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Consensus on glycemic management for patients with coronary heart disease and type 2 diabetes

Journal of Geriatric Cardiology 2024年第7期21卷 689-702页

作者： Li-Nong JI Yun-Dai CHEN Jing LIU Xiang-Hai ZHOU Cardiovascular Subcommittee of Chinese international Exchange and Promotion association for Medical and Healthcare Peking University People's Hospital Chinese PLA General Hospital

The prevalence of patients with coronary heart disease(CHD)and diabetes mellitus is notably high,posing sig-nificant residual cardiovascular risks even after routine interventions such as antihypertensive,lipid-lowering,and antithrombot-ic *** studies have demonstrated that certain glucose-lowering medications confer cardiovascular benefits for pa-tients with type 2 ***,a survey indicates that cardiologists may not be fully acquainted with the optimal screen-ing timing,indicators,and diagnostic criteria for type 2 diabetes,and there is insufficient awareness and a low rate of prescrip-tion of novel glucose-lowering medications with proven cardiovascular efficacy,such as glucagon-like peptide-1 receptor agon-ists(GLP-1 RAs)and sodium-glucose co-transporter-2 inhibitors(SGLT-2i).In this context,based on domestic and international guidelines or consensus and the latest evidence-based evidence,this consensus aims to standardize the glycemic management for patients with acute coronary syndrome,chronic coronary syndrome,and perioperative management for percutaneous coronary *** highlights the key points of screening and diagnosis of type 2 diabetes,and the comprehensive management of cardiovascular risk in patients with *** consensus elaborates on the principles and algorithms of glycemic management for CHD patients,without involving acute complications of diabetes,clarifies the clinical practice of glucose-lowering medications with cardiovascular benefits,and promotes the standardized use of these medications in cardiovascular and other related spe-cialty ***,it addresses the glucose-lowering treatment to comprehensively reduce cardiovascular risks.

关键词： coronary patients routine

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Triple signal amplification electrochemical sensing platform for Hg^(2+) in water without direct modification of the working electrode

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 157-167页

作者： Liuyin Hu Jiahua Cui Tao Lu Yalin Wang Jinping Jia School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240China international Copper association Ltd.Shanghai 200020China

An ultrasensitive electrochemical biosensor to detect trace Hg^(2+)in environmental samples was developed utilizing nanogold-decorated magnetic reduced graphene oxide(MrGO-AuNPs),exonuclease III-assisted target cycle(Exo Ⅲ-ATC)and hybridization chain reaction(HCR)synergistic triple signal *** MrGO-AuNPs is a superior carrier for capture DNA(cDNA)and acts as magnetic media for automatic separation and *** innovative utilization of the magnetism and improved sensing efficiency obviates the need for direct modification and repeated polishing of the working ***,the three DNA hairpins(cDNA,methylene blue(MB)labeled HP1 and HP2)further contribute to biosensor specificity and *** cDNA captures Hgt,it activates Exo Ⅲ-ATC due to the formation of a sticky end in the DNA stem via thymine-Hig-thymidine(T-Hg^(2+)-T),this leads to the hydrolysis of self-folded DNA by Exo Ⅲ-ATC to form"key"DNA(kDNA).The kDNA subsequently initiates HCR,resulting in massive super-sandwich structures(kDNA-[HP1/HP2])carrying signaling molecules on MrGO-AuNPs,and this overall structure serves as a signal probe(SP).Leveraging magnetic adsorption,the SP was automatically adsorbed onto the magneto-glass carbon electrode(MGCE),generating an amplified *** biosensor's detection limit(LOD)was 3.14 pmol/L,far below the limit of 10 nmol/L for mercury in drinking water set by the US *** biosensor also showed excellent selectivity when challenged by interfering ions,and the results of its application in actual samples indicate that it has good potential for practical applications in environmental monitoring.

关键词： Electrochemical sensing Hg^(2+) Amplification Graphene Hybridization chain reaction Exonuclease Ⅲ

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Helping Chinese Brands Go Global

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China Today 2024年第7期73卷 60-61页

作者： international COMMUNICATION COMMITTEE OF THE CHINA ADVERTISING association international COMMUNICATION COMMITTEE OF THE CHINA ADVERTISING association

The activity organized by Navigator has enhanced Chinese enterprises’understanding of the strategy of brands going *** is a research institute built by the international Communication Committee(ICC)of the China Advertising association devoted to assisting Chinese brands go *** first activity was held at Huawei's headquarters in Shenzhen,aimed at helping the internationalization of Chinese brands.

关键词： Brand enterprises devoted

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Metallurgical performance evaluation of space-weathered Chang’e-5 lunar soil

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international Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1241-1248页

作者： Chen Li Wenhui Ma Yang Li Kuixian Wei Center for lunar and Planetary Sciences Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming 650093China

Space metallurgy is an interdisciplinary field that combines planetary space science and metallurgical *** involves systematic and theoretical engineering technology for utilizing planetary resources in ***,space metallurgy on the Moon is challenging because the lunar surface has experienced space weathering due to the lack of atmosphere and magnetic field,making the mi-crostructure of lunar soil differ from that of minerals on the *** this study,scanning electron microscopy and transmission electron microscopy analyses were performed on Chang’e-5 powder lunar soil *** microstructural characteristics of the lunar soil may drastically change its metallurgical *** main special structure of lunar soil minerals include the nanophase iron formed by the impact of micrometeorites,the amorphous layer caused by solar wind injection,and radiation tracks modified by high-energy particle rays inside mineral *** nanophase iron presents a wide distribution,which may have a great impact on the electromagnetic prop-erties of lunar *** ions injected by solar wind may promote the hydrogen reduction *** widely distributed amorph-ous layer and impact glass can promote the melting and diffusion process of lunar ***,although high-energy events on the lun-ar surface transform the lunar soil,they also increase the chemical activity of the lunar *** is a property that earth samples and tradi-tional simulated lunar soil *** application of space metallurgy requires comprehensive consideration of the unique physical and chemical properties of lunar soil.

关键词： space metallurgy Chang’e-5 lunar soil space weathering metallurgical performance

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Latest assessment methods for mitochondrial homeostasis in cognitive diseases

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Neural Regeneration Research 2024年第4期19卷 754-768页

作者： Wei You Yue Li Kaixi Liu Xinning Mi Yitong Li Xiangyang Guo Zhengqian Li Department of Anesthesiology Peking University Third Hospital Peking University Third Clinical Medical College Beijing Center of Quality Control and Improvement on Clinical Anesthesia Anesthesia and Perioperative Medicine Branch of China international Exchange and Promotive association for Medical and Health Care(CPAM)

Mitochondria play an essential role in neural function,such as supporting normal energy metabolism,regulating reactive oxygen species,buffering physiological calcium loads,and maintaining the balance of morphology,subcellular distribution,and overall health through mitochondrial *** the recent technological advances in the assessment of mitochondrial structure and functions,mitochondrial dysfunction has been regarded as the early and key pathophysiological mechanism of cognitive disorders such as Alzheimer’s disease,Parkinson’s disease,Huntington’s disease,mild cognitive impairment,and postoperative cognitive *** review will focus on the recent advances in mitochondrial medicine and research methodology in the field of cognitive sciences,from the perspectives of energy metabolism,oxidative stress,calcium homeostasis,and mitochondrial dynamics(including fission-fusion,transport,and mitophagy).

关键词： cognitive disorders mitochondrial dysfunction mitochondrial energy metabolism mitochondrial dynamics mitochondrial transport mitophagy mitochondrial biogenesis oxidative stress calcium homeostasis

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Augmented Appeal China is doubling down on attracting foreign investors through broader market access and improved business environment

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ChinAfrica 2024年第8期16卷 28-30页

作者： WANG XIAOHONG ZHANG JIANPING TANG YIHONG China Centre for international Economic Exchanges China Research association of Social and Economic System School of international Trade and Economics University of International Business and Economics

Attracting foreign capital is a key pillar of China’s reform and opening up policy,and foreign-funded enterprises are an important component of China’s ***,China is taking steps to further boost its attractiveness a... 详细信息

关键词： funded investor attracting

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The Development of Confucianism as a Religion in Indonesia

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走进孔子（中英文） 2024年第1期 114-123页

作者： Chandra Setiawan President University Supervisory Board of the President University Foundation Board of the General Assembly of the international Confucian association

1. Introduction According to Report No. 22, titled“Religion and Its Disciples Throughout the World,” published by the United Nations in 1956, the number of Confucian disciples worldwide reached 300,290,500,ranking fourth after Catholicism, Islam,and Hinduism. Lewis Hodous (1967)stated,“Confucianism was established as the state religion by Emperor Wudi(140-87 BCE) and retained this position till 1912.” Scientific literature indicates that the influence of Confucius’ teachings in Indonesia started at the end of the prehistoric period.

关键词： stated ism Rel

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VLBI with SKA:Possible Arrays and Astrometric Science

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Research in Astronomy and Astrophysics 2024年第7期24卷 1-33页

作者： Yingjie Li Ye Xu Jingjing Li Shuaibo Bian Zehao Lin Chaojie Hao Dejian Liu Purple Mountain observatory Chinese Academy of SciencesNanjing 210023China University of Science and Technology of China Hefei 230026China

The next generation of very long baseline interferometry(VLBI)is stepping into the era of microarcsecond(μas)astronomy,and pushing astronomy,especially astrometry,to new *** with the Square Kilometre Array(SKA),SKA-VLBI,will increase current sensitivity by an order of magnitude,and reach astrometric precision routinely below 10μas,even challenging 1μ*** advancement allows precise parallax and proper motion measurements of various celestial *** improvements can be used to study objects(including isolated objects,and binary or multiple systems)in different stellar stages(such as star formation,main-sequence stars,asymptotic giant branch stars,pulsars,black holes,white dwarfs,etc.),unveil the structure and evolution of complex systems(such as the Milky Way),benchmark the international celestial reference frame,and reveal cosmic ***,the theory of general relativity can also be tested with SKA-VLBI using precise measurements of light deflection under the gravitational fields of different solar system objects and the perihelion precession of solar system objects.

关键词： astrometry-parallaxes-stars kinematics and dynamics-ISM kinematics and dynamics-Galaxy kinematics and dynamics-galaxies kinematics and dynamics-gravitation

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Social prescribing in the metaverse:a new frontier for primary care practice

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Global Health Journal 2024年第1期8卷 32-35页

作者： Arunpirasath Nadarasa international Social Prescribing Pharmacy association Ilford IG1 1YWUnited Kingdom

The advent of immersive technologies such as the metaverse,extended reality,artificial intelligence,and blockchain offers novel possibilities to transform healthcare *** innovations coincide with clinicians'aspirations to deliver more comprehensive,patient-centered care tailored to individuals singular needs and *** of these emerging tools may confer opportunities for providers to engage patients through new modalities and expand their ***,responsible implementation necessitates deliberation of ethical implications and steadfast adherence to foundational principles of compassion and interpersonal connection underpinning the *** the metaverse introduces new channels for social prescribing,this perspective advocates that its ultimate purpose should be strengthening,not supplanting,human *** propose an ethical framework centered on respect for patients'dignity to guide integration of metaverse platforms into medical *** framework serves both to harness their potential benefits and mitigate risks of dehumanization or uncompassionate *** analysis maps the developing topology of metaverse-enabled care while upholding moral imperatives for medicine to promote healing relationships and human flourishing.

关键词： Social prescribing Metaverse Decentralized social prescribing Primarycare

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Cosmology-Independent Photon Mass Limits from Localized Fast Radio Bursts by Using Artificial Neural Networks

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Chinese Physics Letters 2024年第5期41卷 177-183页

作者：冉景遇王宝魏俊杰 Purple Mountain observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Sciences University of Science and Technology of ChinaHefei 230026China

A hypothetical photon mass m_(γ) can produce a frequency-dependent vacuum dispersion of light, which leads to an additional time delay between photons with different frequencies when they propagate through a fixed distance. The dispersion measure and redshift measurements of fast radio bursts(FRBs) have been widely used to constrain the rest mass of the photon. However, all current studies analyzed the effect of the frequency-dependent dispersion for massive photons in the standard ΛCDM cosmological context. In order to alleviate the circularity problem induced by the presumption of a specific cosmological model based on the fundamental postulate of the masslessness of photons, here we employ a new model-independent smoothing technique, artificial neural network(ANN), to reconstruct the Hubble parameter H(z) function from 34 cosmic-chronometer *** combining observations of 32 well-localized FRBs and the H(z) function reconstructed by ANN, we obtain an upper limit of m_(γ) ≤ 3.5 × 10^(-51)kg, or equivalently m_(γ) ≤ 2.0 × 10^(-15)eV/c^(2)(m_(γ) ≤ 6.5 × 10^(-51)kg, or equivalently m_(γ) ≤ 3.6 × 10^(-15)eV/c_(2)) at the 1σ(2σ) confidence level. This is the first cosmology-independent photon mass limit derived from extragalactic sources.

关键词： dispersion limit Independent

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