检索结果-南通市图书馆

Biocompatibility of iron carbide and detection of metals ions signaling proteomic analysis via HPLC/ESl-Orbitrap

Nano Research 2017年第6期10卷 1912-1923页

作者： Murtaza Hasan Wenlong Yang Yanmin Ju Xin Chu Yun Wang Yulin Deng Nasir Mahmood Yanglong Hou Department of Materials Science and engineering College of Engineering Peking University Beijing 700871 China School of Life Sciences Beijing Institu te of Technology Beijing 100081 China

Recently, magnetic nanopartides （NPs） have been extensively used in food industry and biomedical treatments. However, the biocompatibility mechanism on expression proteomics, before consideration of magnetic NPs for clinical application, has not yet been fully elucidated. Therefore, this study was undertaken to identify potential biomarkers of metal ion signaling proteins in human cervical cancer cell line （HeLa） cells. Here, we report the in vitro investigations of the cell cycle response and significant changes in protein abundance of HeLa cells when exposed to self-tailored hydrophilic Fe2C NPs. The comparative proteomic approach based on 180 labeling coupled with high performance liquid chromatography/ electrospray ionization with ion trap mass analyzer （HPLC/ESI-Orbitrap） was applied, and 394 proteins were identified. There were 46 significantly differentiated proteins based on the specific metal ion signaling response. Among them, 60S ribosomal protein L37a, serine/arginine-rich splicing factor 7, calmodulin, and calumenin were downregulated, whereas transketolase was overexpressed. Functional interaction network of Fe2C-regulated proteins was successfully created by the STRING algorithm to show the strong interactions between proteins. This work will not only help to understand the molecular mechanism of metal ion signaling proteins that can potentially be used to develop therapeutic protocols for diagnosis of diseases but also give direction for tailoring biocompatible magnetic NPs.

关键词： biocompatibility,^18O labeling magnetic nanoparticles proteomic analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Total Ionization Dose Effects on Charge Storage Capability of Al2O3/HfO2/Al2O3-Based Charge Trapping Memory Cell

引用

Chinese Physics Letters 2018年第11期35卷 86-89页

作者： Yan-Nan Xu Jin-Shun Bi Gao-Bo Xu Bo Li Kai Xi Ming Liu Hai-Bin Wang Li Luo institu te of Microelectronics Chinese Academy of SciencesBeijing 100029 University of Chinese Academy of Sciences Beijing 100049 School of lnternet of Things engineering HoHai UniversityChangzhou 213022 Beijing Jiaotong University Beijing 100044

Because of the discrete charge storage mechanism, charge trapping memory（CTM） technique is a good candidate for aerospace and military missions. The total ionization dose（TID） effects on CTM cells with Al2O3/HfO2/Al2O3（AHA） high-k gate stack structure under in-situ 10 keV x-rays are studied. The C-V characteristics at different radiation doses demonstrate that charge stored in the device continues to be leaked away during the irradiation,thereby inducing the shift of flat band voltage（V（fb））. The dc memory window shows insignificant changes, suggesting the existence of good P/E ability. Furthermore, the physical mechanisms of TID induced radiation damages in AHA-based CTM are analyzed.

关键词： AHA Total Ionization Dose Effects on Charge Storage Capability of Al2O3/HfO2/Al2O3-Based Charge Trapping Memory Cell Al

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Formation of Nitride Cu3N by MeV N-Ion Implantation into Cu

引用

Chinese Physics Letters 1991年第10期8卷 525-528页

作者： CUI Fuzhai A.M.Vredenberg R.de Reus F.W.Saris Department of Materials Science and engineering Tsinghua.Universityf Beijing 100084 FOM-institu£e for Atomic and Molecular Physics Kruislaan 4071098 SJ AmsterdamThe Netherlands

Experimental evidences are presented to show the formation of jiiCride,Cu3N,in pure Cu sample by N-ion *** result is obtained in the case of MeV ion *** experiments showed that this compound can not be formed by N-ion implantation into Cu at incident energy of about 100keV,This Ending indicates there exist certain difFerences in phase forma-tion by ion implcLntation at the two energies.

关键词： implantation pure incident

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Decision support for integrated river basin management—Scientific research challenges

引用

Science China Earth Sciences 2015年第1期58卷 16-24页

作者： CAI XiMing Landon MARSTON GE YingChun Ven te Chow Hydrosystems Laboratory Department of Civil and Environmental EngineeringUniversity of Illinois at Urbana-Champaign Cold and Arid Regions Environmental and engineering Research institute Chinese Academy of Sciences

Integrated River Basin Management(IRBM)has been a long discussed way to sustainably manage water and land resources;yet,very few examples of effective IRBM are found because there is a lack of sufficient scientific support,as well as institutional accommodation,to successfully implement *** paper overviews the major challenges with IRBM,the promising scientific approaches for the implementation of IRBM,and the areas of needed research,with considerable issues and experiences from *** is expected that novel research will draw together disparate disciplines into an integrated scientific framework,upon which better modeling tools,stakeholder involvement,and decision-making support can be ***-edge new technologies will bring ideas of IRBM forward to theory and finally to *** paper will prompt scientists to undertake research to fill in the gaps in the current IRBM knowledge base and provide practitioners guidance on how to incorporate scientifically based information within the IRBM decision process.

关键词： integrated river basin management scientific framework decision support China

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Overview of Organs-on-Chips Based on Deep Learning

引用

Research 2022年第2期2022卷 141-160页

作者： Jintao Li Jie Chen Hua Bai Haiwei Wang Shiping Hao Yang Ding Bo Peng Jing Zhang Lin Li Wei Huang Frontiers Science Center for Flexible Eletronrics Xi'an Institu te of Flexible Electronics(IFE)and Xr'an Institute of Biomedical Materials EngineeringNorthwesterm Polytechnical UniversityXi'an 710072China Key Laboratory of Ietlieant Computing and Signal Processing of Minsry of Educaton School of Electronics and Information EngineeringAnhui UriversityHefei 230601China 38th Research institute of China Eilectronics technology Grouep Corporation Hiefei 230088 China Collge of Biomedical Engimeering Sichuan UntiversityChengdu 610065China Key Laboratory of Flexible Elecronics(KLOFE)and institute of Advanced Materials(IAM)Nanjing tech University(Nanjingtech)J Nanjing 211800 China

Microfluidic-based organs-on-chips(OoCs)are a rapidly developing technology in biomedical and chemical research and have emerged as one of the most advanced and promising in vitro *** miniaturization,stimulated tissue mechanical *** microenvironment of OoCs offer unique properties for biomedical ***,the large amount of data generated by the high parallelization of OoC systems has grown far beyond the scope of manual analysis by researchers with biomedical *** learning,an emerging area of research in the field of machine learning,can automatically mine the inherent characteristics and laws of"big data"and has achieved remarkable applications in computer vision,speech recognition,and natural language *** integration of deep learning in OoCs is an emerging field that holds enormous potential for drug development,disease modeling,and personalized *** review bricfly describes the basic concepts and mechanisms of microfluidics and deep learning and summarizes their successful *** then analyze thecombination of OoCs and deep learning for image digitization,data analysis,and ***,the problems faced in current applications are discussed,and future perspectives and suggestions are provided to further strengthen this integration.

关键词： Deep holds beyond

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Low threshold random lasing in dye-doped and strongly disordered chiral liquid crystals

引用

Photonics Research 2020年第5期8卷 642-647页

作者： SHAOHUA GAO JIAYI WANG WENHUA LI XUANYI YU XINZHENG ZHANG XIAO SONG ANDREY ILJIN IRENA DREVENSEK-OLENIK ROMANO A.RUPP JINGJUN XU The MOE Key Laboratory of Weak-Light Nonlinear Photonics TEDA Institute of Applied Physics and School of PhysicsNankai UniversityTianjin 300457China institu te of optoelectronic engineering College of Physics&OptoelectronicsTaiyuan University of TechnologyTaiyuan 030024China Synergetic Innovation Center of Chemical Science and engineering Tianjin 300071China institute of Physics National Academy of Sciences of UkraineProspect Nauki 46Kiev 03028Ukraine Faculty of Mathematics and Physics University of Ljubljana and Department of Complex MatterJ.Stefan InstituteLjubljanaSlovenia Faculty of Physics Vienna UniversityBoltzmanngasse 5A-1090 WienAustria

Random lasing was experimentally investigated in pyrromethene 597-doped strongly disordered chiral liquid crystals (CLCs) composed of the nematic liquid crystal SLC1717 and the chiral agent CB15. The concentration of the chiral agent tuned the bandgap, and disordered CLC microdomains were achieved by fast quenching of the mixture from the isotropic to the cholesteric phase. Random lasing and band edge lasing were observed synchronously, and their behavior changed with the spectral location of the bandgap. The emission band for band edge lasing shifted with the change of the bandgap, while the emission band for random lasing remained practically constant. The results show that the threshold for random lasing sharply decreases if the CLC selective reflection band overlaps with the fluorescence peak of the dye molecules and if the band edge coincides at the same time with the excitation wavelength.

关键词： lasing random dye

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

On the modeling of viscous incompressible flows with smoothed particle hydrodynamics

引用

Journal of Hydrodynamics 2016年第5期28卷 731-745页

作者：刘谋斌李上明 College of engineering Peking University institute of Ocean Research Peking University State Key Laboratory for Turbulence and Complex systems Peking University institute of Systems engineering China Academy of Engineering Physics (CAEP)

Smoothed particle hydrodynamics （SPH） is a Lagrangian, meshfree particle method and has been widely applied to diffe- rent areas in engineering and science. Since its original extension to modeling free surface flows by Monaghan in 1994, SPH has been gradually developed into an attractive approach for modeling viscous incompressible fluid flows. This paper presents an overview on the recent progresses of SPH in modeling viscous incompressible flows in four major aspects which are closely related to the computational accuracy of SPH simulations. The advantages and disadvantages of different SPH particle approximation sche- mes, pressure field solution approaches, solid boundary treatment algorithms and particle adapting algorithms are described and analyzed. Some new perspectives and fuRtre trends in SPH modeling of viscous incompressible flows are discussed.

关键词： smoothed particle hydrodynamics (SPH) viscous incompressible flow free surface flow fluid-structure interaction(FSI)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Two-dimensional MXene hollow fiber membrane for divalent ions exclusion from water

引用

Chinese Journal of Chemical engineering 2022年第1期35卷 260-266页

作者： Guozhen Liu Yanan Guo Baochun Meng Zhenggang Wang Gongping Liu Wanqin Jin State Key Laboratory of Materials-Oriented Chemical engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China

Two-dimensional material membranes with fast transport channels and versatile chemical functionality are promising for molecular ***,for the first time,we reported design and engineering of two-dimensional Ti_(3)C_(2)Tx MXene(called transition metal carbides and nitrides)membranes supported on asymmetric polymeric hollow fiber substrate for water *** membrane morphology,physicochemical properties and ions exclusion performance were systematically *** results demonstrated that surface hydrophilicity and electrostatic repulsion and size sieving effect of interlayer channels synergistically endowed the MXene hollow fiber membrane with fast water permeation and efficient rejection of divalent ions during nanofiltration process.

关键词： Two-dimensional material MXene membranes Hollow fiber Desalination Nanofiltration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Measurement and analysis of soil nitrogen and organic matter content using near-infrared spectroscopy techniques

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2005年第11期6卷 1081-1086页

作者：何勇宋海燕 PEREIRA Annia García GóMEZ Antihus Hernández School of Biosystems engineering and Food Science Zhejiang University

Near infrared reflectance （N1R） spectroscopy is as a rapid, convenient and simple nondestructive technique useful for quantifying several soil properties. This method was used to estimate nitrogen （N） and organic matter （OM） content in a soil of Zhejiang Province, Hangzhou County. A total of 125 soil samples were taken from the field. Ninety-five samples spectra were used during the calibration and cross validation stage. Thirty samples spectra were used to predict N and OM concentration. NIR spectra of these samples were correlated using partial least square regression. The regression coefficients between measured and predicted values of N and OM was 0.92 and 0.93, and SEP （standard error of prediction） were 3.28 and 0.06, respectively, which showed that NIR method had potential to accurately predict these constituents in this soil. The results showed that NIR spectroscopy could be a good tool for precision farming application.

关键词： NIR spectroscopy Partial least square Precision farming Soil spatial variability Nitrogen Organic matter

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An injectable curcumin-releasing organohydrogel with non-drying property and high mechanical stability at low-temperature for expe dite d skin wound care

引用

Journal of Materials Science & technology 2023年第2期133卷 123-134页

作者： Kang Wu Qiang Yang Lin Zhang Pengcheng Xu Xiexing Wu Huilin Yang Huan Zhou Xiao Lin Lei Yang College of Chemistry Chemical Engineering and Materials ScienceOrthopaedic InstituteDepartment of Orthopaedic SurgeryThe First Affiliated HospitalSoochow UniversitySuzhou 215031China Center for Health Sciences and engineering(CHSE) School of Health Sciences and Biomedical EngineeringHebei University of TechnologyTianjin 300130China Department of Minimally Invasive Spine Surgery Tianjin HospitalTianjin 300211China

Although hydrogels have demonstrated great potential as new wound dressing materials,their instability in shape and/or mechanical characteristics due to water loss or freezing remains a shortcoming for wound care ***,a novel injectable organohydrogel(IOH)of physically crosslinked polyvinyl alco-hol/glycerol that possesses non-drying capability and high stability at low temperature was developed for wound *** has a skin-like stiffness(G’,∼280 Pa),high injectability,self-healing capability,high water-vapor transmission rate,and bacterial inhibitory *** exhibits high shape and mechanical stabilities after curing at 37°C and 50%relative humidity for 7 days or after curing at-20°C for 1 *** addition,glycerol in IOH enabled an efficient loading and release of water-insoluble curcumin,a well-known anti-bacterial and anti-inflammation *** curcumin-releasing IOH(Cur-IOH)demonstrated significantly enhanced anti-bacterial performance compared to IOH or curcumin-loading polyvinyl alco-hol *** importantly,Cur-IOH could accelerate wound healing in a murine full-thickness skin defect wound model,revealing improved wound contraction,collagen deposition,angiogenesis,and epi-dermis *** study demonstrates the great potential of organohydrogel for the reparation of severe wounds and Cur-IOH as a new type of injectable wound healing material.

关键词： Wound dressing Organohydrogel Non-drying Stability Curcumin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：