检索结果-南通市图书馆

Dual-functional poly(2-methyl-2-oxazoline)/poly(2-(dimethylamine)ethyl methacrylate)mixed brushes with switchable protein adsorption and antibacterial properties

引用

Chinese Journal of Chemical Engineering 2024年第2期66卷 19-30页

作者： Kang He Liangyu Zhu Yanmei Wang CAS key laboratory of Soft Matter Chemistry Department of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China

Herein,binary mixed brushes consisting of poly(2-methyl-2-oxazoline)(PMOXA)and poly(2-(dimethylamine)ethyl methacrylate)(PDMAEMA)with different chain lengths were fabricated by successive grafting of NH_(2)-terminated PMOXA and SH-terminated PDMAEMA onto polydopamine-anchored *** mixed-brush coating was characterized by variable-angle spectroscopic ellipsometry,X-ray photoelectron spectroscopy,Fourier transform infrared spectroscopy,zeta potential measurements,water contact angle,and atomic force *** mixed brushes showed tunable surface charge,wettability,and surface roughness,depending on the degree of PDMAEMA swelling under varying pH and ionic strength(Ⅰ).Then the adsorption behaviors of pepsin,bovine serum albumin(BSA),γ-globulin,and lysozyme,four very different proteins with regard to isoelectric point,on the mixed brushes coating were studied by using fluorescence microscopy and surface plasmon *** the chain length of PDMAEMA was about twice as long as PMOXA,the mixed brushes not only had high adsorption capacity for pepsin,BSA,and y-globulin but also had a desorption efficiency of 86.9%,87.1%,and 93.5%,*** is explained that electrostatic attraction between the protonated PDMAEMA and positively charged acidic proteins(pepsin and BSA,whose isoelectric points were below the pK_(a) of PDMAEMA)would drive the intensive adsorption(at pH 3,I=10^(-3)mol·L^(-1)for pepsin,and pH 5,I=10^(-5)mol·L^(-1)for BSA),while desorption was dominated by the hydrophilic PMOXA when PDMAEMA was shrinking(at pH 7,I=10^(-1)mol·L^(-1)for pepsin,and pH 9,I=10^(-1)mol·L^(-1)for BSA).Furthermore,the isoelectric precipitation led to the adsorption of neutral protein(γ-globulin,whose isoelectric point was near the pK_a of PDMAEMA)at pH 7,I=10^(-5)mol·L^(-1),while electrostatic repulsion and antifouling PMOXA triggered the desorption of y-globulin at pH 3,I-10^(-1)mol·L^(-1).However,alkaline protein(lysozyme,whose isoelectric point was higher than

关键词： Switchable conformation transition Controllable protein adsorption Mixed brushes Isoelectric point Antibacterial surface

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Y,Al Co‑Doping on Hydrogen Storage Properties of La–Mg–Ni‑Based Alloys

引用

Acta Metallurgica Sinica(English Letters) 2024年第8期37卷 1399-1410页

作者： Guanjiu Wu Yichao Xie Yuan Li Qing Wang Chenfeng Fan Wenfeng Wang Lu Zhang Shumin Han Hebei key laboratory of Applied Chemistry Yanshan UniversityQinhuangdao 066004China State key laboratory of Metastable Materials science and technology Yanshan UniversityQinhuangdao 066004China

La–Mg–Ni-based hydrogen storage alloys have excellent hydrogen storage *** work reports the hydrogen storage performance of a series of A_(2)B_(7)-type La_(0.96)Mg_(0.04)N_(i3.34)Al_(0.13)alloy and La_(0.96-x)Y_(x)Mg_(0.04)Ni_(3.47–0.6x)Al_(0.6x)(x=0,0.22,0.33,0.44)alloys,and explores the effect of Y and Al element combined substitution on the microstructure and hydrogen storage performance of A_(2)B_(7)-type La–Mg–Ni-based *** alloys are composed of Ce_(2)Ni_(7)phase and LaNi_(5)*** the increase of x,the cell volume of Ce_(2)Ni_(7)phase decreases,while that of LaNi_(5)phase increases,indicating that Y atom mainly enters Ce_(2)Ni_(7)phase and Al atom mainly enters LaNi_(5)*** appropriate amount of co-substitution increases the hydrogen storage capacity and reduces the hydrogen absorption/desorption plateau pressure hysteresis of the *** x=0.44,the hydrogen storage capacity of the alloy is 1.449 wt%,and the hysteresis coefficient is *** cell volume of Ce_(2)Ni_(7)phase and LaNi_(5)phase expands to different degrees after 20 absorption/desorption *** the increase of x,the volume expansion rate decreases,and the cycle capacity retention rate also gradually *** is related to the amorphization of Ce_(2)Ni_(7)*** x=0.22,the capacity retention rate of the alloy is 91.4%.

关键词： La-Mg-Ni-based alloys Gas-phase hydrogen storage performance Ce_(2)Ni_(7)phase LaNi_(5)phase Capacity retention rate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atomic layer deposition in advanced display technologies:from photoluminescence to encapsulation

引用

International Journal of Extreme Manufacturing 2024年第2期6卷 65-82页

作者： Rong Chen Kun Cao Yanwei Wen Fan Yang Jian Wang Xiao Liu Bin Shan State key laboratory of Intelligent Manufacturing Equipment and technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiPeople’s Republic of China State key laboratory of Materials Processing and Die&Mould technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiPeople’s Republic of China

Driven by the growing demand for next-generation displays,the development of advanced luminescent materials with exceptional photoelectric properties is rapidly accelerating,with such materials including quantum dots and phosphors,***,the primary challenge preventing the practical application of these luminescent materials lies in meeting the required durability *** layer deposition(ALD)has,therefore,been employed to stabilize luminescent materials,and as a result,flexible display devices have been fabricated through material modification,surface and interface engineering,encapsulation,cross-scale manufacturing,and *** addition,the appropriate equipment has been developed for both spatial ALD and fluidized ALD to satisfy the low-cost,high-efficiency,and high-reliability manufacturing *** strategic approach establishes the groundwork for the development of ultra-stable luminescent materials,highly efficient light-emitting diodes(LEDs),and thin-film ***,this significantly enhances their potential applicability in LED illumination and backlighted displays,marking a notable advancement in the display industry.

关键词： atomic layer deposition display luminescent encapsulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A gold-based multiplex immunochromatographic sensor for detecting paclitaxel

引用

Nano Research 2024年第7期17卷 6420-6429页

作者： Xiaoqian Jiang Aihua Qu Xinxin Xu Hua Kuang Liqiang Liu Chuanlai Xu State key laboratory of Food science and technology Jiangnan UniversityWuxi 214122China International Joint Research laboratory for Biointerface and Biodetection and School of Food Science and TechnologyJiangnan UniversityWuxi 214122China

Paclitaxel(PTX),methotrexate(MTX),and 5-fluorouracil(5-FU)are commonly-used small molecule anti-tumor drugs for breast ***,drug resistance occurs with long-term treatment or excessive use,and the high concentrations of PTX,MTX,and 5-FU in patients may lead to side effects with dose-limiting toxicities,such as myelosuppression,hepatotoxicity,and peripheral ***,concentration monitoring of PTX,MTX,and 5-FU in clinical treatment is very *** prepared highly sensitive and specific monoclonal antibodies using several haptens,and established a multiple paper-based sensor utilizing optical signals of gold nanoparticles,which simultaneously detected PTX,MTX,and 5-FU in human plasma or urine with 10 min.A portable scanner for quantitative detection in plasma and urine samples was used,and the calculated limit of detection(cLOD)values were 0.002 and 0.142μg/mL for PTX,0.187 and 0.976 ng/mL for MTX,and 0.057 and 0.128μg/mL for 5-FU,*** the recovery test,the recovery rates and the coefficient of variation were 85.84%–108.81%and 1.23%–8.80%,respectively,indicating the reliability and accuracy of the multiple gold immunochromatographic strip(GIS).In addition,for the determination of collected clinical plasma samples,the correlation between the test data of the multiple GIS and liquid chromatography–tandem mass spectrometry(LC–MS/MS)was ***,the developed multiple GIS could be applied to the rapid detection of PTX,MTX,and 5-FU in different clinical samples.

关键词： paclitaxel methotrexate 5-fluorouracil immunochromatographic assay plasma urine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

FPGA-based position reconstruction method for neutron beam flux spatial distribution measurement in BNCT

引用

Nuclear science and Techniques 2024年第3期35卷 96-108页

作者： Wei Jiang Ping Cao Yi-Ming Wu Xian-Ke Liu Zhu-Jun Fang Zhi-Yong Zhang Bin Shi Jun Chen State key laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China School of Nuclear science and technology University of Science and Technology of ChinaHefei 230026China National key laboratory for Metrology and Calibration Techniques China Institute of Atomic EnergyBeijing 102413China

A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas *** address the issue of long processing times in traditional offline position reconstruction methods,this paper proposes a field programmable gate array based online position reconstruction method utilizing the micro-time projection chamber *** method encapsulates key technical aspects:a self-adaptive serial link technique built upon the dynamical adjustment of the delay chain length,fast sorting,a coordinate-matching technique based on the mapping between signal timestamps and random access memory(RAM)addresses,and a precise start point-merging technique utilizing a circular combined *** performance test of the selfadaptive serial link shows that the bit error rate of the link is better than 10-12 at a confidence level of 99%,ensuring reliable data *** experiment utilizing the readout electronics and Micromegas detector shows a spatial resolution of approximately 1.4 mm,surpassing the current method’s resolution level of 5 *** beam experiment confirms that the readout electronics system can obtain the flux spatial distribution of neutron beams online,thus validating the feasibility of the position reconstruction *** online position reconstruction method avoids traditional methods,such as bubble sorting and traversal searching,simplifies the design of the logic firmware,and reduces the time complexity from O(n2)to O(n).This study contributes to the advancement in measuring neutron beam flux for BNCT.

关键词： Position reconstruction FPGA Readout electronics Neutron flux spatial distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Scalable synthesis of lipid nanoparticles for nucleic acid drug delivery using an isometric channel-size enlarging strategy

引用

Nano Research 2024年第4期17卷 2899-2907页

作者： Zesen Ma Haiyang Tong Sijin Lin Li Zhou Demeng Sun Baoqing Li Changlin Tian Jiaru Chu Department of Precision Machinery and Precision Instrumentation University of Science and Technology of ChinaHefei 230027China key laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes University of Science and Technology of ChinaHefei 230027China science Island Branch Graduate SchoolUniversity of Science and Technology of ChinaHefei 230026China Anhui Provincial key laboratory of High Field Magnetic Resonance imaging High Magnetic Field LaboratoryHefei Institute of Physical ScienceChinese Academy of SciencesHefei 230031China Anhui Provincial Engineering laboratory of Peptide Drugs University of Science and Technology of ChinaHefei 230027China School of Biomedical Engineering Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaSuzhou 215127China

Lipid nanoparticles(LNPs)have emerged as highly effective delivery systems for nucleic acid-based ***,the broad clinical translation of LNP-based drugs is hampered by the lack of robust and scalable synthesis techniques that can consistently produce formulations from early development to clinical *** this work,we proposed a method to achieve scalable synthesis of LNPs by scaling inertial microfluidic mixers isometrically in three ***,a theoretical predictive method,which controls the mixing time to be equal across different chips,is developed to ensure consistent particle size and size distribution of the synthesized *** loaded with small interfering RNA(siRNA)were synthesized at different flow rates,exhibiting consistent physical properties,including particle size,size distribution and encapsulation *** work provides a practical approach for scalable synthesis of LNPs consistently,offering the potential to accelerate the transition of nucleic acid drug development into clinical application.

关键词： lipid nanoparticles nucleic acid delivery microfluidics scalable synthesis consistent particle size

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A FAS approach for stabilization of generalized chained forms: part 2. Continuous control laws

引用

science China(Information sciences) 2024年第3期67卷 114-135页

作者： Guang-Ren DUAN Center for Control Theory and Guidance technology Harbin Institute of Technology Shenzhen key laboratory of Control Theory and Intelligent Systems Southern University of Science and Technology

In this paper, continuous time-varying stabilizing controllers for the type of general nonholonomic systems proposed and treated in part 1 are designed using the fully actuated system(FAS) approach. The key step is to differentiate the first scalar equation, and by control of the obtained second-order scalar system, a proportional plus integral feedback form for the first control variable is obtained. With the solution to this designed second-order scalar system, the rest equations in the nonholonomic system form an independent time-varying subsystem which is then handled by the FAS approach. The overall designed controller contains an almost arbitrarily chosen design parameter, and is proven to guarantee the uniformly and globally exponential stability of the closed-loop system. The proposed approach is simple and effective,and is demonstrated with a practical example of ship control.

关键词： nonholonomic systems feedback stabilization fully actuated systems Lyapunov stability continuous controllers

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Large Eddy Simulation of NO Formation in Non-Premixed Turbulent Jet Flames with Flamelet/Progress Variable Approach

引用

Journal of Thermal science 2024年第6期33卷 2399-2412页

作者： WAN Jiawei GUO Junjun WEI Zhengyun JIANG Xudong LIU Zhaohui State key laboratory of Coal Combustion School of Energy and Power EngineeringHuazhong University of Science and Technology (HUST) CCRC King Abdullah University of Science and Technology (KAUST)

To improve the NO modelling in turbulent flames,the flamelet/progress variable(FPV) model is extended by introducing NO mass fraction into the progress variable and incorporating an additional NO transport *** sets of flamelet databases are tabulated with progress variables based on major species and NO mass fraction,*** former is used for the acquisition of the main thermochemical variables,while the latter is employed for NO ***,an additional transport equation is solved to obtain the NO mass fraction,with the source term corrected using the scale similarity *** assessments are first conducted on laminar counterflow diffusion flames to identify lookup-related errors and assess the suitability of progress variable *** results show that the progress variables based on major species and NO could correctly describe the main thermochemical quantities and NO-related variables,***,the model is applied to the large eddy simulation(LES) of Sandia *** results indicate that the extended FPV model improves the NO prediction,with a mean error for NO prediction at 55%,significantly lower than those of existing FPV models(130% and 385%).The LES with the extended FPV model quantitatively captures NO suppression in the mid-range of Reynolds numbers from 22 400(Flame D) to 33 600(Flame E),but underestimates the NO suppression at higher Reynolds numbers from 33 600 to 44 800(Flame F).This underprediction is primarily attributed to the underestimation of local extinction levels in flames with high Reynolds numbers.

关键词： flamelet/progress variable model large eddy simulation NO emission Sandia flames

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

A new quantum key distribution resource allocation and routing optimization scheme

引用

Chinese Physics B 2024年第3期33卷 244-259页

作者：毕琳袁晓同吴炜杰林升熙 School of Computer science and technology Changchun University of Science and TechnologyChangchun 130012China key laboratory of Network and Information Security in Jilin Province Changchun 130012China

Quantum key distribution(QKD)is a technology that can resist the threat of quantum computers to existing conventional cryptographic ***,due to the stringent requirements of the quantum key generation environment,the generated quantum keys are considered valuable,and the slow key generation rate conflicts with the high-speed data transmission in traditional optical *** this paper,for the QKD network with a trusted relay,which is mainly based on point-to-point quantum keys and has complex changes in network resources,we aim to allocate resources reasonably for data packet ***,we formulate a linear programming constraint model for the key resource allocation(KRA)problem based on the time-slot ***,we propose a new scheduling scheme based on the graded key security requirements(GKSR)and a new micro-log key storage algorithm for effective storage and management of key ***,we propose a key resource consumption(KRC)routing optimization algorithm to properly allocate time slots,routes,and key *** results show that the proposed scheme significantly improves the key distribution success rate and key resource utilization rate,among others.

关键词： quantum key distribution(QKD) resource allocation key storage routing algorithm

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Experimental Proposal on Non-Hermitian Skin Effect by Two-dimensional Quantum Walk with a Single Trapped Ion

引用

Chinese Physics Letters 2024年第4期41卷 19-24页

作者：侯琬儿唐皓许勤林毅恒 CAS key laboratory of Microscale Magnetic Resonance and School of Physical sciences University of Science and Technology of ChinaHefei 230026China Hefei National laboratory University of Science and Technology of ChinaHefei 230088China

Non-Hermitian Hamiltonians are widely used in describing open systems with gain and loss,among which a key phenomenon is the non-Hermitian skin *** we report an experimental scheme to realize a twodimensional(2D)discrete-time quantum walk with non-Hermitian skin effect in a single trapped *** is shown that the coin and 2D walker states can be labeled in the spin of the ion and the coherent-state lattice of the ion motion,*** numerically observe a directional bulk flow,whose orientations are controlled by dissipative parameters,showing the emergence of the non-Hermitian skin *** then discuss an experimental implementation of our scheme in a laser-controlled trapped Ca^(+)*** experimental proposal may be applicable to research of dissipative quantum walk systems and may be able to generalize to other platforms,such as superconducting circuits and atoms in cavity.

关键词： effect dissipative quantum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：