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Associations between physical activity levels and ATPase inhibitory factor 1 concentrations in older adults

Journal of Sport and Health Science 2024年第3期13卷 409-418页

作者： Jérémy Raffin Yves Rolland Annelise Genoux Guillaume Combes Mikael Croyal Bertrand Perret Sophie Guyonnet Bruno Vellas laurent O.Martinez Philipe de Souto Barreto For the MAPT/DSA Group institut du Vieillissement Gérontopôle de ToulouseCentre Hospitalo-Universitaire de ToulouseToulouse 31000France Centre d'Epidémiologie et de recherche en Santédes Populations UnitéMixte de Recherche 1295Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse-III-Paul-SabatierToulouse 31000France LimitAging Team Institut des Maladies Métaboliques et CardiovasculairesUnitéMixte de Recherche 1297Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse III-Paul SabatierToulouse 31432France Service de Biochimie Pôle de biologieHôpital de PurpanCentre Hospitalo-Universitaire de ToulouseToulouse 31300France L'institut du Thorax Institut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France BioCore US16Structure Fédérative de Recherche BonamyInstitut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France Plate-forme de spectrométrie de masse Centre de Recherche en Nutrition HumaineOuestNantes 44000France 不详

Background:Adenosine triphosphatase inhibitory factor 1(IF1)is a key protein involved in energy ***1 has been linked to various agerelated diseases,although its relationship with physical activity(PA)remains ***,the apolipoprotein A-I(apoA-I),a PA-modulated lipoprotein,could play a role in this relationship because it shares a binding site with IF1 on the cell-surface ATP *** examined here the associations between chronic PA and plasma IF1 concentrations among older adults,and we investigated whether apoA-I mediated these ***:In the present work,1096 healthy adults(63.8%females)aged 70 years and over who were involved in the Multidomain Alzheimer Prevention Trial study were ***1 plasma concentrations(square root of ng/mL)were measured at the 1-year visit of the Multidomain Alzheimer Prevention Trial,while PA levels(square root of metabolic equivalent task min/week)were assessed using questionnaires administered each year from baseline to the 3-year *** linear regressions were performed to investigate the associations between the first-year mean PA levels and IF1 *** analyses were conducted to examine whether apoA-I mediated these *** linear regressions were carried out to investigate whether the 1-year visit IF1 concentrations predicted subsequent changes in ***:Multiple linear regressions indicated that first-year mean PA levels were positively associated with IF1 concentrations(B=0.021;SE=0.010;p=0.043).Mediation analyses revealed that about 37.7%of this relationship was mediated by apoA-I(B_(ab)=0.008;SE=0.004;p=0.023).Longitudinal investigations demonstrated that higher concentrations of IF1 at the 1-year visit predicted a faster decline in PA levels over the subsequent 2 years(time×IF1:B=0.148;SE=0.066;p=0.025).Conclusion:This study demonstrates that regular PA is associated with plasma IF1 concentrations,and it suggests that apoA-I partly med

关键词： Aging Apolipoprotein Bioenergetics Exerkine Mitochondria

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The interactive effect of temperature and fertilizer types determines the dominant microbes in nitrous oxide emissions and the dicyandiamide efﬁcacy in a vegetable soil

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Soil Ecology Letters 2024年第3期6卷 121-133页

作者： Xiaoya Xu Haiyang Liu Yaowei Liu Didier Lesueur laetitia Herrmann Hongjie Di Caixian Tang Jianming Xu Yong Li Zhejiang Provincial Key laboratory of Agricultural Resources and Environment College of Environmental and Resource SciencesZhejiang UniversityHangzhou 310058China College of Geography and Environment Shandong Normal UniversityJinan 250014China Centre de Coopération Internationale en recherche agronomique pour le Développement(CIRAD) UMR Eco&SolsHanoiVietnam Eco&Sols Universitéde Montpellier(UMR)CIRADInstitut National de Recherche pour l’Agriculturel’Alimentation et l’Environnement(INRAE)Institut de Recherche pour le Développement(IRD)Montpellier SupAgro34060 MontpellierFrance Alliance of Biodiversity International and International Center for Tropical Agriculture(CIAT) Asia hubCommon Microbial Biotechnology Platform(CMBP)HanoiVietnam School of Life and Environmental Sciences Faculty of ScienceEngineering and Built Environment–Deakin UniversityMelbourneVIC 3125Australia Rubber Research institute Chinese Academy of Tropical Agricultural SciencesHaikou 571737China la Trobe institute for Sustainable Agriculture and Food Department of AnimalPlant&Soil SciencesLa Trobe UniversityBundooraVic 3086Australia

Heat waves associated with global warming and extreme climates would arouse serious consequences on nitrogen(N)***,the responses of the functional guilds to different temperatures,especially high temperature and the cascading effect on N_(2)O emissions remain *** incubation study was conducted to examine the effect of different temperatures(20°C,30°C,and 40°C)and fertilizer types(urea and manure)on N_(2)O-producers and N_(2)O-reducers,as well as the efficacy of dicyandiamide(DCD)on N_(2)O emissions in a vegetable *** showed that ammonia oxidizers and nirS-type denitrifiers were well adapted to high temperature(40°C)with manure application,while the fungal nirK-denitrifiers had better tolerance with urea *** nosZ clade I microbes had a strong adaptability to various temperatures regardless of fertilization type,while the growth of nosZ clade II group microbes in non-fertilized soil(control)were significantly inhibited at higher *** N_(2)O emissions were significantly decreased with increasing temperature and DCD application(up to 60%,even at 40°C).Under high temperature conditions,fungal denitrifiers play a significant role in N-limited soils(non-fertilized)while nirS-type denitrifiers was more important in fertilized soils in N_(2)O emissions,which should be specially targeted when mitigating N_(2)O emissions under global warming climate.

关键词： nitrogen fertilizer microorganisms nitrification inhibitor bacteria archaea fungi

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Electrochemical Activation-Induced Structural Transformation in Ni（OH）2/Ti3C2Tx/NF Systems with Enhanced Electrochemical Performance for Hybrid Supercapacitors

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Energy & Environmental Materials 2024年第4期7卷 277-284页

作者： Chuming Xu Lu Dai Yiming Zhao Shuang Li Yapan Wu Xueqian Wu Gaixia Zhang Shuhui Sun Dongsheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Department of Electrical Engineering école de Technologie Supérieure (éTS) institut national de la recherche Scientifique (INRS) Centre énergie Matériaux Télécommunications

Exploring a novel strategy for large-scale production of battery-type Ni（OH）2-based composites,with excellent capacitive performance,is still greatly ***,we developed a facile and cost-effective strategy to in situ grow a layer of Ni（OH）2/Ti3C2Txcomposite on the nickel foam（NF） collector,where Ti3C2Txis not only a conductive component,but also a catalyst that accelerates the oxidation of NF to Ni（OH）2.

关键词： electrochemical activation hybrid supercapacitors Ni(OH)2 Ti3C2Tx

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Virtual brain twins: from basic neuroscience to clinical use

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national Science Review 2024年第05期 72-86页

作者： Huifang E.Wang Paul Triebkorn Martin Breyton Borana Dollomaja Jean-Didier Lemarechal Spase Petkoski Pierpaolo Sorrentino Damien Depannemaecker Meysam Hashemi Viktor K.Jirsa Aix Marseille Université Institut National de la Santéet de la Recherche Médicale Institut de Neurosciences des Systèmes(INS) UMR1106 Service de Pharmacologie Clinique et Pharmacosurveillance AP–HM

Virtual brain twins are personalized, generative and adaptive brain models based on data from an individual's brain for scientific and clinical use. After a description of the key elements of virtual brain twins,we present the standard model for personalized whole-brain network models. The personalization is accomplished using a subject's brain imaging data by three means:(1) assemble cortical and subcortical areas in the subject-specific brain space;(2) directly map connectivity into the brain models, which can be generalized to other parameters; and(3) estimate relevant parameters through model inversion, typically using probabilistic machine learning. We present the use of personalized whole-brain network models in healthy ageing and five clinical diseases: epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and psychiatric disorders. Specifically, we introduce spatial masks for relevant parameters and demonstrate their use based on the physiological and pathophysiological hypotheses. Finally, we pinpoint the key challenges and future directions.

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Strategies to achieve effective nitrogen activation

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Carbon Energy 2024年第5期6卷 137-163页

作者： Bin Chang Huabin Zhang Shuhui Sun Gaixia Zhang KAUST Catalysis Center(KCC) King Abdullah University of Science and Technology(KAUST)ThuwalKingdom of Saudi Arabia institut national de la recherche Scientifique(INRS) CentreÉnergie Matériaux TélécommunicationsVarennesQuébecCanada Department of Electrical Engineering École de Technologie Supérieure(ÉTS)MontréalQuébecCanada

Ammonia serves as a crucial chemical raw material and hydrogen energy *** electrocatalytic nitrogen reduction reaction(NRR),powered by renewable energy,has attracted tremendous interest during the past few *** some achievements have been revealed in aqueous NRR,significant challenges have also been *** activity and selectivity are fundamentally limited by nitrogen activation and competitive hydrogen *** review focuses on the hurdles of nitrogen activation and delves into complementary strategies,including materials design and system optimization(reactor,electrolyte,and mediator).Then,it introduces advanced interdisciplinary technologies that have recently emerged for nitrogen activation using high-energy physics such as plasma and *** a better understanding of the corresponding reaction mechanisms in the coming years,these technologies have the potential to be extended in further *** review provides further insight into the reaction mechanisms of selectivity and stability of different reaction *** then recommend a rigorous and detailed protocol for investigating NRR performance and also highlight several potential research directions in this exciting field,coupling with advanced interdisciplinary applications,in situ/operando characterizations,and theoretical calculations.

关键词： activation via mediators catalyst optimization electrochemical nitrogen fixation high-energy activation of nitrogen nitrogen

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Trends of land Use and land Cover Change in the Savannah Ecological of the Protected Area Reserve Partielle de Dosso, Niger

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Natural Resources 2024年第3期15卷 61-68页

作者： Amadou Issoufou Abdourhimou Moussa Boubacar Habou Rabiou Soumana Idrissa Mahamane Ali Faculté des Sciences agronomiques Université de Diffa Diffa Niger institut national de la recherche agronomique du Niger Niamey Niger Faculté des Sciences et Techniques Université Abdou Moumouni de Niamey Niamey Niger

Information on the dynamics of savannah is important to a country's plan to overcome the problems of uncontrolled development and environmental hazards. Taking the reserve partielle de Dosso, Niger as the case study area, this paper analyzed the long-term land use land cover change from 2002 to 2022. Satellite images were processed by using Google Earth Engine (GEE). Therefore, four major land cover classes were identified based on spectral characteristics of land sat, namely, built-up, vegetation, cropland, bare land and water. The result revealed that barren and built-up areas increased at the expense of vegetation and water. From the four major land use land cover the large area is covered by vegetation which comprises about 192963.5 hectares followed by cropland and water consisting of 32506.43 and 1596.4 hectares respectively. The built-up area gained substantial area (most) during the study period. The reduction in some of the land cover/uses underlines the dangerous trend of the pressure poised by population growth and the changing functionality. land cover change is influenced by a variety of societal factors operating on several spatial and temporal levels. The area estimates and spatial distributions of the LULC classes produced from the current study will assist local authorities, managers, and other stakeholders in decision-making and planning regarding forest land cover and uses.

关键词： land Use/Cover Change Detection Classification Dosso

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Approaching the commercial threshold of solar water splitting toward hydrogen byⅢ-nitrides nanowires

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Frontiers in Energy 2024年第1期18卷 122-124页

作者： Baowen ZHOU Shuhui SUN Key laboratory for Power Machinery and Engineering of the Ministry of Education School of Mechanical EngineeringShanghai Jiao Tong UniveristyShanghai 200240China institut national de la recherche Scientifique(INRS)-CenterÉnergie Matériaux Télécommunications VarennesQuebec J3X 1P7Canada

In a recent article in Nature,Mi and coworkers from the University of Michigan reported a solar-to-hydrogen(STH)efficiency of>9%in converting water into hydrogen and oxygen[1],which represents an important breakthrough in this field due to the benchmarking leap in STH efficiency of photocatalytic overall water splitting under natural sunlight.

关键词： breakthrough splitting Michigan

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Cholinesterase Activity as an Indicator of Health Risks among Kou Valley Farmers

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Journal of Biosciences and Medicines 2024年第7期12卷 71-86页

作者： Thiombiano Cherileila Hien S. Aristide Koevi Nadège Bayili Bazoma Ouattara Abdoulaye Traore Patrice Traore T. Isidore Hien Herve Centre Muraz Institut National de Sant Publique (INSP) Bobo-Dioulasso Burkina Faso institut Suprieur des Science de la Sant (INSSA) University of Nazi Boni Bobo-Dioulasso Burkina Faso institut de recherche en Science de la Sant (IRSS) Centre National de Recherche Scientifique et Technologique (CNRST) Ouagadougou Burkina Faso

Introduction: Pesticides are currently an essential component of agricultural production techniques for controlling pests and weeds. In Burkina Faso, non-compliance with good practice in the use of pesticides poses a real health problem for the population. This study examines the health risks associated with pesticide management in rice-growing areas. Material and Methods: A field survey was conducted in Bama, involving farmers, focusing on their socio-demographic characteristics, pesticide usage, and health effects. Cholinesterase levels were measured in subsample of farmers using a portable device. Data were analysed using Microsoft Excel, calculating means and percentages for various practices. Health consultations, protection methods, and pesticide management were studied. Erythrocyte acetylcholinesterase activity was compared before and after treatment. Data were categorised into classes based on inhibition levels, and correlation analyses determined relationships between variables such as age, years of experience, and cholinesterase activity. Results: The results indicate that rice cultivation is mainly carried out by a fairly young population, with nearly 63% being under the age of 50. Common poor practices in pesticide use include improper storage and reuse of leftover pesticides. Seven types of pesticides were identified, including organophosphates such as glyphosate, which was used in 26.7% of cases. This organophosphate has resulted in class B poisoning, causing a 30% - 50% reduction in erythrocyte cholinesterase activity. The health effects of pesticide use are felt by agricultural farmers through various symptoms of poisoning. Conclusion: To reduce the occurrence of pesticide poisoning, it is essential to launch information and awareness campaigns among the population and farmers to promote safe practices in pesticide use in Bama, Burkina Faso.

关键词： Pesticides Environmental Sanitary Risk Acetylcholinesterase Farmers Bama Burkina Faso

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Case Study for Undetermined Mosquito Species by Polymerase Chain Reaction in Western Burkina Faso

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American Journal of Molecular Biology 2024年第2期14卷 43-53页

作者： Koudraogo Bienvenue Yaméogo Sassan Simplice Kambou Domonbabélé François de Sales Hien Logotio Rachel Angela Traore Franck Adama Yao Rakiswendé Serge Yerbanga Centre national de la recherche Scientifique et Technologique CNRST Institut de Recherche en Sciences de la Sante (IRSS) Laboratoire de recherche sur les maladies infectieuses et parasitaires Bobo-Dioulasso Burkina Faso institut des Sciences et Techniques (INSTech Bobo) Avenue de Sya Bobo-Dioulasso Burkina Faso

Introduction: Malaria eradication campaigns all over the world are largely based on parasite and vector control. Vector identification, whether morphological or molecular, is an essential component of vector control. This study analyzed the possible causes of indeterminate polymerase chain reaction (PCR) results for mosquito species in Western part of Burkina Faso. Methodology: From July 2021 to November 2021, mosquitoes were collected during the period of high malaria transmission in the village of Séguéré, Houet province, Burkina Faso, and morphologically identified. After DNA extraction, samples were amplified by sine 200× PCR to identify species of the Anopheles gambiae complex. Indeterminate samples were then selected for further analysis. The parameters studied were: DNA dilution, the effect of protocol adjusting, and the type of protocol used. Results: A total of 130 “indeterminate” DNAs diluted 1:10 were analyzed. After dilution, the mean amount was 14.73 ± 3.59 ng/μL and absorbance 1.71 ± 0.1. PCR chain reaction yielded 94.62% (123/130) anopheline species in SINE PCR, 5.38% (7/130) “negative”. A significant difference between SINE PCR before dilution and after dilution was observed (P < 0.001). Identification tests carried out using other protocols gave no positive results. From these results, we note that the adaptation of the protocol significantly reduced the polymerase amplification results of the species. Conclusion: It is therefore necessary to respect the amplification protocols. However, the persistence of “indeterminate” results suggests that further studies should be carried out to shed more light on the subject.

关键词： Malaria Vector DNA PCR

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Advancements on metal oxide semiconductor photocatalysts in photo-electrochemical conversion of carbon dioxide into fuels and other useful products

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Frontiers in Energy 2024年第2期18卷 187-205页

作者： Jai PRAKASH Zhangsen CHEN Shakshi SAINI Gaixia ZHANG Shuhui SUN Department of Chemistry National Institute of Technology HamirpurHamirpur 177005India institut national de la recherche Scientifique(INRS) Centre Énergie Matériaux TélécommunicationsVarennes J3X 1P7Canada Department of Chemistry Indian Institute of Technology MandiHimachal PradeshIndia Department of Electrical Engineering École de Technologie SupérieureMontréal H3C 1K3Canada

Due to its fascinating and tunable optoelectronic properties,semiconductor nanomaterials are the best choices for multidisciplinary ***,the use of semiconductor photocatalysts is one of the promising ways to harness solar energy for useful applications in the field of energy and *** recent years,metal oxide-based tailored semiconductor photocatalysts have extensively been used for photocatalytic conversion of carbon dioxide(CO_(2))into fuels and other useful products utilizing solar *** is very significant not only from renewable energy consumption but also from reducing global warming point of *** current research activities are promising for a better future of *** present mini-review is focused on recent developments(2–3 years)in metal oxide semiconductor hybrid photocatalysts-based photo-electrochemical conversion of CO_(2)into fuels and other useful ***,general mechanism of photo-electrochemical conversion of CO_(2)into fuels or other useful products has been ***,various metal oxide-based emerging hybrid photocatalysts including tailoring of their morphological,compositional,and optoelectronic properties have been discussed with emphasis on their role in enhancing photoelectrochemical ***,mechanism of their photo-electrochemical reactions and applications in CO_(2)conversion into fuels/other useful products have been ***,challenges and future prospects have been discussed followed by a summary.

关键词： metal-oxide semiconductors nanohybrid photocatalysts photo-electrochemical CO_(2)conversion tailoring morphology fuels challenges and future prospects

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