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Uptake of HIV Self-testing among Men Who have Sex with Men in Beijing, China： a Cross-sectional Study

Biomedical and Environmental Sciences 2017年第6期30卷 407-417页

作者： REN Xian Long WU Zun You MI Guo Dong MCGOOGAN Jennifer ROU Ke Ming ZHAO Yan Division of prevention Intervention National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China National Center for aids/std control and prevention Chinese Center for Disease Control and Prevention Beijing 102206 China Office of the Director National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China Division of Treatment and Care National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China

Objective To examine HIV self-testing uptake and its determinates among men who have sex with men （MSM） in Beijing, China. Methods A cross-sectional online survey was conducted in Beijing, China in 2016. Participants were users of a popular Chinese gay networking application and had an unknown or negative HIV status. Univariate and multivariate logistic regression analyses were conducted to examine factors associated with HIV self-testing based on adjusted odds ratio （AOR） and 95% confidence interval （CI）. Results Among the 5,996 MSM included in the study, 2,383 （39.7%） reported to have used HIV self-testing kits. Willingness to use an HIV self-test kit in the future was expressed by 92% of the participants. High monthly income （AOR = 1.49; CI = 1.10-2.02; P = 0.010）, large number of male sex partners （≥2： AOR = 1.24; CI = 2.09-1.43; P = 0.002）, sexual activity with commercial male sex partners （〉 2： AOR = 1.94; CI = 1.34 -2.82; P = 0.001）, long-term drug use （AOR = 1.42; CI = 1.23-1.62; P 〈 0.001）, and long-term HIV voluntary counseling and testing （VCT） attendance （AOR = 3.62; CI = 3.11-4.22; P 〈 0.001） were all associated with increased odds of HIV self-testing uptake. Conclusion The nearly 40% rate of HIV self-testing uptake among MSM in our sample was high. In addition, an over 90% willingness to use kits in the future was encouraging. HIV self-testing could be an important solution to help China achieve the global target of having 90% of all people living with HIV diagnosed by 2020.

关键词： Men who have sex with men HIV self-testing Associated factors Beijing

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Changing Mortality and Patterns of Death Causes in HIV Infected Patients—China,2013-2022

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China CDC weekly 2023年第48期5卷 1073-1078页

作者： Yan Zhao Lai Wei Zhihui Dou Decai Zhao Xiumin Gan Yasong Wu Mengjie Han National Center for aids/std control and prevention Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?The advent of antiretroviral therapy(ART)has markedly decreased mortality rates among patients infected with human immunodeficiency virus(HIV).Globally,there has been a 43%reduction in acquired immunodeficiency syndrome(aids)-related deaths from 2010 to ***,prior research indicates that the initiation of ART at an early stage within China has substantially lowered mortality *** is added by this report?Over the previous decade,following the implementation of China’s universal ART access strategy,the patterns of mortality causes among HIVinfected individuals across the country have undergone significant *** 2022,the all-cause mortality rate among this population was reported at 2.7%,with the non-aids-related mortality rate at 1.8%.However,it is important to consider that the accuracy of death reporting could contribute to potential misclassification of the underlying causes of *** are the implications for public health practice?Efforts to enhance health outcomes should persist in emphasizing the advancement of ART strategies,with a particular focus on mitigating non-aids-related mortality in the future.

关键词： markedly alterations Pattern

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Characteristics of Long-term Nonprogressors and Viremia controllers Infected with HIV-1 via Contaminated Blood Donations or Transfusions Conducted 20 Years Earlier

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Biomedical and Environmental Sciences 2017年第12期30卷 907-912页

作者： LIU Jia FAN Pan Ying XUE Xiu Juan YAN Jiang Zhou SUN Guo Qing LIU Chun Hua TIAN Sui An LI Ning SUN Ding Yong ZHU Qian WANG Zhe institute for prevention and control of aids and std Henan Center for Disease Control and PreventionZhengzhou 450016HenanChina

To characterize long-term nonprogressors （LTNPs） and viremia controllers （VCs）, infected with HIV-1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan, China. LTNPs and VCs were defined by CD4＋T lymphocyte （CD4） count and viral load （VL）. Of 29,294 patients infected with HIV-1 via contaminated blood donation or transfusion that had conducted for more than 20 years, 92 were LTNPs/VCs. There were 70 LTNPs （0.24%）, 43 VCs （0.15%）, and 48 LTNPs＋VCs- （0.16%）.

关键词： Characteristics of Long-term Nonprogressors HIV-1 v/a Contaminated Blood Donations

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Temporal and Spatial Trends in HIV Positivity Rate for VCT Clinics—China,2015–2022

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China CDC weekly 2024年第1期6卷 6-11页

作者： Yi Liu Rong Su Dongmin Li Shaorong Wang Mengjie Han National Center for aids/std control and prevention Chinese Center for Disease Control and PreventionBeijingChina

Introduction:Human immunodeficiency virus(HIV)voluntary counseling and testing(VCT)clinics play a critical role in identifying and diagnosing HIV *** study aimed to describe the trend of HIV positivity rate(HPR)among Chinese VCT clinics between 2015 and ***:This study utilized data from the China Information System for Disease control and prevention to analyze the trend in the HPR for VCT clinics from 2015 to *** HPR was calculated by dividing the number of newly-reported HIV cases by the number of HIV tests,multiplied by 100%.To identify temporal and spatial trends in the HPR,we employed joinpoint regression analysis and the Getis-Ord hotspot ***:From 2015 to 2022,VCT clinics in China performed a total of 22,075,386 HIV tests,leading to the identification of 260,353 HIV cases,resulting in a HPR of 1.18%.The HPR consistently declined over the study period,with an average annual percent change(AAPC)of−7.5%(95%confidence interval:−12.6%,−2.2%,P<0.05).The number of HPR hotspots also decreased from 41 in 2015 to 23 in *** HPR hotspots were primarily located in Yunnan,Sichuan,Guangdong,and Guangxi provincial-level administrative divisions(PLADs).Among the 31 PLADs,16 showed a significant decrease in HPR during the study period(AAPC<0,PAAPC<0.05).Conclusions:VCT clinics in China have played a significant role in identifying HIV *** declining HPR observed in these clinics may indicates the progress has been made in some degree in mitigating HIV among high-risk ***,it is crucial to further improving the utilization of VCT clinics for HIV testing.

关键词： VCT dividing Spatial

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Characteristics of the HIV/aids Epidemic among People Aged≥50 Years in China during 2018–2021

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Biomedical and Environmental Sciences 2024年第4期37卷 399-405页

作者： HOU Yu Shan JIN Yi Chen CAI Chang TANG Hou Lin QIN Qian Qian LYU Fan National Center for aids/std control and prevention Chinese Center for Disease Control and PreventionBeijing 102206China

Objective This study aimed to determine the current epidemiological status of PLWHA aged≥50 years in China from 2018 to *** also aimed to recommend targeted interventions for the prevention and treatment of HIV/aids in elderly *** Data on newly reported cases of PLWHA,aged≥50 years in China from 2018 to 2021,were collected using the *** tests and spatial analyses were also *** Between 2018 and 2021,237,724 HIV/aids cases were reported among patients aged≥50 years in *** main transmission route was heterosexual transmission(91.24%).Commercial heterosexual transmission(CHC)was the primary mode of transmission among males,while non-marital non-CHC([NMNCHC];60.59%)was the prevalent route in *** proportion of patients with CHC decreased over time(Z=67.716,Paids cases exhibited spatial *** on these results,the expansion of HIV testing,treatment,and integrated behavioral interventions in high-risk populations is recommended to enhance disease detection in key regions.

关键词： HIV/aids Aged≥50 years China

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Psychoactive Substance Use and the Impact on the aids Epidemic Among the MSM Population:a Meta-Analysis—Worldwide,2014-2023

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China CDC weekly 2024年第42期6卷 1086-1092,I0001-I0006页

作者： Donghang Luo Jie Xu Wei Luo National Center for aids/std control&prevention Chinese Center for Diseases Control and PreventionBeijingChina

What is already known about this topic?There is a correlation between psychoactive substance use and heightened human immunodeficiency virus(HIV)susceptibility in men who have sex with men(MSM)populations,although the precise impact on transmission risk remains *** is added by this report?In MSM populations,rush poppers and amphetamines are widely used,with rates of 10.91%and 9.97%.In China,rush poppers usage is notably higher at 47.26%.For other regions and coutries,amphetamines(12.86%),rush poppers(3.62%),and GHB(3.34%)are most ***,17%of MSM use psychoactive substances,with higher HIV risk from amphetamines[Odds ratio(OR)3.06]compared to rush poppers(OR 1.51)and general substances(OR 1.76).What are the implications for public health practice?This study supports the idea that targeting specific regions and types of psychoactive substances for reduction among MSM populations can help decrease HIV transmission as well as promote prevention strategies.

关键词： prevention precise Impact

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Comparative Analysis of Epidemiological Features of HIV/aids Cases Aged Over and Under 50 Years Old—China,2010-2022

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China CDC weekly 2023年第48期5卷 1079-1083页

作者： Yushan Hou Yichen Jin Chang Cai Qianqian Qin Houlin Tang Fan Lyu National Center for aids/std control and prevention Chinese Center for Disease Control and PreventionBeijingChina

Introduction:Recent data indicate a year-on-year increase in the proportion of human immunodeficiency virus/acquired immunodeficiency syndrome(HIV/aids)cases reported among individuals aged≥50 in *** study compares the epidemiological characteristics of HIV/aids cases in populations above and below 50 years of *** doing so,it seeks to scrutinize the current epidemiological landscape of HIV within these distinct age cohorts and suggest tailored interventions for each ***:We utilized data from the Chinese HIV/aids Comprehensive Response Information Management System for our comparative *** regression analysis was employed to assess the trends in standardized detection ***:In China,the number of newly reported HIV/aids cases in the 15-49 age group increased from 51,436 in 2010 to 55,397 in 2022,while it increased from 11,751 in 2010 to 51,856 in 2022 in the group aged≥50 *** years have seen a greater proportion and detection rate of HIV/aids cases among the≥50 age demographic compared to the 15-49 age *** 2022,significant statistical differences were observed between males and females in both age cohorts with respect to education,marital status,occupation,mode of transmission,location of diagnosis,and ***:The observed trend of a rising proportion of HIV/aids cases in individuals aged 50 years and older necessitates heightened *** is imperative that we develop and implement interventions specifically designed to prevent and control the transmission of HIV within this demographic.

关键词： HIV/aids diagnosis analysis

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HIV Infection and Associated Factors Among Out-of-School MSM Aged 16–24 Years—6 Cities and Tianjin Municipality,China,2022–2023

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China CDC weekly 2024年第3期6卷 45-50页

作者： Hui Liu Qiyu Zhu Lei Zhang Yujing Liu Peng Xu Mengjie Han National Center for aids/std control and prevention Chinese Center for Disease Control and PreventionBeijingChina Chinese Association of std and aids prevention and control BeijingChina Beijing Chaoyang Kangzhong Health and Education Center BeijingChina

What is already known about this topic?Approximately 80%of newly diagnosed human immunodeficiency virus(HIV)cases among individuals aged 15–24 years in China are attributed to out-ofschool *** is added by this report?This study presents findings on HIV prevalence and comprehensive insights into HIV service utilization,risky behaviors,and prevention knowledge among young out-of-school men who have sex with men(MSM)aged 16–24 years in *** population exhibits a disproportionately high burden of HIV,with only 51.6%of HIV cases previously *** are the implications for public health practice?HIV services should be expanded to include these key *** interventions are needed to remove barriers to regular HIV services faced by young key populations.

关键词： prevention remove expanded

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Epidemiological Analysis on Reported Hepatitis C Cases in China from 2012 to 2016

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Biomedical and Environmental Sciences 2018年第10期31卷 773-776页

作者： HEI Fa Xin YE Shao Dong DING Guo Wei PANG Lin WANG Xiao Chun LIU Zhong Fu National Center for aids/std control and prevention Chinese Center for Disease Control and Prevention

Viral hepatitis is an important challenge to public health *** hepatitis B is well controlled due to vaccination,the disease burden caused by the spread of hepatitis C has become increasingly *** C is an infectious disease that is mainly *** rate of chronicity ranges from 55% to 85% after people are infected with the hepatitis C virus （HCV）.

关键词： HCV Figure Epidemiological Analysis on Reported Hepatitis C Cases in China from 2012 to 2016

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Analysis of Knowledge Level and Use of Antiretroviral Pre-Exposure and Post-Exposure Prophylaxis Among MSM—China,2019–2022

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China CDC weekly 2023年第13期5卷 292-296页

作者： Jiahuan Guo Wenting Kang Tongtong Liu Jie Xu Houlin Tang Fan Lyu Guang Zhang National Center for aids/std control and prevention Chinese Center for Disease Control and PreventionBeijingChina Chinese Association of std&aids prevention and control BeijingChina Chinese Center for Health Education BeijingChina

Summary What is already known on this topic?Men who have sex with men(MSM)in China have a high rate of human immunodeficiency virus(HIV)***-exposure prophylaxis(PrEP)and postexposure prophylaxis(PEP)have been shown to be effective in preventing HIV,which may help to contain the HIV epidemic among *** is added by this report?This study found that knowledge and usage of PrEP were low among MSM,indicating that this population is at high risk for HIV *** of PrEP and PEP among MSM is necessary to reduce the risk of HIV infection in this *** are the implications for public health practice?PrEP and PEP are novel HIV prevention strategies that have been demonstrated to be effective and *** further reduce HIV transmission among MSM in China,it is necessary to promote the use of PrEP and PEP.

关键词： prevention MSM immunodeficiency

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