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Low-modal-crosstalk doped-fiber amplifiers in few-mode-fiber-based systems

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Photonics research 2024年第08期12卷 1768-1775页

作者： SHUAILUO HUANG LEI SHEN GANG QIAO YUANPENG DING YUYANG GAO JIAN CUI BAOLONG ZHU SIYUAN LIU MINGQING ZUO JINGLONG ZHU LEI ZHANG JIE LUO YONGQI HE ZHANGYUAN CHEN JUHAO LI State Key Laboratory of Advanced Optical Communication Systems and Networks Peking University State Key Laboratory of Optical Fiber and Cable Manufacture Technology Yangtze Optical Fibre and Cable Joint Stock Limited Company School of Computer and Communication Engineering University of Science and Technology Beijing Department of Networks China Mobile Communications Group Co. Ltd. Department of Fundamental Network Technology China Mobile Research Institute Pengcheng Laboratory

Independent light propagation through one or multiple modes is commonly considered as a basic demand for mode manipulation in few-mode fiber（FMF）-or multimode fiber（MMF）-based optical systems such as transmission links, optical fiber lasers, or distributed optical fiber sensors. However, the insertion of doped-fiber amplifiers always kills the entire effort by inducing significant modal crosstalk. In this paper, we propose the design of doped-fiber amplifiers in FMF-based systems adopting identical multiple-ring-core（MRC） index profiles for both passive and doped fibers to achieve low modal crosstalk. We develop the direct-glass-transition（DGT） modified chemical vapor deposition（MCVD） processing for precise fabrication of few-mode erbium-doped fibers（FM-EDFs） with MRC profiles of both refractive index and erbium-ion doping distribution. Then, a few-mode erbium-doped-fiber amplifier（FM-EDFA） with a maximum gain of 26.08 dB and differential modal gain（DMG） of 2.3 dB is realized based on fabricated FM-EDF matched with a transmission FMF supporting four linearly polarized（LP） modes. With the insertion of the FM-EDFA, 60 + 60 km simultaneous LP01∕LP11∕LP21∕LP02transmission without inter-modal multiple-input multiple-output digital signal processing（MIMO-DSP） is successfully demonstrated. The proposed design of low-modal-crosstalk doped-fiber amplifiers provides, to our knowledge, new insights into mode manipulation methods in various applications. ? 2024 Chinese Laser Press

关键词： Chemical vapor deposition Erbium fibers Few mode fibers High power fiber lasers Multimode fibers Signal processing

Stackelberg Game for Wireless Powered and Backscattering Enabled Sensor Networks

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China Communications 2024年第3期21卷 189-204页

作者： Lyu Bin Cao Yi Wang Shuai Guo Haiyan Hao Chengyao Key Laboratory of Ministry of Education in Broadband Wireless Communication and Sensor Network Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China Jiangsu Engineering research Center of Novel Optical Fiber Technology and Communication Network Suzhou 215006China Guangdong-Hong Kong-Macao joint Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

This paper investigates a wireless powered and backscattering enabled sensor network based on the non-linear energy harvesting model, where the power beacon(PB) delivers energy signals to wireless sensors to enable their passive backscattering and active transmission to the access point(AP). We propose an efficient time scheduling scheme for network performance enhancement, based on which each sensor can always harvest energy from the PB over the entire block except its time slots allocated for passive and active information delivery. Considering the PB and wireless sensors are from two selfish service providers, we use the Stackelberg game to model the energy interaction among them. To address the non-convexity of the leader-level problem, we propose to decompose the original problem into two subproblems and solve them iteratively in an alternating manner. Specifically, the successive convex approximation, semi-definite relaxation(SDR) and variable substitution techniques are applied to find a nearoptimal solution. To evaluate the performance loss caused by the interaction between two providers, we further investigate the social welfare maximization problem. Numerical results demonstrate that compared to the benchmark schemes, the proposed scheme can achieve up to 35.4% and 38.7% utility gain for the leader and the follower, respectively.

关键词： backscatter communication energy interaction stackelberg game wireless powered sensor network

Dendritic nanomedicine enhances chemoimmunotherapy by disturbing metabolism of cancer-associated fibroblasts for deep penetration and activating function of immune cells

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3680-3696页

作者： Yunkun Li Xiaoding Shen Haitao Ding Yuxin Zhang Dayi Pan Liping Su Yahui Wu Zaixiang Fang Jie Zhoua Qiyong Gong Kui Luo Department of Radiology Huaxi MR Research Center(HMRRC)Frontiers Science Center for Disease-Related Molecular NetworkState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Functional and Molecular Imaging Key Laboratory of Sichuan Province and Research Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu 610041China Department of Radiology West China Xiamen Hospital of Sichuan UniversityXiamen 361021China

Inefficient drug penetration hurdled by the stroma in the tumor tissue leads to a diminished therapeutic effect for drugs and a reduced infiltration level of immune ***,we constructed a PEGylated dendritic epirubicin(Epi)prodrug(Epi-P4D)to regulate the metabolism of cancer-associated fibroblasts(CAFs),thus enhancing Epi penetration into both multicellular tumor spheroids(MTSs)and tumor tissues in mouse colon cancer(CT26),mouse breast cancer(4T1)and human breast cancer(MDA-MB-231)*** cytotoxicity against CT26 MTSs and remarkable antitumor efficacy of Epi-P4D were ascribed to reduced fibronectin,α-SMA,and collagen ***,thinning of the tumor tissue stroma and efficient eradication of tumor cells promoted the immunogenic cell death effect for dendritic cell(DC)maturation and subsequent immune activation,including elevating the CD4^(+)T cell population,reducing CD4^(+)and CD8^(+)T cell hyperactivation and exhaustion,and amplifying the natural killer(NK)cell proportion and effectively activating *** a result,this dendritic nanomedicine thinned the stroma of tumor tissues to enhance drug penetration and facilitate immune cell infiltration for elevated antitumor efficacy.

关键词： Dendritic prodrug Enhanced penetration Metabolic intervention Cancer-associated fibroblasts Immunogenic cell death Chemotherapy Immunotherapy Immune microenvironment reconstitution

Design of Resilient Sensor Networks Balancing Resilience and Efficiency

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International Journal of Disaster Risk Science 2024年第1期15卷 107-115页

作者： Sergey N.Vecherin Kiril D.Ratmanski Luke Hogewood Igor Linkov Cold Regions research and Engineering Laboratory Engineering Research and Development CenterHanoverNH 03755USA Environmental Laboratory Engineering Research and Development CenterVicksburgMS 39180USA

In recent years,the notion of resilience has been developed and applied in many technical areas,becoming exceptionally pertinent to disaster risk *** a disaster situation,accurate sensing information is the key to efficient recovery *** general,resilience aims to minimize the impact of disruptions to systems through the fast recovery of critical functionality,but resilient design may require redundancy and could increase *** this article,we describe a method based on binary linear programming for sensor network design balancing efficiency with *** application of the developed framework is demonstrated for the case of interior building surveillance utilizing infrared sensors in both twoand three-dimensional *** method provides optimal sensor placement,taking into account critical functionality and a desired level of resilience and considering sensor type and *** problem formulation,resilience requirements,and application of the optimization algorithm are described in *** of sensor locations with and without resilience requirements shows that resilient configuration requires redundancy in number of sensors and their intelligent *** tasks are successfully solved by the described method,which can be applied to strengthen the resilience of sensor networks by *** proposed methodology is suitable for large-scale optimization problems with many sensors and extensive coverage areas.

关键词： Binary linear programming Optimal sensor placement Redundant networks Resilience and efciency Resilient sensor networks

Navigating micro- and nano-motors/swimmers with machine learning: Challenges and future directions

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ChemPhysMater

ChemPhysMater 2024年第3期3卷 273-283页

作者： Jueyi Xue Hamid Alinejad-Rokny Kang Liang School of Chemical Engineering and Australian Centre for nanomedicine UNSW SydneySydneyNSW 2052Australia UNSW BioMedical Machine Learning Laboratory The Graduate School of Biomedical EngineeringUNSW SydneyRandwickNSW 2052Australia The Graduate School of Biomedical Engineering UNSW SydneyRandwickNSW 2052Australia

Micro-/nano-motors(MNMs)or swimmers are minuscule machines that can convert various forms of energy,such as chemical,electrical,or magnetic energy,into *** devices have attracted significant attention owing to their potential application in a wide range of fields such as drug delivery,sensing,and ***,owing to their diverse shapes,sizes,and structural/chemical compositions,the development of MNMs faces several challenges,such as understanding their structure-function relationships,which is crucial for achieving precise control over their motion within complex *** recent years,machine learning techniques have shown promise in addressing these challenges and improving the performance of *** learning techniques can analyze large amounts of data,learn from patterns,and make predictions,thereby enabling MNMs to navigate complex environments,avoid obstacles,and perform tasks with higher efficiency and *** review introduces the current state-of-the-art machine learning techniques in MNM research,with a particular focus on employing machine learning to understand and manipulate the navigation and locomotion of ***,we discuss the challenges and opportunities in this field and suggest future research directions.

关键词： Micro/nano-motors Active matter Machine learning Reinforcement learning

A multi-parameter-induced activation of gas therapeutic platform to remarkably amplify photodynamic therapy efficacy

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Science China Chemistry 2024年第7期67卷 2403-2411页

作者： Jie Sun Ziwen Zhang Hongyu Wu Xuemei Dong Chengjun Dong Lixin Sun Zhiqian Guo Yingchao Liu Xianfeng Gu Chunchang Zhao Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist joint research Center Institute of Fine ChemicalsSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China Department of Medicinal Chemistry School of PharmacyFudan UniversityShanghai 201203China Shandong Provincial Hospital Affiliated to Shandong First Medical University Shandong First Medical University&Shandong Academy of Medical ScienceJinan 250021China

Gas therapy(GT)combined with photodynamic therapy(PDT)is an effective strategy to compensate for the PDT limitation caused by the hypoxic tumor microenvironment,which can greatly improve PDT *** uncontrolled leakage of gas molecules during delivery seriously hinders its practical biological ***,we report a multifunction nanomedicine that enables precise gas therapy(including carbon monoxide(CO)release and H_(2)S depletion)using a multi-parameter-induced activation gas release strategy,enlarging the PDT *** nanomedicine uses a disulfide bond to covalently link a photosensitizer with the CO donor 3-hydroxyflavone(3-HF).The disulfide bond can be specifically consumed in H_(2)S-rich tumor areas,releasing the CO donor(3-HF),and also depleting H_(2)*** importantly,the photo-controlled production of^(1)O_(2)can induce 3-HF precise release of CO in the tumor *** H_(2)S,light,and^(1)O_(2)multi-parameter-induced activation of gas release strategy ensures the accuracy of GT to amplify PDT *** expected,in vitro and in vivo investigations show that GT makes up for the PDT limitation,exhibiting the highest tumor therapeutic *** multi-parameter-activated design strategy provides a new way to improve the precision and efficacy of multimodal synergistic therapy of tumors.

关键词： gas therapy precision gas release hydrogen sulfide depletion photodynamic therapy multimodal synergistic therapy

research progress of integrated optical gyroscope

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Chinese Optics Letters 2024年第3期22卷 42-49页

作者：郭宏杰刘海锋雷明谭满清宋志刚 Institute of Semiconductors Chinese Academy of SciencesBeijing 100083China College of Materials Science and Opto-electronics Technology University of Chinese Academy of SciencesBeijing 100049China Beijing Huairou Instruments and sensors Co. Ltd.Beijing 101400China Beijing Institute of Automation and Control Equipment Key Laboratory of National Defense Science and Technology of Inertial TechnologyBeijing 100074China

Integrated optical gyroscopes(IOGs)have been an efficient tool for numerous applications in various fields,including inertial navigation,flight control,and earthquake ***,we review the progress of integrated optical gyroscopes based on two categories of integrated interferometric optical gyroscopes(IIOGs)and integrated resonant optical gyroscopes(IROGs).

关键词： integrated optical gyroscopes interferometric optical gyroscopes integrated resonant optical gyroscopes

Reply to Comment on“Chemical vapor deposition synthesis and Raman scattering investigation of quasi-one-dimensional ZrS_(3) nanoflakes”

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Nano research 2024年第9期17卷 8649-8650页

作者： Yang Chen Yuanyuan Jin Junqiang Yang Yizhang Ren Zhuojun Duan Xiao Liu Jian Sun Song Liu Xukun Zhu Xidong Duan Institute of Chemical Biology and nanomedicine(ICBN) College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China Hunan Key Laboratory of Two-Dimensional Materials and State Key Laboratory for Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China School of Physics and Electronics Central South UniversityChangsha 410083China

1 Introduction Thanks very much for *** taking time to comment on our recent paper regarding“Chemical vapor deposition synthesis and Raman scattering investigation of quasi-one-dimensional ZrS_(3) nanoflakes”.We summarize the suggestions of *** as made in the comment[1].First,*** suggested that there are just three peaks of two S 2p doublets in Fig.2(b)in the original paper[1],which is inconsistent to the four peaks of previous reports[2-4].Second,*** mentioned that the ratio of two S 2p doublets is helpful to identify the sulfur vacancies,which have a great impact on the n-type semiconducting nature of ZrS_(3).Third,*** mentioned that Zr 3d peak appearing at 184.7 eV is wider than previous reports[2,4],which may be accounted by the appearance of ZrS_(2)O,and Zr remains in the tetravalent state.

关键词： state. synthesis quasi

Quantitative Applications of Weather Satellite Data for Nowcasting:Progress and Challenges

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Journal of Meteorological research 2024年第3期38卷 399-413页

作者： Jun LI Jing ZHENG Bo LI Min MIN Yanan LIU Chian-Yi LIU Zhenglong LI WPaul MENZEL Timothy J.SCHMIT John L.CINTINEO Scott LINDSTROM Scott BACHMEIER Yunheng XUE Yayu MA Di DI Han LIN Innovation Centre for Fengyun Meteorological Satellite(FYSIC) National Satellite Meteorological CentreChina Meteorological AdministrationBeijing100081China School of Atmospheric Sciences and Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen University and Southern Laboratory of Ocean Science and EngineeringZhuhai519082China Key Laboratory of Geographic Information Science(Ministry of Education) East China Normal UniversityShanghai200241China research Center for Environmental Changes Academia SinicaTaipei11529China Cooperative Institute for Meteorological Satellite Studies University of Wisconsin-MadisonMadisonWI53706USA sensors and Calibration Branch STAR/NESDISMadisonWI53706USA Wuxi University Wuxi214105China School of Computer Science Chengdu University of Information TechnologyChengdu610225China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing210044China Key Laboratory of Spatial Data Mining and Information Sharing of Ministry of Education National and Local Joint Engineering Research Center of Satellite Geospatial Information TechnologyFuzhou UniversityFuzhou350108China

Monitoring and predicting highly localized weather events over a very short-term period,typically ranging from minutes to a few hours,are very important for decision makers and public *** these events usually relies on radar observations through monitoring and *** advanced high-resolution imaging and sounding observations from weather satellites,nowcasting can be enhanced by combining radar,satellite,and other data,while quantitative applications of those data for nowcasting are advanced through using machine learning *** applications include monitoring the location,impact area,intensity,water vapor,atmospheric instability,precipitation,physical properties,and optical properties of the severe storm at different stages(pre-convection,initiation,development,and decaying),identification of storm types(wind,snow,hail,etc.),and predicting the occurrence and evolution of the *** observations can provide information on the environmental characteristics in the preconvection stage and are very useful for situational awareness and storm *** paper provides an overview of recent progress on quantitative applications of satellite data in nowcasting and its challenges,and future perspectives are also addressed and discussed.

关键词： weather satellite quantitative applications nowcasting pre-convection