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未来食品学报(英文) 2024年第1期4卷 83-90页

作者： Yun Xie Xuemei Nie Chang Wang Xiuli Xu Feng Zhang institute of Food Safety Chinese Academy of Inspection and QuarantineBeijing 100176China Key Laboratory of Food Quality and Safety for State Market Regulation Chinese Academy of Inspection&QuarantineBeijing 100176China

Due to the lack of effective assessment method,overheated milk commodities are often marketed as pasteurized milk on the market,which was sold in high price by ***,this article aims to establish an approach based on metabolomics to monitor thermal processing temperature of bovine *** data of bovine milk samples heated at temperatures ranging from 60℃to 150℃were achieved by ultra-performance liquid chromatography-high-resolution mass spectrometry(UPLC-HRMS)platform,followed by multivariate data analysis.A regular variation pattern of chemical composition as temperature rises was pictured,furthermore.N^(∈)carboxymethyl lysine(CML),N^(∈)-carboxyethyl lysine(CEL),*** and lysinoalanine(LAL)were identified as 5 of the most contributed compounds to discriminate pasteurized and ultra-high-temperature(UHT)*** the comprehensive study on their content changes,we concluded that the optimal temperature range was 90-100℃for the generation of CML and CEL in this experiment,moreover.110~120℃for LAL.S0~100℃for pentosidine and 130-140℃for ***,a predicted rule to discriminate pasteurized and UHT milk was preliminarily established based on the ratios of CML/***/pentosidine and CML/*** could be applied in food labelling authentication of commercial bovine milk after further validation.

关键词： Metabolomics Heat treatment Bovine milk Pasteurization Utra-high-temperature

Recent advances in magnetic molecularly imprinted polymers and their application in the food safety analysis

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未来食品学报(英文) 2024年第1期4卷 1-20页

作者： Beibei Jia Feng Feng Xiujuan Wang Yaxuan Song Feng Zhang institute of Food Safety Chinese Academy of Inspection and QuarantineBeijing 100176China Key Laboratory of Food Quality and Safety for State Market Regulation Beijing 100176China

Food safety is a worldwide concern and is directly related to human ***,convenient,effective,and economical methods and technologies for food safety analysis have been developed *** molecularly imprinted polymers(MMIPs)have gained extensive attention in recent years,as they have high selectivity,high adsorption capacity,and are easy to isolate from food ***,advanced strategies for the synthesis of MMIPs have been proposed to solve problems of template leakage and non-specific adsorption,and to increase the biocompatibility,adsorption rate,as well as adsorption capacity of the imprinted *** this review,we focus on new attempts at modification of magnetic core and MMIPs’surfaces,and the selection of template,functional monomer,cross-linker as well as *** are summarized that used advanced MMIPs for the recognition and adsorption of pesticide residues,veterinary drug residues,mycotoxins,contaminants,and adulterations in foodstuffs over the last 5 ***,some still existing challenges and future prospects to further promote MMIPs properties are also discussed.

关键词： Food safety Magnetic molecularly imprinted polymers Pesticide residues Mycotoxins Contaminants

Minerals in edible insects:a review of content and potential for sustainable sourcing

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Food Science and Human Wellness 2024年第1期13卷 65-74页

作者： Mingxing Lu Chenxu Zhu Sergiy Smetana Ming Zhao Haibo Zhang Fang Zhang Yuzhou Du College of plant Protection&institute of Applied Entomology Yangzhou UniversityYangzhou 225009China German institute of Food Technologies(DIL e.V.) Quakenbrück D-49610Germany Jiangsu plant Protection and plant quarantine Station Nanjing 210036China Joint International Research Laboratory of Agriculture and Agri-Product Safety Yangzhou UniversityYangzhou 225009China

In response to the rapid increase in world population and subsequent demands for food,edible insects represent an alternative food source for humans that is rich in proteins,amino acids and *** is a tradition in many countries including China and Thailand,and edible insects have attracted a lot of attention in Western World due to their suitable nutrient composition,high mineral content(e.g.,Fe,Zn,Ca,Mg)and potential use as a supplement in human *** this study,we surveyed mineral content in seven insect orders and 67 species of mass produced and wild-harvested edible *** total content of essential elements in edible insects was very high in Tenebrio molitor,Bombyx mori,and Zonocerus *** heavy metal content(summarized for eight species)was below the maximum limit allowed for safe *** supply of minerals derived from insect biomass is complicated due to the high variations of mineral content in insects and the potential of its change due to processing.

关键词： Edible insects Minerals Nutrition Food safety Sustainability

Phenylalanine deprivation inhibits multiple myeloma progression by perturbing endoplasmic reticulum homeostasis

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3493-3512页

作者： Longhao Cheng Xiaoxue Wang Aijun Liu Ying Zhu Hu Cheng Jiangling Yu Lili Gong Honglin Liu Guolin Shen Lihong Liu institute of Clinical Medical Sciences ChinaeJapan Friendship HospitalCapital Medical UniversityBeijing 100029China Department of Pharmacy ChinaeJapan Friendship HospitalBeijing 100029China Beijing Chao-Yang Hospital Capital Medical UniversityBeijing 100020China institute of Chemicals Safety Chinese Academy of Inspection and QuarantineBeijing 100020China

Amino acid metabolic remodeling is a hallmark of cancer,driving an increased nutritional demand for amino *** acids are pivotal for energetic regulation,biosynthetic support,and homeostatic maintenance to stimulate cancer ***,the role of phenylalanine in multiple myeloma(MM)remains ***,we demonstrate that phenylalanine levels in MM patients are decreased in plasma but elevated in bone marrow(BM)*** the treatment,phenylalanine levels increase in plasma and decrease in *** suggests that changes in phenylalanine have diagnostic value and that phenylalanine in the BM microenvironment is an essential source of nutrients for MM *** requirement for phenylalanine by MM cells exhibits a similar *** phenylalanine utilization suppresses MM cell growth and provides a synergistic effect with Bortezomib(BTZ)treatment in vitro and murine ***,phenylalanine deprivation induces excessive endoplasmic reticulum stress and leads to MM cell apoptosis through the ATF3eCHOPeDR5 *** with ATF3 significantly affects phenylalanine deprivation *** conclusion,we have identified phenylalanine metabolism as a characteristic feature of MM metabolic *** is necessary for MM proliferation,and its aberrant demand highlights the importance of lowphenylalanine diets as an adjuvant treatment for MM.

关键词： Multiple myeloma Phenylalanine Amino acid metabolism Nutrient deprivation Cancer therapy Endoplasmic reticulum stress ATF3 Apoptosis

Cytospora pyri promotes Erwinia amylovora virulence by providing metabolites and hyphae

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Journal of Integrative Agriculture 2024年第9期23卷 3045-3054页

作者： Tong Shen Mengdi Ye Yeping Xu Bohan Ding Hongtao Li Li Zhang Jun Wang Yanli Tian Baishi Hu Youfu Zhao College of plant Protection/Key Laboratory of Integrated Management of Crop Diseases and Pests Nanjing Agricultural UniversityNanjing 210095China Key Laboratory of plant quarantine Pests Monitoring and Control Ministry of Agriculture and Rural AffairsNanjing 210095China plant Protection and quarantine Station of Xinjiang Uygur Autonomous Region Urumqi 830001China Xinjiang Key Laboratory of Agricultural Biosafety Institute of Plant ProtectionXinjiang Academy of Agricultural SciencesUrumqi 830013China College of Agriculture Xinjiang Agricultural UniversityUrumqi 830052China plant Pathology Department Washington State UniversityProsserWA 24106USA

Bacterial-fungal interactions are widespread in *** observed that pear orchards affected by Cytospora pyri(formerly Valsa pyri)were often accompanied with Erwinia ***,the relationship of the two pathogens was *** objective of this study was to determine whether the synergistic effect exists between *** and *** first analyzed the coexistence frequencies of *** and *** in pear *** of the two pathogens,growth,physical interactions,amylovoran production,and expression of genes for amylovoran biosynthesis were *** results showed that *** and *** could coexist on the same lesion and caused much more severe *** also found that *** could physically attach to *** and the expression of amylovoran biosynthesis genes were up-regulated with fungal metabolite *** results indicate that *** and *** can cooperatively interact,which provides *** with an opportunity to promote bacterial dispersal and production of virulence factor in ***.

关键词： pear fire blight Erwinia amylovora Valsa canker amylovoran synergy

Colorimetric Detection of Acid Phosphatase and Malathion Using NiCo_(2)O_(4)Nanosheets as Peroxidase-Mimicking Activity

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Journal of Analysis and Testing 2024年第2期8卷 170-179页

作者： Jia Chen Zerong Long Yan Li Hongdeng Qiu Xinjiang Uygur Autonomous Product Quality Supervision and inspection institute Urumqi830000China CAS Key Laboratory of Chemistry of Northwestern plant Resources and Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China

The establishment of a low-cost and facile approach for the assay of acid phosphatase(ACP)and its inhibitor is a research *** this paper,we successfully synthesized NiCo_(2)O_(4)nanosheets with peroxidase-mimicking activity in alkaline deep eutectic solvents(DESs)composed of NaOH and PEG-200,which can catalyze 3,3',5,5'-tetramethylbenzidine(TMB)to the oxidation state TMB(ox-TMB)in the presence of *** to L-ascorbic acid-2-phosphate can be hydrolyzed into ascorbic acid by ACP,the peroxidase-like activity of NiCo_(2)O_(4)nanosheets is ***,the addition of malathion,an inhibitor of ACP,can inhibit the activity of ACP and thus limit the production of ascorbic acid(AA).Therefore,a colorimetric approach can be established for highly sensitive and selective detection of ACP and malathion with detection limits of 0.032 U/L and 0.65 nmol/L,*** importantly,this method can be successfully applied to malathion detection in environmental samples tap water and food cucumber juice,indicating that it has potential application prospects in environmental and agricultural fields.

关键词： NiCo_(2)O_(4)nanosheets Acid phosphatase Malathion Peroxidase-mimicking activity Colorimetric

One new species in the genus Elaphropeza(Diptera:Empididae)from Chongqing,China

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Entomotaxonomia 2024年第3期46卷 241-244页

作者： Renhui WU Chunmin ZHANG Naizhong CHEN Ding YANG Department of Entomology College of Plant ProtectionChina Agricultural UniversityBeijing 100193China Tongliao plant Protection and quarantine Center TongliaoInner Mongolia 028000China Chinese Academy of inspection and quarantine Beijing 100123China

Elaphropeza is distributed worldwide with over 220 known species,of which 61 species were known to occur in *** species of Elaphropeza are reported from Chongqing for the first *** species,Elaphropeza chongqingana ***... 详细信息

关键词： dance fly taxonomy key

Interaction Between Ustilaginoidea virens and Rice and Its Sustainable Control

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Rice science 2024年第3期31卷 269-284页

作者： ZHANG Fengmin CAO Zhenzhen ZHENG Xin HE Yuntao CHEN Mingxue LIN Xiaoyan Rice Product Quality inspection&Supervision Testing Center of Ministry of Agriculture and Rural Affairs China National Rice Research InstituteHangzhou 310006China

Ustilaginoidea virens is a common rice pathogen that can easily lead to a decline in rice quality and the production of toxins pose potential risks to human *** this review,we present a comprehensive literature review of research since the discovery of rice false *** provide a comprehensive and,at times,critical overview of the main results and findings from related research,and propose future research ***,we delve into the interaction between *** and rice,including the regulation of transcription factors,the process of *** infecting rice panicles,and the plant immune response caused by rice *** that,we discuss the identification and characterization of mycotoxins produced by the pathogenic fungus,as well as strategies for disease *** emphasize the importance of comprehensive agricultural prevention and control methods for the sustainable management of *** knowledge will update our understanding of the interaction between *** and rice plants,offering a valuable perspective for those interested in ***.

关键词： rice false smut flower-specific infection mycotoxin food safety plant disease

Colorimetric detection of α-glucosidase activity using Ni-CeO_(2)nanorods and its application to potential natural inhibitor screening

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Chinese Chemical Letters 2024年第9期35卷 387-391页

作者： Jia Chen Yun Liu Zerong Long Yan Li Hongdeng Qiu Xinjiang Uygur Autonomous Product Quality Supervision and inspection institute Urumqi 830000China CAS Key Laboratory of Chemistry of Northwestern plant Resources and Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China

In this work,we established an exceptionally facile method for the preparation of Ni-CeO_(2)nanorods in a kind of deep eutectic solvents(DESs)composed of l-proline and Ce(NO_(3))_(3)·6H_(2)***,Ni-CeO_(2)nanorods were successfully prepared by adding Ni(NO_(3))_(3)·6H_(2)O to ***,we found that Ni-CeO_(2)nanorods prepared in DESs have more prominent oxidase-like activity than pure CeO_(2).The outstanding catalytic activity of Ni-CeO_(2)could be ascribed to its high Ce^(3+)/Ce^(4+)*** a proof-of-concept application,the Ni-CeO_(2)nanorods were successfully acted as a colorimetric platform for the sensitive determination of ascorbic acid andα-glucosidase activity,which displays excellent analytical ***,this sensing platform was applied for screening naturalα-glucosidase inhibitors,such as terpenoids from natural *** results indicated that ursolic acid and oleanolic acid had good inhibitory *** strategy not only provides a new way to construct more kinds of nanomaterials from DESs,but also offers a facile and effective tool to screen theα-glucosidase natural inhibitors as potential anti-diabetic drugs.

关键词： Ni-CeO_(2) Ascorbic acid α-Glucosidase Inhibitor screening Nanozyme

Management of Colorado potato beetle in invasive frontier areas

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Journal of Integrative Agriculture 2020年第2期19卷 360-366页

作者： WANG Cong XU Han PAN Xu-bin institute of plant quarantine Chinese Academy of Inspection and Quarantine

Colorado potato beetle(CPB)is one of the most devastating invasive insects and it is native to North *** feeds on several wild species of the genus Solamum,such as *** and *** Dunal,and is one of the major pests of potato and *** in the early 19 th century,CPB has rapidly spread across North America,Europe,and Central *** was first reported to invade Xinjiang of China in 1993 and it was effectively controlled in Mori *** 2013,CPB has also been found in Jilin and Heilongjiang in Northeast China,and it likely migrated to these provinces from ***,China has become the frontier for the global CPB spread,and risk management and monitoring systems for this pest are urgently ***,we summarize pest management methods that are used in areas at the frontier of the CPB invasion,and put forward frameworks for further preventing and controlling of the spread of *** management methods for CPB can also serve as an example for the control of invasive species mitigation in frontier areas.

关键词： potential geographical distribution monitoring strategies host management