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Analysis of Perinatal Outcomes of Twin Pregnancy in a Referral hospital for High Risk

Open Journal of Obstetrics and Gynecology 2024年第7期14卷 983-995页

作者： eduarda Paim Pedro Lucas Carneiro Ferreira Luciano Selistre Fernanda Grossi José Mauro Madi Gabriela Françoes Rostirolla Mdica Residente do Programa de Residncia em Ginecologia e Obstetrcia Hospital Geral de Caxias do Sul Rio Grande do Sul Brasil faculdade de medicina Universidade de Caxias do Sul Rio Grande do Sul Brasil Programa de Ps-Graduao Universidade de Caxias do Sul Rio Grande do Sul Brasil Servio de Ginecologia e Obstetrcia Hospital Geral de Caxias do Sul Rio Grande do Sul Brasil

Introduction: The incidence of twin pregnancies has increased significantly in recent decades. These pregnancies require more attention due to their worse outcomes than singleton pregnancies. Objective: To analyze the characteristics and perinatal outcomes of twin pregnancies at the caxias do sul General hospital. Methods: This is a descriptive and retrospective study that included all births related to twin pregnancies between March 1998 and June 2018. Maternal and perinatal variables were analyzed. descriptive analyses were carried out using measures of central tendency and dispersion for continuous variables (mean and standard deviation or median and interquartile range), according to a prior assessment of distribution using the Shapiro-Wilk test, and absolute (n) and relative (n%) frequencies for categorical variables. Results: 172 pairs of twins/21,972 births (0.8%) were identified. There was a high percentage of interpartum interval of less than 12 months, adherence and prenatal visits, body mass index, and need for neonatal intensive care. Stillbirth and neomortality rates were within acceptable parameters. Conclusion: The sample studied showed a percentage similar to that in the literature, a high rate of maternal and perinatal complications, characterizing it as a high-risk fetal pregnancy.

关键词： Pregnancy Twin Pregnancy High Risk Pregnancy Morbidity Perinatal Mortality Perinatal Results

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Hereditary Angioedema in Pregnancy and Management without Recombinant Human C1-INH

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Open Journal of Obstetrics and Gynecology 2021年第11期11卷 1470-1476页

作者： Natália Paseto Pilati Maria Alexandrina Zanatta daniele Camila Maltauro Gabrielle Behenck edimárlei Gonsales Valério Fernanda Oliveira Castilhos eduardo Vettorazzi-Stuczynski daniela Vanessa Vettori Janete Vettorazzi Postgraduation Program in Health Sciences: Gynecology and Obstetrics (PPGGO) Faculdade de Medicina (FAMED) Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Rio Grande do Sul Brazil Service of Gynecology Hospital de Clinicas de Porto Alegre Porto Alegre Brazil hospital geral de caxias do sul e faculdade de medicina da universidade de caxias do sul Caxias do Sul Brazil

A pregnant woman diagnosed with type 1 angioedema seeks care at a public hospital for planning the delivery. This report presents ways to prevent and manage an acute HAe crisis during childbirth and early postpartum w... 详细信息

关键词： Hereditary Angioedema (HAe) C1-Inhibitor High-Risk Pregnancy Prophylaxis

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Midline Supraumbilical Incision as an Option for Morbidly Obese Patients? Case Report

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Open Journal of Obstetrics and Gynecology 2021年第11期11卷 1517-1523页

作者： Janete Vettorazzi Gabriela Françoes Rostirolla Gabrielle Soares Behenck Fernanda Oliveira Castilhos eduardo Vettorazzi-Stuczynski edimárlei Gonsales Valério Postgraduate Program in Health Sciences: Gynecology and Obstetrics Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brasil department of Gynecology and Obstetrics Faculdade de Medicina (FAMED) Universidade Federal do Rio Grande do Sul Porto Alegre-Rio Grande do Sul (RS) Brasil Service of Obstetrics and Gynecology Hospital de Clínicas de Porto Alegre Porto Alegre/RS Brasil hospital geral de caxias do sul e faculdade de medicina da universidade de caxias do sul Caxias do Sul/RS Brasil

Background: Nowadays we observe growing rates of obesity, mainly among women. It has a great impact on maternal and fetal morbimortality and requires a specific obstetric approach. Aim: To discuss different approaches to abdominal incision in cesarean section in obese patients. Case presentation: Patient with morbid obesity submitted to an elective cesarean section due to fetal macrosomia and who underwent a cesarean section with a supraumbilical median incision evolving without any postpartum complications. Conclusion: It’s important to evaluate and chose the best incision in morbidly obese pregnant women aiming to reduce difficulties in fetal extraction and postoperative complications. Midline supraumbilical incision is a good choice in these cases, reducing surgical time and postpartum hemorrhage.

关键词： Obesity Caesarean Section Surgical Incision Abdominal Obesity

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Interleukin 28B-related polymorphisms: A pathway for understanding hepatitis C virus infection?

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World Journal of Gastroenterology 2013年第42期19卷 7399-7404页

作者： Raquel Francine Liermann Garcia Simone Moreira Ana Lucia de Araújo Ramos Leslie ecker Ferreira Angelo Alves de Mattos Cristiane Valle Tovo Lysandro Alsina Nader Juliene Antonio Ramos edson Rondinelli Arnaldo de Jesus dominici Christian evangelista Garcia Mauro de Souza Leite Pinho Carlos eduardo Brando-Mello Cristiane Alves Villela-Nogueira Paulo Henrique Condeixa de Frana departamento de medicina Universidade da Regio de Joinville/UnivilleJoinville89219-719 Santa CatarinaBrazil departamento de Clinica Médica e Cirurgia geral hospital Municipal So José Joinville89202-000 Santa CatarinaBrazil departamento de Clínica Médica Servio de HepatologiaFaculdade de Medicina/Hospital Universitário Clementino Fraga Filho/Universidade Federal do Rio de Janeiro21941-913 Rio de JaneiroBrazil Servio de Gastroenterologia e Hepatologia Irmandade da Santa Casa de Misericórdia/ISCMPAPorto Alegre90020-090 Rio Grande do SulBrazil Servio de endoscopia Universidade Federal de Pelotas/UFPelPelotas96010-610 Rio Grande do SulBrazil Instituto de Biofísica Carlos Chagas Filho/UFRJ 21941-902 Rio de JaneiroBrazil departamento de Gastroenterologia Hospital Universitário da Universidade Federal do Maranh o/UFMASo Luis65020-560 MaranhoBrazil Servio de Gastroenterologia Hospital Universitário Gaffrée Guinle/HUGG/UNIRIO20270-004 Rio de JaneiroBrazil

AIM:To analyze the role of rs12979860 and rs8099917polymorphisms in hepatitis C virus(HCV)genotype 1infection of ***:A total of 145 adult patients diagnosed with genotype 1 chronic hepatitis C(CHC)who had completed a 48-wk regimen of pegylated-interferonα-2a or-2b plus ribavirin combination therapy were recruited from six large urban healthcare centers and199 healthy blood donors(controls)from a single site between January 2010 and January *** on the patients’response to treatment was *** chain reaction-restriction fragment length polymorphism genotyping of the interleukin(IL)28B gene fragment encompassing the single nucleotide polymorphisms(SNPs)rs12979860(C/T)and rs8099917(T/G)was carried out for 79 of the CHC patients and 199 of the ***-directional amplicon sequencing of the two SNPs was carried out for the remaining 66 CHC ***:SNP rs12979860 genotyping was successful in 99.5%of the controls and 97.2%of the CHC patients,whereas the SNP rs8099917 genotyping was successful in 95.5%of the controls and 100%of the CHC *** genotype and allele distributions for both rs12979860 and rs8099917 were significantly different between the control and CHC patient groups,with significantly higher genotype frequencies of CC and TT in the controls(P=0.037 and 0.046,respectively)and of TT and GG in the CHC patients(P=0.0009and 0.0001,respectively).Analysis of the CHC patients who achieved sustained virological response(SVR)to treatment(n=55)indicated that the rs12979860 C allele and CC genotype were predictors of SVR(P=0.02).No significant correlation was found between rs8099917 genotypes and treatment response,but carriers of the T allele showed significantly higher rates of SVR(P=0.02).Linkage disequilibrium analysis of the group that achieved SVR showed a significant association between rs12979860 and rs8099917(P=0.07).CONCLUSION:The higher allele frequency of rs12979860 C and rs8099917 T observed in non-HCVinfec

关键词： Hepatitis C Interleukin 28B Single nucleotide polymorphisms Sustained virological response Brazil

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