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Colorectal cancer screening:The value of early detection and modern challenges

World Journal of Gastroenterology 2024年第20期30卷 2726-2730页

作者： Jian Li Zhi-Peng Li Wen-Jie Ruan Wei Wang Department of interventional Oncology Municipal Hospital Affiliated to Taizhou UniversityTaizhou 318000Zhejiang ProvinceChina School of Medicine Taizhou UniversityTaizhou 318000Zhejiang ProvinceChina

The screening of colorectal cancer(CRC)is pivotal for both the prevention and treatment of this disease,significantly improving early-stage tumor detection *** advancement not only boosts survival rates and quality of life for patients but also reduces the costs associated with ***,the adoption of CRC screening methods faces numerous challenges,including the technical limitations of both noninvasive and invasive methods in terms of sensitivity and ***,socioeconomic factors such as regional disparities,economic conditions,and varying levels of awareness affect screening *** coronavirus disease 2019 pandemic further intensified these challenges,leading to reduced screening participation and increased waiting ***,the growing prevalence of early-onset CRC necessitates innovative screening *** response,research into new methodologies,including artificial intelligence-based systems,aims to improve the precision and accessibility of *** measures by governments and health organizations to enhance CRC screening efforts are underway,including increased advocacy,improved service delivery,and international *** role of technological innovation and global health collaboration in advancing CRC screening is *** such as artificial intelligence and gene sequencing are set to revolutionize CRC screening,making a significant impact on the fight against this *** the rise in early-onset CRC,it is crucial for screening strategies to continually evolve,ensuring their effectiveness and applicability.

关键词： Colorectal cancer Early detection Economic implications Noninvasive tests Quality of life Survival rates Therapeutic modalities Technical challenges

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Contribution and Relevance of Transfontanellar Ultrasound in Newborns in Ouagadougou: Multicentre Study on 1000 Cases

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Open Journal of radiology 2024年第2期14卷 64-73页

作者： Ouedraogo Pakisba Ali Ouedraogo Nina-Astrid Somé Milckisédek Judickael Dabire Stive Arnauld Tankoano Ida Aida Napon Aischa Madina Nikiema Zakari Diallo Ousseini Lougue Sorgho Leonie Claudine Cisse Rabiou Department of Medical Imaging Ouahigouya Regional University Hospital Centre Ouahigouya University Ouahigouya Burkina Faso Department of Diagnostic and interventional radiology Bogodogo University Hospital Ouagadougou Burkina Faso Department of Medical Imaging Souro Sanon University Hospital Bobo Dioulasso Burkina Faso Medical Imaging service Yalgado Oudraogo University Hospital Ouagadougou Burkina Faso Department of Medical Imaging Charles de Gaulle Pediatric University Hospital Ouagadougou Burkina Faso Radiodiagnostic and Medical Imaging Laboratory Health Sciences Training and Research Unit Joseph Ki-Zerbo University Ouagadougou Burkina Faso

Objectives: To demonstrate the contribution and relevance of ETFs through the study of 1000 examination reports carried out in the medical imaging departments of the OUAGADOUGOU CHU. Material and method: Analytical descriptive study with retrospective collection, extended from 1st January 2020 to 1st January 2022. Results: Of the 1000 transfontanellar ultrasound reports, the mean age of patients was 7.61 +/ 7.5 days, with extremes of zero and 28 days. Sex was specified in 989 cases. Males accounted for 54.49% and females for 45.51%. 555 transfontanellar ultrasound were performed in 2020. 441 in 2021 and 4 in 2022. 61.9% of transfontanellar ultrasound were performed at the Bogodogo University Hospital, 205 at Charles de Gaulle and 176 at Tengandogo. Indications for transfontanellar ultrasound were dominated by neonatal distress (65.8%), followed by convulsions (10.2%) and prematurity (9.1%). Transfontanellar ultrasound was normal in 570 cases (57%) and abnormal in 430 cases (43%). Abnormalities were dominated by haemorrhage and ischaemic lesions in 66.28% (285) and 21.63% (93) of cases respectively. In the group of normal transfontanellar ultrasound, neonatal distress represented 59.65% of indications and prematurity 10.7% of indications. As for abnormal transfontanellar ultrasound, neonatal suffering accounted for 73.95% of indications and convulsions for 12.56%. The average age ofpatients with an abnormal transfontanellar ultrasound was 8.74 days +/ 7.89 days. The indication for investigations was relevant in 42.2% of cases and irrelevant in 57.8%;of the transfontanellar ultrasound with relevant indications, 0.71 were normal and 99.29 abnormal;of the transfontanellar ultrasound with irrelevant indications, the transfontanellar ultrasound was normal in 98.1% and abnormal in 1.9%. Conclusion: Transfontanellar ultrasound is an important part of ultrasound in current practice. Haemorrhage, anoxic-ischaemic lesions and hydrocephalus are the most frequent pathologies fou

关键词： Transfontanellar Ultrasound Neonatal Distress Relevance

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Sequential or simultaneous transarterial chemoembolization and radiofrequency ablation for hepatocellular carcinoma within the Milan criteria:A retrospective real-world study

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Portal Hypertension & Cirrhosis 2024年第2期3卷 105-115页

作者： Jianwei Liu Minmin Sun Zhiliang Hu Jie Wang Caixia Lu Ya Gao Cuijuan He Yeye Wu Jian Zhai Yong Xia Xiaorong Pan Kui Wang Department of Hepatic Surgery II Third Affiliated Hospital of Naval Medical University(Eastern Hepatobiliary Surgery Hospital)ShanghaiChina Department of Hepatic Surgery I Third Affiliated Hospital of Naval Medical University(Eastern Hepatobiliary Surgery Hospital)ShanghaiChina Department of Clinical Research Institute Third Affiliated Hospital of Naval Medical University(Eastern Hepatobiliary Surgery Hospital)ShanghaiChina Department II of interventional radiology Third Affiliated Hospital of Naval Medical University(Eastern Hepatobiliary Surgery Hospital)ShanghaiChina Department of Hepatic Surgery IV Third Affiliated Hospital of Naval Medical University(Eastern Hepatobiliary Surgery Hospital)ShanghaiChina Shanghai Baoshan District Songnan Town Community Health service Center ShanghaiChina

Aims:Few studies have investigated differences in sequential transarterial chemoembolization(TACE),radiofrequency ablation(RFA),and simultaneous RFA-TACE for the treatment of hepatocellular carcinoma(HCC)using the Milan *** study explored the differences in safety and prognosis between sequential TACE-RFA and simultaneous ***:This retrospective real-world study included 109 patients with HCC within the Milan criteria who underwent sequential TACE-RFA(n=75)or simultaneous RFA-TACE(n=34)at the Eastern Hepatobiliary Surgery Hospital between January 2017 and *** complications,length of hospital stay,and long-term prognosis were *** median follow-up duration of these patients was 39.1 *** survival(OS)and time to tumor recurrence(TTR)curves were plotted using the Kaplan−Meier method and were compared using the logarithmic rank *** risk factors for OS and tumor recurrence(TR)were analyzed using the Cox risk regression ***:Multivariate analysis showed that tumor diameter>3 cm(hazard ratio[HR]:2.201,95%confidence interval[CI]:1.106-4.378,p=0.025;HR:2.236,95%CI:1.271-3.934,p=0.005,respectively)and alphafetoprotein(AFP)>400μg/L(HR:2.362,95%CI:1.195-4.668,p=0.013;HR:1.798,95%CI:1.048-3.086,p=0.033,respectively)were independent risk factors for OS and TTR,whereas the presence of multiple tumors(HR:2.352,95%CI:1.127-4.907,p=0.023)was an independent risk factor for *** RFA-TACE did not have an effect on OS or *** propensity score-matched,comparable results were obtained and RFATACE still had no effect on OS or *** significant differences were observed in grade III/IV complications(2/75[2.7%]vs.1/34[2.9%],p=1.000)between the two ***,the RFA-TACE group had fewer complications than the TACE-RFA group(24/34[70.6%]vs.66/75[88.0%],p=0.026).The RFA-TACE group had a shorter hospital stay and less total cost during hospitalization compared with the TACE-RFA group(6.0 vs.10.0 da

关键词： complications hepatocellular carcinoma prognosis radiofrequency ablation transarterial chemoembolization

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Chinese expert consensus on refined diagnosis,treatment,and management of advanced primary liver cancer(2023 edition)

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肝脏研究（英文） 2024年第2期8卷 61-71页

作者： Xiufeng Liu Feng Xia Yue Chen Huichuan Sun Zhengqiang Yang Bo Chen Ming Zhao Xinyu Bi Tao Peng Aizier Ainiwaer Zhiwen Luo Fusheng Wang Yinying Lu National Clinical Research Center for Infectious Diseases Society of Hepatology,Beijing Medical Association Translational Medicine Branch,China Association of Gerontology and Geriatrics Department of Medical Oncology Bayi Hospital Affiliated to Nanjing Chinese Medical University NanjingJiangsuChina Department of Hepatobiliary Surgery Southwest HospitalArmy Medical University ChongqingChina Senior Department of Hepatology The Fifth Medical Center of PLA General HospitalBeijingChina Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina Department of interventional Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Minimally Invasive interventional Therapy Liver Cancer Study and Service GroupSun Yat-sen University Cancer CenterGuangzhouGuangdongChina Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxiChina Senior Department of Infectious Diseases The Fifth Medical Center of PLA General HospitalBeijingChina Comprehensive Liver Cancer Center The Fifth Medical Center of PLA General HospitalBeijingChina

Hepatocellular carcinoma(HCC),commonly known as primary liver cancer,is a major cause of malignant tumors and cancer-related deaths in China,accounting for approximately 85％of all cancer cases in the *** guidelines have been used to diagnose and treat liver ***,these guidelines provide a broad definition for classifying advanced liver cancer,with an emphasis on a singular approach,without considering treatment options for individual ***,it is necessary to establish a comprehensive and practical expert consensus,specifically for China,to enhance the diagnosis and treatment of HCC using the Delphi *** classification criteria were refined for Chinese patients with HCC,and the corresponding optimal treatment regimen recommendations were *** recommendations took into account various factors,including tumor characteristics,vascular tumor thrombus grade,distant metastasis,liver function status,portal hypertension,and the hepatitis B virus replication status of patients with primary HCC,along with treatment *** findings and rec-ommendations provide detailed,scientific,and reasonable individualized diagnosis and treatment strategies for clinicians.

关键词： Hepatocellular carcinoma (HCC) Targeted therapy Immunotherapy Refined diagnosis and treatment Expert consensus

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The role of interventional radiology in trauma

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介入放射学杂志 2007年第3期16卷 213-215页

作者： Douglas M.Coldwell Department of interventional radiology University of Texas Southwestern Medical Center Dallas

Introduction interventional radiology has evolved into a specialty having enormous input into the care of the traumatized *** all hospitals,regardless of size,the interventional Radiologist must consider their relatio... 详细信息

关键词：放射医学创伤外科学外伤服务

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Findings on intraprocedural non-contrast computed tomographic imaging following hepatic artery embolization are associated with development of contrast-induced nephropathy

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World Journal of Nephrology 2020年第2期9卷 33-42页

作者： Mohamed M Soliman Debkumar Sarkar Ilya Glezerman Majid Maybody interventional radiology service Memorial Sloan Kettering Cancer CenterNew YorkNY 10065United States Department of Medicine Memorial Sloan Kettering Cancer CenterNew YorkNY 10065United States

BACKGROUND Contrast-induced nephropathy(CIN)is a reversible form of acute kidney injury that occurs within 48-72 h of exposure to intravascular contrast *** is the third leading cause of hospital-acquired acute kidney injury and accounts for 12%of such *** factors for CIN development can be divided into patientand *** former includes pre-existing chronic renal insufficiency and diabetes *** latter includes high contrast volume and repeated exposure over 72 *** incidence of CIN is relatively low(up to 5%)in patients with intact renal ***,in patients with known chronic renal insufficiency,the incidence can reach up to 27%.AIM To examine the association between renal enhancement pattern on non-contrast enhanced computed tomographic(CT)images obtained immediately following hepatic artery embolization with development of *** Retrospective review of all patients who underwent hepatic artery embolization between 01/2010 and 01/2011(n=162)was *** without intraprocedural CT imaging(n=51),combined embolization/ablation(n=6)and those with chronic kidney disease(n=21)were *** study group comprised of 84 patients with 106 *** was defined as 25%increase above baseline serum creatinine or absolute increase≥0.5 mg/dL within 72 h ***-embolization CT was reviewed for renal enhancement patterns and presence of renal artery *** association between noncontrast CT findings and CIN development was examined by Fisher’s Exact *** CIN occurred in 11/106(10.3%)procedures(Group A,n=10).The renal enhancement pattern in patients who did not experience CIN(Group B,n=74 with 95/106 procedures)was late excretory in 93/95(98%)and early excretory(EE)in 2/95(2%).However,in Group A,there was a significantly higher rate of EE pattern(6/11,55%)compared to late excretory pattern(5/11)(P<0.001).A significantly higher percentage of patients that developed CIN had re

关键词： Hepatic artery embolization Non-contrast computed tomographic Contrastinduced nephropathy Renal enhancement pattern Intra-arterial Renal artery calcification

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Interest of thoracic ultrasound after cardiac surgery or interventional cardiology

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World Journal of Cardiology 2024年第3期16卷 118-125页

作者： Martin Boussuges Philippe Blanc Fabienne Bregeon Alain Boussuges service de Pneumologie Centre Hospitalier Universitaire Sud ReunionSaint Pierre 97410Ile de la ReunionFrance Department of Cardiac and Pulmonary Rehabilitation Ste Clotilde&YlangYlang Rehabilitation CenterSainte Clotilde 97491Ile de la ReunionFrance service d’Explorations Fonctionnelles Respiratoires Centre Hospitalier Universitaire NordAssistance Publique des Hôpitaux de MarseilleMarseille 13015France Institut Hospitalo-Universitaire-Méditerranée Infection Aix Marseille UniversitéMarseille 13005France Center for Cardiovascular and Nutrition Research Aix Marseille UniversitéInstitut National de la Santéet de la Recherche MédicaleInstitut National de Recherche pour l’Agriculturel’Alimentation et l’EnvironnementMarseille 13005France

Thoracic ultrasound has attracted much interest in detecting pleural effusion or pulmonary consolidation after cardiac *** 2016,Trovato reported,in the World Journal of Cardiology,the interest of using,in addition to echocardiography,thoracic *** this editorial,we highlight the value of assessing diaphragm function after cardiac surgery and interventional cardiology *** factors are able to impair diaphragm function after such *** motion may be decreased by chest pain secondary to sternotomy,pleural effusion or impaired muscle *** paralysis may be secondary to phrenic nerve damage complicating cardiac surgery or atrial fibrillation *** may be ***,respi-ratory troubles induced by diaphragm dysfunction are frequently attributed to pre-existing heart disease or pulmonary complications secondary to *** addition,elevated hemidiaphragm secondary to diaphragm dysfunction is sometimes not observed on chest X-ray performed in supine position in the intensive care *** of diaphragm function by ultrasound during the recovery period appears *** hemidiaphragms can be studied by two complementary ultrasound *** mobility of each hemidiaphragms is measured by M-mode *** addition,recording the percentage of inspiratory thickening provides important information about the quality of muscle *** two approaches make it possible to detect hemidiaphragm paralysis or *** a diagnosis is important because persistent diaphragm dysfunction after cardiac surgery has been shown to be associated with adverse respiratory *** respiratory physio-therapy is able to improve respiratory function through strengthening of the inspiratory muscles *** and accessory inspiratory muscles.

关键词： Ultrasonography Diaphragm Phrenic nerve Hemidiaphragm Thickening fraction Physiotherapy

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Impact of body mass index in elderly patients treated with laparoscopic liver resection for hepatocellular carcinoma

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World Journal of Gastrointestinal Surgery 2023年第1期15卷 72-81页

作者： Maria Conticchio Riccardo Inchingolo Antonella Delvecchio Francesca Ratti Maximiliano Gelli Massimiliano Ferdinando Anelli Alexis Laurent Giulio Cesare Vitali Paolo Magistri Giacomo Assirati Emanuele Felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi Fabrizio di Benedetto Nicola de’Angelis Javier Briceño Antonio Rampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo Unit of Hepato-Pancreatic-Biliary Surgery “F.Miulli”Regional General HospitalBari 70021Italy interventional radiology Unit “F.Miulli”Regional General HospitalBari 70021Italy Unit of Hepatobiliary Surgery San Raffaele HospitalMilano 20132Italy Departement de Chirurgie Viscérale Gustave Roussy Cancer Campus Grand ParisParis 94800France Unit of Oncologic and Pancreatic Surgery Hospital University Reina SofíaCordoba 14004Spain Assistance Publique-Hôpitaux de Paris Department of Digestive and Hepatobiliary SurgeryCentre Hospitalier Universitaire Henri MondorCréteilParis 94000France service of Abdominal Surgery Poliambulanza FoundationBrescia 25124Italy Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 41121Italy Institut de Recherche Contre les Cancers de l’Appareil Digestif(IRCAD) Strasbourg 67000France service de Chirurgie Viscérale et Digestive Nouvel Hôpital CivilStrasbourg 67000France Department of Surgery Hôpital Robert DebréReims 51092France interventional radiology Unit Niguarda HospitalMilan 20162Italy Department of Surgery Centre HepatobiliaireHopital Paul BrousseParis 94000France

BACKGROUND The impact of obesity on surgical outcomes in elderly patients candidate for liver surgery is still *** To evaluate the impact of high body mass index(BMI)on perioperative and oncological outcome in elderly patients(>70 years old)treated with laparoscopic liver resection for hepatocellular carcinoma(HCC).METHODS Retrospective multicenter study including 224 elderly patients(>70 years old)operated by laparoscopy for HCC(196 with a BMI<30 and 28 with BMI≥30),observed from January 2009 to January *** After propensity score matching,patients in two groups presented comparable results,in terms of operative time(median range:200 min vs 205 min,P=0.7 respectively in non-obese and obese patients),complications rate(22%vs 26%,P=1.0),length of hospital stay(median range:4.5 d vs 6.0 d,P=0.1).There are no significant differences in terms of short-and long-term postoperative *** The present study showed that BMI did not impact perioperative and oncologic outcomes in elderly patients treated by laparoscopic resection for HCC.

关键词： Hepatocellular carcinoma Body mass index Laparoscopy Surgical resection Elderly patients Propensity score matching

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Estimation of successful capping with complete aspiration of bladder via nephroureterostomy tube

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World Journal of Clinical Urology 2020年第1期9卷 1-8页

作者： Majid Maybody Wesley K Shay Deborah A Fleischer Meier Hsu Chaya Moskowitz Department of radiology Interventional Radiology ServiceMemorial Sloan Kettering Cancer CenterNew YorkNY 10065United States Department of Biostatistics and Epidemiology Memorial Sloan Kettering Cancer CenterNew YorkNY 10065United States

BACKGROUND Ureteral stent and nephroureterostomy tube(NUT)are treatments of ureteral *** stent provides better quality of *** of NUT is desired whenever *** To assess outcomes of capping trial among cancer patients with complete aspiration of retained contrast from bladder via *** Our Institutional Review Board approved retrospective review of all NUT placement,NUT exchange and conversion of nephrostomy catheter into NUT performed during June 2013 to June 2015(n=578).Cases were excluded due to lack of imaging of bladder(n=37),incomplete aspiration of bladder(n=324),no attempt at capping NUT(n=166),and patients with confounding factors interfering with results of capping trial including non-compliant bladder,bladder outlet obstruction and catheter malposition(n=14).Study group consisted of 37 procedures in 34 patients(male 19,female 15,age 2-83 years,average 58,median 61)most with cancer(prostate 8,endometrial 5,bladder 4,colorectal 4,breast 2,gastric 2,neuroblastoma 2,cervical 1,ovarian 1,renal 1,sarcoma 1,urothelial 1 and testicular 1)and one with Crohn’s *** records were reviewed to assess outcomes of capping *** 95%confidence intervals(95%CI)were *** Among patients with complete aspiration of retained contrast,30(81%,95%CI:0.65-0.92)catheters were successfully capped(range 12-94 d,average 40,median 24.5)until planned conversion to internal stent(23),routine exchange(5),removal(1)or death unrelated to catheter(1).Seven capping trials(19%,95%CI:0.08-0.35)were unsuccessful(range 2-22 d,average 12,median 10)due to leakage(3),elevated creatinine(2),fever/hematuria(1)and nausea/vomiting(1).CONCLUSION Capping trial success among patients with complete aspiration of retained contrast/urine from bladder via NUT appears high.

关键词： Nephroureterostomy tube Ureteral stent Capping trial Internalization Conversion Percutaneous nephrostomy

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Peri-operative score for elderly patients with resectable hepatocellular carcinoma

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World Journal of Hepatology 2023年第12期15卷 1307-1314页

作者： Maria Conticchio Riccardo Inchingolo Antonella Delvecchio Francesca Ratti Maximiliano Gelli Massimiliano Ferdinando Anelli Alexis Laurent Giulio Cesare Vitali Paolo Magistri Giacomo Assirati Emanuele Felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi Fabrizio di Benedetto Nicola de'Angelis Javier Briceño Antonio Rampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo Unit of Hepato-Pancreatic-Biliary Surgery “F.Miulli”Regional General HospitalAcquaviva Delle Fonti 70021Italy interventional radiology Unit Department of Radiology“F.Miulli”Regional General HospitalAcquaviva Delle Fonti 75100Italy Hepatobiliary Surgery Division IRCSS San Raffaele Scientific InstituteMilan 20132Italy Hepatobiliary Surgery Division Vita-Salute San Raffaele UniversityMilan 20132Italy Département de Chirurgie Viscérale Gustave Roussy Cancer Campus Grand ParisParis 94800France Unit of Oncologic and Pancreatic Surgery Hospital University Reina SofíaCordoba 14004Spain Department of Digestive and Hepatobiliary Surgery Assistance Publique-Hôpitaux de ParisCréteil 94000France service of Abdominal Surgery Poliambulanza FoundationBrescia 25124Italy Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 41121Italy Department of Surgery Institut de Recherche Contre les Cancers de l'Appareil Digestif(IRCAD)Strasbourg 67000France service de Chirurgie Viscérale et Digestive Nouvel Hôpital CivilUnitéINSERM U1110Strasbourg 67000France Department of Surgery Hôpital Robert DebréReims 51092France Assistance Publique-Hôpitaux de Paris Centre Hospitalier Universitaire Henri MondorParis 94000France Unit of Hepatobiliary Surgery and Liver Transplantation Hospital University Reina SofíaCordoba 14004Spain interventional radiology Unit Niguarda HospitalMilan 20162Italy Department of Surgery Centre HepatobiliaireHopital Paul BrousseParis 94000France

BACKGROUND Liver resection is the mainstay for a curative treatment for patients with resectable hepatocellular carcinoma(HCC),also in elderly *** this,the evaluation of patient condition,liver function and extent of disease remains a demanding process with the aim to reduce postoperative morbidity and *** To identify new perioperative risk factors that could be associated with higher 90-and 180-d mortality in elderly patients eligible for liver resection for HCC considering traditional perioperative risk scores and to develop a risk *** A multicentric,retrospective study was performed by reviewing the medical records of patients aged 70 years or older who electively underwent liver resection for HCC;several independent variables correlated with death from all causes at 90 and 180 d were *** coefficients of Cox regression proportional-hazards model for sixmonth mortality were rounded to the nearest integer to assign risk factors'weights and derive the scoring *** Multivariate analysis found variables(American Society of Anesthesiology score,high rate of comorbidities,Mayo end stage liver disease score and size of biggest lesion)that had independent correlations with increased 90-and 180-d mortality.A clinical risk score was developed with survival *** This score can aid in stratifying this population in order to assess who can benefit from surgical treatment in terms of postoperative mortality.

关键词： Hepatocellular carcinoma Score Laparoscopy Surgical resection Elderly patients Multivariate analysis

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