahande kilimanjaro christian medical university college Moshi Tanzania Department of Epidemiology & Biostatistics Institute of Public Health Kilimanjaro Christian Medical University College Moshi Tanzania Department of Community Health Institute of Public Health Kilimanjaro Christian Medical Centre Moshi Tanzania

Introduction: Pregnancies that occur during the first year postpartum are more likely to be unplanned. This leads to an increased risk of adverse maternal and perinatal outcomes. However, modern contraceptive use during this period helps to reduce unplanned pregnancies and its associated adverse outcomes. There is scant data on postpartum contraceptives in pastoral communities in Tanzania. This study aimed to assess awareness and factors associated with postpartum modern contraceptives use among women of reproductive age in Bukombe District, Geita Region. Method: A community based cross-sectional study was conducted in a predominant pastoral community of Bukombe district in Geita region in north-western Tanzania from May-June 2018. A total of 511 postpartum women who were in their first year after child birth were studied. A multistage sampling technique was used to select study participants. Data analysis was performed using SPSS version 21. Multivariable logistic regression analysis was used to determine independent predictors of postpartum modern contraceptive use. Results: Most (97.3%) of the participants were aware about modern contraceptives. The prevalence of postpartum modern contraceptive use was 11.9%. The most frequent used contraceptive method was Implant 6.5%. Majority (75%) of women started to use the contraceptive at the first three months after delivery. Living in urban (AOR = 1.84, 95% CI: 1.20 - 3.79), business women’s (AOR = 2.34, 95% CI: 1.31 - 2.28), having last born aged 3 - 4 months (AOR = 3.30, 95% CI: 1.11 - 9.85) and menses resumption (AOR = 9.23, 95% CI: 3.60 - 23.72) were associated with postpartum modern contraceptive use. Fear of side effects, poor knowledge about contraceptives, husband restrictions, distance to health facility and availability of contraceptive were the barriers for use of contraceptive use. Conclusion: We found low uptake of postpartum modern contraceptive use in this population. Numerous f

关键词： Awareness Postpartum Modern Contraceptives Use Tanzania

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Prevalence and Determinants of Modern Contraceptive Methods Use among Women of Reproductive Age (15 - 49 Years) in Rural Setting: A Case of Kishapu District, Shinyanga Region

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Advances in Sexual Medicine 2019年第4期9卷 53-66页

作者： Veronica Martin Sia E. Msuya Ntuli Kapologwe Damian J. Damian Beatrice John Michael J. Mahande Department of Epidemiology and Biostatistics Institute of Public Health Kilimanjaro Christian Medical University College Moshi Tanzania kilimanjaro christian medical Centre Moshi Tanzania Community Health Department Kilimanjaro Christian Medical University College Moshi Tanzania Shinyanga Regional medical Office Shinyanga Tanzania

Background: Modern contraceptive use among women of reproductive age (15 - 49 years) is a public health priority in Tanzania. The national prevalence remains unacceptably low as 32%. Shinyanga region is one among the regions with lowest contraceptive prevalence rate (21%) and high unmet need for family planning (23%). Understanding factors contributing to its use may help to improve maternal and child health. This study aimed to assess the prevalence and determinants of modern contraceptive use among women of reproductive age. Methods: A community-based cross-sectional study was conducted in Kishapu district of Shinyanga region: A total of 602 women aged 15 - 49 years were interviewed using a standardized questionnaire. Data were analysed using SPSS version 20.0. Odds ratios with 95% confidence intervals for factors associated with use of modern contraceptives were estimated in multivariable logistic regression models. Results: The prevalence of modern contraceptive use was 42.7%. Being employed (OR 2.42, 95% CI: 1.13 - 5.18), formal educational level (OR 2.45, 95% CI: 1.38 - 4.35), couples communication (OR 2.44, 95% CI: 1.74 - 3.42) and availability of modern contraceptives (OR 1.94, 95% CI: 1.17 - 3.20) were significantly associated with current use of modern contraceptives. Husband disapproval was frequently reported as barrier for modern contraceptives in the study area. Conclusions: Numerous factors were associated with use of modern contraceptives. Husband disapproval was frequently reported as barrier for contraceptive use. Strategies to promote the importance of modern contraceptives use in the study area are warranted. District health office and concerned stakeholders should encourage male involvement for family planning.

关键词： Family Planning Modern Contraceptive Use Prevalence Determinants

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Rare Case of Surviving Infant with Strawberry Yoghurt like Blood Diagnosed to Be Infantile Hypertriglyceridemia at 1 Month Old: A Case Report

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Open Journal of Pediatrics 2021年第4期11卷 777-785页

作者： Matei Mselle Aisa Shayo Ronald Mbwasi Faith Mosha Jeremia Pyuza Philip Mrindoko Nyemo Peter Elton Meleki Elise Kimambo Arnold Likiliwike Lucy Frisch Magreth Swai Zaituni Hatibu Ally Iman Beatrice Maringo Linda Kissila Ikupa Minga Deborah Mchaile Department of Paediatrics and Child Health Kilimanjaro Christian Medical University College Moshi Tanzania Department of Paediatrics and Child Health Kilimanjaro Christian Medical Centre Moshi Tanzania Department of Clinical Laboratory Kilimanjaro Christian Medical Centre Moshi Tanzania

Background: Hypertriglyceridemia in children means increased plasma fasting Triglyceride levels above the 95th percentile for age and sex. For children aged 0 to 9 years, a triglyceride level greater than or equal to 100 mg/dl is considered above the 95th percentile. Hypertriglyceridemia can be mild to borderline high, moderate to high, very high, severe and very severe (>2000 mg/dl). We present the case of a 1 month and 3 weeks old baby who presented with difficulty in breathing. It was accidentally found to have strawberry yoghurt like blood during phlebotomy, of which upon investigation had very high triglyceride levels of >2000 mg/dl. Case Presentation: 1 month and 3 weeks old female baby, admitted as referral from nearby health centre presenting with difficulty in breath, her blood sample was incidentally found to appear as strawberry yoghurt like. Clinically the infant had features suggestive of respiratory distress, with no other systemic abnormalities noted. Chest X-ray that was don

关键词： Strawberry Yoghurt Like Blood Hypertriglyceridemia Tanzania

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Prevalence and Associated Factors of Dry Eye among Glaucoma Patients at KCMC Eye Department

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Open Journal of Ophthalmology 2020年第2期10卷 154-163页

作者： Mário J. Monjane William Makupa kilimanjaro christian medical university college (KCMUCO) Moshi Tanzania kilimanjaro christian medical Center Hospital Moshi Tanzania Department of Ophthalmology Moshi Tanzania

Propose: Dry eye is a common disease among glaucoma patient undergoing on topical medication for lowering intraocular pressure. In this study we determine the prevalence and risk factors of dry eye among glaucoma patients. Methodology: We conducted a prospective cross-sectional study at kilimanjaro christian medical Center (KCMC), Ophthalmology Department, over a period of 8 months, from October 2018 to June of 2019. Purposive sampling technique was used, and patients with POAG aged 18 years and above were consecutively selected. Socio-demographic and clinical data were collected. The main outcome variable was dry eye. The data were summarized using SPSS version 23 and analyzed using the STATA software version 13. Results: A total of 325 patients were enrolled into the study;56.6% were male and 43.4% were female. The mean age was 66.1 years (SD11.7). We found that the prevalence of dry eye using OSDI questionnaire was 79.7%;among them evaporative dry eye was found in 36.9% and aqueous deficiency in 43.4%;87.1% had abnormal TBUT;abnormal ocular surface staining was found in 64.3%;Schirmer test was abnormal in 43.4% and 36.9% had meibomian gland dysfunction. The severity of dry eyes among those using OSDI questionnaire is: mild 22.1%, moderate 16.0% and severe 61.9%. Factors such as use of two or more medication (AOR = 2.55, 95% CI: 1.89 - 3.36), 2 - 5 years of medication (AOR = 1.52, 95% CI: 1.35 - 1.88) were associated with dry eye in patients with glaucoma at KCMC. Conclusion: Dry eye is highly prevalent in glaucoma patients in our setting, and showed also the high prevalence of signs and symptoms. The use of timolol combined with other medication in our study was shown to be a strong predictor of having dry eye. To be exposed to two or more medication is strongly predictors of having dry eye.

关键词： Dry Eye Glaucoma

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Delayed inflammatory pulmonary syndrome: A distinct clinical entity in the spectrum of inflammatory syndromes in COVID-19 infection?

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世界重症医学杂志 2023年第4期12卷 226-235页

作者： Prithviraj Bose Binila Chacko Ashwin Oliver Arul Leena Robinson Vimala Balamugesh Thangakunam George M Varghese Mohan Jambugulam Audrin Lenin John Victor Peter Department of medical Intensive Care Christian Medical CollegeVellore 632004Tamil NaduIndia Department of Radiodiagnosis Christian Medical CollegeVellore 632004Tamil NaduIndia Department of Pulmonary Medicine Christian Medical CollegeVellore 632004Tamil NaduIndia Department of Infectious Disease Christian Medical CollegeVellore 632004Tamil NaduIndia Department of Medicine Christian Medical CollegeVellore 632004Tamil NaduIndia

BACKGROUND During the second wave of the coronavirus disease 2019(COVID-19)pandemic,a subset of critically ill patients developed delayed respiratory deterioration in the absence of new infection,fluid overload or extra-pulmonary organ *** To describe the clinical and laboratory characteristics,outcomes,and management of these patients,and to contrast this entity with other post COVID-19 immune dysregulation related inflammatory *** This was a retrospective observational study of adult patients admitted to the medical intensive care unit of a 2200-bed university affiliated teaching hospital,between May and August 2021,who fulfilled clearly defined inclusion and exclusion *** was assessed by a change in PaO_(2)/FiO_(2) ratio and levels of inflammatory markers before and after immunomodulation,duration of mechanical ventilation after starting treatment,and survival to *** Five patients developed delayed respiratory deterioration in the absence of new infection,fluid overload or extrapulmonary organ dysfunction at a median interquartile range(IQR)duration of 32(23-35)d after the onset of *** patients had elevated inflammatory markers,required mechanical ventilation for 13(IQR 10-23)d,and responded to glucocorticoids and/or intravenous *** patient died(20%).CONCLUSION This delayed respiratory worsening with elevated inflammatory markers and clinical response to immunomodulation appears to contrast the well described Multisystem Inflammatory Syndrome–Adults by the paucity of extrapulmonary organ *** diagnosis can be considered in patients presenting with delayed respiratory worsening,that is not attributable to cardiac dysfunction,fluid overload or ongoing infections,and associated with an increase in systemic inflammatory markers like C-reactive protein,inteleukin-6 and ferritin.A good response to immunomodulation can be *** delayed inflammatory pulmonary syndrome may re

关键词： COVID-19 ARDS Multisystem Inflammatory Syndrome in Adults Long COVID Organizing pneumonia

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