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Prevotella and succinate treatments altered gut microbiota,increased laying performance,and suppressed hepatic lipid accumulation in laying hens

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Journal of Animal Science and Biotechnology 2024年第2期15卷 844-861页

作者： Min Liu Zeyue Kang Xikang Cao Hongchao Jiao Xiaojuan Wang Jingpeng Zhao Hai Lin College of Animal Science and Technology Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and PreventionKey Laboratory of Efficient Utilization of Non‑Grain Feed Resources(Co‑Construction by Ministry and Province)Ministry of Agriculture and Rural AffairsShandong Agricultural UniversityTai’an 271018China

Background This work aimed to investigate the potential benefits of administering Prevotella and its primary metabolite succinate on performance,hepatic lipid accumulation and gut microbiota in laying *** One hundred and fifty 58-week-old Hyline Brown laying hens,with laying rate below 80%and plasma triglyceride(TG)exceeding 5 mmol/L,were used in this *** hens were randomly allocated into 5 groups and subjected to one of the following treatments:fed with a basal diet(negative control,NC),oral gavage of 3 mL/hen saline every other day(positive control,PC),gavage of 3 mL/hen Prevotella melaninogenica(10^(7)CFU/mL,PM)or 3 mL/hen Prevotella copri(10^(7)CFU/mL,***)every other day,and basal diet supplemented with 0.25%sodium succinate(Succinate).The results showed that PM and *** treatments significantly improved laying rate compared to the PC(P0.05).PM treatment increased(P<0.05)the mRNA levels of genes PGC-1βand APB-5B at week 4,and ACC and CPT-1 at week *** results indicated enhanced antioxidant activities at week 8,as evidenced by reduced hepatic malondialdehyde(MDA)level and improved antioxidant enzymes activities in PM and Succinate groups(P<0.05).Supplementing with Prevotella or succinate can alter the cecal ***,the abundance of Prevotella in the Succinate group was significantly higher than that in the other 4 groups at the family and genus levels(P<0.05).Conclusions Oral intake of Prevotella and dietary supplementation of succinate can ameliorate lipid metabolism of laying *** beneficial effect of Prevotella is consistent across different *** finding highlights that succinate,the primary metaboli

关键词： Fatty liver Gut microbiota Laying hen Prevotella Succinate

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Dietary Macleaya cordata extract supplementation improves the growth performance and gut health of broiler chickens with necrotic enteritis

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Journal of Animal Science and Biotechnology 2024年第1期15卷 374-395页

作者： Bochen Song Jie He Xue Pan Linglian Kong Chuanpi Xiao Chake Keerqin Zhigang Song key laboratory of efficient utilization of Non‑Grain feed resources College of Animal Science and TechnologyShandong Agricultural UniversityTaian 271018ShandongChina Center for Mitochondria and Healthy Ageing College of Life SciencesYantai UniversityYantai 264005ShandongChina Precision Livestock and Nutrition Unit University of LiègeGembloux Agro‑Bio TechGemblouxBelgium Phytobiotics(Jiangsu)Biotech Co. Ltd.Jintan 213200China

Background The poultry industry needs effective antibiotic alternatives to control outbreaks of necrotic enteritis(NE)caused by Clostridium *** The aim of this study was to investigate the effects of dietary supplementation with Macleaya cordata extract(MCE)on the immune function and gut microbiota of broilers with NE.A total of 2881-day-old broiler chicks were randomly assigned to a 2×2 factorial arrangement with two concentrations of dietary MCE supplementation(0 or 350 mg/kg of diet)and two disease challenge statuses(control or NE).Results The results revealed that NE significantly increased the feed conversion rate(FCR),mortality,intestinal lesion score,the levels of IL-1β,IL-17 and IFN-γ/IL-4 in serum and IL-17/IL-10 in the jejunal mucosa,m RNA levels of TLR2,IFN-γand p Ig R in the jejunum,and Clostridium perfringens concentrations in the *** significantly decreased the body weight(BW),body weight gain(BWG),jejunal villus height,V/C,m RNA level of AMPK-α1 in jejunum,IL-4 level in the jejunal mucosa and lactic acid bacteria abundance in the *** significantly increased BW,BWG,jejunal villus height,V/C,m RNA levels of occludin,ZO-1 and AMPK-α1 in the jejunum,the levels of Ig A and Ig G in serum and IL-10 in the jejunal mucosa and m RNA levels of NF-κB,IL-10 and MHC-II in the ***,MCE significantly decreased the FCR,mortality,intestinal lesion score,jejunal crypt depth,the levels of IFN-γand IL-17 in serum and IL-17/IL-10 in the jejunal mucosa,Clostridium perfringens concentrations in the cecum,and m RNA levels of IL-17/IL-10 in the ***,NE significantly increased the abundance of bacteria that are associated with inflammation,obesity and depression(Alistipes,Barnesiella,Intestinimonas,RF39 and UCG-005)and significantly decreased the abundance of short-chain fatty acid(SCFA)-producing bacteria(Anaerotruncus,Butyricicoccus and Bacteroides)in the *** significantly increased the abundance of SCFA-producing b

关键词： Broiler chicken Gut microbiota Immune function Macleaya cordata extract Necrotic enteritis

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Loading capacity and emulsification phenomena of HREE extraction by dialkylphosphinic acids with different β,γ,δ-substituents

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Journal of Rare Earths 2024年第1期42卷 191-199,I0007页

作者： Junlian Wang Guodong Xu Wen Xu Jianguo Cui Yufu Chen Ziyong Chang School of Civil and Resource Engineering University of Science and Technology BeijingBeijing100083China key laboratory of Ministry of Education for efficient Mining and Safety of Metal Mines Beijing100083China State key laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive utilization Baotou Research Institute of Rare EarthsBaotou014030China

The relationship between dialkylphosphinic acid structure and their loading capacity for HREEs and emulsification phenomena has rarely been *** this paper,we took Lu extraction as an example to study the effect of β,γ,δ-substituents of dialkylphosphinic acids on their loading capacity and anti-emulsification performance for *** discuss conveniently,the dialkylphosphinic acids were classified into two groups:β-substituent group(P208,INET-1,P218,USTB-1 and P227)and γ,δ-substituent group(P218,P2132 and Cyanex 272).For β-substituent group extractants,their loading capacities are in the order P208(299.7 mg/L)≈INET-1(299.5 mg/L)>P218(270.8 mg/L)>>USTB-1(163.1 mg/L)>P227(151.4 mg/L),while their anti-emulsification/gelation performances are just in the opposite order P227>USTB-1>P218>P208≈INET-1 under the studied *** γ,δ-substituent group extractants,their loading capacities are in the order P218(270.8 mg/L)>P2132(192.3 mg/L)>Cyanex272(131.7 mg/L),while the anti-emulsification performance of P218 is better than those of P2132 and Cyanex *** loading capacity data given in the parentheses are obtained through repeatedly extracting Lu from ~4×10^(-4)mol/L of Lu aqueous feed solution with initial pH of 2.40 by 0.01 mol/L extractant at phase ratio A/O of 1:1.

关键词： Heavy rare earth element Dialkylphosphinic acid Extraction Loading capacity Emulsification

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Enhancing Green Ammonia Electrosynthesis Through Tuning Sn Vacancies in Sn‑Based MXene/ MAX Hybrids

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Nano-Micro Letters 2024年第5期16卷 154-168页

作者： Xinyu Dai Zhen‑Yi Du Ying Sun Ping Chen Xiaoguang Duan Junjun Zhang Hui Li Yang Fu Baohua Jia Lei Zhang Wenhui Fang Jieshan Qiu Tianyi Ma key laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials of Liaoning Province College of ChemistryInstitute of Clean Energy ChemistryLiaoning UniversityShenyang 110036People’s Republic of China State key laboratory of Clean and efficient Coal utilization Taiyuan University of TechnologyTaiyuan 030024People’s Republic of China School of Chemistry and Chemical Engineering Anhui UniversityHefei 230601People’s Republic of China School of Chemical Engineering The University of AdelaideAdelaideSA 5005Australia State key laboratory of High‑Efficiency utilization of Coal and Green Chemical Engineering College of Chemistry and Chemical EngineeringNingxia UniversityYinchuan 750021NingxiaPeople’s Republic of China School of Science RMIT UniversityMelbourneVIC 3000Australia Guangdong Provincial key laboratory of Advanced Energy Storage Materials School of Chemistry and Chemical EngineeringSouth China University of TechnologyGuangzhou 510640People’s Republic of China College of Chemical Engineering State Key Laboratory of Chemical Resource EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Renewable energy driven N_(2) electroreduction with air as nitrogen source holds great promise for realizing scalable green ammonia ***,relevant out-lab research is still in its ***,a novel Sn-based MXene/MAX hybrid with abundant Sn vacancies,Sn@Ti_(2)CTX/Ti_(2)SnC–V,was synthesized by controlled etching Sn@Ti_(2)SnC MAX phase and demonstrated as an efficient electrocatalyst for electrocatalytic N2 *** to the synergistic effect of MXene/MAX heterostructure,the existence of Sn vacancies and the highly dispersed Sn active sites,the obtained Sn@Ti2CTX/Ti_(2)SnC–V exhibits an optimal NH_(3) yield of 28.4μg h^(−1) mg_(cat)^(−1) with an excellent FE of 15.57% at−0.4 V versus reversible hydrogen electrode in 0.1 M Na_(2)SO_(4),as well as an ultra-long ***,this catalyst represents a satisfactory NH3 yield rate of 10.53μg h^(−1) mg^(−1) in the home-made simulation device,where commercial electrochemical photovoltaic cell was employed as power source,air and ultrapure water as feed *** as-proposed strategy represents great potential toward ammonia production in terms of financial cost according to the systematic technical economic *** work is of significance for large-scale green ammonia production.

关键词： Green ammonia synthesis N2 electroreduction Renewable energy Sn MXene/MAX hybrid

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Effect of Air Distribution on the Transport Characteristics of Solid Particles in the Thermal Storage and Release System of Circulating Fluidized Bed

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Journal of Thermal Science 2024年第4期33卷 1554-1563页

作者： JI Zengcai SONG Guoliang TANG Zihua SUN Liwei State key laboratory of Coal Conversion Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China Dalian National laboratory for Clean Energy Dalian116023China

Solid particle heat storage technology offers a potential solution to the challenges posed by the significant growth of renewable energy sources,particularly in terms of grid security and ***,it has the capability to optimize the energy utilization efficiency of the power *** order to investigate the transport regulation characteristics of solid particles in the thermal storage and release system of a circulating fluidized bed(CFB),a test rig with a capacity of 0.1 MW(th)was *** rig was utilized to systematically study the transport regulation characteristics of solid particles under the double U-type valve feed structure and U-type valve discharge *** experimental findings indicate that the system's design enables efficient and rapid storage and release of solid particles in the *** air distribution mode,specifically the double U-type valve feed structure and the U-type valve discharge structure,significantly influence the feed and discharge characteristics of the ash storage *** was observed that the impact of loose air on these characteristics is more substantial than that of the return air,irrespective of the feed structure or the return *** adjusting the feed and discharge rate,it is recommended to adopt a scheme that involves coarse adjustment through loose air and fine adjustment through return air.

关键词： solid particle thermal storage air distribution mode transport regulation

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Damage on intestinal barrier function and microbial detoxification of deoxynivalenol:A review

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Journal of Integrative Agriculture 2024年第8期23卷 2507-2524页

作者： Jia Chen Xinran Zhang Ziqi He Dongwei Xiong Miao Long key laboratory of Livestock Infectious Diseases Ministry of Education/College of Animal Science and Veterinary Medicine ShenyangAgricultural UniversityShenyang 110866China

Deoxynivalenol(DON)is a mycotoxin that is produced by various species of Fusarium and is ubiquitous in food and *** low concentrations,it can cause metabolic disorders in animals and humans and,at high concentrations,it can lead to pathological changes in the *** impact of DON on human/animal health and animal productivity has thus attracted a great deal of attention around the *** causes severe damage to the intestine,including compromised intestinal barrier,mucosal damage,weakened immune function,and alterations in gut microbiota *** effects exacerbate intestinal infections and inflammation in livestock and poultry,posing adverse effects on overall ***,research into biological methods for DON detoxification is a crucial avenue for future *** includes the utilization of adsorption,enzymatic degradation,and other biological approaches to mitigate DON's impact,offering new strategies for prevention and treatment of DON-induced *** research will focus on identifying highly efficient detoxifying microorganisms or enzymes to reduce DON levels in food and feed,thereby mitigating its risks to both animals and human health.

关键词： deoxynivalenol(DON) intestinal barrier function mucus barrier immune function flora composition biological detoxification

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Glycerol monolaurate improves intestinal morphology and antioxidant status by suppressing inflammatory responses and nuclear factor kappa-B signaling in lipopolysaccharide-exposed chicken embryos

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Animal Nutrition 2023年第4期15卷 297-306页

作者： Linglian Kong Yuanli Cai Xue Pan Chuanpi Xiao Zhigang Song key laboratory of efficient utilization of nongrain feed resources College of Animal Science and TechnologyShandong Agricultural UniversityTai'anShandong 271018China College of Life Science Qilu Normal UniversityJinanShandong 250200China Precision Livestock and Nutrition Unit Gembloux Agro-Bio TechUniversity of LiegeGembloux 5030Belgium

Medium-chain fatty acids and their derivatives are natural ingredients that support immunological functions in *** effects of glycerol monolaurate(GML)on intestinal innate immunity and associated molecular mechanisms were investigated using a chicken embryo ***-four Arbor Acres broiler embryos were randomly allocated into four *** embryonic day 17.5,the broiler embryos were administered with 9 mg of GML,which was followed by a 12-h incubation period and a12-h challenge with 32μg of lipopolysaccharide(LPS).On embryonic day 18.5,the jejunum and ileum were *** indicated that GML reversed the LPS-induced decline in villus height and upregulated the expression of mucin 2(P<0.05).GML decreased LPS-induced malondialdehyde production and boosted antioxidant enzyme activity(P<0.05).GML alleviated LPS-stimulated intestinal secretion of interleukin(IL)-1β,IL-6,and tumor necrosis factor-a(TNF-a)(P<0.05).GML also normalized LPS-induced changes in the gene expression of Toll-like receptor 4,nuclear factor kappa-B p65(NF-κB p65),cyclooxygenase-2,NOD-like receptor protein 3,IL-18,zonula occludens 1,and occludin(P<0.05).GML enhanced as well the expression of AMP-activated protein kinase a1 and claudin 1(P<0.05).In conclusion,GML improved intestinal morphology and antioxidant status by alleviating inflammatory responses and modulating NF-κB signaling in LPS-challenged broiler embryos.

关键词： Glycerol monolaurate Innate immunity Lipopolysaccharide Nuclear factor kappa-B Chicken embryo

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Motion characteristics and density separation of fine coal in an inflatable-inclined liquid-solid fluidized bed

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Particuology 2021年第5期19卷 299-307页

作者： Bo Lv Bobing Dong Xiaowei Deng Chaojun Fang College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo 454000China Henan key laboratory for Green and efficient Mining&Comprehensive utilization of Mineral resources Henan Polytechnic UniversityJiaozuo 454000China Collaborative Innovation Center of Coal Work Safety and Clean High Efficiency utilization Henan Polytechnic UniversityJiaozuo 454000China

To improve the adaptability of fluidized beds for fine coal separation,a new type of liquid-solid fluidized bed was constructed,i.e.,the inflatable-inclined liquid-solid fluidized bed(IILSFB).A combination of simulation analysis and separation experiments was used to analyze the fluidization characteristics and separation performance of the *** results showed that there was upflow and downflow in the fluidized *** upflow was mainly composed of water flow,followed by light and heavy particles;on the other hand,the downflow was caused by the backflow of heavy particles that settled at the inclined *** addition,the light particles that settled at the inclined section could return to the rising water flow under the action of secondary *** the water velocity,separation time,and secondary gas velocity increased,the comprehensive separation efficiency of fine coal in the fluidized bed improved,while the value decreased as the feed quantity *** also indicated the order of importance for these four factors,i.e.,water velocity,separation time,feed quantity,and secondary gas velocity,on ***,the comprehensive separation efficiency of 0.1-1 mm fine coal varied significantly with various factors,while that of∼0.1 mm and 1-3 mm fine coal was always at a low *** the latter case,the classification process of the size fraction was significantly better than the separation process in the fluidized *** optimal working conditions,an IILSFB was used to separate the fine coal(0.1-1 mm).The yield of clean coal was 37.95% with an ash content of 12.11%,and the possible error was 0.085 g/cm^(3),indicating that the IILSFB had good separation performance for 0.1-1 mm fine coal.

关键词： Inflatable-inclined liquid-solid fluidized bed Fine coal separation Fluidization Separation efficiency Secondary gas velocity Size fraction

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Nitrogen rejection from low quality natural gas by pressure swing adsorption experiments and simulation using dynamic adsorption isotherms

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Chinese Journal of Chemical Engineering 2022年第2期35卷 120-129页

作者： Xinran Zhang Hua Shang Jiangfeng Yang Libo Li Jinping Li Research Institute of Special Chemicals College of Chemistry and Chemical EngineeringTaiyuan University of TechnologyTaiyuan 030024China Shanxi key laboratory of Gas Energy efficient and Clean utilization Taiyuan 030024China

In order to remove N_(2) from low quality natural gas,a mathematical model has been established by Aspen adsorption,using the CH_(4)-selective sorbent silicalite-1 *** dynamic adsorption isotherm was first simulated by breakthrough simulation of a CH_(4)/N_(2) mixture at different adsorption pressures and feed flow rates based on breakthrough *** resulting simulated CH_(4) dynamic adsorption amounts were very close to the experimental data at three different adsorption pressures(100,200,and 300 kPa).Moreover,a single-bed,three-step pressure swing adsorption(PSA)experiment was performed,and the results were in good agreement with the simulated data,further corroborating the accuracy of the gas dynamic adsorption isotherm obtained by the simulation ***,based on the simulated dynamic adsorption isotherm of CH_(4) and N_(2),a four-bed,eight-step PSA process has been designed,which enriched 75%(vol)CH_(4) and 80%(vol)CH_(4) to 95%(vol)and 99%(vol),and provided 99%(vol)recovery.

关键词： Natural gas Silicalite-1 Simulation Dynamic adsorption Pressure swing adsorption process

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Effects of catechins on litter size,reproductive performance and antioxidative status in gestating sows

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Animal Nutrition 2015年第4期1卷 271-275页

作者： Zhiyong Fan Yong Xiao Yonghui Chen Xin Wu Guanglei Zhang Qinhua Wang Chunyan Xie Engineering Research Center for feed Safety and efficient utilization of Ministry of Education Institute of Animal Nutrition Hunan Agricultural University Institute of Subtropical Agriculture Chinese Academy of Sciences

This study was conducted to investigate the effects of catechins on reproductive performance, antioxidative capacity and immune function of gestating sows. A total of 60 cross-bred（Landrace × Large White） multiparious sows were blocked by body weight, parity and backfact and randomly allocated to 1 of 5 treatments: 0.100,200,300, or 400 mg/kg catechins. Dietary treatments were imposed from mating to d 40 of gestation of sows. At farrowing, litter total born, born alive, dead, and normal-（healthy piglets,>0.85 kg） and low-birth weight piglets（ 0.05）. Sows received 200 mg catechin per kg diets showed a reduction（P < 0.05） of the serum MDA level at farrowing compared with all other treatments. Sows received all the levels of catechin showed a reduction（P < 0.05） of serum H2 O2 level compared with sows received the control diet on both d 40 of gestation and farrowing. Our results demonstrated that the catechins may be a potential antioxidant to increase the reproductive performance and antioxidative capacity of sows

关键词： Antioxidative capacity Catechins Gestating sows Litter size Reproductive performance

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