检索结果-南通市图书馆

Observation of peripheral refraction in myopic anisometropia in young adults

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2023年第12期16卷 2082-2088页

作者： Yu-Qin Du Yue-Hua Zhou Ming-Wei Ding Ming-Xu Zhang Yu-Juan Guo Shan-Shan Ge Eye School of Chengdu University of TCM Ineye Hospital of Chengdu University of TCMChengdu 610036Sichuan ProvinceChina Beijing Ming Vision and Ophthalmology Beijing 100010China

AIM:To investigate the differences in retinal refraction difference values(RDVs)of adult patients with myopic anisometropia compared with those without myopic anisometropia,and to investigate the relationship between ocular biometric measurements and relative peripheral ***:This clinical observation study included 130 patients with myopia(-0.25 to-10.00 D)between October 2022 and January 2023 aged between 18 and *** patients were divided into anisometropia(n=63;difference in binocular anisometropia≥1.00 D)and non-anisometropia(n=67;difference in binocular anisometropia0.05).There was a negative correlation between SE and TRDV(r=-0.205,P=0.001),RDV-20-53(r=-0.281,-0.183,-0.176,P<0.05),RDV-superior(r=-0.251,P<0.001),and RDV-temporal(r=-0.230,P<0.001),a negative correlation between CYL and RDV-10-30(r=-0.147,-0.180

关键词： myopia anisometropia peripheral refraction multispectral refractive topography axial length

Therapeutic potential of pupilloplasty combined with phacomulsification and intraocular lens implantation against uveitis-induced cataract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2022年第10期15卷 1598-1603页

作者： Hui Lu Dou-Dou Chen Si-Quan Zhu Department of Ophthalmology Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Ophthalmology Ineye Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Ophthalmology Beijing Anzhen HospitalCapital Medical UniversityBeijing 100029China

AIM: To evaluate the therapeutic effect of pupilloplasty combined with phacomulsification and intraocular lens implantation(PPI) in uveitis-induced ***: Total 28 patients with uveitis-induced cataract were enrolled. Within 3 mo before the PPI, 7 cases accompanied with glaucoma maintained carteolol hydrochloride for lowering intraocular pressure, and 1 case maintained glucocorticoid for anti-inflammation. The baseline characteristics, treatment processes, and outcomes of enrolled cases were retrospectively analyzed. Hematoxylin and eosin(HE) staining was performed to reveal the histopathological changes of iris ***: Iris hemorrhage was the only intraoperative complication observed in 2 cases. After the surgery, normal intraocular pressure, right position of intraocular lens, and improved visual gain [best corrected visual acuity(BCVA)>0.5] were achieved. Postoperative keratic precipitates was observed in 2 cases, which was recovered within 1 wk. During the follow-up of 5-10 y, no recurrence of uveitis was found in 27 cases(96.43%). Uveitis only recurred in one case with the onset of ankylosing spondylitis. HE staining showed iris stroma(all samples), pigment cell hyperplasia in pigment epithelium(n=9) and stroma(n=19), inflammatory cell infiltration in iris(n=7), and neovascularization in iris surface(n=2).CONCLUSION: PPI improves the visual gain and prevents the long-term recurrence of uveitis in patients with uveitis-induced cataract, including those with preoperative intraocular pressure abnormality(glaucoma) and inflammation(active uveitis). Uveitis presents stroma atrophy, pigment cell hyperplasia, and inflammatory cell infiltration, even in a quiet state.

关键词： uveitis cataract glaucoma histopathology recurrence

Effect of etanercept on post-traumatic proliferative vitreoretinopathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2019年第5期12卷 731-738页

作者： Xiao-Feng Chen Mei Du Xiao-Hong Wang Hua Yan Department of Ophthalmology Tianjin Medical University General Hospital ineye hospital of Chengdu University of Traditional Chinese Medicine

AIM: To evaluate the safety and efficacy of intravitreal etanercept in the inhibiting of proliferative vitreoretinopathy(PVR) in a model of penetrating ocular injury. METHODS: Penetrating ocular injury on the retina of rabbit was induced, which was subsequently treated using 0.1 mL of sterile water or 0.1 m L of 12.5 mg/mL etanercept. The development of PVR was evaluated by fundus images, the B-scan, and the histopathology. The mRNA and protein expressions of tumor necrosis factor-α(TNF-α), transforming growth factor β(TGF-β) as well as connective tissue growth factor(CTGF) were examined at various time points after the etanercept injection with the reverse transcriptase-polymerase chain reaction(RT-PCR) and Western blotting, respectively. The safety of etanercept was evaluated by injection of 12.5 mg/mL etanercept into a normal rabbit eye without penetrating trauma. RESULTS: Clinical assessment and grading clearly demonstrated that the PVR formation was prevented in etanercept-treated animals, which was confirmed via fundus images, B-scan and histopathology. The RT-PCR and Western blotting showed increased mRNA and protein expression of TNF-α, TGF-β as well as CTGF in the retina of rabbits following penetrating ocular injury, and these factors were dramatically mitigated by ocular etanercept treatment. In addition, there was no adverse effect of etanercept intravitreal injection in normal eyes without penetrating trauma, it showed normal structure and histology. CONCLUSION: The etanercept is a potential therapy for inhibiting PVR development. To assess the clinic application of the etanercept in preventing PVR, further clinical studies are required.

关键词： etanercept/rh TNFR-Ig traumatic proliferative vitreoretinopathy TNF-α inhibitor/anti TNF-α rabbit

Comparison of uniform resampling and nonuniform sampling direct-reconstruction methods in k-space for FD-OCT

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2023年第5期16卷 93-106页

作者： Yanrong Yang Yun Dai Yuehua Zhou Yaliang Yang College of Ophthalmology Chengdu University of Traditional Chinese Medicine Chengdu 610075 P.R.China Institute of Optics and Electronics Chinese Academy of Sciences Chengdu 610209P.R.China Key Laboratory of Adaptive Optics Chinese Academy of Sciences Chengdu 610209P.R.China Key Laboratory of Sichuan Province Ophthalmopathy Prevention&Cure and Visual Function Protection with TCM Chengdu 610075 P.R.China ineye hospital of Chengdu University of TCM Chengdu 610075 P.R.China

The nonuniform distribution of interference spectrum in wavenumber k-space is a key issue to limit the imaging quality of Fourier-domain optical coherence tomography(FD-OCT).At present,the reconstruction quality at different depths among a variety of processing methods in k-space is still *** simulated and experimental interference spectra at different depths,the effects of common six processing methods including uniform resampling(linear interpolation(LI),cubic spline interpolation(CSI),time-domain interpolation(TDI),and K-B window convolution)and nonuniform sampling direct-reconstruction(Lomb periodogram(LP)and nonuniform discrete Fourier transform(NDFT))on the reconstruction quality of FD-OCT were quantitatively analyzed and compared in this *** results obtained by using simulated and experimental data were *** the experimental results,the averaged peak intensity,axial resolution,and signal-to-noise ratio(SNR)of NDFT at depth from 0.5 to 3.0mm were improved by about 1.9 dB,1.4 times,and 11.8 dB,respectively,compared to the averaged indices of all the uniform resampling methods at all ***,the improvements of the above three indices of LP were 2.0 dB,1.4 times,and 11.7 dB,*** analysis method and the results obtained in this work are helpful to select an appropriate processing method in k-space,so as to improve the imaging quality of FD-OCT.

关键词： Optical coherence tomography signal processing uniform resampling nonuniform sampling direct-reconstruction reconstruction quality.

Qiming granule in treating type 2 diabetic kidney disease patients:study protocol for a randomized controlled trial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Traditional Medicine Research 2021年第1期6卷 7-15页

作者： Jian Huo Jun-Guo Duan Xue-Jing Lu Fu-Wen Zhang Wen-Yuan Jian Jia-Qing Sui Jia-Ling Ai Li-Sha Liu College of Ophthalmology Chengdu University of Traditional Chinese MedicineChengdu 610075China Chengdu Women’s and Children’s Central hospital School of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 611731China ineye hospital Chengdu 610084China

Background:Diabetic kidney disease(DKD)is a chronic renal microvascular complication associated with abnormal glucose *** to traditional Chinese medicine(TCM)theory,Qi and Yin deficiency with blood stasis(the name of TCM symptoms,its main clinical features are fatigue,dry mouth,red or pale tongue,weak pulse,etc.)is the primary TCM syndrome of DKD,and Qiming granule(QMG)is suitable for the treatment of Qi and Yin deficiency with blood stasis *** view of this,we designed a randomized controlled trial to assess whether QMG is efficacious and safe in treating DKD ***:This protocol is for a randomized,double-blind,placebo-controlled,parallel group,six-centre clinical trial.A total of 180 participants will be randomized into the QMG group or placebo group,with a 1:1 *** study will last for 50 weeks,including a 2-week run-in period,24 weeks of intervention,and 24 weeks of *** experimental intervention will be QMG,and the control intervention will be a *** primary outcome will be the 24h urinary albumin excretion ratio and the change in the albumin-to-creatinine *** secondary outcome will be evaluation of renal function,fundus changes,management of blood lipids,TCM symptom improvement and safety *** events will be recorded during the ***:This study is a randomized controlled trial to test the effectiveness and safety of QMG for DKD *** findings of this study will help to provide evidence-based recommendations in treating DKD *** registration:Chinese Clinical Trial Registry,*** 23 December 2012.

关键词： Diabetic kidney disease Qiming granule Traditional Chinese medicine Randomized controlled trial

Clinical evidence and potential mechanisms of Chinese medicines for the treatment of diabetic retinopathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Traditional Medicine Research 2018年第2期3卷 42-53页

作者： Jian Huo Ke-Yu Zhu Qian Yang Wen Liu Jun-Guo Duan Academy of Ophthalmology Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China Chengdu University of Traditional Chinese Medicine Affiliated ineye hospital Chengdu Sichuan China

糖尿病视网膜病变是导致患者视力损害和失明的主要原因之一.目前,由于抗VEGF制剂、类固醇激素、激光光凝和玻璃体手术在治疗糖尿病视网膜病变中的局限性,使得人们越来越重视中医药在糖尿病视网膜病变中的治疗作用.本文就中药配方（包括... 详细信息

糖尿病视网膜病变是导致患者视力损害和失明的主要原因之一.目前,由于抗VEGF制剂、类固醇激素、激光光凝和玻璃体手术在治疗糖尿病视网膜病变中的局限性,使得人们越来越重视中医药在糖尿病视网膜病变中的治疗作用.本文就中药配方（包括复方制剂、专利药和古方）的组成及其特点,中药在糖尿病视网膜病变中临床应用及作用机制方面的研究进行综述.由于中药的复杂性,关于中药的作用机制、副作用以及药物之间的相互作用等方面的问题,需要进一步深入的研究.中医药可防止病变进一步发展和恶化,保护残余视力,延缓病变发展;在糖尿病视网膜病变的预防和治疗中存在显著优势.

关键词：糖尿病视网膜病变中医药配方中成药