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Liquid flow in scaffold derived from natural source:experimental observations and biological outcome

Regenerative Biomaterials 2022年第1期9卷 480-489页

作者： Elisabetta Salerno Giulia Orlandi Claudio Ongaro Alessandro d’Adamo Andrea Ruffini Gianluca Carnevale Barbara Zardin Jessika Bertacchini Diego Angeli CNR-NANO S3 Research Center on Nanostructures and Biosystems at Surfaces Modena I-41125Italy Department of Sciences and Methods for Engineering University of Modena and Reggio EmiliaReggio Emilia 42122Italy Department of Surgery MedicineDentistry and Morphological Sciences with Interest in TransplantOncology and Regenerative MedicineUniversity of Modena and Reggio EmiliaModena 41125Italy DIEF-Engineering Department“Enzo Ferrari” University of Modena and Reggio EmiliaModena 41125Italy institute of Science and Technology for Ceramics(ISTEC) National Research Council(CNR)Faenza 48018Italy

This study investigates the biological effects on a 3D scaffold based on hydroxyapatite cultured with MC3T3 osteoblasts in response to flow-induced shear stress(FSS).The scaffold adopted here(B-HA)derives from the biomorphic transformation of natural wood and its peculiar channel geometry mimics the porous structure of the *** the point of view of fluid dynamics,B-HA can be considered a network of micro-channels,intrinsically offering the advantages of a microfluidic *** work,for the first time,offers a description of the fluid dynamic properties of the B-HA scaffold,which are strongly connected to its *** features are necessary to determine the FSS ranges to be applied during in vitro studies to get physiologically relevant *** selected ranges of FSS promoted the elongation of the attached cells along the flow direction and early osteogenic cell *** data confirmed the ability of B-HA to promote the differentiation process along osteogenic ***,such a bioactive and naturally derived scaffold can be considered as a promising tool for bone regeneration applications.

关键词： fluid shear stress flow resistance hydroxyapatite 3D scaffold

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A Computational fluid Dynamics Analysis of Air Mixer Distribution Tubes and Improvement of Calculation Accuracy

A Computational Fluid Dynamics Analysis of Air Mixer Distrib...

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The Sixth World Congress on Computational mechanics in Conjunction with the Second Asian-Pacific Congress on Computational mechanicsⅠ

作者： Yasushi Ichikawa Masaaki Kubo Tetsuo Saga Nobuyuki Taniguchi FC Power Plant Development Group FCV Engineering Department NISSAN Motor Co. Ltd. 1 Natsushima-cho Yokosuka-shi Kanagawa 237-8523 Japan Powertrain and Environment Research Labolatry Nissan Research Center institute of Industrial Science University of Tokyo 4-6-1 Komaba Meguro-ku 153-8505 Information Technology Center 2-11-16 Yayoi Bunkyo-ku 113-8658

The fuel reforming system for a fuel cell vehicle requires a compact and low-cost static mixer that can uniformly mix the feed gas regardless of the flow rate. For that reason, the mixer is frequently designed with a simple structure of parallel distribution tubes. Such a gas mixer has multiple tubes arranged in parallel in the cross section of the main duct. Each tube has multiple tiny holes arranged in a row on its wall face through which gas is blown out. However, it is very difficult to achieve uniform flow rates from all the holes under both high and low flow rate *** fluid analysis is effective in solving this problem. Under a low flow rate condition, the flow through the tubes is laminar because of the small Reynolds number associated with the tube diameter, whereas a high flow rate results in turbulent flow because of the large Reynolds ***, at intermediate flow rates, the Reynolds number is in a transitional state. Previously,when a transitional state was present in the calculation area, sufficient prediction accuracy was not obtained because the turbulent model could not be adapted suitably to different parts. Consequently, we adopted a new calculation method that determines the Reynolds number in each flow during a calculation and automatically switches between use and non-use of the turbulent model. The calculated results were compared with experimental measurements obtained by 3-D stereo particle image velocimetry (PIV). Good agreement was seen between the two sets of results, which confirmed the validity of the new calculation method.

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组织工程骨和外科人工植入物的仿生技术研究

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中国组织工程研究与临床康复 2008年第14期12卷 2721-2726页

作者：雷万军李秉哲曹谊林 Karl Ulrich Kainero 彭淑鸽崔磊周宁生河南科技大学医学技术及工程学院河南省洛阳市471003 上海第二医科大学附属第九人民医院整形外科上海市组织工程研究与开发中心上海市200011 GKSS Research Center Institute for Materials ResearchCenter for Magnesium Technology D-21502 Geesthacht Germany

学术背景:虽然已经有应用组织工程骨修复颅颌面骨缺损的报道,但因其缺乏植入早期的力学强度,尚不能应用在四肢负重部位修复骨缺损。目的:探讨负重组织工程骨的新型支架的仿生力学设计、多孔纯镁支架的仿生形态学设计和多孔纯镁支架仿人... 详细信息

学术背景:虽然已经有应用组织工程骨修复颅颌面骨缺损的报道,但因其缺乏植入早期的力学强度,尚不能应用在四肢负重部位修复骨缺损。目的:探讨负重组织工程骨的新型支架的仿生力学设计、多孔纯镁支架的仿生形态学设计和多孔纯镁支架仿人骨材料表面涂层的仿生技术,以及其他负重组织工程骨候选支架仿生技术和外科人工金属植入物仿生表面涂层技术的发展现状。检索策略:应用计算机检索EI数据库1899/2007与仿生材料相关的文献,并以ELSERVIER、Springer、万方外文文献数据库以及CHKI中文数据库文献索引为辅助,英文检索词"Biomimetic materials",中文检索词"仿生学"。纳入与仿生学、仿生力学、仿生材料及技术相关的文章。文献评价:共得到3501个索引,选择35篇完全符合标准的文献进行综述。其中有关仿生学1篇,生物力学1篇,组织工程用仿生材料1篇,负重组织工程骨的新型支架3篇,医学用金属材料的仿生表面涂层技术12篇,医学用生物陶瓷的仿生表面涂层技术1篇,医学用生物高分子聚合物的仿生涂层技术4篇,纳米生物有机物大分子和生物无机物分子的自组装6篇,生物材料的体积修饰或改性2篇。资料综合:①为解决负重组织工程骨早期力学强度不足问题,仿生涂层的多孔纯镁新型支架是临床试用前期研究最佳候选方案,仿生涂层的多孔纯钛支架,可能作为上述研究的其他选择。②多孔双相生物陶瓷支架压缩强度较低,可能不足以解决问题,利用仿生技术对整体修饰或改性可能是有前景的。③多孔生物高分子聚合物支架,可以利用仿生技术对整体修饰或改性以改善力学性能,但是效果非常有限。结论:到目前为止还不能解决负重组织工程骨的早期力学性能不足问题。外科植入物金属,以及多孔生物金属、生物陶瓷、生物高分子聚合物等组织工程骨支架表面,均可利用仿生涂层技术进行表面修饰或改性。

关键词：负重组织工程骨多孔纯镁支架仿生涂层仿生技术生物材料

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水性轮转凹印油墨在PET和BOPP基材上印刷的对比研究

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中国印刷与包装研究 2009年第1期1卷 108-109页

作者： Jang-Woo Lee Kwang Kil Mun Young Tai Yoo institute of Intelligent Vehicle and System Technology Konkuk University 1 Hwayang-dong Gwangjin-gu Seoul143-701 Republic of Korea Continuous Process Research Center 1 Hwayang-dong Gwangjin-gu Seoul 143-701 Republic of Korea Department of Materials Chemistry and Engineering College of Engineering Konkuk University 1 Hwayang-dongGwangjin-gu Seoul 143-701 Republic of Korea

采用凹印机(最大速度500m/min)在PET(聚对苯二甲酸乙二醇酯)和BOPP(双向拉伸聚丙烯)承印物上进行印刷试验,以研究高速凹版印刷下油墨的转移情况和印刷适性。将水性油墨用酒精稀释后,在特定的印刷速度、印刷压力和网穴尺寸等多种印刷设... 详细信息

采用凹印机(最大速度500m/min)在PET(聚对苯二甲酸乙二醇酯)和BOPP(双向拉伸聚丙烯)承印物上进行印刷试验,以研究高速凹版印刷下油墨的转移情况和印刷适性。将水性油墨用酒精稀释后,在特定的印刷速度、印刷压力和网穴尺寸等多种印刷设备条件下对柔性承印物进行印刷。采用光学显微镜、UV可见光谱仪和原子力显微镜(AFM)测量印刷图像和油墨转移率。通过对界面张力、黏度以及油墨与承印物之间润湿角的测量与评价,定量分析它们对印刷特性的影响。实验结果表明,影响印刷特性的最重要的因素是油墨黏度、表面张力和界面张力。稀释后的油墨在PET和BOPP薄膜上的铺展系数都小于零,也就是说油墨难以在二者上顺利铺展,因此,扩散可能是由于剪切力导致油墨流动。显微镜或光谱仪测量表明,在各种试验印刷设备条件下,印刷速度不会对PET薄膜上印刷图像的均匀性和色度产生很大影响,而BOPP薄膜上的图像质量则在很大程度上依赖于转速。两者存在差异的主要原因在于BOPP薄膜多孔表面的毛细管堵塞导致油墨的铺展能力降低。此外,网穴尺寸(网点百分比)增大导致色度增大,其原因在于油墨和承印物间的接触面积变大。尤其对于BOPP薄膜来说,其印刷图像的色度会随着网点百分比的增大而线性增大。应该指出,在相同的稀释条件和设备条件下,较之PET薄膜来说,BOPP薄膜上的印刷图像的色度与墨层厚度远远高于PET薄膜。BOPP与PET薄膜在油墨转移率上的较大差异也许可以在一定程度上解释两者在界面张力上的差异,以及BOPP承印物上的吸收现象。

关键词：卷筒纸凹印油墨转移聚合承印物水性油墨印刷设备条件

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Micropolar fluid flow and heat transfer over exponentially permeable shrinking sheet

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Propulsion and Power Research 2016年第4期5卷 310-317页

作者： Aurangzaib Md.Sharif Uddin Krishnendu Bhattacharyya Sharidan Shafie Department of Mathematical Sciences Federal Urdu University of ArtsScience&TechnologyGulshan-e-IqbalKarachiPakistan Mathematics Discipline Khulna UniversityKhulna 9208Bangladesh Department of Mathematics Institute of ScienceBanaras Hindu UniversityVaranasi 221005Uttar PradeshIndia Department of Mathematics The University of BurdwanBurdwan 713104West BengalIndia Department of Mathematical Sciences Faculty of ScienceUnh ersiti Teknologi MalaysiaSkudaiJohor Bahru 81310JohorMalaysia

The importance of boundary layer flow of micropolar fluid and heat transfer over an exponentially penneable shrinking sheet is *** similarity approach is adopted and self-similar ordinary differential equations are obtained and then those are solved numerically using very efficient shooting *** to that of Newtonian fluid flow case,here also dual similarity solutions for velocity,microrotation and temperature are obtained when certain amount of mass suction is applied through the porous *** steady flow of micropolar fluid over exponentially shrinking porous sheet the mass suction need to be stronger compared to the Newtonian fluid *** dual velocity,microrotation,and temperature profiles it is found that the velocity decreases with material parameter(related to micropolar fluid)for first solution and it increases for second,whereas the effects are opposite for fluid *** the other hand,for larger material parameter microrotation profile reduces for both types of *** it significant that the skin friction coefficient,the couple stress coefficient and the heat transfer coefficient show similar variation with increasing material parameter,all those physical quantities decrease for first solution and increase for second solution.

关键词： Micropolar fluid flow Heat transfer Dual solutions Shrinking sheet Exponential velocity

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