检索结果-南通市图书馆

Nanoparticles for the treatment of spinal cord injury

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1665-1680页

作者： Qiwei Yang Di Lu Jiuping Wu Fuming Liang Huayi Wang Junjie Yang Ganggang Zhang Chen Wang Yanlian Yang Ling Zhu Xinzhi Sun Department of Orthopedic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina CAS Key Laboratory of Standardization and Measurement for nanotechnology CAS Key Laboratory for Biomedical Effects of Nanomaterials and NanosafetyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijingChina University of Chinese Academy of Sciences BeijingChina Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Spinal cord injuries lead to significant loss of motor, sensory, and autonomic functions, presenting major challenges in neural regeneration. Achieving effective therapeutic concentrations at injury sites has been a slow process, partly due to the difficulty of delivering drugs effectively. Nanoparticles, with their targeted delivery capabilities, biocompatibility, and enhanced bioavailability over conventional drugs, are garnering attention for spinal cord injury treatment. This review explores the current mechanisms and shortcomings of existing treatments, highlighting the benefits and progress of nanoparticle-based approaches. We detail nanoparticle delivery methods for spinal cord injury, including local and intravenous injections, oral delivery, and biomaterial-assisted implantation, alongside strategies such as drug loading and surface modification. The discussion extends to how nanoparticles aid in reducing oxidative stress, dampening inflammation, fostering neural regeneration, and promoting angiogenesis. We summarize the use of various types of nanoparticles for treating spinal cord injuries, including metallic, polymeric, protein-based, inorganic non-metallic, and lipid nanoparticles. We also discuss the challenges faced, such as biosafety, effectiveness in humans, precise dosage control, standardization of production and characterization, immune responses, and targeted delivery in vivo. Additionally, we explore future directions, such as improving biosafety, standardizing manufacturing and characterization processes, and advancing human trials. Nanoparticles have shown considerable progress in targeted delivery and enhancing treatment efficacy for spinal cord injuries, presenting significant potential for clinical use and drug development.

关键词： antioxidants axon regeneration biocompatible materials drug carriers nanoparticles nerve regeneration neuroinflammatory diseases neuroprotection spinal cord injury stem cells

Tuning the interfacial reaction environment via pH-dependent and induced ions to understand C–N bonds coupling performance in NO3- integrated CO2 reduction to carbon and nitrogen compounds over dual Cu-based N-doped carbon catalyst

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 273-285页

作者： Tianhang Zhou Chen Shen Zhenghao Wu Xingying Lan Yi Xiao College of Carbon Neutrality Future Technology State Key Laboratory of Heavy Oil Processing China University of Petroleum (Beijing) institute of Materials Science TU Darmstadt Department of Chemistry Xi'an Jiaotong-Liverpool University Department of Mechanical and Mechatronics Engineering and Waterloo Institute of Nanotechnology University of Waterloo Waterloo

Dual atomic catalysts （DAC）,particularly copper （Cu2）-based nitrogen （N） doped graphene,show great potential to effectively convert CO2and nitrate （NO3-） into important industrial chemicals such as ethylene,glycol,acetamide,and urea through an efficient catalytical process that involves C–C and C–N ***,the origin of the coupling activity remained unclear,which substantially hinders the rational design of Cu-based catalysts for the N-integrated CO2reduction reaction （CO2RR）.To address this challenge,this work performed advanced density functional theory calculations incorporating explicit solvation based on a Cu2-based N-doped carbon (Cu2N6C10) catalyst for *** calculations are aimed to gain insight into the reaction mechanisms for the synthesis of ethylene,acetamide,and urea via coupling in the interfacial reaction *** to the sluggishness of CO2,the formation of a solvation electric layer by anions （F-,Cl-,Br-,and I-） and cations (Na+,Mg2+,K+,and Ca2+) leads to electron transfer towards the Cu *** process significantly accelerates the reduction of *** results reveal that*CO intermediates play a pivotal role in N-integrated ***,the Cu2-based N-doped carbon catalyst examined in this study has demonstrated the most potential for C–N coupling to *** findings reveal that through the process of a condensation reaction between*CO and NH2OH for urea synthesis,*NO3-is reduced to*NH3,and*CO2to*CCO at dual Cu atom *** dual-site reduction facilitates the synthesis of acetamide through a nucleophilic reaction between NH3and the ketene ***,we found that the I-and Mg2+ions,influenced by pH,were highly effective for acetamide and ammonia synthesis,except when F-and Ca2+were ***,the mechanisms of C–N bond formation were investigated via ab-initio molecular dynamics simulations,and we found that adjusting the micro-environment can change the dominant side reaction,shift

关键词： Condensation reactions

Nonlinear vibration analysis of laminated composite Mindlin micro/nano-plates resting on orthotropic Pasternak medium using DQM

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2015年第8期36卷 1033-1044页

作者： A.G.ARANI G.S.JAFARI Faculty of Mechanical Engineering University of Kashan institute of nanoscience & nanotechnology University of Kashan

The nonlocal nonlinear vibration analysis of embedded laminated micro- plates resting on an elastic matrix as an orthotropic Pasternak medium is investigated. The small size effects of micro/nano-plate are considered based on the Eringen nonlocal theory. Based on the orthotropic Mindlin plate theory along with the von Kármán geo- metric nonlinearity and Hamilton＇s principle, the governing equations are derived. The differential quadrature method （DQM） is applied for obtaining the nonlinear frequency of system. The effects of different parameters such as nonlocal parameters, elastic me- dia, aspect ratios, and boundary conditions are considered on the nonlinear vibration of the micro-plate. Results show that considering elastic medium increases the nonlinear frequency of system. F^lrthermore, the effect of boundary conditions becomes lower at higher nonlocal parameters.

关键词： nonlinear vibration laminated micro-plate orthotropic Pasternak medium,differential quadrature method

Nonlocal buckling of embedded magnetoelectroelastic sandwich nanoplate using refined zigzag theory

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2018年第4期39卷 529-546页

作者： A.GHORBANPOUR-ARANI F.KOLAHDOUZAN M.ABDOLLAHIAN Faculty of Mechanical Engineering University of Kashan institute of nanoscience & nanotechnology University of Kashan

This paper is concerned with a buckling analysis of an embedded nanoplate integrated with magnetoelectroelastic(MEE) layers based on a nonlocal magnetoelectroelasticity theory. A surrounding elastic medium is simulated by the Pasternak foundation that considers both shear and normal loads. The sandwich nanoplate(SNP) consists of a core that is made of metal and two MEE layers on the upper and lower surfaces of the core made of Ba Ti O3/Co Fe2 O4. The refined zigzag theory(RZT) is used to model the SNP subject to both external electric and magnetic potentials. Using an energy method and Hamilton’s principle, the governing motion equations are obtained, and then solved analytically. A detailed parametric study is conducted, concentrating on the combined effects of the small scale parameter, external electric and magnetic loads, thicknesses of MEE layers, mode numbers, and surrounding elastic medium. It is concluded that increasing the small scale parameter decreases the critical buckling loads.

关键词： sandwich nanoplate(SNP) refined zigzag theory(RZT) nonlocal magnetoelectroelasticity theory buckling magnetostrictive layer

Bimetallic Single‑Atom Catalysts for Water Splitting

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 1-45页

作者： Megha A.Deshmukh Aristides Bakandritsos Radek Zbořil nanotechnology Centre Centre for Energy and Environmental TechnologiesVŠB–Technical University of Ostrava17.listopadu 2172/1570800 Ostrava‑PorubaCzech Republic Regional Centre of Advanced Technologies and Materials Czech Advanced Technology and Research Institute(CATRIN)Palacky University OlomoucŠlechtitelů241/2778371 Olomouc–HoliceCzech Republic

Green hydrogen from water splitting has emerged as a critical energy vector with the potential to spearhead the global transition to a fossil fuel-independent *** field of catalysis has been revolutionized by single-atom catalysts(SACs),which exhibit unique and intricate interactions between atomically dispersed metal atoms and their ***,bimetallic SACs(bimSACs)have garnered significant attention for leveraging the synergistic functions of two metal ions coordinated on appropriately designed *** offer an avenue for rich metal–metal and metal–support cooperativity,potentially addressing current limitations of SACs in effectively furnishing transformations which involve synchronous proton–electron exchanges,substrate activation with reversible redox cycles,simultaneous multi-electron transfer,regulation of spin states,tuning of electronic properties,and cyclic transition states with low activation *** review aims to encapsulate the growing advancements in bimSACs,with an emphasis on their pivotal role in hydrogen generation via water *** subsequently delve into advanced experimental methodologies for the elaborate characterization of SACs,elucidate their electronic properties,and discuss their local coordination ***,we present comprehensive discussion on the deployment of bimSACs in both hydrogen evolution reaction and oxygen evolution reaction,the two half-reactions of the water electrolysis process.

关键词： Single-atom catalysts Single-atom dimers Hydrogen evolution Oxygen evolution Water splitting

Dynamic surface wettability of three-dimensional graphene foam

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2014年第4期23卷 472-475页

作者：黄文斌王广龙高凤岐乔中涛王刚陈闽江陶立邓娅孙连峰 institute of nanotechnology and Microsystems Mechanical Engineering College National Center for nanoscience and Technology

In this work, three-dimensional graphene foams （GFs） are synthesized and characterized by scanning electron micro- scope （SEM） and Raman spectroscopy. The SEM images indicate that after the growth of graphene, the graphene covers the surface of nickel （Ni） foam uniformly. Raman spectra show that the percentages of monolayer, bilayer, trilayer, and multilayer graphenes are - 58%, - 32%, - 8%, and ,.o 2%, respectively. The contact angle （CA）（-- 12°） of water droplet （3 p-L） on GF is found to be larger than that on Ni foam （,- 107°）, indicating that graphenes have changed the surface wettability of the Ni foam. Meanwhile, the dynamic characteristics of CA of water droplet on GF are different from those on Ni foam. The mechanisms for different behaviors are discussed, which are attributed to volatilization and seepage of water droplets.

关键词： graphene foam CVD surface wettability contact angle

Enhancing the powering ability of triboelectric nanogenerator through output signal’s management strategies

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第9期16卷 11783-11800页

作者： Changxin Qi Zhenyue Yang Jinyan Zhi Ruichao Zhang Juan Wen Yong Qin institute of nanoscience and nanotechnology School of Materials and EnergyLanzhou UniversityLanzhou 730000China

As a new branch of efficient and low-cost mechanical energy conversion technology,triboelectric nanogenerator(TENG)is a potential solution to provide a long-term power supply for the Internet of Things(IoT)sensors and portable electronic ***,due to inherent working properties of TENG itself such as extremely high internal impedance,pulse,and alternating current(AC)output,TENG can not directly supply power to loads such as batteries *** on these,we describe TENG’s performance from a new perspective of powering *** consists of two aspects:the ability to transport charge effectively and the ability to output high power quality current *** order to push forward the developments and applications of TENG,it is necessary to improve its power supply capacity from different ***,in recent years,a variety of output signal’s management strategies aiming at effectively managing the generated electricity and significantly improving powering ability of TENG have obtained significantly ***,this paper discusses the working mechanisms and different load characteristics of TENG at first to clarify the electric performance of ***,on basis of theoretical analysis,the output signal’s management strategies are elaborated from four aspects:improving the cycle output electricity of TENG,increasing the surface charge density of TENG,improving the power quality of TENG-based energy harvesting system,promoting the application of TENG through integrated circuit(IC)technology and TENG network,and the relevant principles and applications are discussed ***,the advantages and disadvantages of the above output signal’s management strategies are summarized and discussed,and the future development of the output signal’s management strategies for TENG is prospected.

关键词： triboelectric nanogenerator(TENG) inherent working properties TENG-based energy harvesting system powering ability output signal’s management strategies.

Electrochemically Assisted Photocatalytic Oxidation of Methanol on TiO_2 Nanotube Arrays

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2010年第6期26卷 535-541页

作者： R.Mohammadpour A.Iraji zad N.Taghavinia M.Rahman M.M.Ahadian institute for nanoscience and nanotechnology Sharif University of Technology Department of Physics Sharif University of Technology

The influence of an externally applied bias on photocatalytic performance of crystallized TiO2/Ti nanotubular electrode formed by anodization in fluoride-based electrolyte were investigated and compared to the behavior of multiporous TiO2 electrode. The photoelectrocatalytic oxidation behavior of methanol over the nanotubular electrode has been studied by measuring photocurrent response, potentiodynamic polarization spectroscopy and using electrochemical impedance spectroscopy （EIS）. It was found that the photoelectrocatalytic oxida- tion and the charge transfer rate constant of reaction on TiO2/Ti nanotubular electrode can significantly be increased by applying electrochemical bias. Moreover, TiO2 electrodes have considerably better performance alytic performance. based on the results, it was found that the nanotubular in comparison with porous samples in photoelectrocatalytic performance.

关键词： TiO2 nanotube Photoelectrocatalyst Electrochemical impedance spectroscopy Methanol

Operando and reversible manipulation of Pt electrocatalytic properties through its substrate phase transition

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年

作者： Hongfei Liu Yi Xie Changzheng Wu institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China Key Laboratory of Precision and Intelligent Chemistry School of Chemistry and Materials ScienceCollaborative Innovation Center of Chemistry for Energy Materials (iChEM)and CAS Center for Excellence in NanoscienceUniversity of Science and Technology of China institute of Energy Hefei Comprehensive National Science Center

The lattice strain is considered critical for determining the catalytic activity of metal catalysts such as Pt. However, the dynamic manipulation of Pt lattice strain under reaction conditions to directly examine its catalytic effect has not been achieved. In this study, we realized the reversible manipulation of Pt electrocatalytic properties under electrochemical conditions by tuning the Pt lattice strain with the temperature-controlled Martensite-Austenite phase transition of the shape memory NiTi alloy *** enabled establishing a straightforward relationship between the strain-induced electronic structure transformation and electrocatalytic activity leaping. The binding strength between Pt and surface oxygen species was confirmed as the critical factor that dominated the hydrogen evolution and the oxygen reduction activities. In contrast, the oxygen evolution activity was barely affected by NiTi substrate phase transition.

关键词：