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中华医学会第七次全国中青年检验医学学术会议

作者： Gary L.Myers international federation for clinical chemistry phd FACB

The role of total cholesterol and lipoproteins in the assessment of cardiovascular disease(CVD) is firmly established from population and intervention *** and low-density lipoprotein cholesterol(LDLC) levels are positively associated with CVD,and high-density lipoprotein cholesterol(HDLC) levels are negatively associated with *** US National Cholesterol Education Program’s Adult Treatment Panel,along with the European Society of Cardiology, identifies elevated LDL cholesterol as the primary target of lipid-lowering therapy for reducing CVD *** the contribution of LDLC to the development of atherosclerosis is well recognized and accepted,evidence suggests it may not be the best circulatory *** to identify

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Adding Value to clinical chemistry and Laboratory Medicine

Adding Value to Clinical Chemistry and Laboratory Medicine

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中华医学会第八次全国检验医学学术会议暨中华医学会检验分会成立30周年庆典大会

作者： Graham H Beastall international federation of clinical chemistry and Laboratory Medicine(IFCC)

Over recent years laboratory medicine specialists have succeeded in improving the quality of practice within the laboratory. Thus internal quality control and external quality assurance are standard while quality management and laboratory accreditation against an international standard(*** 15189) are becoming widely *** the same time the in-vitro diagnostics industry has made improvements to the traceability and quality standards of the products it manufactures and distributes(*** CE mark in the European Union).

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现在与未来的检验医学在医疗卫生中的重要作用

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中华临床实验室管理电子杂志 2013年第1期1卷 2-7页

作者： Graham H Beastall 潘柏申 international federation of clinical chemistry and Laboratory Medicine IFCC Office 20159 Milano Italy 复旦大学附属中山医院检验科

检验医学是医疗卫生中的一项医学专业。医疗卫生的未来发展趋势表明对诊断性检查提供的信息的依赖程度将越来越高,这意味着检验医学的重要作用将得到巩固。检验医学领导者的职责在于从当地医疗卫生环境中发展检验医学的中心地位,进而使... 详细信息

检验医学是医疗卫生中的一项医学专业。医疗卫生的未来发展趋势表明对诊断性检查提供的信息的依赖程度将越来越高,这意味着检验医学的重要作用将得到巩固。检验医学领导者的职责在于从当地医疗卫生环境中发展检验医学的中心地位,进而使患者能最大获益。临床实验室负责人的首要责任是通过国际标准实验室认可(例如ISO 15189)来确保各方面质量的持续改进。在此基础上,地区、国家及国际检验医学领导者需要为检验医学提供增值服务,来确保为患者个人或群体提供最适宜的传递、使用、开发和评估服务。对附加价值的简要诠释的缩写是"SCIENCE",包括7个方面:标准化和一致性(standardisation and harmonisation)、临床效益(clinical effectiveness)、创新(innovation)、循证实践(evidence-based practice)、新项目应用(novel applications)、成本效益(cost effectiveness)和教育培训(education of others)。另一简单方法可用于评估实验室医学的发展,即通过三方面的框架结构(运营效率、患者管理及患者行为)对任何发展进行评估。这2种方法均可使复杂问题转变为简单且可衡量的结果。专业人员和患者则可从良好实践中分享未来检验医学发展的益处。

关键词：增值服务评估值专业管理

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Exhaled volatile organic compounds for cholangiocarcinoma diagnosis

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Liver Research 2022年第3期6卷 191-197页

作者： Nanicha Siriwong Thanikan Sukaram Rossarin Tansawat Terapap Apiparakoon Thodsawit Tiyarattanachai Sanparith Marukatat Rungsun Rerknimitr Roongruedee Chaiteerakij Department of Medicine Faculty of MedicineChulalongkorn UniversityBangkokThailand Division of Gastroenterology Department of MedicineFaculty of MedicineChulalongkorn Universityand King Chulalongkorn Memorial HospitalThai Red Cross SocietyBangkokThailand Department of Food and Pharmaceutical chemistry Faculty of Pharmaceutical SciencesChulalongkorn UniversityBangkokThailand Department of Computer Engineering Faculty of EngineeringChulalongkorn UniversityBangkokThailand clinical Sciences phd international Program Faculty of MedicineChulalongkorn UniversityThailand Image Processing and Understanding Team Artificial Intelligence Research GroupNational Electronics and Computer Technology Center(NECTEC)Thailand Center of Excellence for Innovation and Endoscopy in Gastrointestinal Oncology Chulalongkorn UniversityBangkokThailand

Objectives:The difficulties in the early detection consequent to the lack of sensitive biomarkers render patients with cholangiocarcinoma(CCA)to have poor ***,sensitive and specific volatile organic compounds(VOCs)were identified in several ***,the VOC profiles in CCA are not ***,we investigated the VOC profiles in exhaled breath of CCA patients and ***:We prospectively collected exhaled breath samples from 30 consecutive patients newly diagnosed with CCA and 30 controls who did not have CCA(seven had benign biliary strictures and 23 had other medical conditions).Exhaled VOCs were identified using gas chromatography mass spectrometry Triple Quadrupoles *** of the significant differences in VOCs between cases and controls was conducted using supervised multivariate regression *** validation was performed for these VOCs in another cohort of 18 CCA patients and 22 ***:Levels of six compounds were significantly different between CCA patients and controls,namely,acetone,isopropyl alcohol,dimethyl sulfide,1,4-pentadiene,allyl methyl sulfide,and N,*** and dimethyl sulfide were independently associated with CCA as demonstrated in the multivariate *** the cut-off value of 8.59107 arbitrary unit(AU),acetone had a sensitivity and specificity of 82.1%and 75.8%,respectively,with an area under the receiving operator curve(AUROC)of 0.85 for the CCA *** level was also significantly different between cases and controls in the validation *** the same cut-off value,the sensitivity,specificity,and AUROC was 59.1%,66.7%,and 0.85,***:Breath analysis may potentially be useful for CCA diagnosis.A cohort of patients with earlystage CCA in further studies is needed to confirm the ability of exhaled VOCs for the early detection of CCA.

关键词： Cholangiocarcinoma(CCA) Bile duct cancer Volatile organic compounds(VOCs) Biomarker Cancer screening Diagnostic model

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Fungal diversity notes 1036-1150:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2019年第3期96卷 1-242页

作者： Kevin D.Hyde Danushka S.Tennakoon Rajesh Jeewon DJayarama Bhat Sajeewa S.N.Maharachchikumbura Walter Rossi Marco Leonardi Hyang Burm Lee Hye Yeon Mun Jos Houbraken Thuong T.T.Nguyen Sun Jeong Jeon Jens Christian Frisvad Dhanushka N.Wanasinghe Robert Lucking Andre Aptroot Marcela E.S.Caceres Samantha C.Karunarathna Sinang Hongsanan Rungtiwa Phookamsak Nimali Ide Silva Kasun M.Thambugala Ruvishika S.Jayawardena Indunil C.Senanayake Saranyaphat Boonmee Jie Chen Zong-Long Luo Chayanard Phukhamsakda Olinto L.Pereira Vanessa P.Abreu Andre Wilson Campos Rosado Buyck Bart Emile Randrianjohany Vale rie Hofstetter Tatiana B.Gibertoni Adriene Mayrada Silva Soares Helio Longoni Plautz Jr Helen Maria Pontes Sotao William Kalhy Silva Xavier Jadson Diogo Pereira Bezerra Thays Gabrielle Linsde Oliveira Cristina Mariade Souza-Motta Oliane Maria Correia Magalhaes Digvijayini Bundhun Dulanjalee Harishchandra Ishara S.Manawasinghe Wei Dong Sheng-Nan Zhang Dan-Feng Bao Milan C.Samarakoon Dhandevi Pem Anuruddha Karunarathna Chuan-Gen Lin Jing Yang Rekhani H.Perera Vinit Kumar Shi-Ke Huang Monika C.Dayarathne Anusha H.Ekanayaka Subashini C.Jayasiri Yuanpin Xiao Sirinapa Konta Tuula Niskanen Kare Liimatainen Yu-Cheng Dai Xiao-Hong Ji Xue-Mei Tian Armin Mesic Sanjay K.Singh Kunthida Phutthacharoen Lei Cai Touny Sorvongxay Vinodhini Thiyagaraja Chada Norphanphoun Napalai Chaiwan Yong-Zhong Lu Hong-Bo Jiang Jin-Feng Zhang Pranami D.Abeywickrama Janith V.S.Aluthmuhandiram Rashika S.Brahmanage Ming Zeng Thilini Chethana Deping Wei Martina Reblova Jacques Fournier Jana Nekvindova Renan do Nascimento Barbosa Jose Ewerton Felintodos Santos Neiva Tintide Oliveira Guo-Jie Li Damien Ertz Qiu-Ju Shang Alan J.L.Phillips Chang-Hsin Kuo Erio Camporesi Timur S.Bulgakov Saisamorn Lumyong E.B.Gareth Jones Putarak Chomnunti Eleni Gentekaki Frank Bungartz Xiang-Yu Zeng Sally Fryar Zdenko Tkalcec Junmin Liang Guangshuo Li Ting-Chi Wen Paras Nath Singh Yusufjon Gafforov Itthayakorn Promputtha Erandi Yasanthika Ishani D.Goonasekara Rui-Lin Zhao Qi Zhao Paul M Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand East and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanPeople’s Republic of China Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Department of Plant Medicine National Chiayi University300 Syuefu RoadChiayi City 60004TaiwanPeople’s Republic of China Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Formerly Department of Botany Goa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaGoa Velha 403108India Department of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityPO Box 8123 Al KhoudOman Sect.Environmental Sciences Dept.MeSVAUniversity of L’Aquila67100 CoppitoAQItaly Division of Food Technology Biotechnology&AgrochemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186Korea Fungal Resources Research Division NNIBRSangju-si 37242Korea Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands Department of Biotechnology and Biomedicine DTUBioengineeringTechnical University of Denmark2800 Kongens LyngbyDenmark Botanischer Garten und Botanisches Museum Berlin Freie Universitat BerlinKonigin-Luise-StraßBe 6-814195 BerlinGermany Laboratorio de Botanica/Liquenologia Instituto de BiocienciasUniversidade Federal de Mato Grosso do SulAvenida Costa e Silva s/nBairro UniversitarioCampo GrandeMatto Grosso do Sul CEP 79070-900Brazil Departamento de Biociencias Universidade Federal de SergipeItabaianaSergipe CEP:49500-000Brazil Shenzhen Key Laboratory of Microbial

This article is the tenth series of the Fungal Diversity Notes,where 114 taxa distributed in three phyla,ten classes,30 orders and 53 families are described and *** described in the present study include one new family(*** in Dothideomycetes),five new genera(Caatingomyces,Cryptoschizotrema,Neoacladium,Paramassaria and Trochilispora)and 71 new species,(*** thailandica,Amniculicola aquatica,***,Angustimassarina sylvatica,Blackwellomyces lateris,Boubovia gelatinosa,Buellia viridula,Caatingomyces brasiliensis,Calophoma humuli,Camarosporidiella mori,Canalisporium dehongense,Cantharellus brunneopallidus,***,Castanediella meliponae,Coprinopsis psammophila,Cordyceps succavus,Cortinarius minusculus,***,Diaporthe italiana,***,Diatrypella delonicis,Dictyocheirospora aquadulcis,***,Digitodesmium chiangmaiense,Distoseptispora dehongensis,***,Dothiorella styphnolobii,Ellisembia aurea,Falciformispora aquatic,Fomitiporia carpinea,***,Grammothele aurantiaca,***,Hermatomyces bauhiniae,Jahnula queenslandica,Kamalomyces mangrovei,Lecidella yunnanensis,Micarea squamulosa,Muriphaeosphaeria angustifoliae,Neoacladium indicum,Neodidymelliopsis sambuci,Neosetophoma miscanthi,***,Nodulosphaeria aquilegiae,***,Paramassaria samaneae,Penicillium circulare,***,***-pumilae,***,***,Phaeoisaria siamensis,Phaeopoacea asparagicola,Phaeosphaeria penniseti,Plectocarpon galapagoense,Porina sorediata,Pseudoberkleasmium chiangmaiense,Pyrenochaetopsis sinensis,Rhizophydium koreanum,Russula prasina,Sporoschisma chiangraiense,Stigmatomyces chamaemyiae,***,***,***,***,Thysanorea uniseptata,Torula breviconidiophora,***,Trochilispora schefflerae and Vaginatispora palmae).Further,twelve new combinations(*** cryptotrema,Prolixandromyces australi,***,***,***,P.

关键词： 71 new taxa Ascomycota Basidiomycota Dothideomycetes Eurotiomycetes Lecanoromycetes Leotiomycetes Pezizomycetes Phylogeny Taxonomy

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