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Navigating the intersection of psychiatry and ophthalmology:A comprehensive review of depression and anxiety management in glaucoma patients

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World Journal of Psychiatry 2024年第3期14卷 362-369页

作者： Prasanna Venkatesh Ramesh Arvind Kumar Morya Ashik Azad Pavithra Pannerselvam Aji Kunnath Devadas Sai Thaejesvi Gopalakrishnan Shruthy Vaishali Ramesh Ajanya K Aradhya Department of Glaucoma and research Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Optometry and Visual Science Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia junior Resident Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Department of Cataract and Refractive Surgery Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia

Glaucoma,a prevalent and debilitating eye disease,has long been associated with vision impairment and ***,recent research has shed light on the often-underestimated psychological dimensions of this *** and depression,two pervasive psychiatric comorbidities,have been increasingly recognized among glaucoma *** comprehensive review aims to explore the intricate relationship between psychiatry and ophthalmology,in the context of managing depression and anxiety in glaucoma *** meticulously examining peer-reviewed literature,we synthesize current knowledge on the prevalence,risk factors,and underlying mechanisms of anxiety and depression in *** evidence reveals that glaucoma patients face an elevated risk of experiencing these mood *** such as progressive vision loss,complex medication regimens,and the fear of further visual deterioration contribute to their ***,we delve into the bidirectional relationship between glaucoma and mood disorders,shedding light on the complex interplay between ocular and emotional *** review investigates the implications of anxiety and depression on glaucoma management,including their potential impact on treatment adherence,disease progression,and overall quality of *** also explore the neurobiological pathways linking glaucoma and mood disorders,providing a foundation for future research and potential therapeutic *** conclusion,recognizing the psychological burden carried by glaucoma patients is essential for holistic and patient-centered *** review underscores the pressing need for integrated approaches that bring together ophthalmological and psychiatric expertise to optimize the well-being of individuals facing the challenges of *** addressing anxiety and depression in glaucoma care,healthcare providers can enhance the overall quality of life for these patients,ultimately leading to improved outcomes and a brighter

关键词： Glaucoma Psychiatry Depression Anxiety Risk factors Bidirectional relationship

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Uncovering the dominant contribution of intermediate volatility compounds in secondary organic aerosol formation from biomass-burning emissions

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National Science Review 2024年第3期11卷 150-158页

作者： Kun Li Jun Zhang David M.Bell Tiantian Wang Houssni Lamkaddam Tianqu Cui Lu Qi Mihnea Surdu Dongyu Wang Lin Du Imad El Haddad Jay G.Slowik Andre S.H.Prevot Environment research Institute Shandong University Laboratory of Atmospheric Chemistry Paul Scherrer Institute

Organic vapors from biomass burning are a major source of secondary organic aerosols(SOAs). Previous smog chamber studies found that the SOA contributors in biomass-burning emissions are mainly volatile organic compounds(VOCs). While intermediate volatility organic compounds(IVOCs) are efficient SOA precursors and contribute a considerable fraction of biomass-burning emissions, their contribution to SOA formation has not been directly observed. Here, by deploying a newly-developed oxidation flow reactor to study SOA formation from wood burning, we find that IVOCs can contribute ～70% of the formed SOA, i.e.>2 times more than VOCs. This previously missing SOA fraction is interpreted to be due to the high wall losses of semi-volatile oxidation products of IVOCs in smog chambers. The finding in this study reveals that SOA production from biomass burning is much higher than previously thought, and highlights the urgent need for more research on the IVOCs from biomass burning and potentially other emission sources.

关键词： atmospheric chemistry biomass burning secondary organic aerosol intermediate volatility organic compounds

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Muse Turned ＂Femme Fatale＂ in D. G. Rossetti＇s Painting and Poetry

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Journal of Literature and Art Studies 2013年第12期3卷 772-786页

作者： Pritha Kundu junior research fellow Calcutta India

In many of D. G. Rossetti＇s paintings, Elizabeth Siddal appears as a model. In real life, they formed a married couple, and the relatonship was not as idealistic as it might have been, between a muse-figure and an artist. After Elizabeth＇s death, Rossetti seemed to have been preoccupied with the ＂Lilith＂ theme in his painting and poetry and somehow he could not free himself from the haunting memory of the ＂wronged wife＂, the muse. This often found manifestation in his portrayal of the ＂femme fatale＂ images. Applying psychoanalysis to art-criticism and literary appreciation, this paper is an attempt to explore the relationship between a model and an artist, which both psychologically and aesthetically, seemed to be working beyond the former＇s death. Through a detailed analysis of the ＂Lilith＂ image in D. G. Rossetti＇s art, this paper has shown the coplexities of the artist＇s agony and anxiety over the image of a muse, a homely beloved--turned into a threatening ＂femme fatale＂, now distant, unknown, frightening yet fascinating, and mystified by death.

关键词： D. G. Rossetti "Lady Lilith" Elizabeth Siddal femme fatale pre-Raphaelite art

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Loss of the accessory chromosome converts a pathogenic tree-root fungus into a mutualistic endophyte

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Plant Communications 2024年第1期5卷 164-180页

作者： Huanshen Wei Zhenhui Zhong Zhongfeng Li Yuwei Zhang Eva H.Stukenbrock Boping Tang Ningning Yang Riccardo Baroncelli Long Peng Zhuo Liu Xinghua He Yuzhan Yang Zhilin Yuan State Key Laboratory of Tree Genetics and Breeding Chinese Academy of ForestryBeijing 100091China research Institute of Subtropical Forestry Chinese Academy of ForestryHangzhou 311400China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Fujian Agriculture and Forestry UniversityFuzhou 350002China Environmental Genomics Christian-Albrechts University24118 KielGermany Max Planck fellow Group Environmental Genomics Max Planck Institute for Evolutionary Biology24306 PlonGermany Jiangsu Key Laboratory for Bioresources of Saline Soils School of WetlandsYancheng Teachers UniversityYancheng 224002China Department of Agricultural and Food Sciences(DISTAL) University of Bologna40127 BolognaItaly

Some fungal accessory chromosomes(ACs)may contribute to virulence in ***,the mecha-nisms by which ACs determine specific traits associated with lifestyle transitions along a symbiotic contin-uum are not *** we delineated the genetic divergence in two sympatric but considerably variable isolates(16B and 16W)of the poplar-associated fungus Stagonosporopsis *** identified a-0.6-Mb horizontally acquired AC in 16W that resulted in a mildly parasitic lifestyle in *** deletion of the AC(D16W)significantly altered the fungal ***,D16W was morphologically more similar to 16B,showed enhanced melanization,and established beneficial interactions with poplar plants,thereby acting as a dark septate *** sequencing(RNA-seq)analysis showed that AC loss induced the upregulation of genes related to root colonization and biosynthesis of indole acetic acid and *** observed that the AC maintained a more open status of chromatin across the genome,indicating an impressive remodeling of cis-regulatory elements upon AC loss,which potentially enhanced symbiotic *** demonstrated that the symbiotic capacities were non-host-specific through comparable experiments on Triticum–and Arabidopsis–fungus ***,the three isolates generated symbiotic interactions with a nonvascular *** summary,our study suggests that the AC is a suppressor of symbiosis and provides insights into the underlying mechanisms of mutualism with vascular plants in the absence of traits encoded by the *** speculate that AC-situ-ated effectors and other potential secreted molecules may have evolved to specifically target vascular plants and promote mild virulence.

关键词： dark septate endophytes effectors lifestyle transition root–fungus symbioses

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Preliminary Deformation Experiment of Ringwoodite at 20 GPa and 1 700 K Using a D-DIA Apparatus

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Journal of Earth Science 2010年第5期21卷 517-522页

作者： Takaaki Kawazoe Tomohiro Ohuchi Norimasa Nishiyama Yu Nishihara Tetsuo Irifune Geodynamics research Center Ehime University Senior research fellow Center Ehime University

A deformation experiment of ringwoodite with a strain of 9% was achieved at 20 GPa and 1 700 K and at a strain rate of 3×10^-5 s^-1 using a deformation-DIA （D-DIA） apparatus and a multi-anvil 6-6 （MA 6-6） assembly. The crystallographic orientations of the deformed sample were successfully analyzed by the electron backscatter diffraction （EBSD） method, although any notable latticepreferred orientation （LPO） was not observed presumably due to the insufficient strain in the present experiment. In this study, the deformation experiment on ringwoodite succeeded at P-T conditions consistent with the lower part of the mantle transition zone and at a controlled strain rate for the first time. The present study extended the pressure range of deformation experiments in the D-DIA apparatus from 16 GPa in our earlier study to 20 GPa at 1 700 K. The successful extension of the pressure range demonstrates potential importance of the D-DIA apparatus in studying rheological properties of minerals under the P-T conditions of the whole mantle transition zone.

关键词： ringwoodite mantle transition zone rheology viscosity mantle dynamics.

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Velocity Profiles between Two Baffles in a Shell and Tube Heat Exchanger

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Journal of Thermal Science 2015年第4期24卷 356-363页

作者： Tae-Hyun Chang Chang-Hoan Lee Hae-Soo Lee Kwon-Soo Lee Senior research fellow of RESEAT Korea Institute of Science and Technology Information Korea Institute of Science and Technology Information Postdoctoral research fellow School of Mechanical Engineering of Kyungnam University International University of Korea

Heat exchangers are extensively utilized for waste heat recovery,oil refining,chemical processing,and steam *** this study,velocity profiles are measured using a 3D particle image velocimetry(PIV)system between two baffles in a shell and tube heat exchanger for parallel and counter *** PIV and computational fluid dynamics results show the occurrence of some strong vectors near the *** vectors are assumed due to the clearance between the inner tubes and the front ***,the major parts of the vectors are moved out through the bottom opening of the rear baffle,and other vectors produce a large circle between the two *** simulations are conducted to investigate the effects of the baffle on the heat exchanger using the Fluent *** k-εturbulence model is employed to calculate the flows along the heat exchanger.

关键词： Baffle P1V Shell and tube heat exchanger Cut off ratio CFD

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Technical Development of Simple Shear Deformation Experiments Using a Deformation-DIA Apparatus

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Journal of Earth Science 2010年第5期21卷 523-531页

作者： Tomohiro Ohuchi Takaaki Kawazoe Norimasa Nishiyama Yu Nishihara Tetsuo Irifune Geodynamics research Center Ehime University Senior research fellow Center Ehime University

Technical developments for simple shear deformation experiments at high pressures were made. The newly designed cell assembly can be compressed by deformation-DIA apparatuses with the MA 6-6 system, which consists of six second-stage tungsten carbide anvils （with a truncated edge length of 5 mm） and the anvil guide. Deformation of samples was barely observed during the compression process, showing that the shear strain of the deformed samples can be measured by the rotation of a strain marker. Simple shear deformation experiments on anhydrous and hydrous oli- vine aggregates were conducted under upper mantle conditions （pressures of 5.2-7.6 GPa and temperatures of 1 473-1 573 K）, and sample deformation with a shear strain of 7=0.8-1.2 was successfully achieved at a shear strain rate of 4.0×10^-5-7.5×10^-5 s^-1. The present study extended the pressure range of simple shear deformation experiments in the deformation-DIA apparatus from 3 GPa in an early study to 7.6 GPa at high temperatures.

关键词： simple shear deformation deformation-DIA MA 6-6 upper mantle.

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Higher-mode effect on the seismic responses of buildings with viscoelastic dampers

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Earthquake Engineering and Engineering Vibration 2002年第1期1卷 119-129页

作者： Meng-Hao Tsai Department of Civil Engineering Taiwan UniversityChinese Taipei Postdoctoral Research Fellow

In conventional modal analysis procedures,usually only a few dominant modes are required to describe the dynamic behavior of multi-degrees-of-freedom *** number of modes needed in the dynamic analysis depends on the higher-mode contribution to the structural response,which is called the higher-mode *** modal analysis approach, however,may not be directly applied to the dynamic analysis of viscoelastically damped *** is because the dynamic properties of the viscoelastic dampers depend on their vibration ***,the structural stiffness and damping contributed from those dampers would be different for each *** this study,the higher-mode effect is referred to as the response difference induced by the frequency-dependent property of viscoelastic dampers at higher *** analysis procedures for buildings with viscoelastic dampers distributed proportionally and non-proportionally to the stiffness of the buildings are developed to consider the higher-mode *** studies on shear-type viscoelastically damped building models are conducted to examine the accuracy of the proposed procedures and to investigate the significance of the higher-mode effect on their seismic *** damper models are used to estimate the peak damper forces in the proposed procedures. Study results reveal that the higher-mode effect is significant for long-period viscoelastically damped *** higher-mode effect on base shear is less significant than on story acceleration *** difference of the seismic response usually occurs at the top ***,the higher-mode effect may not be reduced by decreasing the damping ratio provided by the viscoelastic *** practical application,it is realized that the linear viscous damping model without considering the higher-mode effect may predict larger damper forces and hence,is on the conservative side.

关键词： model analysis viscoelastic dampers higher-mode effect

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Mapping urban building stocks for vulnerability assessment preliminary results

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International Journal of Digital Earth 2011年第S1期4卷 117-130页

作者： Keiko Saito Robin Spence Department of Architecture University of CambridgeCambridgeUK Cambridge Architectural research Ltd CambridgeUK Willis research fellow Willis Research Network

This paper discusses a methodology to collect building inventory data by combining image processing techniques,field work or tools such as Google Street View and applying statistical *** the methodology outlined in Marinescu(2002),a family of Gabor filters are first constructed,which are then applied to an optical high-resolution *** output from the processed image is segmented using Self-Organising *** paper examines the relationship between the segmented areas in the image and the building type distribution within each segmented area,by deriving the distribution from field *** relationship between the average number of buildings in these cells against the number of grid cells allocated to each segmentation cluster is also ***,using these results,the overall building inventory distribution for the whole of the case study site of Pylos is presented.

关键词： building inventory data collection remote sensing high-resolution optical satellite images Gabor filters Self-Organising Maps field data

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Treatment of Helicobacter pylori in surgical practice:A randomised trial of triple versus quadruple therapy in a rural district general hospital

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World Journal of Gastroenterology 2008年第24期14卷 3855-3860页

作者： Siok Siong Ching Sivakumaran Sabanathan Lloyd R Jenkinson Clinical research fellow in General Surgery Leeds General Infirmary Department of Surgery Ysbyty Gwynedd

AIM: To compare a lansoprazole-based triple versus quadruple therapy for Helicobacter pylori (H pylori) eradication with emphasis on side effect prof ile,patient compliance and eradication rate at a rural district general hospital in Wales,United Kingdom. METHODS: One hundred one patients with H pylori infection were included in the study. Patients were randomised to receive triple therapy comprising of lansoprazole 30 mg,amoxycillin 1 g,clarithromycin 500 mg,all b.d. (LAC),or quadruple therapy comprising of lansoprazole 30 mg b.d.,metronidazole 500 mg t.d.s.,bismuth subcitrate 240 mg b.d.,and tetracycline chloride 500 mg q.d.s. (LMBT). Cure was defi ned as a negative 13C urea breath test 2 mo after treatment. RESULTS: Seven patients were withdrawn after randomisation. Fifty patients were assigned to LAC group and 44 to LMBT group. The intention-to-treat cure rates were 92% and 91%,whereas the per-protocol cure rates were 92% and 97%,respectively. Side effects were common,with 56% experiencingmoderate to severe symptoms in the LAC group and 59% in the LMBT group. Symptoms of vomiting,diarrhoea and black stools were significantly more common in the LMBT group. Patient compliance was 100% for triple therapy and 86% for quadruple therapy (P < 0.01). One-third of patients in both groups were still taking acid-reducing medications at six-month follow-up. CONCLUSION: One-week triple and quadruple therapies have similar intention-to-treat eradication rates. Certain side effects are more common with quadruple therapy,which can compromise patient compliance. Patient education or modifi cations to the regimen are alternative options to improve compliance of the quadruple regimen.

关键词： Helicobacter pylori Triple therapy Quadruple therapy Side effects Treatment compliance Eradication rate

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