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Advances in the treatment of autism spectrum disorder:Wharton jelly mesenchymal stem cell transplantation

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World Journal of Methodology 2025年第1期15卷 72-79页

作者： Serdar Kabatas ErdinçCivelek Eyüp Can Savrunlu Umut Karaaslan Özlem Yıldız Erdal Karaöz Department of Neurosurgery University of Health Sciences TurkeyGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Pediatric Allergy-Immunology Institute of Health Sciences Marmara UniversityIstanbul 34865Türkiye Center for Stem Cell&Gene Therapy Research and Practice University of Health Sciences TurkeyIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry University of Health SciencesGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry Kocaeli University Faculty of MedicineKocaeli 41001Türkiye Center for Regenerative Medicine and Stem Cell Research&Manufacturing Liv HospitalIstanbul 34340Türkiye Department of Histology and Embryology Istinye UniversityFaculty of MedicineIstanbul 34010Türkiye Center for Stem Cell and Tissue Engineering Research and Practice Istinye UniversityIstanbul 34340Türkiye

BACKGROUND Autism spectrum disorder(ASD)is a complex neurodevelopmental disorder with multifaceted *** recent studies,neuroinflammation and immune dysregulation have come to the forefront in its *** are studies suggesting that stem cell therapy may be effective in the treatment of *** To evolve the landscape of ASD treatment,focusing on the potential benefits and safety of stem cell *** A detailed case report is presented,displaying the positive outcomes observed in a child who underwent intrathecal and intravenous Wharton’s jelly-derived mesenchymal stem cells(WJ-MSCs)transplantation combined with *** The study demonstrates a significant improvement in the child’s functional outcomes(Childhood Autism Rating Scale,Denver 2 Developmental Screening Test),especially in language and gross motor *** serious side effects were encountered during the 2-year *** The findings support the safety and effectiveness of WJ-MSC transplantation in managing ASD.

关键词： Autism spectrum disorder Neurorehabilitation Stem cell transplantation Wharton jelly mesenchymal stem cells Inflammation

NATO and Russia＇s Security Dilemma Within the European Union＇s Far Neighbors

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International Relations and Diplomacy 2016年第10期4卷 650-665页

作者： Ugur Ozgoker Serdar Yllmaz istanbul arel university lstanbul Turkey istanbul arel university istanbul Turkey

This paper presents a viewpoint for NATO and Russia＇s security dilemma by analyzing what happened in Georgia, Ukraine, Libya and Syria. At the end of the Cold War re-building of NATO, inheriting Missile defense System by the US government and Russia＇s growing concern regarding NATO＇s eastward expansion made clear that Russia will not abandon her sphere of influence. Thus, the main objective of this study is to analyze the questions of what is the motivation behind NATO＇s new strategy. This will be followed by another question NATO and EU enlargement will push Russia in what direction. The hypothesis of the study is that NATO＇s strategy of taking position in the areas where identified as Russia＇s backyard and sphere of influence is considered as ＂casus belli＂ by Russia. Therefore, Russia, despite NATO＇s involvement in the specified area, will not abandon these areas and will continue to use her energy resources and geopolitical advantages as a coercion, especially against NATO members among EU countries.

关键词： NATO Russia Middle-East Eurasia security dilemma sphere of influence

ON THE WEIGHTED VARIABLE EXPONENT AMALGAM SPACE W(L^(p(x)), L_m^q)

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Acta Mathematica Scientia 2014年第4期34卷 1098-1110页

作者： A. Turan GRKANLI Ismail AYDIN Department of Mathematics and Computer Science Faculty of Sciences and LettersIstanbul Arel UniversityTurkoba Mathallesi Erguvan Sokak No: 26/K34537Tepekent-BuyukcekmeceIstanbulTurkey Department of Mathematics Faculty of Arts and SciencesSinop University

In [4], a new family W（L^p（x）, Lm^q） of Wiener amalgam spaces was defined and investigated some properties of these spaces, where local component is a variable exponent Lebesgue space L^p（x）（R） and the global component is a weighted Lebesgue space Lm^q （R）. This present paper is a sequel to our work [4]. In Section 2, we discuss necessary and sufficient conditions for the equality W （L^p（x）, Lm^q） = L^q （R）. Later we give some characterization of Wiener amalgam space W （L^p（x）, Lm^q）.In Section 3 we define the Wiener amalgam space W （FL^p（x）, Lm^q） and investigate some properties of this space, where FL^p（x） is the image of L^p（x） under the Fourier transform. In Section 4, we discuss boundedness of the Hardy- Littlewood maximal operator between some Wiener amalgam spaces.

关键词： weighted Lebesgne space variable exponent Lebesgue

Non-performing Loans in Turkish Banking Sector and Balance Sheets Effects

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Journal of Modern Accounting and Auditing 2015年第12期11卷 677-686页

作者： Aylin Erdogdu istanbul arel university Istanbul Turkey

In the 21st century, while the scope of banking activities has been expanding every day, collecting deposits and providing credit remain as their main and most important functions. They transfer the collected funds thanks to the market confidence they create back to the market in terms of the credits they give. For the organizations operating in the banking sector, crediting is the highest revenue earning source. However, uncollected loans may disrupt the activities of banks and may reduce their effectiveness. Therefore, the control of bank credits has a particular importance in the bank balance sheets. In this study, the relationship between bank balance sheets and non-performing loans （NPL） will be analyzed using Granger causality test and vector autoregressive （VAR） method. This study aims to discuss the impact of NPL on balance sheets and contribute to making correct credit decisions. It also intends to assist to reduce the NPL ratios of banks and minimize the level of negativity in their financial statements.

关键词： Turkish banking sector non-performing loans (NPL) banks' balance sheets

Transition From Utopias to Dystopias： A Comparative Study on Brave New World and Nineteen Eighty-Four

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Journalism and Mass Communication 2014年第4期4卷 266-282页

作者： Murat Mengu istanbul arel university Istanbul Turkey

Due to the two world wars, social, political, and economic instability or corruption almost all over the world in the 20th century, man has been dragged into the state of hopelessness and despair. Moreover, the tradition and legacy of the past have begun to rot. Undoubtedly, such a change had a great influence upon the concept of ＂utopian society＂, involving ultimate perfection of all aspects of human life. In the same way, the quest for perfect society was proved to be futile. Thus, the emergence of anti-utopian fiction was unavoidable.

关键词：世界大战乌托邦人类生活社会不稳定

Eurasian Economic Union＇s Effect on Global Politics and the World Economic System

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International Relations and Diplomacy 2015年第10期3卷 699-714页

作者： Askm inci Sokmen istanbul arel university istanbul Turkey

The new Eurasian Economic Union （EEU） has now become a reality coming into effect today allowing free movement of trade, services and capital. Its treaty was signed on 29 May 2014 by the leaders of Belarus, Kazakhstan and Russia. EEU has an integrated single market of 176 million people and a gross domestic product （GDP） of over four trillion US Dollars. From the point view of Nye and Keohane＇s interdepence theory, this trade block formed under Moscow＇s leadership also begs the question, if the Soviet Union will also reunite and be re-established. Russia seems to look at it not just in economic terms, but as a way to expand Russian influence in the region. The biggest criticism of the union seems to be re-establishment of the crumbled Soviet Union. On the other hand Russia has wanted to launch talks with the newly born EEU despite the Ukraine Crisis. German Chancellor Angele Merkel has supported to establish a common economic space in the Eurasian Region including the focus countries of Eastern Partnership （an EU policy on closer ties with Armenia, Azerbaijan, Belarus, Georgia, Moldova and Ukraine）. A new Russia-led blocs as a better partner for the EU than the US could cause to deemphasize new Trans-Atlantic Treaty. Another point, the union is actively seeking to increase trade with East Asia. It commenced talks for official trade cooperation with Association of Southeast Asian Nations （ASEAN）. Therefore we can say that EEU includes strategic interests as well as economic interests for its members, especially for Russia. In order to link both Europe and East Asia, Russia seeks to develop its eastern regions to increase its access to Asian markets. Far East markets have become so important for Russia since the European Union and the United States imposed sanctions on Russia following crisis in Ukraine. In this article my aim is to analyze EEU effects on global politics and the World Economic System.

关键词： Russia Eurasian Economic Union geopolitics and geo-economy of Eurasia new power economicalbalance in global competition

Comparison of Low Rise Residential Industrialized Building Systems in Turkey

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Journal of Literature and Art Studies 2012年第9期2卷 864-871页

作者： Semih Goksel Yildirim istanbul arel university Istanbul Turkey

Industrialized building systems came into the agenda in response to requirements of earthquake resistance and rapid construction in Turkey after 1999 Izmit earthquake. CFS （cold-formed steel） framing system is able to meet the existing requirements in the field of low rise residential. But, objective comparison is required for the selection of structural systems used in low rise residentials. CFS system is compared with timber frame and reinforced concrete building systems in terms of design and applicability criterion in circumstances of Turkey, and the results of this comparison are presented in this study. In order to compare building systems objectively, a sample project, has been designed and studied on it. Three structural systems have been separately applied over this project designed in consideration of existing housing stock and preferences of the construction industry of Turkey Evaluation method with different values is selected in comparison and properties of three different structural systems are graded according to evaluation method. As a result of comparison, the CFS system is the most advantageous low rise residential prefabricated construction system in terms of design and applicability

关键词： low rise residential industrialization prefabricated reinforced concrete system CFS (cold-formed steel)frame timber frame

Making Sense of Public Relations as Culture Policy

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Journalism and Mass Communication 2016年第10期6卷 632-639页

作者： SedaMengu Murat Mengu istanbul university Istanbul Turkey istanbul arel university Istanbul Turkey

Culture is a process in which meaning is produced, distributed, consumed, materialised, re-produced infinitely and discussed with society. As meanings generally disperse extensively in different social groups through different associations, they display certain changes in time depending on their usage. Meanwhile, it is hard to define the public relations concept, because it may refer to different meanings even in the same culture. According to the assumptions pertaining to the public relations practices shaping the dominant discourse of the USA, language which produces certain cultural meanings also shapes the way we think and act. Thus, due to its ideological and discursive nature, public relations functions as a culture policy. Being an integral communication management configuring and directing the social sphere and the practices related to it, public relations refers to the concept of habitus introduced by Bourdieu inasmuch as habitus resides in the situations formed by actions that individuals learn throughout their lives. Culture policy; on the other hand, purports the effective participation of people in cultural life, their development in social, economic and cultural areas as well as the creation of convenient conditions to sustain it, which can be achieved with public relations practices. Public relations determines the culture policies in a society with regard to the structured discourses and actions and also acts as the mouthpiece of these policies. The purpose of public communication that is necessary for development and sustainability is to inform the public objectively in cultural, social, political and economic senses by obtaining feedback form them. For the purpose of administering sound public communication strategies in a society, public relations should direct the forms of public discourse. The purpose of this study is to put forth a critical evaluation based on the idea that for the realisation of effective and sensible communication policies in

关键词： culture public relations culture policy

The Most Significant Factors Influencing the Price of Gold： An Empirical Analysis of the US Market

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Economics World 2017年第5期5卷 399-406页

作者： Aylin Erdogdu istanbul arel university Rstanbul Turkey

Gold is always a precious metal for many hundred years. Semi flexible gold demand and supply chain determines international gold prices in the long term. USA is ranked the world’s largest gold producer. This study mainly aims to investigate the dynamic factors which affect the price of gold and determine the essential macro-economic variable that has the most important role during the process. This paper examines USA over 13 years applying a formal test for time series, which interrogate cointegration relationships, what is the affiliation between gold price and other factors, which are explained in detail below. The present study has used the monthly data from January, 2003 to June, 2016. Databases are provided by the Federal Reserve, the central bank of the United States, and United States Energy Information Administration. Data analysis was performed with software package EViews 8. Through the time series, an analysis has been carried out on Dow Jones Index, the US exchange rate, silver price, interest rate, oil price and inflation rate which are thought to influence the price of gold in the most significant way. The data analysis includes the determination of the conditional heteroscedastic model to estimate volatility. Therefore, the best fitting model to the data set, which is the exponential GARCH model, is preferred. In accordance with the results of the empirical analyses in the USA, the highest negative correlation is found between gold prices and US exchange rate. Secondly, a positive correlation is found among gold prices, silver prices, and oil prices. Another point which takes attention as a result of the study is that economic and political structural breaks weighed heavily, traders and hedgers from all over the world were able to drive prices up to incredible highs. The added valueof our study arises from the inclusion in the analysis of macro economic variables, which has proved to have crucial relevance for the price of gold in the context of the

关键词： economic growth US market traders and hedgers gold prices ARCH model GARCH model