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Effects of Exposure to GSM Mobile Phone Base Station Signals on Salivary Cortisol,Alpha-Amylase,and Immunoglobulin A

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Biomedical and Environmental Sciences 2010年第3期23卷 199-207页

作者： CHRISTOPH AUGNER GERHARD W.HACKER GERD OBERFELD MATTHIAS FLORIAN WOLFGANG HITZL JORG HUTTER GERNOT PAUSER IGGMB-Research Institute for Frontier Questions of Medicine and Biotechnology Salzburg Federal Hospital-University Clinics of the Paracelsus Medical Private UniversitySalzburg Federal Clinics(SALK)SalzburgAustria Public Health Department Salzburg SalzburgAustria Research office Paracelsus Medical Private UniversityComma SalzburgAustria university Clinic of Surgery Salzburg Federal Hospital University Clinics of the Paracelsus Medical Private UniversitySalzburg Federal Clinics(SALK)SalzburgAustria university Clinic for Anesthesiology Perioperative Medicine and General Intensive CareSalzburg Federal Hospital-University Clinics of the Paracelsus Medical Private UniversitySalzburg Federal Clinics(SALK)SalzburgAustria

Objective The present study aimed to test whether exposure to radiofrequency electromagnetic fields （RF-EMF） emitted by mobile phone base stations may have effects on salivary alpha-amylase, immunoglobulin A （IgA）, and cortisol levels. Methods Fifty seven participants were randomly allocated to one of three different experimental scenarios （22 participants to scenario 1, 26 to scenario 2, and 9 to scenario 3）. Each participant went through five 50-minute exposure sessions. The main RF-EMF source was a GSM-900-MHz antenna located at the outer wall of the building. In scenarios 1 and 2, the first, third, and fifth sessions were ＂low＂（median power flux density 5.2 μW/m^2） exposure. The second session was ＂high＂（2126.8 μW/m^2）, and the fourth session was ＂medium＂（153.6 μW/m^2） in scenario 1, and vice versa in scenario 2. Scenario 3 had four ＂low＂ exposure conditions, followed by a ＂high＂ exposure condition. Biomedical parameters were collected by saliva samples three times a session. Exposure levels were created by shielding curtains. Results In scenario 3 from session 4 to session 5 （from ＂low＂ to ＂high＂ exposure）, an increase of cortisol was detected, while in scenarios 1 and 2, a higher concentration of alpha-amylase related to the baseline was identified as compared to that in scenario 3. IgA concentration was not significantly related to the exposure. Conclusions RF-EMF in considerably lower field densities than ICNIRP-gnidelines may influence certain psychobiological stress markers.

关键词： GSM base stations Mobile phone Salivary IgA Alpha amylase Cortisol Radiofrequency electromagnetic fields (RF-EMF)

Effectiviness, Safety and Satisfaction in Teleurology

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Open Journal of Urology 2022年第7期12卷 383-393页

作者： Thome Barros Junior Marcos Kalaf Farah Albeny Igor José Caetano De Lima Guilherme Bastos Palitot De Brit Moacir Cavalcante De Albuquerque Neto Fábio Oliveira Vilar federal university of pernambuco Recife Brazil hospital of clinics of federal university of pernambuco Recife Brazil

Introduction: Telemedicine has been used as a tool for improving access to health services worldwide. The aim of the present study is thus to evaluate the effectiveness of urological consultation by videoconference, perceptions regarding safety on the part of medical teams providing video consultation services and patient satisfaction after a urological appointment. Materials and Methods: A cross-sectional, observational, and analytical study was carried out with 50 volunteers referred from the basic health unit for a urology appointment. All patients were evaluated remotely by videoconference and in person by different urology teams. Results: The study revealed that effectiveness in terms of the degree of match between diagnoses performed by video consultation and those performed in person was 92%. The urology team’s perception regarding safety, measured using an in-house safety questionnaire, was high for both videoconferencing and in-person consultations and there was no statistical difference between the two (overall safety score for video consultation compared to in-person consultation was 9.7 ± 0.8 compared to 9.6 ± 0.8 and the p-value was 0.3 for Student’s t-test). Patient satisfaction with the appointment was similarly high for both groups, averaging 9.72 ± 0.4 among patients who attended a video consultation and 9.82 ± 0.4 among those whose consultation was conducted in person, with a p-value of 0.10478 for Student’s t-test. Conclusion: Video consultation in urology is an effective way to perform diagnoses, with high levels of perceived safety among urologists and high satisfaction rates among patients.

关键词： Urology Telemedicine Telecommunications Appointments and Schedules

Mechanisms and consequences of COVID-19 associated liver injury: What can we affirm?

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World Journal of Hepatology 2020年第8期12卷 413-422页

作者： Carlos Antunes Brito Fabio Marinho Barros Edmundo Pessoa Lopes Department of Internal Medicine Center of Medical Sciences of Federal University of PernambucoRecifePernambuco 50740600Brazil Clinical hospital of federal university of pernambuco RecifePernambuco 50740900Brazil Post-graduation Program of Tropical Medicine of federal university of pernambuco RecifePernambuco 50670901Brazil Autoimmune Research Institute RecifePernambuco 52011010Brazil Português hospital of pernambuco RecifePernambuco 52010075Brazil

Since the first reports of coronavirus disease 2019(COVID-19)cases in December 2019 in China,numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection,many of them proposing a link between these findings and patient *** in serum aminotransferase levels(ranging from 16%to 62%)and bilirubin levels(ranging from 5%to 21%)have been reported and seem to be more often observed in patients with severe forms of *** absolute changes in these parameters are frequently seen,other variables,such as the ratio above the upper limit of normal,the onset of liver injury as a complication in severe cases and histopathological findings,reinforce that liver changes are of dubious clinical relevance in the course of this *** factors must also be considered in these analyses,such as the repercussions of hemodynamic changes,the presence of thrombotic events,and,mainly,the possible drug-induced liver injury with the current,yet off-label,*** paper aimed to analyze the currently available data on liver injury in patients with COVID-19.

关键词： COVID-19 SARS-CoV-2 Liver injury Liver enzymes Drug induced liver injury Pandemic

Biopolymer Sponge for High Grade Renal Trauma: An Experimental Study in Rabbits

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Open Journal of Urology 2014年第1期4卷 1-6页

作者： Leandro H. M. Tavares Fábio O. Vilar José L. Aguiar Alexandre R. Paz Francisco A. D. Melo Gustavo R. P. Negromonte Department of Surgery Federal University of Paraiba University Hospital Lauro Wanderley Joao Pessoa Brazil Department of Surgery Federal University of Pernambuco Clinics Hospital Recife Brazil

Introduction: Acute blunt or open renal trauma sometimes requires conservative measure which involves the use of specific materials in order to adequately restore renal parenchima. The purpose of this study is to analyze the effects of the sugar cane biopolymer sponge in an experimental model of renal trauma in rabbits. Methods: Experimental prospective study was paired with twelve New Zealand rabbits. After induction of renal trauma bilateral high-grade (grade 4-collecting system, according to AAST), the sugar cane biopolymer sponge was used for homeostasis and reconstruction of the right renal parenchyma (experimental group). The same procedure was performed in the left kidney, but using the Surgifoam? sponge (Control Group). The animals were sacrificed after four weeks. Histological analysis was performed and the results were compared after statistically being evaluated. Results: Comparing the experimental group with the control, there was more inflammatory reaction and premature adhesions in the first one. Concerning the influence on efficacy and biocompatibility of the biopolymer, no serious complications like massive bleeding, haematoma, fistula or urinary stone formation were found in both groups. Conclusion: The sugar cane biopolymer sponge demonstrated good efficacy in relation to hemostatic control and reconstruction of the renal parenchyma without major complications. Future studies may direct its routine use in urologic practice.

关键词： Acute Renal Injury Surgical Hemostasis Absorbable Implants Inflammation Biocompatible Materials

Identification of Trichosporon spp. Strains by Sequencing D1/D2 Region and Sub-typing by Sequencing Ribosomal Intergenic Spacer Region of Ribosomal DNA

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Journal of Huazhong university of Science and Technology(Medical Sciences) 2009年第5期29卷 655-658页

作者：曾敬思 Cristina Mariade Souza Motta 福岛和贵龙泽香代子 Oliane Maria Correia Magalhes Rejane Pereira Neves 西村和子 Department of Dermatology and Venereology Union HospitalTongji Medical CollegeHuazhong University of Science and Technology federal university of pernambuco Av.Prof.Chavess/nCEP:50670-420RecifePernambucoBrazil Medical Mycology Research Center Chiba University

To re-identify and further group 25 isolates of Trichosporon spp. identified morphologically previously, sequences of D1/D2 region of large subunit （LSU） of ribosomal DNA （rDNA） of 25 tested strains for identification and those of ribosomal intergenic space 1 （IGS1） region of 11 strains for subgrouping were detected. The identifications of tested strains were changed except 6 strains. According to the alignment of the IGS1 region, 6 T. asahii isolates tested fell into 4 groups and 5 T. faecale isolates into 3 groups. Polymorphism of 2 T. japonicum isolates was found in 10 positions. With the alignments obtained in this research compared with the relative GenBank entries, it was found that T. asahii, T. faecale and T. japonicum species were divided into 7, 3 and 2 subtypes respectively. Morphological and biophysical methods are not sufficient for Trichosporon spp. identification. Sequencing becomes necessary for Trichosporon diagnosis. There is obvious diversity within a species.

关键词： Trichonsporon large subunit D1/D2 intergenic space 1

Assessment of periportal fibrosis in Schistosomiasis mansoni patients by proton nuclear magnetic resonance-based metabonomics models

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World Journal of Hepatology 2022年第4期14卷 719-728页

作者： Milena Lima Rodrigues Tatiane Priscila Santos Rodrigues da Luz Caroline Louise Diniz Pereira Andrea Dória Batista Ana Lúcia Coutinho Domingues Ricardo Oliveira Silva Edmundo Pessoa Lopes Programa de Pós-Graduação em Medicina Tropical Centro de Ciências MédicasUniversidade Federal de PernambucoRecife 50670-901PernambucoBrazil Programa de Pós-Graduação em Química Centro de Ciências Exatas e da NaturezaUniversidade Federal de PernambucoRecife 50670-740PernambucoBrazil hospital das Clínicas Departamento de Medicina ClínicaUniversidade Federal de PernambucoRecife 50670-901PernambucoBrazil

BACKGROUND The evaluation of periportal fibrosis(PPF)is essential for a prognostic assessment of patients with Schistosomiasis *** WHO Niamey Protocol defines patterns of fibrosis from abdominal ultrasonography,^(1)H-nuclear magnetic resonance(NMR)-based metabonomics has been employed to assess liver fibrosis in some *** To build 1H-NMR-based metabonomics models(MM)to discriminate mild from significant periportal PPF and identify differences in the metabolite *** A prospective cross-sectional study was performed on schistosomiasis patients at a university hospital in Northeastern *** evaluated 41 serum samples from 10 patients with mild PPF(C Niamey pattern)and 31 patients with significant PPF(D/E/F Niamey patterns).MM were built using partial least squares-discriminant analysis(PLS-DA)and orthogonal projections to latent structures discriminant analysis(OPLS-DA)*** PLS-DA and OPLS-DA resulted in discrimination between mild and significant PPF groups with R2 and Q2 values of 0.80 and 0.38 and 0.72 and 0.42 for each model,*** OPLS-DA model presented accuracy,sensitivity,and specificity values of 92.7%,90.3%,and 100%to discriminate significant *** metabolites identified as responsible by discrimination were:Nacetylglucosamines,alanine,glycolaldehyde,carbohydrates,and *** MMs discriminated mild from significant PPF patterns in patients with Schistosomiasis mansoni through identification of differences in serum metabolites profiles.

关键词： Metabolomics Portal hypertension Schistosoma mansoni Biomarkers Neglected disease Nuclear magnetic resonance

Clinical Analysis of a Coaxial Dilator Set Attached to Needle Puncture for Percutaneous Nephrolithotomy

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Open Journal of Urology 2013年第6期3卷 248-252页

作者： Evandilson Guenes Campos de Barros Salvador Vilar Correia Lima Fabio de Oliveira Vilar Eugenio Soares Lustosa Roberto Santos Lima Department of Surgery Federal University of Pernambuco Pernambuco Brazil Master’s Program of Post Graduation in Surgery Center of Health Sciences Federal University of Pernambuco Pernambuco Brazil Member of the Brazilian Society of Urology Recife Brazil Urology Service of the hospital das Clinicas Federal University of Pernambuco Pernambuco Brazil

Introduction: Percutaneous approach to the kidney is a very useful alternative in renal surgery which minimizes the morbidity of a variety of procedures. Objectives: To evaluate the efficacy, practicity of a reusable system of metallic coaxial dilator coupled to a special puncture needle to perform lumbar puncture and dilation of the percutaneous tract. Methods: A randomized experimental study was carried out involving 50 individuals. These patients were randomized as follows: Group 1 had the procedure performed with the conventional disposable Amplatz set traditionally used for this procedure. Patients in Group 2 were operated utilizing the new reusable coaxial set specially designed for this purpose. The following parameters were measured to compare the 2 groups: sex Corporeal Mass Index (CMI), Pre and postoperative hematocrit and hemoglobin. Time interval between the puncture, dilation and access to the renal pelvis and insertion of the nephroscope were also analyzed. Results: There was no statistical difference between the 2 groups concerning hematocrit and hemoglobin changes when comparing prewith postoperative period. Patients in Group 2 required a significant lower time between puncture and final access to the upper collecting system. Conclusion: The new coaxial dilator set showed to be as safe as the conventional Amplatz set with the advantage of reusability and decrease of tract dilation time.

关键词： Percutaneous Nephrolithotomy Metallic Coaxial Dilator Kidney Stone

Cardiovascular risk burden and disability:findings from the International Mobility in Aging Study(IMIAS)

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Journal of Geriatric Cardiology 2024年第3期21卷 331-339页

作者： Juan-David Martinez-Aristizábal Carmen-Lucia Curcio Juliana Fernandes Afshin Vafael Cristiano dos Santos Gomes Fernando Gomez Internal Medicine Critical Care DepartmentPablo Tobón Uribe HospitalMedellínColombia Research Group in Geriatrics and Gerontology Faculty of Health SciencesUniversidad de CaldasManizalesColombia Laboratory of Physical Therapy and Collective Health Physical Therapy DepartmentFederal University of PernambucoJornalista Aníbal Fernandes Avenue RecifeBrazil Department of Public Health Sciences Queen’s UniversityKingstonONCanada Department of Physiotherapy University of PernambucoBR 203KmBrazil

BACKGROUND The association of cardiovascular risk burden with disability is *** examined the association between trajectories of the Framingham general cardiovascular disease risk score(FGCRS)with the trajectories of limitations of physical function in older *** A total of 1219 participants with no disabilities from the International Mobility in Aging Study(IMIAS)study who had up to three repeated measures of FGCRS between 2012–2016 and without a history of stroke or coronary heart disease at baseline and follow-up were *** at baseline was assessed and categorized into *** function was evaluated with the Short Physical Performance Battery(SPPB).The data were analyzed using linear mixed-effects *** At baseline,FGCRS ranged between 3–94(mean score:24±15.8),participants were 32(2.6%),502(41.2%)and 685(56.2%)in lowest,middle,and highest tertiles,*** the trajectories of limitations of physical function,the lowest FGCRS had no differences,while the middle and highest had a decrease in physical performance between 2012–2014(P=0.0001).Age,being female,living in Andes Mountains,having middle and highest FGCRS,higher alcohol consumption,being obese,lack of exercise and cognitive impairment increase the probability of disability(P<0.05).Alternatively,living in more developed regions and having a higher educational level reduced the probability of disability during the follow-up time(P<0.05).CONCLUSIONS Higher cardiovascular risk burden is associated with decreased physical performance,especially in *** suggest SPPB may provide a measure of cardiovascular health in older adults.

关键词： finding Battery burden

Risk of Surgical Site Infection in Patients Undergoing Total Knee Arthroplasty

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Open Journal of Orthopedics 2018年第7期8卷 305-315页

作者： Paulo Cezar Vidal Carneiro de Albuquerque Alvaro Antonio Bandeira Ferraz Clarissa Miranda Carneiro de Albuquerque Olbertz Jose Miguel Francisco da Silva Souza Alessandro Henrique da Silva Santos Paula Eduarda Miranda Carneiro de Albuquerque federal university of pernambuco RecifeBrazil Sarah Kubistckeck hospital BrasiliaBrazil IMIP RecifeBrazil

The aim of this study was to determine the participation of risk factors in the infection in patients who underwent total knee arthroplasty. This is a prospective longitudinal study, descriptive and analytical, that was carried out between January 2013 and December 2015. Eighty-one procedures were performed in 78 individuals, 16 males and 62 females. Three subjects underwent the procedure on both knees. The following predictive factors of infection were identified: Age, gender, comorbidities, evaluation of functional physical status using the American Society of Anesthesiologists Physical Status Classification System (ASAPS), length of hospital stay, use of prophylactic antibiotics and duration of surgery. The data was tabulated in a database using a Microsoft Excel spreadsheet. For statistical analysis, the chi-square test, chi-square test for independence and Fischer’s exact test were applied, all at a significance level of 5% (0.05). Surgical site infection was more prevalent in males (23.5%), age over 70 years (25.0%), for left gonarthrosis (17.9%), in the presence of comorbidities (17.9%), when hospital stay was 6 or more days (27.8%), in total arthroplasties of left knee (17,9%), in surgical times of up to 2 hours (20%), in the use of prophylactic antibiotics (16.7%) and in level II classification in the ASAPS (18.8%). The independence test was not significant in any of the evaluated factors (p-value greater than 0.05). The most prevalent bacteria identified in cases of infection was Staphylococcus aureus (33.2%). The risk factors studied were not statistically significant.

关键词： Knee Arthroplasty Knee Debridement Infection Joint Prosthetic Joint Infection/Diagnosis Infection Therapy