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Artificial Intelligence in Agriculture 2021年第1期5卷 233-239页

作者： Mogens Graf Plessen MGP is an Independent Researcher

Within the context of in-field path planning this paper discusses freeformpath fitting for theminimisation of the number of transitions between headland path and interior laneswithin agricultural fields.This topic ismotivated by two observations.Due to crossings of tyre traces such transitions in practice often cause an increase of compacted area.Furthermore,for very tight angles between headland path and interior lanes undesired hairpin turnsmay becomenecessary due to the limited agility of in-field operating tractors.Byminimising the number of interior lanes both detrimental effects can be mitigated.The potential of minimising the number of interior lanes by freeform path fitting is evaluated on 10 non-convex real-world fields including obstacle areas,and compared to the more common technique of fitting straight interior lanes.

关键词： In-field path planning Freeform path fitting Agricultural logistics

Facing the 2020 pandemic: What does cyberbiosecurity want us to know to safeguard the future?

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Biosafety and Health 2021年第1期3卷 11-21页

作者： Siguna Mueller Multidisciplinary Independent ResearcherAustria

As the entire world is under the grip of the coronavirus disease 2019(COVID-19),and as many are eagerly trying to explain the origins of the virus and cause of the pandemic,it is imperative to place more attention on related potential biosafety risks.Biology and biotechnology have changed dramatically during the last ten years or so.Their reliance on digitization,automation,and their cyber-overlaps have created new vulnerabilities for unintended consequences and potentials for intended exploitation that are mostly under-appreciated.This study summarizes and elaborates on these new cyberbiosecurity challenges,(1)in terms of comprehending the evolving threat landscape and determining new risk potentials,(2)in developing adequate safeguarding measures,their validation and implementation,and(3)specific critical risks and consequences,many of them unique to the life-sciences.Drawing other's expertise and my previous work,this article reviews and critically interprets our current bio-economy situation.The goal is not to attribute causative aspects of past biosafety or biosecurity events,but to highlight the fact that the bioeconomy harbors unique features that have to be more critically assessed for their potential to unintentionally cause harm to human health or environment,or to be re-tasked with an intention to cause harm.It is concluded with recommendations that will need to be considered to help ensure converging and emerging biorisk challenges,in order to minimize vulnerabilities to the life-science enterprise,public health,and national security.

关键词： Laboratory safety Cyberbiosecurity Risk assessment Protective measures Convergence Biolabs of the future

Numerical three-dimensional modeling of earthen dam piping failure

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Water Science and Engineering 2024年第1期17卷 72-82页

作者： Zhengang Wang Independent Researcher HerndonVA 2017lUSA

A physically-based numerical three-dimensional earthen dam piping failure model is developed for homogeneous and zoned soil dams.This model is an erosion model,coupled with force/moment equilibrium analyses.Orifice flow and two-dimensional(2D)shallow water equations(SWE)are solved to simulate dam break flows at different breaching stages.Erosion rates of different soils with different construction compaction efforts are calculated using corresponding erosion formulae.The dam's real shape,soil properties,and surrounding area are programmed.Large outer 2D-SWE grids are used to control upstream and downstream hydraulic conditions and control the boundary conditions of orifice flow,and inner 2D-SWE flow is used to scour soil and perform force/moment equilibrium analyses.This model is validated using the European Commission IMPACT(Investigation of Extreme Flood Processes and Uncertainty)Test#5 in Norway,Teton Dam failure in Idaho,USA,and Quail Creek Dike failure in Utah,USA.All calculated peak outflows are within 10%errors of observed values.Simulation results show that,for a V-shaped dam like Teton Dam,a piping breach location at the abutment tends to result in a smaller peak breach outflow than the piping breach location at the dam's center;and if Teton Dam had broken from its center for internal erosion,a peak outflow of 117851 m'/s,which is 81%larger than the peak outflow of 65120 m3/s released from its right abutment,would have been released from Teton Dam.A lower piping inlet elevation tends to cause a faster/earlier piping breach than a higher piping inlet elevation.

关键词： 3D dam breach model 2D shallow water equations 3D slope stability analysis Piping failure Teton Dam Quail Creek Dike

Explicit Estimates for Solutions of Nonlinear Radiation-type Problems

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Acta Mathematica Sinica,English Series 2015年第7期31卷 1123-1140页

作者： Luisa CONSIGLIERI Independent Researcher Professor

We establish the existence of weak solutions of a nonlinear radiation-type boundary value problem for elliptic equation on divergence form with discontinuous leading coefficient. Quantitative estimates play a crucial role on the real applications. Our objective is the derivation of explicit expres- sions of the involved constants in the quantitative estimates, the so-called absolute or universal bounds. The dependence on the leading coefficient and on the size of the spatial domain is precise. This work shows that the expressions of those constants are not so elegant as we might expect.

关键词： Elliptic equation estimate regularity radiation-type boundary condition

The Relation between Regional Power Policies of Turkey and the Media Strategy of President Erdogan

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Asian Journal of Middle Eastern and Islamic Studies

Asian Journal of Middle Eastern and Islamic Studies 2023年第3期17卷 277-295页

作者： Melih Dincer Independent Researcher IstanbulTurkey

This research investigates the relation between regional power policies of Turkey and the media strategy of President Erdogan.After the coup attempt on July 15,2016,the Justice and Development Party started to implement regional power policies,which are focusing on security affairs.The political power fell into the hands of the President.Regional power policies are used as a legitimised as a tool for the transition to authoritarianism.The main purpose of this transition is to suppress dissident voices by controlling the media.In this article,I argue that President Erdogan uses regional power policies as a tool to control the national media.The President is trying to create the image of a world leader for himself by using the pro-government media companies.Turkey's of natural gas,the Libya issue and the NATO Summit in Madrid will be discussed in terms of media's perspectives.

关键词： Turkish foreign policy regional power the discourse of powerful Turkey domestic politics national media

The role of GRP81 lactate receptor in synaptic transmission regulation: does it enhance endocytosis?

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Neural Regeneration Research 2022年第12期17卷 2657-2658页

作者： Sergei V.Fedorovich Tatsiana V.Waseem Department of Biochemistry Belarusian State UniversityMinskBelarus Independent Researcher MinskBelarus

The brain is an expensive tissue in terms of energy consumption.It composes about 2%of body mass and consumes about 20%of all oxygen and calories(Fedorovich and Waseem,2018).For neurons,glucose is the primary energy substrate,although they are able to use ketone bodies,pyruvate and lactate(Fedorovich and Waseem,2018).All these compounds can be metabolized directly in the Krebs cycle,bypassing glycolysis.Hence,they are often termed non-glycolytic energy substrates.Out of all potential non-glycolytic substrates,lactate is the most physiological(Magistretti and Allaman,2018).Ketone bodies could reach concentrations in blood plasma and cerebrospinal fluid which are sufficient to meet metabolic demands of neurons only under specific non-physiological conditions,e.g.,ketogenic diet and starvation,or during suckling.In contrast,the normal plasma level of lactate is about 1.5 mM and can reach 20 mM during intensive physical exercise.

关键词： ketone glycol cycle

Nanotechnological approaches for counteracting multidrug resistance in cancer

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Cancer Drug Resistance 2020年第4期3卷 1003-1020页

作者： Chiara Martinelli Marco Biglietti Independent Researcher Como 22100Italy Independent Researcher Milan 20148Italy

Every year,cancer accounts for a vast portion of deaths worldwide.Established clinical protocols are based on chemotherapy,which,however,is not tumor-selective and produces a series of unbearable side effects in healthy tissues.As a consequence,multidrug resistance(MDR)can arise causing metastatic progression and disease relapse.Combination therapy has demonstrated limited responses in the treatment of MDR,mainly due to the different pharmacokinetic properties of administered drugs and to tumor heterogeneity,challenges that still need to be solved in a significant percentage of cancer patients.In this perspective,we briefly discuss the most relevant MDR mechanisms leading to therapy failure and we report the most advanced strategies adopted in the nanomedicine field for the design and evaluation of ad hoc nanocarriers.We present some emerging classes of nanocarriers developed to reverse MDR and discuss recent progress evidencing their limits and promises.

关键词： Multidrug resistance cancer nanotechnology nanomedicine nanocarriers targeted delivery

The Multipolar World and Small States:Emerging Perspectives in India-Kuwait Strategic Partnerships

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Asian Journal of Middle Eastern and Islamic Studies 2021年第2期15卷 289-308页

作者： Radhika Lakshminarayanan Independent Researcher based in Kuwait

In the twenty-first Century,small state partnerships are being realigned in the multipolar world.Addressing security concerns of small states,this paper reviews the prospects of strategic partnerships between small states and emerging powers.Contextualising from the historical relations between India and Kuwait,the paper analyses the dynamics of‘soft power’balancing within areas of mutual convergence.Further,the paper presents a future trajectory for small state partnerships with rising powers in an era of geo-economic interdependence.

关键词： Multipolar world small states India-Kuwait strategic partnerships alliances

Preserving Privacy of Software-Defined Networking Policies by Secure Multi-Party Computation

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Journal of Computer Science & Technology 2020年第4期35卷 863-874页

作者： Maryam Zarezadeh Hamid Mala Homa Khajeh Faculty of Computer Engineering University of IsfahanIsfahan ***Iran Independent Researcher Isfahan ***Iran

In software-defined networking(SDN),controllers are sinks of information such as network topology collected from switches.Organizations often like to protect their internal network topology and keep their network policies private.We borrow techniques from secure multi-party computation(SMC)to preserve the privacy of policies of SDN controllers about status of routers.On the other hand,the number of controllers is one of the most important concerns in scalability of SMC application in SDNs.To address this issue,we formulate an optimization problem to minimize the number of SDN controllers while considering their reliability in SMC operations.We use Non-Dominated Sorting Genetic Algorithm II(NSGA-II)to determine the optimal number of controllers,and simulate SMC for typical SDNs with this number of controllers.Simulation results show that applying the SMC technique to preserve the privacy of organization policies causes only a little delay in SDNs,which is completely justifiable by the privacy obtained.

关键词： software-defined networking (SDN) privacy secure multi-party computation (SMC) structure function multi-objective optimization

The Hard Problem of Consciousness from a Bio-Psychological Perspective

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Journal of Philosophy Study 2017年第11期7卷 579-594页

作者： Franz Klaus Jansen Independent Researcher