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Many faces of neuronal activity manipulation in drosophila

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Neural Regeneration Research 2025年第9期20卷 2574-2576页

作者： Amber Krebs Steffen Kautzmann Christian Klämbt institut für Neuro-und Verhaltensbiologie MünsterGermany

Animals exhibit complex responses to external and internal *** information is computed by interconnected neurons that express numerous ion channels,which modulate the neuronal membrane *** can neuronal activity orchestrate complex motor patterns or allow learning from previous experience?To answer such questions,we need the ability not only to record,but also to modulate neuronal activity in both space(e.g.,neuronal subsets)and time.

关键词： manipulation potential. neuronal

Silicon slow light photonic crystals structures:present achievements and future trends

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Frontiers of Optoelectronics 2011年第3期4卷 243-253页

作者： Eric CASSAN Xavier LE ROUX Charles CAER Ran HAO damien BERNIER delphine MARRIS-MORINI Laurent VIVIEN institut d'electronique Fondamentale Université Paris-Sud CNRS UMR 8622

Slow light in planar photonic structures has attracted for some years an increasing interest due to amazing physical effects it allows or reinforces and to the degrees of freedom it raises for designing new optical functions. Controlling light group velocity is achieved through the use of periodical optical media obtained by nano-structuration of semiconductor wafers at the scale of light wavelength: the so-called photonic crystals. This article reviews present achievements realized in the field of slow light photonic bandgap structures, including the physical principles of slow light to the description of the most advanced integrated optical devices relying on *** and current hot topics related to slow light are discussed to highlight the balance between the advantages and drawbacks of using slow waves in integrated photonic structures. Then, future trends are described, which is focused on the use of slow wave slot waveguides for nonlinear optics and bio-photonic applications.

关键词： slow light photonic crystals silicon photonics integrated optical devices

Millimeter wave band ultra wideband transmitter MMIC

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Journal of Semiconductors 2015年第9期36卷 125-130页

作者：金凌 Nathalie Rolland SVA Communication Technology Co. Ltd institut d'electronique de Microélectronique et de NanotechnologieUSTLVilleneuve d'Ascq CedexFrance

This paper presents a new millimeter-wave （MMW） ultra wideband （UWB） transmitter MMIC which has been developed in an OMMIC 0.1 μm GaAs PHEMT foundry process （ft= 100 GHz） for 22-29 GHz vehicular radar systems. The transmitter is composed of an MMW negative resistance oscillator （NRO）, a power amplifier （PA）, and two UWB pulse generators （PGs）. In order to convert the UWB pulse signal to MMW frequency and reduce the total power consumption, the MMW NRO is driven by one of the UWB pulse generators and the power amplifier is triggered by another UWB pulse generator. The main advantages of this transmitter are： new design, simple architecture, high-precision distance measurements, infinite ON/OFF switch ratio, and low power consumption. The total power consumption of the transmitter MMIC is 218 mW with a peak output power of 5.5 dBm at 27 GHz.

关键词： millimeter-wave ultra wideband transmitter negative resistance oscillator MMIC GaAs pHEMT

Characterization of planar photonic crystals using surface coupling techniques at large wavelengths

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Chinese Optics Letters 2007年第9期5卷 501-503页

作者： Y.Benachour N.Paraire C.N.R.S. UniversitéParis-Sud 11Institut d'Electronique FondamentaleBt.220-91405Orsay CedexFrance

We report a non-destructive characterization of planar two-dimensional （2d） photonic crystals （PhCs） made in silicon on insulator （SOI） wafers using ellipsometric or Fourier transformed infrared （FTIR） spectroscope. At large wavelengths, devices behave as homogeneous isotropic materials defined by an effective filling factor. The experimental results related to the PhC limited dimensions confirm this characterization.

关键词： Characterization of planar photonic crystals using surface coupling techniques at large wavelengths

Like a G6-nal:transcriptional control of G-protein coupled receptors during oligodendroglial development

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Neural Regeneration Research 2025年第7期20卷 2001-2002页

作者： Tim Aberle Michael Wegner institut für Biochemie Friedrich-Alexander-Universität Erlangen-NürnbergErlangenGermany

Multilayered control of myelination:Quick,saltatory conduction of action potentials along nerve fibers requires the electrical insulation of axons by myelinating *** the central nervous system,this role is taken up by *** are marked by the expression of the lineage determinants Sox10 and Olig2 and arise from oligodendrocyte precursor cells(OPCs)during embryonal *** the majority of OPCs differentiate into mature oligodendrocytes when nearby axonal segments require myelination,a small subpopulation of OPCs persist as a progenitor ***,the timing of myelination and maintenance of the OPC pool both need to be precisely *** transcription factors either positively or negatively affect oligodendrocyte differentiation and maintenance of the OPC pool as components of a complex gene regulatory network(reviewed in Sock and Wegner,2021).Network activity is additionally influenced by extracellular signaling molecules that bind to receptors on the oligodendroglial cell surface and activate intracellular signaling *** the receptors are linked to the network is poorly understood so far,but pivotal to understanding the overall regulation of central nervous system(CNS)myelination in response to environmental *** insights were recently gained for Gpr37(Schmidt et al.,2024),a G-protein coupled receptor(GPCR)with known relevance in differentiating oligodendrocytes(Yang et al,2016).

关键词： gained insulation conduction

Translational machinery and translation regulation in axon regeneration

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Neural Regeneration Research 2025年第5期20卷 1392-1394页

作者： Homaira Nawabi Stephane Belin Univ.Grenoble Alpes InsermU1216Grenoble Institut NeurosciencesGrenobleFrance

Over the centuries,the regeneration field has been puzzled by the dual response of the central nervous system(CNS-brain,spinal cord,cranial nervesⅠandⅡ)and the peripheral nervous system(PNS that refers to all the nerves that innervate muscles,skin,organs,bones among others).Even Ramon y Cajal had noticed that an injury to the PNS often leads to axon regrowth,in contrast to the CNS.

关键词： nerves organs muscles

Evaluation of the Burnout of Caregivers of institut de Cancérologie d’Akanda

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Psycho-Oncologie 2023年第4期17卷 267-273页

作者： A.C.Filankembo Kava B.C.Ndjengue Bengono P.L.Nzamba Bissielou C.Nziengui Tirogo A.Kabena T.Mpami E.Belembaogo institut de cancérologie d’Akanda Libreville3000Gabon

Aim:Oncologists are particularly prone to developing burnout syndrome due to the demanding task of caring for cancer *** and incorrectly managed,burnout can have a negative impact on professional *** objective of the study is to measure the frequency of burnout among nursing staff at the institut de Cancérologie d’Akanda(ICA)and to assess the main risk ***:We conducted a cross-sectional study at the ICA during the month of January *** was assessed using the Maslach Burnout Inventory(MBI).Results:Between the 42 participants,there was a female predominance(57.1%)with a male to female sex ratio of *** mean age was 39.57±8.13 *** represented more than half of the sample(52.5%).The average years of service at the ICA was 6.30±4.80 *** emotional exhaustion was found in 35.7%of *** for severe depersonalization and severe loss of achievement,they were found in 14.3%and 31.0%of participants,*** burnout was found in 14.3%of *** was a significant association between emotional exhaustion,acts of violence and family support(p=0.031;p=0.042).Subjects who are victims of acts of violence are 5 times more likely to develop severe emotional exhaustion than subjects who are not *** with family support had an 82.6%reduced risk of developing severe emotional *** was no statistically significant association between the socio-demographic or professional variables of the sample and depersonalization as well as the loss of professional ***:Burnout is relatively common at the *** is important to be able to identify it in order to prevent the harmful effects it can have on the physical and mental health of staff,which may be responsible for a negative impact on the functioning of the service and the care of patients.A plea must be made against the director in order to set up awareness campaigns for the identification of the disorder a

关键词： Burnout emotional exhaustion depersonalization personal accomplishment

Impact of drops on Non-wetting Biomimetic Surfaces

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Journal of Bionic Engineering 2009年第4期6卷 330-334页

作者： Alain Merlen Philippe Brunet institut d'electronique de Microelectronique et Nanotechnologie IEMN Universite des sciences et technologies de Lille1UMR CNRS 8520Avenue Poincare BP 6006959652 Villeneuve d'Ascq cedexFrance

We have carried out an experimental study of liquid drop impact on superhydrophobic substrates covered by a carpet of chemically coated *** micro-structure of the surface is similar to some biological ones(Lotus leaf for example).In this situation the contact angle can then be considered as equal to 180 degrees,with no *** to its initial inertia,the drop experiences a flattening phase after it hits the surface,taking the shape of a *** it reaches its maximal lateral extension,the drop begins to retract and bounces *** have extracted the lateral extension of the drop,and we propose a model that explains the *** find a limit initial velocity beyond which the drop protrudes into the nano-wire *** discuss the relevance of practical issues in terms of self-cleaning surfaces or spray-cooling.

关键词： superhydrophobic surfaces drop impact

Central role of altered phosphodiesterase 2-dependent signaling in the pathophysiology of cognition-based brain disorders

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Neural Regeneration Research 2025年第8期20卷 2302-2303页

作者： Asma Boulksibat Alessandra Tempio Barbara Bardoni institut de Pharmacologie Moléculaire et Cellulaire CNRS UMR7275Inserm U1323ValbonneFrance

The second messengers 3',5'-cyclic adenosine monophosphate(cAMP)and 3',5'-cyclic guanosine monophosphate(cGMP)modulate molecular pathways that are involved in a large variety of cellular *** the brain,these processes include neurogenesis,neuronal differentiation,activation and function of microglia,and synaptic plasticity,finally resulting in memory formation.

关键词： formation processes finally