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Defence Technology（防务技术） 2024年第5期35卷 47-59页

作者： Alexandre Riot Enrico Panettieri Antonio Cosculluela marco montemurro Universite de Bordeaux Arts et Metiers Institute of TechnologyCNRSINRABordeaux INPHESAM UniversiteI2M UMR 5295F-33405 TalenceFrance French Atomic Energy Commission Route des GargailsCedexF-33114Le BarpFrance

modern additive manufacturing processes enable fabricating architected cellular materials of complex shape,which can be used for different *** them,lattice structures are increasingly used in applications requiring a compromise among lightness and suited mechanical properties,like improved energy absorption capacity and specific stiffness-to-weight and strength-to-weight ratios.A dedicated modeling strategy to assess the energy absorption capacity of lattice structures under uni-axial compression loading is presented in this *** numerical model is developed in a non-linear framework accounting for the strain rate effect on the mechanical responses of the lattice *** geometries,i.e.,cubic body centered cell,octet cell,rhombic-dodecahedron and truncated cuboctahedron 2+,are ***,the influence of the relative density of the representative volume element of each geometry,the strain-rate dependency of the bulk material and of the presence of the manufacturing process-induced geometrical imperfections on the energy absorption capacity of the lattice structure is *** main outcome of this study points out the importance of correctly integrating geometrical imperfections into the modeling strategy when shock absorption applications are aimed for.

关键词： Lattice structures Architected cellular materials Dynamic simulation Energy absorption Geometrical imperfection Additive manufacturing

Numerical Study of Semidiscrete Penalty Approach for Stabilizing Boussinesq System with Localized Feedback Control

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Annals of Applied mathematics 2024年第2期40卷 191-218页

作者： mejdi Azaiez Kevin Le Balc'h Universite de Bordeaux Bordeaux-INPI2M UMR5295F-33400TalenceFrance inria Sorbonne UniversiteUniversite de ParisCNRSLaboratoire Jacques-Louis LionsParisFrance

We investigate the numerical approximation for stabilizing the semidiscrete linearized Boussinesq system around an unstable stationary *** is attained through internal feedback controls applied to the velocity and temperature equations,localized within an arbitrary open *** study follows the framework presented in[14],considering the continuous linearized Boussinesq *** primary objective is to explore the penalizationbased approximation of the free divergence condition in the semidiscrete case and provide a numerical validation of these results in a two-dimensional setting.

关键词： Boussinesq system penalty method stabilization feedback control

Gut microbiome regulates inflammation and insulin resistance:a novel therapeutic target to improve insulin sensitivity

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Signal Transduction and Targeted Therapy 2024年第3期9卷 825-827页

作者： Dilvin Semo Holger Reinecke Rinesh Godfrey Vascular Signalling Molecular CardiologyDepartment of Cardiology I-Coronary and Peripheral Vascular DiseaseHeart FailureUniversity Hospital Münster48149 MünsterGermany

in a recent study published in Nature,Takeuchi et *** a multiomics strategy in humans to provide compelling evidence that increased carbohydrate metabolism by the gut microbiota contributes to insulin resistance(iR).The authors uncovered a previously unknown link between elevated gut monosaccharides and host inflammatory cytokines and suggest potential intervention opportunities to combat iR by targeting specific gut microbial species.

关键词： metabolism inflammation al.

On the Contribution of Wu Wen-Tsün to Algebraic Topology

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Journal of Systems Science & Complexity 2019年第1期32卷 3-36页

作者： BRASSELET Jean-Paul i2m (CNRS)-Aix-marseille University

The aim of this article is to present the contribution of Wu Wen-Tsün to Algebraic Topology and more precisely to the theory of characteristic classes. Several papers provide complete and welldocumented biography and academic career of Wu Wen-Tsün, in particular, Hudecek, 2014; O'Connor and Robertson, 2006; Wen-Tsün Wu's Academic Career, 2006; Selected works of Wen-Tsun Wu, *** author does not repeat the details provided in these papers concerning the Wu Wen-Tsün's bibliography, we will just mention people involved in the Wu Wen-Tsün's period in *** addition to Wu Wen-Tsün's papers, the Dieudonné's book(Dieudonné, 1960) provides an excellent presentation of main results of Wu Wen-Tsün in Algebraic and Differential Topology. The author will use and abuse of this book(and refer to) when *** the introduction, the author recalls mainly historical facts concerning the contribution of Wu Wen-Tsün to Algebraic Topology. The second section shows speci?cally the contribution of Wu WenTsün to the Stiefel-Whitney classes and introduces the third section, dealing with the(real) Wu *** author provides de?nition, properties as well as further developments and generalizations of the Wu classes. The fourth and ?fth sections are devoted to recent applications: in Cobordism theory and in mathematical Physics. The author notices that Wu classes have been used as well in other domains,in particular surgery theory(madsen and milgram, 1979). The last section concerns the complex Wu classes and shows that the more recent mather classes coincide with the previously de?ned complex Wu classes, that is a result from Zhou(1994)(see also Liu, 1996).This article is devoted to the contribution of Wu Wen-Tsün to the theory of Characteristic Classes,which coincides with his "French period"(1947–1951). However, speaking of Algebraic Topology, it is worthwhile to mention the important contribution of Wu Wen-Tsün to the Theory of realization of complexes or manifolds in Eucl

关键词： Algebraic topology characteristic class cobordism theory mathematical physics Wu Class

Analysis of cohesive particles mixing behavior in a twin-paddle blender:DEm and machine learning applications

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Particuology 2024年第7期90卷 350-363页

作者： Behrooz Jadidi mohammadreza Ebrahimi Farhad Ein-mozaffari Ali Lohi Department of Chemical Engineering Toronto Metropolitan University350 Victoria StreetToronto M5B 2K3Canada

This research paper presents a comprehensive discrete element method(DEm)examination of the mixing behaviors exhibited by cohesive particles within a twin-paddle blender.A comparative analysis between the simulation and experimental results revealed a relative error of 3.47%,demonstrating a strong agreement between the results from the experimental tests and the DEm *** main focus centers on systematically exploring how operational parameters,such as impeller rotational speed,blender's fill level,and particle mass ratio,influence the *** investigation also illustrates the significant influence of the mixing time on the mixing *** gain a deeper understanding of the DEm simulation findings,an analytical tool called multivariate polynomial regression in machine learning is *** method uncovers significant connections between the DEm results and the operational parameters,providing a more comprehensive insight into their *** multivariate polynomial regression model exhibited robust predictive performance,with a mean absolute percentage error of less than 3%for both the training and validation sets,indicating a slight deviation from actual *** model's precision was confirmed by low mean absolute error values of 0.0144(80%of the dataset in the training set)and 0.0183(20%of the dataset in the validation set).The study offers valuable insights into granular mixing behaviors,with implications for enhancing the efficiency and predictability of the mixing processes in various industrial applications.

关键词： machine learning Granular mixing Discrete element method mixing kinetics and mechanism Cohesive particles

mixing and matching SmXL proteins to fine-tune strigolactone responses

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molecular Plant 2024年第8期17卷 1167-1169页

作者： Jenna E.Hountalas Shelley Lumba Department of Cell&Systems Biology University of Toronto25 Willcocks StreetTorontoON M5S 3B2Canada Centre for the Analysis of Genome Evolution and Function University of Toronto25 Willcocks StreetTorontoON M5S 3B2Canada

A common mechanism in plant hormone signaling is hormonedependent degradation of downstream *** the case of strigolactone(SL)signaling,one group of SUPPRESSOR OF mORE AXiLLARY BRANCHES 2(mAX2)1-LiKE(SmXL)proteins undergoes hormone-dependent degradation,while another does not.A recent publication in molecular Plant by Li et al.(2024)illustrates that mixing and matching a SmXL resistant to SL degradation with a SmXL sensitive to SL degradation finely tunes SL *** phenomenon could reflect a naturally occurring negative transdominance,which is a dominantnegative effect arising not from a mutant allele of the same gene but rather from a different gene altogether(Veitia,2007).This trans-acting protein attenuates SL-dependent degradation of the SmXL *** findings have exciting implications for how different SmXL combinations could result in a gradient of SL responses.

关键词： complex. matching degradation

Bioinspired polysaccharide-based nanocomposite membranes with robust wet mechanical properties for guided bone regeneration

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National Science Review 2024年第3期11卷 215-226页

作者： Jian-Hong Xiao Zhen-Bang Zhang JiaHao Li Si-ming Chen Huai-Ling Gao YinXiu Liao Lu Chen ZiShuo Wang YiFan Lu YuanZhen Hou HengAn Wu DuoHong Zou Shu-Hong Yu Department of Chemistry New Cornerstone Science Laboratory Institute of Biomimetic Materials&Chemistry Anhui Engineering Laboratory of Biomimetic MaterialsDivision of Nanomaterials&Chemistry Hefei National Research Center for Physical Sciences at the Microscale University of Science and Technology of China Department of Dental implant Center Stomatologic Hospital and College Key Laboratory of Oral Diseases Research of Anhui Province Anhui Medical University CAS Key Laboratory of mechanical Behavior and Design of materials Department of Modern Mechanics CAS Center for Excellence in Complex System Mechanics University of Science and Technology of China Department of Oral Surgery College of Stomatology National Clinical Research Center for Oral DiseasesShanghai Key Laboratory of Stomatology Shanghai Research Institute of Stomatology Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine institute of innovative materials(i2m) Department of Chemistry Department of Materials Science and Engineering Southern University of Science and Technology

Polysaccharide-based membranes with excellent mechanical properties are highly desired. However, severe mechanical deterioration under wet conditions limits their biomedical applications. Here, inspired by the structural heterogeneity of strong yet hydrated biological materials, we propose a strategy based on heterogeneous crosslink-and-hydration（HCH） of a molecule/nano dual-scale network to fabricate polysaccharide-based nanocomposites with robust wet mechanical properties. The heterogeneity lies in that the crosslink-and-hydration occurs in the molecule-network while the stress-bearing nanofiber-network remains unaffected. As one demonstration, a membrane assembled by bacterial cellulose nanofiber-network and Ca2+-crosslinked and hydrated sodium alginate molecule-network is designed. Studies show that the crosslinked-and-hydrated molecule-network restricts water invasion and boosts stress transfer of the nanofiber-network by serving as interfibrous bridge. Overall, the molecule-network makes the membrane hydrated and flexible; the nanofiber-network as stress-bearing component provides strength and *** HCH dual-scale network featuring a cooperative effect stimulates the design of advanced biomaterials applied under wet conditions such as guided bone regeneration membranes.

关键词： bioinspiration heterogeneous crosslink-and-hydration dual-scale network nanocomposite membrane wet mechanical properties guided bone regeneration

Hypothalamic circuits and aging:keeping the circadian clock updated

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Neural Regeneration Research 2024年第9期19卷 1919-1928页

作者： Rosa Vázquez-Lizarraga Lucia mendoza-Viveros Carolina Cid-Castro Sareni Ruiz-montoya Erick Carreño-Vázquez Ricardo Orozco-Solis instituto Nacional de medicina Genómica(iNmEGEN) México CityMéxico Centro de investigacíon sobre el Envejecimiento Centro de Investigacíon y de Estudios Avanzados(CIE-CINVESTAV)México CityMéxico instituto de investigaciones Biomédicas Universidad Nacional Autónoma de México UNAMMéxico CityMéxico

Over the past century,age-related diseases,such as cancer,type-2 diabetes,obesity,and mental illness,have shown a significant increase,negatively impacting overall quality of *** on aged animal models have unveiled a progressive discoordination at multiple regulatory levels,including transcriptional,translational,and post-translational processes,resulting from cellular stress and circadian *** circadian clock emerges as a key regulator,sustaining physiological homeostasis and promoting healthy aging through timely molecular coordination of pivotal cellular processes,such as stem-cell function,cellular stress responses,and inter-tissue communication,which become disrupted during *** the crucial role of hypothalamic circuits in regulating organismal physiology,metabolic control,sleep homeostasis,and circadian rhythms,and their dependence on these processes,strategies aimed at enhancing hypothalamic and circadian function,including pharmacological and non-pharmacological approaches,offer systemic benefits for healthy *** brain-directed drug administration represents a promising avenue for effectively targeting specific brain regions,like the hypothalamus,while reducing side effects associated with systemic drug delivery,thereby presenting new therapeutic possibilities for diverse age-related conditions.

关键词： aging astrocytes cellular stress responses circadian clock hypothalamus intranasal drug administration metabolic control nutrient sensor SiRT1 sleep homeostasis

implications of regional identity for neural stem and progenitor cell transplantation in the injured or diseased nervous system

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Neural Regeneration Research 2024年第4期19卷 715-716页

作者： Prakruthi Amar Kumar Jennifer N.Dulin Department of Biology Texas A&M UniversityCollege Station Texas A&m institute for Neuroscience Texas A&M UniversityCollege Station

Neural stem and progenitor cell(NSPC)transpla ntation has emerged as a promising therapeutic strategy for replacing lost neuronal populations and repairing damaged neural circuits following nervous system injury and disease.A great deal of experimental work has investigated the biology of NSPC grafting in preclinical animal models;more recently.

关键词： neural system injured

High CO_(2)permeation using a new Ce_(0.85)Gd_(0.15)O_(2-δ)-LaNiO_(3)composite ceramic–carbonate dual-phase membrane

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Journal of Environmental Sciences 2024年第6期140卷 219-229页

作者： Daniela González-Varela JFrancisco Gómez-García Gustavo Tavizon Heriberto Pfeiffer instituto de investigaciones en materiales Universidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico Departamento de Física y Química Teórica Facultad de QuímicaUniversidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico 不详

This work shows the synthesis,characterization and evaluation of dense-ceramic membranes made of Ce_(0.85)Gd_(0.15)O_(2-δ)-LaNiO_(3)(CG-LN)composites,where the fluorite-perovskite ratio(CG:LN)was varied as follows:75:25,80:20 and 85:15 wt.%.Supports were initially characterized by XRD,SEm and electrical conductivity(using vacuum and oxygen atmospheres),to determine the composition,microstructural and ionic-electronic conductivity ***,supports were infiltrated with an eutectic carbonates mixture,producing the corresponding dense dual-phase membranes,in which CO_(2)permeation tests were ***,CO_(2)permeation experiments were performed from 900 to 700℃,in the presence and absence of oxygen(flowed in the sweep membrane side).Results showed that these composites possess high CO_(2)permeation properties,where the O_(2)addition significantly improves the ionic conduction on the sweep membrane ***,the GC80-LN20 composition presented the best results due to the following physicochemical characteristics:high electronic and ionic conductivity,appropriate porosity,interconnected porous channels,as well as thermal and chemical stabilities between the composite support and carbonate phases.

关键词： CO_(2)permeation Doped CeO_(2) LaNiO_(3) impedance Ceramic carbonate membrane