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国际脑血管病杂志 2016年第6期24卷 481-496页

作者： Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师张劼陈涵丰俞娅美徐子奇罗本燕 department of Neurology University of New Mexico Albuquerque New Mexico USA Institute of Neuroscience and Physiology Sahlgrenska Academy Gothenburg University Gothenburg Sweden Centre for Clinical Brain Sciences University of Edinburgh Edinburgh UK department of Clinical Neurosciences University of Cambridge Cambridge UK Neurovascular Research Laboratory Vail d'Hebron Research Institute Universitat Auto'noma de Barcelona Barcelona Spain department of Neurology University of Connecticut Health Center Farmington Connecticut USA Feil Family Brain and Mind Research Institute Weill Cornell Medical College New York New York USA department of Physiology and Biophysics Zilkha Neurogenetic Institute Keck School of Medicine University of Southern Califomia Los Angeles California USA INSERM U1161 Paris France Institute for Stroke and dementia Research Klinikum der Universitat Mtinchen Munich Germany department of Neurology Medical University of Graz Graz Austria Tel-Aviv University Medical School Ramat Aviv Israel department of Neurology Memory and Aging Center and Department of Pathology University of Califomia San Francisco California USA University of sao paulo Medical School Sao Paulo Brazil department of Neurology University of Southern California Medical School Los Angeles California USA department of Clinical Neurological Sciences University Hospital University of Western Ontario London Ontario Canada 浙江大学医学院附属第一医院杭州310003

血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病（Binswanger＇s disease, BD）的进行性白质损害患者构成了从单纯血管性... 详细信息

血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病（Binswanger＇s disease, BD）的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组，存在缺氧缺血、腔隙性梗死和炎症，它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物，这将有助于诊断以及将来协作性治疗试验的患者选择。

关键词：宾斯旺格病血脑屏障通透性脑脊液炎症白质疏松

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Helicobacter pylori and its reservoirs:A correlation with the gastric infection

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2016年第1期7卷 126-132页

作者： Spencer Luiz Marques Payao Lucas Trevizani Rasmussen Laboratório de Genética Hemocentro Marília Medical School FAMEMA department of Graduate-Level Research Sacred Heart University Universidade do Sagrado Coracao

Helicobacter pylori(H. pylori) has long been found to cause gastric diseases such as gastritis, gastric ulcers and gastric cancer. The transmission medium of this bacterium has yet to be determined, though several studies have speculated that the oral cavity is a reservoir for H. pylori. Others have also reported that the oral cavity may be a source of both transmission and gastric reinfection; however, such results are controversial. We reviewed the literature and selected studies that report an association among H. pylori detections in the oral cavity(dental plaque, saliva, tongue, tonsil tissue, root canals, oral mucosa) in humans and in animals, as well as in the human stomach. The oral cavity may be considered the main reservoir for H. pylori. There are a correlations between H. pylori infection in the oral cavity and periodontal disease, oral tissue inflammation, H. pylori transmission, and gastric reinfection. We believe that the mouth is a reservoir and that it plays a crucial role in both H. pylori transmission and gastric infection.

关键词： Helicobacter pylori Reservoirs Oral cavity Infection Gastric disease

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Strategic Planning as a Competitive Advantage by Using the BSC as a Management Tool： A Case Study in Application of Radioisotope Technology at IPEN

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Journal of Physical Science and Application 2016年第3期6卷 1-10页

作者： Imario Vieira Fernando Codelo Nascimento Wilson Aparecido Parejo Calvo National Service for Industrial Apprenticeship (SENA1) SENAI Mario Amato School Av. Vit6ria Maria Mddici Ramos 33009861-000 S6o Bernardo do Campo/SP Brazil Nuclear and Energy Research Institute (IPEN) National Nuclear Energy Commission (CNEN) Av. Professor Lineu Prestes 224205508-000 S6o Paulo/SP Brazil

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