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Accuracy of combi.ed PET/CT i. i.age-gui.ed i.terventi.ns of li.er lesi.ns: An ex-vi.o study

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World Journal of Gastroenterology 2006年第15期12卷 2388-2393页

作者： Patri.k Vei. Chri.ti.ne Kuehle Thomas Beyer Hi.mar Kuehl Andreas Bocki.ch Gerald Antoch department of Di.gnosti. and i.terventi.nal Radi.logy and Neuroradi.logy department of Nuclear Medi.i.e Uni.ersi.y Hospi.al Essen

Ai.： Posi.i.ni.g of i.terventi.nal devi.es i. li.er lesi.ns i. a challengi.g task i. only CT i. avai.able. We i.vesti.ated the potenti.l benefi. of combi.ed PET/CT i.ages for locali.ati.n of i.terventi.nal devi.es i. i.terventi.nal li.er studi.s. METHODS： Thi.ty lesi.ns each of hyperdense, i.odense and hypodense attenuati.n compared to normal li.er parenchyma were i.jected i.to 15 ex-vi.o pi. li.ers. All lesi.ns were composed of the same amounts of gelati.e contai.i.g 0.5 MBq of ^18F-FDG. Followi.g lesi.n i.serti.n, an i.terventi.nal needle was placed i. each lesi.n under CT-gui.ance solely. After that, a PET/CT study was performed. The locali.ati.n of the needle wi.hi. the lesi.n was assessed for CT alone and PET/CT and the root mean square （RMS） was calculated. Results were compared wi.h macroscopi. measurements after lesi.n di.secti.n servi.g as the standard of reference. RESULTS： i. hypo- and i.odense lesi.ns PET/CT proved more accurate i. defi.i.g the posi.i.n of the i.terventi.nal devi.e when compared wi.h CT alone. The mean RMS for CT and PET/CT di.fered si.ni.i.antly i. i.odense and hypodense lesi.ns. No si.ni.i.ant di.ference was found for hyperdense lesi.ns. CONCLUSi.N： Combi.ed FDG-PET/CT i.agi.g provi.es more accurate i.formati.n than CT alone concerni.g the needle posi.i.n i. FDG-PET posi.i.e li.er lesi.ns. Therefore combi.ed PET/CT mi.ht be potenti.lly benefi.i.l not only for locali.ati.n of an i.terventi.nal devi.e, but may also be benefi.i.l for gui.ance i. i.terventi.nal li.er procedures.

关键词： Li.er bi.psy Radi.frequency ablati.n Combi.ed PET/CT ex-vi.o study i.age gui.ed i.terventi.ns

Neuronal-li.e di.ferenti.ti.n of bone marrow-deri.ed mesenchymal stem cells i.duced by stri.tal extracts from a rat model of Parki.son's di.ease

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Neural Regenerati.n Research 2012年第34期7卷 2673-2680页

作者： Xi.oli.g Qi. Wang Han Zhi.ang Yu department of Neurology Xuzhou Central Hospital department of Emergency Dongying People's Hospital

A rat model of Parki.son＇s di.ease was establi.hed by 6-hydroxydopami.e i.jecti.n i.to the medi.l forebrai. bundle. Bone marrow-deri.ed mesenchymal stem cells （BMSCs） were i.olated from the femur and ti.i., and were co-cultured wi.h 10% and 60% lesi.ned or i.tact stri.tal extracts. The results showed that when exposed to lesi.ned stri.tal extracts, BMSCs developed bi.olar or multi.polar morphologi.s, and there was an i.crease i. the percentage of cells that expressed gli.l fi.ri.lary aci.i. protei. （GFAP）, nesti. and neuron-speci.i. enolase （NSE）. Moreover, the percentage of NSE-posi.i.e cells i.creased wi.h i.creasi.g concentrati.ns of lesi.ned stri.tal extracts. However, i.tact stri.tal extracts only i.creased the percentage of GFAP-posi.i.e cells. The fi.di.gs suggest that stri.tal extracts from Parki.son＇s di.ease rats i.duce BMSCs to di.ferenti.te i.to neuronal-li.e cells i. vi.ro.

关键词： bone marrow-deri.ed mesenchymal stem cell Parki.son's di.ease stri.tal extract i.duceddi.ferenti.ti.n nerve cell gli.l fi.ri.lary aci.i. protei. nesti. neuron-speci.i. enolase neural stemcell regenerati.n neural regenerati.n

Effect of i.duced magneti. fi.ld on natural convecti.n i. verti.al concentri. annuli

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Acta Mechani.a Si.i.a 2012年第2期28卷 315-323页

作者： R.K.Si.gh A.K.Si.gh department of Mathemati.s Central University of BiharPatnaIndia department of Mathemati.s Banaras Hindu UniversityVaranasiIndia

i. the present paper, we have consi.ered the steady fully developed lami.ar natural convecti.e flow i. open ended verti.al concentri. annuli.i. the presence of a ra- di.l magneti. fi.ld. The i.duced magneti. fi.ld produced by the moti.n of an electri.ally conducti.g flui. i. taken i.to account. The transport equati.ns concerned wi.h the con- si.ered model are fi.st recast i. the non-di.ensi.nal form and then uni.i.d analyti.al soluti.ns for the veloci.y, i.duced magneti. fi.ld and temperature fi.ld are obtai.ed for the cases of i.othermal and constant heat flux on the i.ner cyli.- der of concentri. annuli. The effects of the vari.us phys- i.al parameters appeari.g i.to the model are demonstrated through graphs and tables. i. i. found that the magni.ude of maxi.um value of the flui. veloci.y as well as i.duced magneti. fi.ld i. greater i. the case of i.othermal condi.i.n compared wi.h the constant heat flux case when the gap be- tween the cyli.ders i. less or equal to 1.70 ti.es the radi.s of i.ner cyli.der, whi.e reverse trend occurs when the gap between the cyli.ders i. greater than 1.71 ti.es the radi.s of i.ner cyli.der. These fi.lds are almost the same when the gap between the cyli.ders i. equal to 1.71 ti.es the radi.s of i.ner cyli.der for both the cases. i. i. also found that as the Hartmann number i.creases, there i. a flatteni.g ten- dency for both the veloci.y and the i.duced magneti. fi.ld. The i.fluence of the i.duced magneti. fi.ld i. to i.crease the veloci.y profi.es.

关键词： Natural convecti.n i.othermal Heat flux Ski.-fri.ti.n i.duced magneti. fi.ld Magnetohydrody- nami.s

Prevalence of Anemi. i. Pati.nts wi.h COPD and i.s Potenti.l i.pact on Morbi.i.y of COPD Pati.nts

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i.ternati.nal Journal of Cli.i.al Medi.i.e 2014年第8期5卷 452-458页

作者： Shaheena Parveen i.ran Rangreze Syed Ni.ar Ahmad Showkat Ali.Mufti.Shehla Shafi.Khan Armed Force Hospi.al Southern Region Khamis Mushayt KSA department of Medi.i.e King Khalid University Abha KSA department of Medi.i.e Sher-i-Kashmir Institute of Medical Sciences Soura India Departmrent of Medi.al Oncology Sher-i-Kashmir Institute of Medical Sciences Soura India Departmrnt of Gastroenterology Sher-i-Kashmir Institute of Medical Sciences Soura India

Background: Although COPD i. tradi.i.nally associ.ted wi.h polycythemi., the systemi. i.flammati.n that i. now recogni.ed as a feature of COPD makes i. a possi.le cause of Anemi. of Chroni. Di.ease (ACD). Preli.i.ary evi.ences suggest that anemi. i. COPD may be more prevalent than expected occurri.g i. 10% - 15% of pati.nts. Whi.e i. states li.e chroni. heart fai.ure and renal i.suffi.i.ncy, anemi. has been extensi.ely studi.d;li.tle attenti.n has been gi.en to i. i. COPD. Objecti.es: To see the prevalence of anemi. i. pati.nts wi.h COPD and i.s potenti.l i.pact on morbi.i.y of COPD pati.nts. Desi.n and Setti.g: A uni.ersi.y hospi.al-based cross-secti.nal study i. Kashmi., i.di.. Methods: Two hundred pati.nts (119 males and 81 females) wi.h spi.ometery documented COPD were evaluated for frequency of anemi.. i. addi.i.n to routi.e i.vesti.ati.ns, erythropoi.ti. levels were done i. a subgroup of pati.nts. Results: A total of 36 cases (20 males and 16 females) of anemi. were detected gi.i.g a frequency of 18%. Normocyti. normochromi. type of anemi. was present i. 32 (88.89%) pati.nts whi.e the rest had normocyti. hypochromi. type of anemi.. Majori.y of pati.nts were i. GOLD stage 11 and had decreased serum i.on, transferri. saturati.n and Ti.C. Erythropoi.ti. levels were si.ni.i.antly rai.ed i. anemi. COPD pati.nts compared to non-anemi. COPD pati.nts. The vari.us factors si.ni.i.antly associ.ted wi.h anemi. were: No. of exacerbati.ns of COPD, No. of hospi.al admi.si.ns, BMi.and erythropoi.ti. levels. Conclusi.n: Anemi. occurs frequently i. pati.nts of COPD and i. associ.ted wi.h i.creased morbi.i.y i. the form of No. of exacerbati.ns and hospi.al admi.si.ns. Correcti.g anemi. i. these pati.nts may i.prove thei. cli.i.al outcome.

关键词： COPD Anemi.

Effect of Plant Densi.y on Wi.d Oat Competi.i.n wi.h Competi.i.e and Non-Competi.i.e Wheat Culti.ars

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Agri.ultural Sci.nces i. Chi.a 2011年第10期10卷 1554-1561页

作者： Mohammad Armi. Mohammed Asghri.our department of Agronomy Sabzevar Branch Islamic Azad University department of Agri.ulture University of Zabol

Wi.d oat （Avena ludovi.i.na） i. one of the worst weeds i. wheat fi.lds. The effect of wheat densi.y on wi.d oat competi.i.n wi.h more or less competi.i.e wheat culti.ars （Tri.i.um aesti.um） was i.vesti.ated at the Experi.ental Farm of Plant Pests and Di.eases Research i.sti.ute, Karaj, i.an. The experi.ent was establi.hed as a factori.l combi.ati.n of wheat vari.ti.s Roshan as non-competi.i.e and Ni.nejad as competi.i.e; three wheat densi.i.s （recommended densi.y, recommended＋25%, and recommended＋50%, correspondi.g respecti.ely wi.h 300, 375, and 450 plants m-2 for Roshan and 400, 500, and 600 plants m-2 for Ni.nejad） and four wi.d oat densi.i.s （0, 25, 50, and 75 plants m-2） were selected for thi. experi.ent. Hyperboli. equati.ns were used to descri.e relati.nshi. between yi.ld and weed densi.y. i.crease i. wheat densi.y reduced wi.d oat bi.mass. Maxi.um wi.d oat bi.mass was achi.ved at the hi.hest densi.y of the wi.d oat together wi.h the lowest wheat densi.y. The results showed that hi.her densi.i.s of wheat are able to suppress wi.d oat dry matter producti.n. i.ter-speci.i. competi.i.n i. Ni.nejad was 1.7 ti.es more than that i. Roshan. Maxi.um yi.lds of Ni.nejad and Roshan i. the presence of wi.d oat were obtai.ed at recommended densi.y＋25% and recommended densi.y, respecti.ely. i.crease i. wheat densi.y leads to a decrease i. wheat yi.ld due to an i.crease i. i.tra-speci.i. competi.i.n. i.crease i. wi.d oat densi.y results i. the reducti.n of wheat yi.ld through decrease i. ferti.e ti.ler per plant and spi.e m-2.

关键词： competi.i.n plant densi.y wheat wi.d oat yi.ld

Mi.rostructural Morphologi.s and Experi.ental Growth Laws duri.g Soli.i.i.ati.n of Monotecti. and Hypermonotecti. Al-Pb Alloys

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Journal of Materi.ls Sci.nce & Technology 2014年第4期30卷 401-407页

作者： Adri.a P.Si.va Amauri.Garci. José E.Spi.elli department of Materi.ls Engi.eeri.g University of Campinas-UNICAMP department of Materi.ls Engi.eeri.g Federal University of Sao Carlos-UFSCar

Ai.Pb alloys wi.h monotecti. and hypermonotecti. composi.i.ns were di.ecti.nally soli.i.i.d under unsteady- state heat flow condi.i.ns. The cooli.g curves recorded duri.g soli.i.i.ati.n allowed soli.i.i.ati.n thermal parameters such as the cooli.g rate （T）, growth rate （v） and thermal gradi.nt （G） to be experi.entally determi.ed. Di.ferent mi.rostructural patterns have been associ.ted wi.h the alloy solute content, i.e., Ai.1.2 and 2.1 wt% Pb. A sequence of morphologi.s from the bottom to the top of the A1-1.2 wt% Pb alloy casti.g （monotecti.） can be observed： Pb-ri.h droplets i. the alumi.um-ri.h matri., followed by a regi.n of mi.rostructural transi.i.n formed by droplets and fi.ers and fi.ally by a mi.ture of fi.ers and stri.gs of pearls. A completely fi.rous structure （wi.hout transi.i.n） has been observed along the enti.e Ai.2.1 wt% Pb alloy casti.g （hypermonotecti.）. The i.terphase spaci.g （λ） was measured along the casti.g length, and experi.ental correlati.ns between λand experi.ental soli.i.i.ati.n thermal parameters have been establi.hed. Power laws wi.h a -2.2 exponent expressi.g λ as a functi.n of the growth rate, v, were found to better represent the fi.rous growth of both Ai.Pb alloys. Moreover, a si.gle experi.ental law expressi.g λ as a functi.n of both G and v was found to descri.e the fi.rous growth of both the monotecti. and the hypermonotecti. alloys experi.entally exami.ed.

关键词： Alumi.um alloys Casti.g Phase transformati.n

Symmetry groups and Gauss kernels of Schrdi.ger equati.ns

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Chi.ese Physi.s B 2012年第2期21卷 66-75页

作者： Kang Ji.g Qu Chang-Zheng department of Mathemati.s Northwest UniversityXi'an 710069China department of Mathemati.s Ningbo UniversityNingbo 315211China

The relati.nshi. between symmetri.s and Gauss kernels for the SchrSdi.ger equati.n i.t = uxx ＋ f（x）u i. establi.hed. i. i. shown that i. the Li. poi.t symmetri.s of the equati.n are nontri.i.l, a classi.al i.tegral transformati.ns of the Gauss kernels can be obtai.ed. Then the Gauss kernels of Schroedi.ger equati.ns are deri.ed by i.verti.g the i.tegral transformati.ns. Furthermore, the relati.nshi. between Gauss kernels for two equati.ns related by an equi.alence transformati.n i. i.enti.i.d.

关键词： Schroedi.ger equati.n symmetry group Gauss kernel equi.alence transformati.n

Di.ect and rapi. detecti.n of serum ami.o aci. and monoami.e neurotransmi.ters to assi.t the di.gnosi. of pani. di.order

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Sci.nce Chi.a Chemi.try 2025年第1期 377-384页

作者： Shi.en Li. Xuerui.Wan Meng Zhao Ji.qi.Wang Wei.an Wu Li.li. You Yonggui.Yuan Qi.n Xu Rong Gao Key Laboratory of Envi.onmental Medi.i.e Engi.eeri.g Ministry of Education School of Public Health Southeast University Key Laboratory of Modern Toxi.ology of Mi.i.try of Educati.n Department of Hygienic Analysis and Detection School of Public HealthNanjing Medical University department of Psychosomati.s and Psychi.try Zhongda Hospital School of Medicine Southeast University

The measurement of ami.o aci. and monoami.e neurotransmi.ters（NTs） i. serum plays a central role i. the i.enti.i.ati.n and moni.ori.g of cli.i.al pani. di.order（PD）. However, the strong polari.y and chemi.al heterogenei.y of NTs make di.ect extracti.n and rapi. detecti.n extremely challengi.g. Herei., we developed a strategy that i.tegrated soli. phase extracti.n based on magneti. Fe3O4coated wi.h polydopami.e（Fe3O4@PDA） and di.ect analysi. of mass spectrometry i. real ti.e（DART-MS） for quanti.i.ati.n of 10 NTs. We systemati.ally i.vesti.ated the opti.al condi.i.ns of thi. strategy to achi.ve good accuracy and preci.i.n. Compared wi.h exi.ti.g magneti. soli. phase extracti.n methods for NTs detecti.n i. bi.logi.al samples, thi. strategy could adsorb more targets whi.e havi.g si.i.ar adsorpti.n effi.i.nci.s, and the total process ti.e was reduced by an average of 69.42%. We rapi.ly determi.ed the metaboli. abnormali.y of 6 types of NTs i. the serum of PD pati.nts and demonstrated thei. di.gnosti. accuracy. i. addi.i.n, an outstandi.g feature of PD i. whi.h tryptophan was more metaboli.ed by the KYN pathway and the 5-hydroxytryptami.e pathway was i.hi.i.ed could be eluci.ated by thi. strategy. Our results hi.hli.hted the potenti.l abi.i.y of Fe3O4@PDA coupled wi.h DART-MS to assi.t i. the cli.i.al di.gnosi. of PD.

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Follow-up of pati.nts wi.h functi.nal bowel symptoms treated wi.h a low FODMAP di.t

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World Journal of Gastroenterology 2016年第15期22卷 4009-4019页

作者： Loui.e Maagaard Dori. V Ankersen Zsuzsanna Végh Johan Buri.ch Li.beth Jensen Natali. Pedersen Pi. Munkholm department of Gastroenterology North Zealand University Hospital Fi.st department of Medi.i.e Semmelweis University department of Gastroenterology Hvidovre University Hospital department of Gastroenterology Herlev University Hospital department of Gastroenterology Slagelse University Hospital

Ai.: To i.vesti.ate pati.nt-reported outcomes from, and adherence to, a low FODMAP di.t among pati.nts sufferi.g from i.ri.able bowel syndrome and i.flammatory bowel ***: Consecuti.e pati.nts wi.h i.ri.able bowel syndrome(i.S) or i.flammatory bowel di.ease(i.D) and co-exi.ti.g i.S fulfi.li.g the ROME Ⅲ cri.eri., who previ.usly attended an outpati.nt cli.i. for low FODMAP di.t(LFD) di.tary management and assessment by a gastroenterologi.t, were i.vi.ed to parti.i.ate i. a retrospecti.e questi.nnai.e analysi.. The questi.nnai.es were sent and returned by regular mai. and gathered i.formati.n on recall of di.tarytreatment, effi.acy, symptoms, adherence, sati.facti.n, change i. di.ease course and stool type, and quali.y of li.e. Before study enrolment all pati.nts had to si.n an i.formed wri.ten ***: One hundred and ei.hty pati.nts were i.cluded, 131(73%) i.S and 49(27%) i.D pati.nts. Medi.n age was 43 years(range: 18-85) and 147(82%) were females. Medi.n follow-up ti.e was 16 mo(range: 2-80). Ei.hty-si. percent reported ei.her parti.l(54%) or full(32%) effi.acy wi.h greatest i.provement of bloati.g(82%) and abdomi.al pai.(71%). The proporti.n of pati.nts wi.h full effi.acy tended to be greater i. the i.D group than i. the i.S group(42% vs 29%, P = 0.08). There was a si.ni.i.ant reducti.n i. pati.nts wi.h a chroni. conti.uous di.ease course i. both the i.S group(25%, P i.D group(23%, P = 0.002) along wi.h a si.ni.i.ant i.crease i. pati.nts wi.h a mi.d i.dolent di.ease course of 37%(P i.ely. The proporti.n of pati.nts havi.g normal stools i.creased wi.h 41% i. the i.S group(P i. the i.D group(P i.d of pati.nts adhered to the di.t and hi.h adherence was associ.ted wi.h longer durati.n of di.tary course(P i.facti.n wi.h di.tary management was seen i. 83(70%) i.S pati.nts and 24(55%) i.D pati.nts. Ei.htyfour percent of pati.nts li.ed on a modi.i.d LFD, wher

关键词： Low FODMAP i.ri.able bowel syndrome i.flammatory bowel di.ease Adherence Di.ease course