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Contrast-enhanced harmonic endoscopic ultrasound imaging: Basic principles, present situation and future perspectives

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World Journal of Gastroenterology 2014年第42期20卷 15549-15563页

作者： María-Victoria Alvarez-Sánchez Bertrand Napoléon Department of Gastroenterology H?pital Privé Jean Mermoz Department of Gastroenterology Complejo Hospitalario de Pontevedra

Over the last decade, the development of stabilised microbubble contrast agents and improvements in available ultrasonic equipment, such as harmonic imaging, have enabled us to display microbubble enhancements on a greyscale with optimal contrast and spatial resolution. Recent technological advances made contrast harmonic technology available for endoscopic ultrasound(EUS) for the first time in 2008. Thus, the evaluation of microcirculation is now feasible with EUS, prompting the evolution of contrast-enhanced EUS from vascular imaging to images of the perfused tissue. Although the relevant experience is still preliminary, several reports have highlighted contrast-enhanced harmonic EUS(CHEUS) as a promising noninvasive method to visualise and characterise lesions and to differentiate benign from malignant focal lesions. Even if histology remains the gold standard, the combination of CH-EUS and EUS fine needle aspiration(EUS-FNA) can not only render EUS more accurate but may also assist physicians inmaking decisions when EUS-FNA is inconclusive,increasing the yield of EUS-FNA by guiding the puncture with simultaneous imaging of the *** development of CH-EUS has also opened up exciting possibilities in other research areas,including monitoring responses to anticancer chemotherapy or to ethanolinduced pancreatic tissue ablation,anticancer therapies based on ultrasound-triggered drug and gene delivery,and therapeutic adjuvants by contrast ultrasound-induced *** harmonic imaging is gaining popularity because of its efficacy,simplicity and noninvasive nature,and many expectations are currently resting on this *** its potential is confirmed in the near future,contrast harmonic imaging will become a standard practice in EUS.

关键词： Microbubbles Contrast agents Contrast-enhanced harmonic endoscopic ultrasound Pancreatic tumour Gastrointestinal submucosal tumour

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Postoperative pain due to an occult spinal infection:A case report

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World Journal of Clinical Cases 2021年第15期9卷 3637-3643页

作者： Michiel Frederik Vande Kerckhove Vincent Fiere Thais Dutra Vieira Sami Bahroun Marc Szadkowski Henrid'Astorg Centre Orthopédique Santy Hopital PrivéJean MermozRamsay-Générale de SantéLyonFrance

BACKGROUND A high degree of vigilance is warranted for a spinal infection,particularly in a patient who has undergone an invasive procedure such as a spinal *** average delay in diagnosing a spinal infection is 2-4 *** our patient,the diagnosis of a spinal infection was delayed by 1.5 *** SUMMARY A 60-year-old male patient with a 1-year history of right-sided lumbar radicular pain failed conservative *** weeks to prior to surgery he received a spinal injection,which was followed by increasing lumbar radicular pain,weight loss and *** went unnoticed and surgery took place with right-sided L4-L5 combined microdiscectomy and foraminotomy via a posterior *** day after surgery,the patient developed left-sided lumbar radicular *** cultures grew Staphylococcus aureus(***).Magnetic resonance imaging showed inflammatory aberrations,revealing septic arthritis of the left-sided L4/L5 facet joint as the probable *** surgery took place and *** was isolated from bacteriological *** patient received postoperative antibiotic treatment,which completely eradicated the *** The development of postoperative lower back pain and/or lumbar radicular pain can be a sign of a spinal infection.A thorough clinical and laboratory work-up is essential in the preoperative evaluation of patients with spinal pain.

关键词： Arthritis Septic Lumbar region Disc herniated Spinal injections Case report

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Genome scan of pigmentation traits in Friesian-Jersey crossbred cattle

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Journal of Genetics and Genomics 2009年第11期36卷 661-666页

作者： Lin Liu Bevin Harris Mike Keehan Yuan Zhang Livestock Improvement Corporation Priv. Bag 3016 Hamilton 3240 New Zealand Beijing 100193 China College of Animal Science and Technology China Agricultural University Beijing 100193 China

Pigmentation traits expressed in animals are visual characteristics that allow us to distinguish between breeds and between strains within breed. The objective of this study was to map quantitative trait loci （QTLs） affecting the pigmentation traits in approximately 800 F2 grand daughter dairy cattle from a Holstein-Friesian and Jersey cross breed cattle. Traits analyzed included pigmentation phenotypes on the body, teat and hoop. The phenoypes were collected from digital photos or visual inspection of live animals. QTL mapping was implemented using half-sib and line-of-descent inheritance models. Our analysis initially detected a number of significant QTLs on chromosomes： 2, 6, 13, 15, 18 and 22. The significant QTLs were divided into two groups： one group influencing the pigmentation color and the other group affecting the absence or level of pigmentation. The most significant QTL peaks were observed on Bovine taurus autosome 18 （BTA18） close to melanocortin 1 receptor （MC1R） for the color traits, on BTA6 close to the receptor tyrosine kinase （K/T） and BTA22 close to microphthalmia-associated transcription factor （M/TF） gene for the spotting traits. Association studies were conducted for candidate regions or genes known to affect pigmentation in dairy cattle.

关键词： genome scan pigmentation trait QTL dairy cattle

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The anthocyanin's role on the food metabolic pathways,color and drying processes:An experimental and theoretical approach

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Food Bioscience 2022年第3期47卷 91-110页

作者： Sandra Peñaloza Cornelio Delesma Jesús Muñiz López-Ortiz A. Instituto de Energías Renovables Universidad Nacional Autónoma de MéxicoPriv.Xochicalco s/nCol.CentroTemixco62580MorelosMexico

This review is intended to cover the works related to the anthocyanin behavior in food that is subjected to *** experimental and theoretical results available in scientific literature are *** increase in anthocyanin concentration has been observed upon thermal ***,a conclusive explanation is still *** accessible studies suggest an increase in concentration during maturations,which could be related to the enzymatic *** possible enzymes involved in such a procedure have also been covered,including their role played in the *** possible activation mechanisms and the related factors such as temperature,pH,oxygen contents and the presence of UV-light irradiation were also ***,the metabolic pathways were also explored including experimental evaluation and theoretical models based on atomistic methodologies such as density functional theory(DFT).This review is aimed to provide a comprehensive overview of the probable mechanisms behind the increase of anthocyanin concentration during drying.

关键词： Anthocyanin Metabolic pathway PAL CHS UFGT HPLC Theoretical model

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Influence of acid and alkaline sources on optical, structural and photovoltaic properties of CdSe nanoparticles precipitated from aqueous solution

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Frontiers of Materials Science 2016年第2期10卷 168-177页

作者： C. Selene CORIA-MONROY Merida SOTELO-LERMA Hailin HU Instituto de Energias Renovables Universidad Nacional Autonoma de Mexico (UNAM) Priv. Xochicalco S/N 62580 Temixco Morelos Mexico Universidad de Sonora Blvd. Luis Encinas y Rosales S/N Col. Centro Hermosillo Sonora Mexico

CdSe is a widely researched material for photovoltaic applications. One of the most important parameters of the synthesis is the pH value, since it determines the kinetics and the mechanism of the reaction and in consequence, the optical and morphological properties of the products. We present the synthesis of CdSe in solution with strict control of pH and the comparison of ammonia and KOH as alkaline sources and diluted HCI as acid medium. CdSe formation was monitored with photoluminescence emission spectra （main peak in 490 nm, bandgap of CdSe nanoparticles）. XRD patterns indicated that CdSe nanoparticles are mainly of cubic structure for ammonia and HCI, but the hexagonal planes appear with KOH. Product yield decreases with pH and also decreases with KOH at constant pH value since ammonia has a double function, as complexing agent and alkaline source. Changes in morphology were observed in SEM images as well with the different alkaline source. The effect of alkaline sources on photovoltaic performance of hybrid organic solar cells with CdSe and poly（3-hexylthio- phene） as active layers was clearly observed, indicating the importance of synthesis conditions on optoelectronic properties of promising semiconductor nanomaterials for solar cell applications.

关键词： CdSe optical properties morphological properties hybrid solar cells

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Diagnostic endoscopic ultrasonography:Assessment of safety and prevention of complications

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World Journal of Gastroenterology 2012年第34期18卷 4659-4676页

作者： Christian Jenssen Maria Victoria Alvarez-Sánchez Bertrand Napoléon Siegbert Faiss Department of Internal Medicine Krankenhaus M rkisch-Oderland GmbHD15344 StrausbergGermany Department of Gastroenterology and Hepatology Hopital Privé Jean MermozF69008 LyonFrance Department of Gastroenterology and Hepatology Asklepios Klinik BarmbekD22291 HamburgGermany

Endoscopic ultrasonography (EUS) has gained wide acceptance as an important, minimally invasive diagnostic tool in gastroenterology, pulmonology, visceral surgery and oncology. This review focuses on data regarding risks and complications of non-interventional diagnostic EUS and EUS-guided fine-needle biopsy (EUS-FNB). Measures to improve the safety of EUS und EUS-FNB will be discussed. Due to the specific mechanical properties of echoendoscopes in EUS, there is a low but noteworthy risk of perforation. To minimize this risk, endoscopists should be familiar with the specific features of their equipment and their patients' specific anatomical situations (e.g., tumor stenosis, diverticula). Most diagnostic EUS complications occur during EUS-FNB. Pain, acute pancreatitis, infection and bleeding are the primary adverse effects, occurring in 1% to 2% ofpatients. Only a few cases of needle tract seeding and peritoneal dissemination have been reported. The mortality associated with EUS and EUS-FNB is 0.02%. The risks associated with EUS-FNB are affected by endoscopist experience and target lesion. EUS-FNB of cystic lesions is associated with an increased risk of infection and hemorrhage. Peri-interventional antibiotics are recommended to prevent cyst infection. Adequate education and training, as well consideration of contraindications, are essential to minimize the risks of EUS and EUS-FNB. Restricting EUS-FNB only to patients in whom the cytopathological results may be expected to change the course of management is the best way of reducing the number of complications.

关键词： Endoscopic ultrasonography Endoscopic ul-trasonography-guided fine-needle biopsy Complications Contraindications Risk Safety Perforation Bleeding Infection Acute pancreatitis

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*** 私人化生活

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时尚北京 2010年第11期 94-96页

作者：沈亚欣 BE.priv

高级定制,似乎一直都是西方世界的独有名词,每年法国巴黎的高级定制发布更是一场视觉的飨宴,模特身着美轮美奂的服饰缓缓前进,仿若童话世界里的公主一般,美丽不可方物。然而,当中国经济开始腾飞之时,这个西方世界的神秘名词也悄然步入... 详细信息

高级定制,似乎一直都是西方世界的独有名词,每年法国巴黎的高级定制发布更是一场视觉的飨宴,模特身着美轮美奂的服饰缓缓前进,仿若童话世界里的公主一般,美丽不可方物。然而,当中国经济开始腾飞之时,这个西方世界的神秘名词也悄然步入了我们的生活,越来越多的中国服装企业开始将触角深入高级定制的领域。很难用言语形容心中对于***的喜爱之情,即使你说中国的高级定制还不成熟,我仍然相信像***这样的品牌是可以撑起中国高级定制的未来的,但倘若你依旧不信,就目听我娓娓道来。

关键词：高级定制 BE.priv 私人化

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STEAM-HEATED AND CONDENSATE WATERS OVER GEOTHERMAL PROSPECTS IN A VOLCANIC ARC SETTING(BANDA ARC ISLANDS,INDONESIA)

STEAM-HEATED AND CONDENSATE WATERS OVER GEOTHERMAL PROSPECTS...

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李四光倡导中国地热能开发利用40周年纪念大会暨中国地热发展研讨会

作者： Manfred P.Hochstein Jannes Simanjuntak Sayogi Sudarman University of Auckland SOE and IESEPriv.Bag 92019Auckland(NZ)

A reconnaissance study of ten selected high temperature systems along the Banda Arc Island chain showed that half of them discharge only steam heated waters and some acidic condensates with rather small flow *** neutral(pH) bi-carbonate and neutral and acidic sulphate waters were identified as‘shallow waters’ which in diagrams of K/Mg equilibrium temperature versus SiO content cluster together near the amorphous silica species *** by‘deeper fluids’ can be recognised by their large isotopic O and D shifts as found at Wayang Windu,our chosen reference system on Java,and at Mataloko on *** outflows(up to 400 kg/s) of acidic sulphate waters without anomalous isotopic signature have been found in the foothill region of two active volcanoes,at Nage in the Bajawa Field for ***(pH) NaCl waters are discharged near the toe of concealed, deep outflows of three liquid dominated systems on Flores and Alor Island;their silica content is controlled by equilibration with chalcedony.

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Hydrothermal alteration of the surface volcanic rocks at the Acoculco geothermal field,Mexico:a multi-parametric approach

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Acta Geochimica 2024年第6期43卷 1037-1053页

作者： America Yosiris García-Soto Kailasa Pandarinath ESantoyo Eduardo Gonzalez-Partida Instituto de Energías Renovables Universidad Nacional Autónoma de MéxicoPriv.Xochicalco s/no.Col.CentroApartado Postal 3462580 TemixcoMorelosMexico Centro de Geociencias UNAMApartado Postal 1-74276001 QuerétaroQuerétaroMexico

The studies on hydrothermal alteration-induced eff ects in surface and subsurface rocks provide useful information in the characterization and exploitation of a geothermal ***,these studies are based on traditional,and reliable methods like petrography(primary and secondary minerals,and grade of alteration),and geochemistry(mobility of elements,changes in mass and concentration of elements,and fluid inclusions).Recently,apart from these established methods,some methods based on the geochemical(Chemical Index of Alteration,CIA;Weathering Index of Parkar,WIP;Loss on Ignition,LOI;and Sulfur,S)and rock magnetic properties(magnetic susceptibility,χlf;and percentage frequency-dependent susceptibility,χfd%)are also being applied in the identification of whether a rock is an altered or a fresh *** Acoculco Geothermal Field(AGF),Mexico,is characterized by high temperature and very low permeability,and it is considered a promissory Enhanced Geothermal *** following changes are observed in the rocks as a result of an increase in hydrothermal alteration:(1)an increase in CIA,LOI,and S values,and a decrease in WIP;(2)an increase in quartz and quartz polymorph minerals(silicification),and clay minerals(argillization);and(3)decrease inχlf *** AGF,the most altered surface acid rocks are characterized by entirely quartz and its polymorphs,and clay *** present study also indicates the applicability of the binary plots of major elements(felsic vs mafic component)and rock magnetic parameters(χlf vs.χfd%).The rock withχfd%value of 2-10 andχlf value<0.5×10^(-6)m^(3) kg^(-1)indicate the presence of single domain and stable single domain grains,which in turn suggests that it is an altered *** methods are simple to apply,rapid,reliable,and have the potential to become eff ective tools for the identifi cation of hydrothermally altered rocks during the initial stage of geothermal exploration.

关键词： Geothermal fields Hydrothermal alteration Surface rocks Magnetic susceptibility Alteration indices

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Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves:A single-center experience

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World Journal of Cardiology 2016年第12期8卷 735-745页

作者： Fadi J Sawaya Marco Spaziano Thierry Lefèvre Andrew Roy Phillippe Garot Thomas Hovasse Antoinette Neylon Hakim Benamer Mauro Romano Thierry Unterseeh Marie-Claude Morice Bernard Chevalier Department of Cardiology Générale de SantéInstitut Cardiovasculaire Paris-Sud-Hopital Privé Jacques Cartier

AIM To investigate the clinical outcomes of transcatheter aortic valve implantation(TAVI) with the SAPIEN 3 transcatheter heart valve(S3-THV) vs the SAPIEN XT valve(XT-THV).METHODS We retrospectively analyzed 507 patients that underwent TAVI with the XT-THV and 283 patients that received the S3-THV at our institution between March 2010 and December *** Thirty-day mortality(3.5% vs 8.7%:OR=0.44,P=0.21) and 1-year mortality(25.7% vs 20.1%,P=0.55) were similar in the S3-THV and the XT-THV *** rates of both major vascular complication and paravalvular regurgitation(PVR)>1 were almost 4 times lower in the S3-THV group than the XT-THV group(major vascular complication: 2.8% vs 9.9%,P1: 2.4% vs 9.7%,P<0.0001).However,the rate of new pacemaker implantation was almost twice as high in the S3-THV group(17.3% vs 9.8%,P=0.03).In the S3 group,independent predictors of new permanent pacemaker were pre-procedural RBBB(OR=4.9:P=0.001),pre-procedural PR duration(OR=1.14,P=0.05) and device lack of coaxiality(OR=1.13:P=0.05) during *** The S3-THV is associated to lower rates of major vascular complications and PVR but higher rates of new pacemaker compared to the ***-optimal visualization of the S3-THV in relation to the aortic valvular complex during deployment is a predictor of new permanent pacemaker.

关键词： SAPIEN-3 valve Vascular complications Permanent pacemaker Lack of coaxiality Paravalvular regurgitation

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